TP53 c.523_524delinsGC ;(p.R175A)

Variant ID: 17-7578406-CG-GC

NM_000546.5(TP53):c.523_524delinsGC;(p.R175A)

This variant was identified in 6 publications

View GRCh38 version.




Publications:


Structural and Drug Targeting Insights on Mutant p53.

Cancers
Gomes, Ana Sara AS; Ramos, Helena H; Inga, Alberto A; Sousa, Emília E; Saraiva, Lucília L
Publication Date: 2021-07-03

Variant appearance in text: p53: R175A
PubMed Link: 34283062
Variant Present in the following documents:
  • Main text
  • cancers-13-03344.pdf
View BVdb publication page



Differential chromatin accessibility landscape of gain-of-function mutant p53 tumours.

Bmc Cancer
Dhaka, Bhavya B; Sabarinathan, Radhakrishnan R
Publication Date: 2021-06-05

Variant appearance in text: p53: R175A
PubMed Link: 34090364
Variant Present in the following documents:
  • Main text
  • 12885_2021_Article_8362.pdf
View BVdb publication page



Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.

Cell Death And Differentiation
Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T
Publication Date: 2021-05

Variant appearance in text: p53: R175A
PubMed Link: 33257846
Variant Present in the following documents:
  • 41418_2020_672_MOESM1_ESM.pdf
View BVdb publication page



Identification and functional characterization of new missense SNPs in the coding region of the TP53 gene.

Cell Death And Differentiation
Doffe, Flora F; Carbonnier, Vincent V; Tissier, Manon M; Leroy, Bernard B; Martins, Isabelle I; Mattsson, Johanna S M JSM; Micke, Patrick P; Pavlova, Sarka S; Pospisilova, Sarka S; Smardova, Jana J; Joerger, Andreas C AC; Wiman, Klas G KG; Kroemer, Guido G; Soussi, Thierry T
Publication Date: 2021-05

Variant appearance in text: p53: R175A
PubMed Link: 33257846
Variant Present in the following documents:
  • 41418_2020_672_MOESM1_ESM.pdf
View BVdb publication page



Interactions of p53 with poly(ADP-ribose) and DNA induce distinct changes in protein structure as revealed by ATR-FTIR spectroscopy.

Nucleic Acids Research
Krüger, Annika A; Stier, Anna A; Fischbach, Arthur A; Bürkle, Alexander A; Hauser, Karin K; Mangerich, Aswin A
Publication Date: 2019-05-21

Variant appearance in text: p53: R175A
PubMed Link: 30892621
Variant Present in the following documents:
  • Main text
  • gkz175.pdf
View BVdb publication page



UBE3A regulates the transcription of IRF, an antiviral immunity.

Human Molecular Genetics
Furumai, Ryohei R; Tamada, Kota K; Liu, Xiaoxi X; Takumi, Toru T
Publication Date: 2019-06-15

Variant appearance in text: p53: R175A
PubMed Link: 30690483
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular chaperones in the acquisition of cancer cell chemoresistance with mutated TP53 and MDM2 up-regulation.

Oncotarget
Tracz-Gaszewska, Zuzanna Z; Klimczak, Marta M; Biecek, Przemyslaw P; Herok, Marcin M; Kosinski, Marcin M; Olszewski, Maciej B MB; Czerwińska, Patrycja P; Wiech, Milena M; Wiznerowicz, Maciej M; Zylicz, Alicja A; Zylicz, Maciej M; Wawrzynow, Bartosz B
Publication Date: 2017-10-10

Variant appearance in text: p53: R175A
PubMed Link: 29137250
Variant Present in the following documents:
  • Main text
  • oncotarget-08-82123.pdf
View BVdb publication page