Publications:

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Ether phospholipids are required for mitochondrial reactive oxygen species homeostasis.

Nature Communications

Chen, Ziheng Z; Ho, I-Lin IL; Soeung, Melinda M; Yen, Er-Yen EY; Liu, Jintan J; Yan, Liang L; Rose, Johnathon L JL; Srinivasan, Sanjana S; Jiang, Shan S; Edward Chang, Q Q; Feng, Ningping N; Gay, Jason P JP; Wang, Qi Q; Wang, Jing J; Lorenzi, Philip L PL; Veillon, Lucas J LJ; Wei, Bo B; Weinstein, John N JN; Deem, Angela K AK; Gao, Sisi S; Genovese, Giannicola G; Viale, Andrea A; Yao, Wantong W; Lyssiotis, Costas A CA; Marszalek, Joseph R JR; Draetta, Giulio F GF; Ying, Haoqiang H

Publication Date: 2023-04-17

Variant appearance in text: TP53: F134L

PubMed Link: 37069167

Variant Present in the following documents:

• 41467_2023_37924_MOESM1_ESM.pdf

View BVdb publication page

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RBFOX2 modulates a metastatic signature of alternative splicing in pancreatic cancer.

Nature

Jbara, Amina A; Lin, Kuan-Ting KT; Stossel, Chani C; Siegfried, Zahava Z; Shqerat, Haya H; Amar-Schwartz, Adi A; Elyada, Ela E; Mogilevsky, Maxim M; Raitses-Gurevich, Maria M; Johnson, Jared L JL; Yaron, Tomer M TM; Ovadia, Ofek O; Jang, Gun Ho GH; Danan-Gotthold, Miri M; Cantley, Lewis C LC; Levanon, Erez Y EY; Gallinger, Steven S; Krainer, Adrian R AR; Golan, Talia T; Karni, Rotem R

Publication Date: 2023-03-22

Variant appearance in text: TP53: F134L

PubMed Link: 36949200

Variant Present in the following documents:

• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 3
• 41586_2023_5820_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 3
• Table_2.xlsx, sheet 2

View BVdb publication page

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: TP53: F134L

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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NF1 loss of function as an alternative initiating event in pancreatic ductal adenocarcinoma.

Cell Reports

Ramakrishnan, Gopalakrishnan G; Parajuli, Parash P; Singh, Pura P; Friend, Creighton C; Hurwitz, Eric E; Prunier, Celine C; Razzaque, Mohammed S MS; Xu, Keli K; Atfi, Azeddine A

Publication Date: 2022-11-08

Variant appearance in text: TP53: F134L

PubMed Link: 36351408

Variant Present in the following documents:

• NIHMS1848910-supplement-2.xlsx, sheet 3
• NIHMS1848910-supplement-2.xlsx, sheet 2

View BVdb publication page

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Pirtobrutinib Targets BTK C481S in Ibrutinib-Resistant CLL but Second-Site BTK Mutations Lead to Resistance.

Blood Advances

Naeem, Aishath A; Utro, Filippo F; Wang, Qing Q; Cha, Justin J; Vihinen, Mauno M; Martindale, Stephen P SP; Zhou, Yinglu Y; Ren, Yue Y; Tyekucheva, Svitlana S; Kim, Annette S AS; Fernandes, Stacey M SM; Saksena, Gordon G; Rhrissorrakrai, Kahn K; Levovitz, Chaya C; Danysh, Brian P BP; Slowik, Kara K; Jacobs, Raquel A RA; Davids, Matthew S MS; Lederer, James A JA; Zain, Rula R; Smith, C I Edvard CIE; Leshchiner, Ignaty I; Parida, Laxmi L; Getz, Gad G; Brown, Jennifer R JR

Publication Date: 2022-10-26

Variant appearance in text: TP53: F134L

PubMed Link: 36287227

Variant Present in the following documents:

• BLOODA_ADV-2022-008447-mmc1.xlsx, sheet 4

View BVdb publication page

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Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology

Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W

Publication Date: 2022

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 36238300

Variant Present in the following documents:

• Table_1.xlsx, sheet 4

View BVdb publication page

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Molecular Profile Changes in Patients with Castrate-Resistant Prostate Cancer Pre- and Post-Abiraterone/Prednisone Treatment.

Molecular Cancer Research : Mcr

Sicotte, Hugues H; Kalari, Krishna R KR; Qin, Sisi S; Dehm, Scott M SM; Bhargava, Vipul V; Gormley, Michael M; Tan, Winston W; Sinnwell, Jason P JP; Hillman, David W DW; Li, Ying Y; Vedell, Peter T PT; Carlson, Rachel E RE; Bryce, Alan H AH; Jimenez, Raphael E RE; Weinshilboum, Richard M RM; Kohli, Manish M; Wang, Liewei L

Publication Date: 2022-12-02

Variant appearance in text: TP53: F134L

PubMed Link: 36135372

Variant Present in the following documents:

• mcr-22-0099_supplementary_tables_1-41_suppst1-41.xlsx, sheet 10

View BVdb publication page

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EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine

Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W

Publication Date: 2022-09-19

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 36123678

Variant Present in the following documents:

• 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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CTCF DNA-binding domain undergoes dynamic and selective protein-protein interactions.

Iscience

Zhou, Rong R; Tian, Kai K; Huang, Jie J; Duan, Wenjia W; Fu, Hongye H; Feng, Ying Y; Wang, Hui H; Jiang, Yongpeng Y; Li, Yuanjun Y; Wang, Rui R; Hu, Jiazhi J; Ma, Hanhui H; Qi, Zhi Z; Ji, Xiong X

Publication Date: 2022-09-16

Variant appearance in text: p53: F134L

PubMed Link: 36117989

Variant Present in the following documents:

• mmc4.xlsx, sheet 1

View BVdb publication page

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Integrated cohort of esophageal squamous cell cancer reveals genomic features underlying clinical characteristics.

Nature Communications

Li, Minghao M; Zhang, Zicheng Z; Wang, Qianrong Q; Yi, Yan Y; Li, Baosheng B

Publication Date: 2022-09-07

Variant appearance in text: TP53: F134L

PubMed Link: 36071046

Variant Present in the following documents:

• 41467_2022_32962_MOESM15_ESM.xlsx, sheet 22

View BVdb publication page

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Landscape of somatic alterations in large-scale solid tumors from an Asian population.

Nature Communications

Wu, Liqun L; Yao, Herui H; Chen, Hui H; Wang, Aodi A; Guo, Kun K; Gou, Wenli W; Yu, Yanfei Y; Li, Xiang X; Yao, Ming M; Yuan, Shaohua S; Pang, Fei F; Hu, Jinwei J; Chen, Lijuan L; Liu, Wenjin W; Yao, Jicheng J; Zhang, Shuirong S; Dong, Xiaowei X; Wang, Weifeng W; Hu, Jing J; Ling, Qi Q; Ding, Songming S; Wei, Yan Y; Li, Qiang Q; Cao, Weichun W; Wang, Shuang S; Di, Yang Y; Feng, Feiling F; Zhao, Gang G; Zhang, Jian J; Huang, Ling L; Xu, Jia J; Yan, Wangjun W; Tong, Zhongsheng Z; Jiang, Da D; Ji, Tao T; Li, Qiao Q; Xu, Ling L; He, Huiying H; Shang, Liang L; Liu, Jin J; Wang, Kefeng K; Wu, Duoguang D; Shen, Jingnan J; Liu, Ye Y; Zhang, Ting T; Liang, Chaojie C; Wang, Yusheng Y; Shang, Yanhong Y; Guo, Jianji J; Liang, Guanbiao G; Xu, Shifeng S; Liu, Junfeng J; Wang, Kai K; Wang, Minghui M

Publication Date: 2022-07-23

Variant appearance in text: TP53: F134L

PubMed Link: 35871175

Variant Present in the following documents:

• 41467_2022_31780_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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Clinical genomic profiling in the management of patients with soft tissue and bone sarcoma.

Nature Communications

Gounder, Mrinal M MM; Agaram, Narasimhan P NP; Trabucco, Sally E SE; Robinson, Victoria V; Ferraro, Richard A RA; Millis, Sherri Z SZ; Krishnan, Anita A; Lee, Jessica J; Attia, Steven S; Abida, Wassim W; Drilon, Alexander A; Chi, Ping P; Angelo, Sandra P D' SP; Dickson, Mark A MA; Keohan, Mary Lou ML; Kelly, Ciara M CM; Agulnik, Mark M; Chawla, Sant P SP; Choy, Edwin E; Chugh, Rashmi R; Meyer, Christian F CF; Myer, Parvathi A PA; Moore, Jessica L JL; Okimoto, Ross A RA; Pollock, Raphael E RE; Ravi, Vinod V; Singh, Arun S AS; Somaiah, Neeta N; Wagner, Andrew J AJ; Healey, John H JH; Frampton, Garrett M GM; Venstrom, Jeffrey M JM; Ross, Jeffrey S JS; Ladanyi, Marc M; Singer, Samuel S; Brennan, Murray F MF; Schwartz, Gary K GK; Lazar, Alexander J AJ; Thomas, David M DM; Maki, Robert G RG; Tap, William D WD; Ali, Siraj M SM; Jin, Dexter X DX

Publication Date: 2022-06-15

Variant appearance in text: TP53: F134L

PubMed Link: 35705558

Variant Present in the following documents:

• 41467_2022_30496_MOESM2_ESM.xls, sheet 1

View BVdb publication page

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A stop-gain mutation in GXYLT1 promotes metastasis of colorectal cancer via the MAPK pathway.

Cell Death & Disease

Peng, Lin L; Zhao, Min M; Liu, Tianqi T; Chen, Jiangbo J; Gao, Pin P; Chen, Lei L; Xing, Pu P; Wang, Zaozao Z; Di, Jiabo J; Xu, Qiang Q; Qu, Hong H; Jiang, Beihai B; Su, Xiangqian X

Publication Date: 2022-04-22

Variant appearance in text: TP53: F134L

PubMed Link: 35459861

Variant Present in the following documents:

• 41419_2022_4844_MOESM4_ESM.xlsx, sheet 3

View BVdb publication page

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Clinical and genomic features of Chinese lung cancer patients with germline mutations.

Nature Communications

Peng, Wenying W; Li, Bin B; Li, Jin J; Chang, Lianpeng L; Bai, Jing J; Yi, Yuting Y; Chen, Rongrong R; Zhang, Yanyan Y; Chen, Chen C; Pu, Xingxiang X; Jiang, Meilin M; Li, Jia J; Zhong, Rui R; Xu, Fang F; Chen, Bolin B; Xu, Li L; Wang, Ning N; Huan, Jiaojiao J; Dai, Pingping P; Guan, Yanfang Y; Yang, Ling L; Xia, Xuefeng X; Yi, Xin X; Wang, Jiayin J; Yu, Fenglei F; Wu, Lin L

Publication Date: 2022-03-10

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 35273153

Variant Present in the following documents:

• 41467_2022_28840_MOESM7_ESM.xlsx, sheet 1

View BVdb publication page

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Epidemiology and Molecular Profile of Mucosal Melanoma: A Population-Based Study in Southern Europe.

Cancers

Carbó-Bagué, Anna A; Rubió-Casadevall, Jordi J; Puigdemont, Montserrat M; Sanvisens, Arantza A; Oliveras, Glòria G; Coll, Mònica M; Del Olmo, Bernat B; Perez-Bueno, Ferran F; Marcos-Gragera, Rafael R

Publication Date: 2022-02-03

Variant appearance in text: TP53: F134L

PubMed Link: 35159047

Variant Present in the following documents:

• Main text
• cancers-14-00780.pdf

View BVdb publication page

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Epidemiology and Molecular Profile of Mucosal Melanoma: A Population-Based Study in Southern Europe.

Cancers

Carbó-Bagué, Anna A; Rubió-Casadevall, Jordi J; Puigdemont, Montserrat M; Sanvisens, Arantza A; Oliveras, Glòria G; Coll, Mònica M; Del Olmo, Bernat B; Perez-Bueno, Ferran F; Marcos-Gragera, Rafael R

Publication Date: 2022-02-03

Variant appearance in text: TP53: F134L

PubMed Link: 35159047

Variant Present in the following documents:

• Main text
• cancers-14-00780.pdf

View BVdb publication page

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Precision cancer genome testing needs proficiency testing involving all stakeholders.

Scientific Reports

Maekawa, Masato M; Taniguchi, Terumi T; Nishio, Kazuto K; Sakai, Kazuko K; Matsushita, Kazuyuki K; Nakatani, Kaname K; Ishige, Takayuki T; Ikejiri, Makoto M; Nishihara, Hiroshi H; Sunami, Kuniko K; Yatabe, Yasushi Y; Hatanaka, Kanako C KC; Hatanaka, Yutaka Y; Yamamoto, Yoshihiro Y; Fukuyama, Keita K; Oda, Shinya S; Saito, Kayoko K; Yokomura, Mamoru M; Kubo, Yuji Y; Sato, Hiroko H; Tanaka, Yoshinori Y; Fuchioka, Misa M; Yamasaki, Tadashi T; Matsuda, Koichiro K; Kurachi, Kiyotaka K; Funai, Kazuhiro K; Baba, Satoshi S; Iwaizumi, Moriya M

Publication Date: 2022-01-27

Variant appearance in text: TP53: 402T>G; Phe134Leu

PubMed Link: 35087199

Variant Present in the following documents:

• 41598_2022_5589_MOESM1_ESM.pdf

View BVdb publication page

---

Precision cancer genome testing needs proficiency testing involving all stakeholders.

Scientific Reports

Maekawa, Masato M; Taniguchi, Terumi T; Nishio, Kazuto K; Sakai, Kazuko K; Matsushita, Kazuyuki K; Nakatani, Kaname K; Ishige, Takayuki T; Ikejiri, Makoto M; Nishihara, Hiroshi H; Sunami, Kuniko K; Yatabe, Yasushi Y; Hatanaka, Kanako C KC; Hatanaka, Yutaka Y; Yamamoto, Yoshihiro Y; Fukuyama, Keita K; Oda, Shinya S; Saito, Kayoko K; Yokomura, Mamoru M; Kubo, Yuji Y; Sato, Hiroko H; Tanaka, Yoshinori Y; Fuchioka, Misa M; Yamasaki, Tadashi T; Matsuda, Koichiro K; Kurachi, Kiyotaka K; Funai, Kazuhiro K; Baba, Satoshi S; Iwaizumi, Moriya M

Publication Date: 2022-01-27

Variant appearance in text: TP53: 402T>G; Phe134Leu

PubMed Link: 35087199

Variant Present in the following documents:

• 41598_2022_5589_MOESM1_ESM.pdf

View BVdb publication page

---

The dominant TP53 hotspot mutation in -mutant astrocytoma, R273C, has distinctive pathologic features and sex-specific prognostic implications.

Neuro-Oncology Advances

Marker, Daniel F DF; Agnihotri, Sameer S; Amankulor, Nduka N; Murdoch, Geoffrey H GH; Pearce, Thomas M TM

Publication Date: 2022

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 35047821

Variant Present in the following documents:

• vdab182_suppl_supplementary_table_s1.xlsx, sheet 1
• vdab182_suppl_supplementary_table_s1.xlsx, sheet 3

View BVdb publication page

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Influence of TP53 Mutation on Survival of Diffuse Large B-Cell Lymphoma in the CAR T-Cell Era.

Cancers

Porpaczy, Edit E; Wohlfarth, Philipp P; Königsbrügge, Oliver O; Rabitsch, Werner W; Skrabs, Cathrin C; Staber, Philipp P; Worel, Nina N; Müllauer, Leonhard L; Simonitsch-Klupp, Ingrid I; Kornauth, Christoph C; Rohrbeck, Johannes J; Jaeger, Ulrich U; Schiefer, Ana-Iris AI

Publication Date: 2021-11-09

Variant appearance in text: TP53: F134L

PubMed Link: 34830747

Variant Present in the following documents:

• Main text

View BVdb publication page

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Prognostic value of BCL2 and TP53 genetic alterations for diffuse large B-cell lymphoma patients treated with R-CHOP.

Cancer Biology & Medicine

Qin, Yan Y; Chen, Haizhu H; Liu, Peng P; Zhang, Changgong C; Yang, Jianliang J; Gui, Lin L; He, Xiaohui X; Zhou, Liqiang L; Zhou, Shengyu S; Jiang, Shiyu S; Jiang, Hongxin H; Shi, Yuankai Y

Publication Date: 2021-11-23

Variant appearance in text: TP53: F134L

PubMed Link: 34806851

Variant Present in the following documents:

• cbm-19-893-s001.pdf

View BVdb publication page

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Structural and Drug Targeting Insights on Mutant p53.

Cancers

Gomes, Ana Sara AS; Ramos, Helena H; Inga, Alberto A; Sousa, Emília E; Saraiva, Lucília L

Publication Date: 2021-07-03

Variant appearance in text: p53: F134L

PubMed Link: 34283062

Variant Present in the following documents:

• Main text
• cancers-13-03344.pdf

View BVdb publication page

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A computational and structural analysis of germline and somatic variants affecting the DDR mechanism, and their impact on human diseases.

Scientific Reports

Magraner-Pardo, Lorena L; Laskowski, Roman A RA; Pons, Tirso T; Thornton, Janet M JM

Publication Date: 2021-07-12

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 34253785

Variant Present in the following documents:

• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 9
• 41598_2021_93715_MOESM2_ESM.xlsx, sheet 10

View BVdb publication page

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Improvement of Neoantigen Identification Through Convolution Neural Network.

Frontiers In Immunology

Hao, Qing Q; Wei, Ping P; Shu, Yang Y; Zhang, Yi-Guan YG; Xu, Heng H; Zhao, Jun-Ning JN

Publication Date: 2021

Variant appearance in text: TP53: F134L

PubMed Link: 34113354

Variant Present in the following documents:

• Table_1.xlsx, sheet 31
• Table_1.xlsx, sheet 26
• Table_1.xlsx, sheet 27
• Table_1.xlsx, sheet 8

View BVdb publication page

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Occurence of RAS reversion in metastatic colorectal cancer patients treated with bevacizumab.

Oncotarget

Epistolio, Samantha S; Cefalì, Marco M; Spina, Paolo P; Molinari, Francesca F; Movilia, Alessandra A; Cergnul, Massimiliano M; Mazzucchelli, Luca L; De Dosso, Sara S; Frattini, Milo M; Saletti, Piercarlo P

Publication Date: 2021-05-25

Variant appearance in text: TP53: F134L

PubMed Link: 34084279

Variant Present in the following documents:

• Main text
• oncotarget-12-1046.pdf

View BVdb publication page

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: TP53: F134L

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Comprehensive omic characterization of breast cancer in Mexican-Hispanic women.

Nature Communications

Romero-Cordoba, Sandra L SL; Salido-Guadarrama, Ivan I; Rebollar-Vega, Rosa R; Bautista-Piña, Veronica V; Dominguez-Reyes, Carlos C; Tenorio-Torres, Alberto A; Villegas-Carlos, Felipe F; Fernández-López, Juan C JC; Uribe-Figueroa, Laura L; Alfaro-Ruiz, Luis L; Hidalgo-Miranda, Alfredo A

Publication Date: 2021-04-14

Variant appearance in text: TP53: F134L

PubMed Link: 33854067

Variant Present in the following documents:

• 41467_2021_22478_MOESM8_ESM.xlsx, sheet 9

View BVdb publication page

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Oncogenic KRAS Recruits an Expansive Transcriptional Network through Mutant p53 to Drive Pancreatic Cancer Metastasis.

Cancer Discovery

Kim, Michael P MP; Li, Xinqun X; Deng, Jenying J; Zhang, Yun Y; Dai, Bingbing B; Allton, Kendra L KL; Hughes, Tara G TG; Siangco, Christian C; Augustine, Jithesh J JJ; Kang, Ya'an Y; McDaniel, Joy M JM; Xiong, Shunbin S; Koay, Eugene J EJ; McAllister, Florencia F; Bristow, Christopher A CA; Heffernan, Timothy P TP; Maitra, Anirban A; Liu, Bin B; Barton, Michelle C MC; Wasylishen, Amanda R AR; Fleming, Jason B JB; Lozano, Guillermina G

Publication Date: 2021-08

Variant appearance in text: p53: F134L

PubMed Link: 33839689

Variant Present in the following documents:

• Main text

View BVdb publication page

---

Mutation profile and immunoscore signature in thymic carcinomas: An exploratory study and review of the literature.

Thoracic Cancer

Asselta, Rosanna R; Di Tommaso, Luca L; Perrino, Matteo M; Destro, Annarita A; Giordano, Laura L; Cardamone, Giulia G; Rubino, Luca L; Santoro, Armando A; Duga, Stefano S; Zucali, Paolo Andrea PA

Publication Date: 2021-05

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 33704917

Variant Present in the following documents:

• TCA-12-1271-s003.xls, sheet 1

View BVdb publication page

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Evolutionary action score identifies a subset of TP53 mutated myelodysplastic syndrome with favorable prognosis.

Blood Cancer Journal

Kanagal-Shamanna, Rashmi R; Montalban-Bravo, Guillermo G; Katsonis, Panagiotis P; Sasaki, Koji K; Class, Caleb A CA; Jabbour, Elias E; Sallman, David D; Hunter, Anthony Michael AM; Benton, Christopher C; Chien, Kelly S KS; Luthra, Rajyalakshmi R; Bueso-Ramos, Carlos E CE; Kadia, Tapan T; Andreeff, Michael M; Komrokji, Rami S RS; Al Ali, Najla H NH; Short, Nicholas N; Daver, Naval N; Routbort, Mark J MJ; Khoury, Joseph D JD; Patel, Keyur K; Ganan-Gomez, Irene I; Wei, Yue Y; Borthakur, Gautam G; Ravandi, Farhad F; Do, Kim-Anh KA; Soltysiak, Kelly A KA; Lichtarge, Olivier O; Medeiros, L Jeffrey LJ; Kantarjian, Hagop H; Garcia-Manero, Guillermo G

Publication Date: 2021-03-06

Variant appearance in text: TP53: F134L

PubMed Link: 33677472

Variant Present in the following documents:

• Main text

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1
• 41467_2020_20162_MOESM9_ESM.xlsx, sheet 1

View BVdb publication page

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: TP53: F134L

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s002.xlsx, sheet 1
• CAM4-10-53-s004.xlsx, sheet 1
• CAM4-10-53-s003.xlsx, sheet 1

View BVdb publication page

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Genomic and transcriptomic alterations associated with drug vulnerabilities and prognosis in adenocarcinoma at the gastroesophageal junction.

Nature Communications

Lin, Yuan Y; Luo, Yingying Y; Sun, Yanxia Y; Guo, Wenjia W; Zhao, Xuan X; Xi, Yiyi Y; Ma, Yuling Y; Shao, Mingming M; Tan, Wen W; Gao, Ge G; Wu, Chen C; Lin, Dongxin D

Publication Date: 2020-11-30

Variant appearance in text: TP53: F134L

PubMed Link: 33257699

Variant Present in the following documents:

• 41467_2020_19949_MOESM8_ESM.xlsx, sheet 1

View BVdb publication page

---

Blood functional assay for rapid clinical interpretation of germline TP53 variants.

Journal Of Medical Genetics

Raad, Sabine S; Rolain, Marion M; Coutant, Sophie S; Derambure, Céline C; Lanos, Raphael R; Charbonnier, Françoise F; Bou, Jacqueline J; Bouvignies, Emilie E; Lienard, Gwendoline G; Vasseur, Stéphanie S; Farrell, Michael M; Ingster, Olivier O; Baert Desurmont, Stéphanie S; Kasper, Edwige E; Bougeard, Gaëlle G; Frébourg, Thierry T; Tournier, Isabelle I

Publication Date: 2021-12

Variant appearance in text: p53: 402T>G

PubMed Link: 33051313

Variant Present in the following documents:

• Main text

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Blood functional assay for rapid clinical interpretation of germline TP53 variants.

Journal Of Medical Genetics

Raad, Sabine S; Rolain, Marion M; Coutant, Sophie S; Derambure, Céline C; Lanos, Raphael R; Charbonnier, Françoise F; Bou, Jacqueline J; Bouvignies, Emilie E; Lienard, Gwendoline G; Vasseur, Stéphanie S; Farrell, Michael M; Ingster, Olivier O; Baert Desurmont, Stéphanie S; Kasper, Edwige E; Bougeard, Gaëlle G; Frébourg, Thierry T; Tournier, Isabelle I

Publication Date: 2021-12

Variant appearance in text: p53: 402T>G

PubMed Link: 33051313

Variant Present in the following documents:

• Main text

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Specific TP53 subtype as biomarker for immune checkpoint inhibitors in lung adenocarcinoma.

Ebiomedicine

Sun, Hao H; Liu, Si-Yang SY; Zhou, Jia-Ying JY; Xu, Jin-Tian JT; Zhang, Huang-Kai HK; Yan, Hong-Hong HH; Huan, Jiao-Jiao JJ; Dai, Ping-Ping PP; Xu, Chong-Rui CR; Su, Jian J; Guan, Yan-Fang YF; Yi, Xin X; Yu, Rong-Shan RS; Zhong, Wen-Zhao WZ; Wu, Yi-Long YL

Publication Date: 2020-10

Variant appearance in text: TP53: 402T>G; Phe134Leu

PubMed Link: 32927274

Variant Present in the following documents:

• mmc2.xlsx, sheet 1

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The mutational landscape of the SCAN-B real-world primary breast cancer transcriptome.

Embo Molecular Medicine

Brueffer, Christian C; Gladchuk, Sergii S; Winter, Christof C; Vallon-Christersson, Johan J; Hegardt, Cecilia C; Häkkinen, Jari J; George, Anthony M AM; Chen, Yilun Y; Ehinger, Anna A; Larsson, Christer C; Loman, Niklas N; Malmberg, Martin M; Rydén, Lisa L; Borg, Åke Å; Saal, Lao H LH

Publication Date: 2020-10-07

Variant appearance in text: TP53: F134L

PubMed Link: 32926574

Variant Present in the following documents:

• Main text
• EMMM-12-e12118.pdf

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A risk-associated Active transcriptome phenotype expressed by histologically normal human breast tissue and linked to a pro-tumorigenic adipocyte population.

Breast Cancer Research : Bcr

Kang, Taekyu T; Yau, Christina C; Wong, Christopher K CK; Sanborn, John Z JZ; Newton, Yulia Y; Vaske, Charlie C; Benz, Stephen C SC; Krings, Gregor G; Camarda, Roman R; Henry, Jill E JE; Stuart, Josh J; Powell, Mark M; Benz, Christopher C CC

Publication Date: 2020-07-31

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 32736587

Variant Present in the following documents:

• 13058_2020_1322_MOESM3_ESM.xlsx, sheet 1

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Novel bioinformatic classification system for genetic signatures identification in diffuse large B-cell lymphoma.

Bmc Cancer

Zhang, Wei W; Yang, Li L; Guan, Yu' Qi YQ; Shen, Ke' Feng KF; Zhang, Mei' Lan ML; Cai, Hao' Dong HD; Wang, Jia' Chen JC; Wang, Ying Y; Huang, Liang L; Cao, Yang Y; Wang, Na N; Tan, Xiao' Hong XH; Young, Ken He KH; Xiao, Min M; Zhou, Jian' Feng JF

Publication Date: 2020-07-31

Variant appearance in text: TP53: 402T>G; Phe134Leu

PubMed Link: 32736575

Variant Present in the following documents:

• 12885_2020_7198_MOESM5_ESM.xlsx, sheet 1

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Tumorigenic p53 mutants undergo common structural disruptions including conversion to α-sheet structure.

Protein Science : A Publication Of The Protein Society

Bromley, Dennis D; Daggett, Valerie V

Publication Date: 2020-09

Variant appearance in text: p53: F134L

PubMed Link: 32715544

Variant Present in the following documents:

• Main text

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Defining relative mutational difficulty to understand cancer formation.

Cell Discovery

Shan, Lin L; Yu, Jiao J; He, Zhengjin Z; Chen, Shishuang S; Liu, Mingxian M; Ding, Hongyu H; Xu, Liang L; Zhao, Jie J; Yang, Ailing A; Jiang, Hai H

Publication Date: 2020

Variant appearance in text: p53: F134L

PubMed Link: 32704382

Variant Present in the following documents:

• 41421_2020_177_MOESM7_ESM.xlsx, sheet 1

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Malignant teratoid tumor of the thyroid gland: an aggressive primitive multiphenotypic malignancy showing organotypical elements and frequent DICER1 alterations-is the term "thyroblastoma" more appropriate?

Virchows Archiv : An International Journal Of Pathology

Agaimy, Abbas A; Witkowski, Leora L; Stoehr, Robert R; Cuenca, Joseph Christopher Castillo JCC; González-Muller, Carlos Alberto CA; Brütting, Alfred A; Bährle, Markus M; Mantsopoulos, Konstantinos K; Amin, Randa M S RMS; Hartmann, Arndt A; Metzler, Markus M; Amr, Samir S SS; Foulkes, William D WD; Sobrinho-Simões, Manuel M; Eloy, Catarina C

Publication Date: 2020-12

Variant appearance in text: TP53: Phe134Leu

PubMed Link: 32507920

Variant Present in the following documents:

• Main text
• 428_2020_Article_2853.pdf

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Transcriptional profiling reveals a subset of human breast tumors that retain wt TP53 but display mutant p53-associated features.

Molecular Oncology

Benor, Gal G; Fuks, Garold G; Chin, Suet-Feung SF; Rueda, Oscar M OM; Mukherjee, Saptaparna S; Arandkar, Sharathchandra S; Aylon, Yael Y; Caldas, Carlos C; Domany, Eytan E; Oren, Moshe M

Publication Date: 2020-08

Variant appearance in text: TP53: F134L

PubMed Link: 32484602

Variant Present in the following documents:

• MOL2-14-1640-s002.pdf

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Comprehensive Genomic Profiling of Rare Tumors: Routes to Targeted Therapies.

Frontiers In Oncology

Wang, Shuhang S; Chen, Rongrong R; Tang, Yu Y; Yu, Yue Y; Fang, Yuan Y; Huang, Huiyao H; Wu, Dawei D; Fang, Hong H; Bai, Ying Y; Sun, Chao C; Yu, Anqi A; Fan, Qi Q; Gu, Dejian D; Yi, Xin X; Li, Ning N

Publication Date: 2020

Variant appearance in text: TP53: 402T>G; F134L

PubMed Link: 32373528

Variant Present in the following documents:

• Table_6.xlsx, sheet 1

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TGPred: a tumor gene prediction webserver for analyzing structural and functional impacts of variants.

Journal Of Molecular Cell Biology

Liu, Jixiang J; Liu, Wei W; Li, Xue-Ling XL; Li, Quanxue Q; Dai, Wentao W; Li, Yuan-Yuan YY

Publication Date: 2020-07-01

Variant appearance in text: p53: F134L

PubMed Link: 32246141

Variant Present in the following documents:

• Main text
• supplementary_material_mjaa007.pdf
• mjaa007.pdf

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Prognosis, Biology, and Targeting of TP53 Dysregulation in Multiple Myeloma.

Cells

Flynt, Erin E; Bisht, Kamlesh K; Sridharan, Vinidhra V; Ortiz, María M; Towfic, Fadi F; Thakurta, Anjan A

Publication Date: 2020-01-24

Variant appearance in text: TP53: F134L

PubMed Link: 31991614

Variant Present in the following documents:

• Main text

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TP53 structural variants in metastatic prostatic carcinoma.

Plos One

Sirohi, Deepika D; Devine, Patrick P; Grenert, James P JP; van Ziffle, Jessica J; Simko, Jeffry P JP; Stohr, Bradley A BA

Publication Date: 2019

Variant appearance in text: TP53: F134L

PubMed Link: 31216325

Variant Present in the following documents:

• Main text

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Benefit from anti-EGFRs in RAS and BRAF wild-type metastatic transverse colon cancer: a clinical and molecular proof of concept study.

Esmo Open

Cremolini, Chiara C; Benelli, Matteo M; Fontana, Elisa E; Pagani, Filippo F; Rossini, Daniele D; Fucà, Giovanni G; Busico, Adele A; Conca, Elena E; Di Donato, Samantha S; Loupakis, Fotios F; Schirripa, Marta M; Lonardi, Sara S; Borelli, Beatrice B; Ongaro, Elena E; Eason, Katherine K; Morano, Federica F; Casagrande, Mariaelena M; Fassan, Matteo M; Sadanandam, Anguraj A; de Braud, Filippo F; Falcone, Alfredo A; Pietrantonio, Filippo F

Publication Date: 2019

Variant appearance in text: TP53: F134L

PubMed Link: 30962964

Variant Present in the following documents:

• Main text
• esmoopen-2019-000489.pdf

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Ibrutinib therapy downregulates AID enzyme and proliferative fractions in chronic lymphocytic leukemia.

Blood

Morande, Pablo Elías PE; Sivina, Mariela M; Uriepero, Angimar A; Seija, Noé N; Berca, Catalina C; Fresia, Pablo P; Landoni, Ana Inés AI; Di Noia, Javier M JM; Burger, Jan A JA; Oppezzo, Pablo P

Publication Date: 2019-05-09

Variant appearance in text: TP53: 402T>G

PubMed Link: 30814061

Variant Present in the following documents:

• Main text

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Comparison of TCGA and GENIE genomic datasets for the detection of clinically actionable alterations in breast cancer.

Scientific Reports

Kaur, Pushpinder P; Porras, Tania B TB; Ring, Alexander A; Carpten, John D JD; Lang, Julie E JE

Publication Date: 2019-02-06

Variant appearance in text: TP53: F134L

PubMed Link: 30728399

Variant Present in the following documents:

• 41598_2018_37574_MOESM1_ESM.pdf

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Amplicon-based next-generation sequencing of plasma cell-free DNA for detection of driver and resistance mutations in advanced non-small cell lung cancer.

Annals Of Oncology : Official Journal Of The European Society For Medical Oncology

Guibert, N N; Hu, Y Y; Feeney, N N; Kuang, Y Y; Plagnol, V V; Jones, G G; Howarth, K K; Beeler, J F JF; Paweletz, C P CP; Oxnard, G R GR

Publication Date: 2018-04-01

Variant appearance in text: TP53: F134L

PubMed Link: 29325035

Variant Present in the following documents:

• Main text

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Somatic mutation driven codon transition bias in human cancer.

Scientific Reports

Son, Hyeonju H; Kang, Hyundeok H; Kim, Hyun Seok HS; Kim, Sangwoo S

Publication Date: 2017-10-27

Variant appearance in text: TP53: F134L

PubMed Link: 29079855

Variant Present in the following documents:

• Main text
• 41598_2017_14543_MOESM1_ESM.pdf
• 41598_2017_Article_14543.pdf

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A comprehensive analysis of coregulator recruitment, androgen receptor function and gene expression in prostate cancer.

Elife

Liu, Song S; Kumari, Sangeeta S; Hu, Qiang Q; Senapati, Dhirodatta D; Venkadakrishnan, Varadha Balaji VB; Wang, Dan D; DePriest, Adam D AD; Schlanger, Simon E SE; Ben-Salem, Salma S; Valenzuela, Malyn May MM; Willard, Belinda B; Mudambi, Shaila S; Swetzig, Wendy M WM; Das, Gokul M GM; Shourideh, Mojgan M; Koochekpour, Shahriah S; Falzarano, Sara Moscovita SM; Magi-Galluzzi, Cristina C; Yadav, Neelu N; Chen, Xiwei X; Lao, Changshi C; Wang, Jianmin J; Billaud, Jean-Noel JN; Heemers, Hannelore V HV

Publication Date: 2017-08-18

Variant appearance in text: p53: F134L

PubMed Link: 28826481

Variant Present in the following documents:

• Main text

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Low-burden TP53 mutations in chronic phase of myeloproliferative neoplasms: association with age, hydroxyurea administration, disease type and JAK2 mutational status.

Leukemia

Kubesova, B B; Pavlova, S S; Malcikova, J J; Kabathova, J J; Radova, L L; Tom, N N; Tichy, B B; Plevova, K K; Kantorova, B B; Fiedorova, K K; Slavikova, M M; Bystry, V V; Kissova, J J; Gisslinger, B B; Gisslinger, H H; Penka, M M; Mayer, J J; Kralovics, R R; Pospisilova, S S; Doubek, M M

Publication Date: 2018-02

Variant appearance in text: TP53: F134L

PubMed Link: 28744014

Variant Present in the following documents:

• Main text
• leu2017230a.pdf

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Presence of cancer-associated mutations in exhaled breath condensates of healthy individuals by next generation sequencing.

Oncotarget

Youssef, Omar O; Knuuttila, Aija A; Piirilä, Päivi P; Böhling, Tom T; Sarhadi, Virinder V; Knuutila, Sakari S

Publication Date: 2017-03-14

Variant appearance in text: TP53: F134L

PubMed Link: 28199989

Variant Present in the following documents:

• Main text
• oncotarget-08-18166.pdf

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