GAA c.2042C>A ;(p.P681H)

Variant ID: 17-78087018-C-A

NM_000152.3(GAA):c.2042C>A;(p.P681H)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


High-throughput screening of spike variants uncovers the key residues that alter the affinity and antigenicity of SARS-CoV-2.

Cell Discovery
Luo, Yufeng Y; Liu, Shuo S; Xue, Jiguo J; Yang, Ye Y; Zhao, Junxuan J; Sun, Ying Y; Wang, Bolun B; Yin, Shenyi S; Li, Juan J; Xia, Yuchao Y; Ge, Feixiang F; Dong, Jiqiao J; Guo, Lvze L; Ye, Buqing B; Huang, Weijin W; Wang, Youchun Y; Xi, Jianzhong Jeff JJ
Publication Date: 2023-04-11

Variant appearance in text: GAA: P681H
PubMed Link: 37041132
Variant Present in the following documents:
  • 41421_2023_534_MOESM1_ESM.pdf
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CRISPR-Cas13d effectively targets SARS-CoV-2 variants, including Delta and Omicron, and inhibits viral infection.

Medcomm
Liu, Zongzhi Z; Gao, Xiang X; Kan, Chuanwen C; Li, Lingyu L; Zhang, Yuan Y; Gao, Yibo Y; Zhang, Shengyuan S; Zhou, Liangji L; Zhao, Hui H; Li, Mingkun M; Zhang, Zheng Z; Sun, Yingli Y
Publication Date: 2023-02

Variant appearance in text: GAA: P681H
PubMed Link: 36744219
Variant Present in the following documents:
  • MCO2-4-e208.pdf
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Monitoring of the SARS-CoV-2 Omicron BA.1/BA.2 lineage transition in the Swedish population reveals increased viral RNA levels in BA.2 cases.

Med (New York, N.Y.)
Lentini, Antonio A; Pereira, Antonio A; Winqvist, Ola O; Reinius, Björn B
Publication Date: 2022-09-09

Variant appearance in text: GAA: P681H
PubMed Link: 35981541
Variant Present in the following documents:
  • mmc7.xlsx, sheet 1
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SARS-CoV-2 Variants in Paraguay: Detection and Surveillance with an Economical and Scalable Molecular Protocol.

Viruses
Martinez, Magaly M; Nguyen, Phuong-Vi PV; Su, Maxwell M; Cardozo, Fátima F; Valenzuela, Adriana A; Franco, Laura L; Galeano, María Eugenia ME; Rojas, Leticia Elizabeth LE; Díaz Acosta, Chyntia Carolina CC; Fernández, Jonás J; Ortiz, Joel J; Del Puerto, Florencia F; Mendoza, Laura L; Nara, Eva E; Rojas, Alejandra A; Waggoner, Jesse J JJ
Publication Date: 2022-04-22

Variant appearance in text: GAA: P681H
PubMed Link: 35632615
Variant Present in the following documents:
  • viruses-14-00873.pdf
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Genomic Surveillance of COVID-19 Variants With Language Models and Machine Learning.

Frontiers In Genetics
Nagpal, Sargun S; Pal, Ridam R; Ashima, ; Tyagi, Ananya A; Tripathi, Sadhana S; Nagori, Aditya A; Ahmad, Saad S; Mishra, Hara Prasad HP; Malhotra, Rishabh R; Kutum, Rintu R; Sethi, Tavpritesh T
Publication Date: 2022

Variant appearance in text: GAA: P681H
PubMed Link: 35464852
Variant Present in the following documents:
  • DataSheet1.pdf
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Establishment of a Rapid Typing Method for Coronavirus Disease 2019 Mutant Strains Based on PARMS Technology.

Micromachines
Gao, Lei L; Zu, Xiangyang X; Liu, Xiaohui X; Yu, Zhangqing Z; Du, Zhe Z; Hu, Zhigang Z; Xue, Yun Y
Publication Date: 2022-01-18

Variant appearance in text: GAA: P681H
PubMed Link: 35208270
Variant Present in the following documents:
  • micromachines-13-00145.pdf
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Emergency SARS-CoV-2 Variants of Concern: Novel Multiplex Real-Time RT-PCR Assay for Rapid Detection and Surveillance.

Microbiology Spectrum
Chung, Hsing-Yi HY; Jian, Ming-Jr MJ; Chang, Chih-Kai CK; Lin, Jung-Chung JC; Yeh, Kuo-Ming KM; Chen, Chien-Wen CW; Hsieh, Shan-Shan SS; Hung, Kuo-Sheng KS; Tang, Sheng-Hui SH; Perng, Cherng-Lih CL; Chang, Feng-Yee FY; Wang, Chih-Hung CH; Shang, Hung-Sheng HS
Publication Date: 2022-02-23

Variant appearance in text: GAA: P681H
PubMed Link: 35196812
Variant Present in the following documents:
  • Main text
  • spectrum.02513-21.pdf
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A SARS-CoV-2 Delta variant containing mutation in the probe binding region used for RT-qPCR test in Japan exhibited atypical PCR amplification and might induce false negative result.

Journal Of Infection And Chemotherapy : Official Journal Of The Japan Society Of Chemotherapy
Rajib, Samiul Alam SA; Ogi, Yasuhiro Y; Hossain, Md Belal MB; Ikeda, Terumasa T; Tanaka, Eiichi E; Kawaguchi, Tatsuya T; Satou, Yorifumi Y
Publication Date: 2022-05

Variant appearance in text: GAA: P681H
PubMed Link: 35144878
Variant Present in the following documents:
  • mmc2.xls, sheet 1
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Phylogenetic analysis of SARS-CoV-2 viruses circulating in the South American region: genetic relations and vaccine strain match.

Virus Research
Perbolianachis, Paula P; Ferla, Diego D; Arce, Rodrigo R; Ferreiro, Irene I; Costábile, Alicia A; Paz, Mercedes M; Simón, Diego D; Moreno, Pilar P; Cristina, Juan J
Publication Date: 2022-01-21

Variant appearance in text: GAA: P681H
PubMed Link: 35074431
Variant Present in the following documents:
  • Main text
View BVdb publication page



Phylogenetic analysis of SARS-CoV-2 viruses circulating in the South American region: Genetic relations and vaccine strain match.

Virus Research
Perbolianachis, Paula P; Ferla, Diego D; Arce, Rodrigo R; Ferreiro, Irene I; Costábile, Alicia A; Paz, Mercedes M; Simón, Diego D; Moreno, Pilar P; Cristina, Juan J
Publication Date: 2022-04-02

Variant appearance in text: GAA: P681H
PubMed Link: 35074431
Variant Present in the following documents:
  • Main text
View BVdb publication page



Tracking the circulating SARS-CoV-2 variant of concern in South Africa using wastewater-based epidemiology.

Scientific Reports
Johnson, Rabia R; Sharma, Jyoti R JR; Ramharack, Pritika P; Mangwana, Noluxabiso N; Kinnear, Craig C; Viraragavan, Amsha A; Glanzmann, Brigitte B; Louw, Johan J; Abdelatif, Nada N; Reddy, Tarylee T; Surujlal-Naicker, Swastika S; Nkambule, Sizwe S; Mahlangeni, Nomfundo N; Webster, Candice C; Mdhluli, Mongezi M; Gray, Glenda G; Mathee, Angela A; Preiser, Wolfgang W; Muller, Christo C; Street, Renee R
Publication Date: 2022-01-21

Variant appearance in text: GAA: P681H
PubMed Link: 35064174
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_5110.pdf
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Tracking the circulating SARS-CoV-2 variant of concern in South Africa using wastewater-based epidemiology.

Scientific Reports
Johnson, Rabia R; Sharma, Jyoti R JR; Ramharack, Pritika P; Mangwana, Noluxabiso N; Kinnear, Craig C; Viraragavan, Amsha A; Glanzmann, Brigitte B; Louw, Johan J; Abdelatif, Nada N; Reddy, Tarylee T; Surujlal-Naicker, Swastika S; Nkambule, Sizwe S; Mahlangeni, Nomfundo N; Webster, Candice C; Mdhluli, Mongezi M; Gray, Glenda G; Mathee, Angela A; Preiser, Wolfgang W; Muller, Christo C; Street, Renee R
Publication Date: 2022-01-21

Variant appearance in text: GAA: P681H
PubMed Link: 35064174
Variant Present in the following documents:
  • Main text
  • 41598_2022_Article_5110.pdf
View BVdb publication page



SARS-CoV-2 Omicron has extensive but incomplete escape of Pfizer BNT162b2 elicited neutralization and requires ACE2 for infection.

Medrxiv : The Preprint Server For Health Sciences
Cele, Sandile S; Jackson, Laurelle L; Khoury, David S DS; Khan, Khadija K; Moyo-Gwete, Thandeka T; Tegally, Houriiyah H; San, James Emmanuel JE; Cromer, Deborah D; Scheepers, Cathrine C; Amoako, Daniel D; Karim, Farina F; Bernstein, Mallory M; Lustig, Gila G; Archary, Derseree D; Smith, Muneerah M; Ganga, Yashica Y; Jule, Zesuliwe Z; Reedoy, Kajal K; Hwa, Shi-Hsia SH; Giandhari, Jennifer J; Blackburn, Jonathan M JM; Gosnell, Bernadett I BI; Abdool Karim, Salim S SS; Hanekom, Willem W; , ; , ; von Gottberg, Anne A; Bhiman, Jinal J; Lessells, Richard J RJ; Moosa, Mahomed-Yunus S MS; Davenport, Miles P MP; de Oliveira, Tulio T; Moore, Penny L PL; Sigal, Alex A
Publication Date: 2021-12-17

Variant appearance in text: GAA: P681H
PubMed Link: 34909788
Variant Present in the following documents:
  • nihpp-2021.12.08.21267417v3.pdf
  • NIHPP2021.12.08.21267417V3-supplement-1.pdf
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Temporal-Geographical Dispersion of SARS-CoV-2 Spike Glycoprotein Variant Lineages and Their Functional Prediction Using in Silico Approach.

Mbio
Boon, Siaw Shi SS; Xia, Chichao C; Wang, Maggie Haitian MH; Yip, Ka Lai KL; Luk, Ho Yin HY; Li, Sile S; Ng, Rita W Y RWY; Lai, Christopher K C CKC; Chan, Paul Kay Sheung PKS; Chen, Zigui Z
Publication Date: 2021-10-26

Variant appearance in text: GAA: P681H
PubMed Link: 34700382
Variant Present in the following documents:
  • mbio.02687-21.pdf
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Novel Nested-Seq Approach for SARS-CoV-2 Real-Time Epidemiology and In-Depth Mutational Profiling in Wastewater.

International Journal Of Molecular Sciences
Avgeris, Margaritis M; Adamopoulos, Panagiotis G PG; Galani, Aikaterini A; Xagorari, Marieta M; Gourgiotis, Dimitrios D; Trougakos, Ioannis P IP; Voulgaris, Nikolaos N; Dimopoulos, Meletios-Athanasios MA; Thomaidis, Nikolaos S NS; Scorilas, Andreas A
Publication Date: 2021-08-07

Variant appearance in text: GAA: P681H
PubMed Link: 34445204
Variant Present in the following documents:
  • Main text
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SARS-CoV-2 variant evolution in the United States: High accumulation of viral mutations over time likely through serial Founder Events and mutational bursts.

Plos One
Tasakis, Rafail Nikolaos RN; Samaras, Georgios G; Jamison, Anna A; Lee, Michelle M; Paulus, Alexandra A; Whitehouse, Gabrielle G; Verkoczy, Laurent L; Papavasiliou, F Nina FN; Diaz, Marilyn M
Publication Date: 2021

Variant appearance in text: GAA: P681H
PubMed Link: 34297786
Variant Present in the following documents:
  • pone.0255169.pdf
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