Publications:

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Regulation of Cell Proliferation and Nrf2-Mediated Antioxidant Defense: Conservation of Keap1 Cysteines and Nrf2 Binding Site in the Context of the Evolution of KLHL Family.

Life (Basel, Switzerland)

Shilovsky, Gregory A GA; Dibrova, Daria V DV

Publication Date: 2023-04-19

Variant appearance in text: KLHL19: G333C

PubMed Link: 37109574

Variant Present in the following documents:

• Main text
• life-13-01045.pdf

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Integrative pan-cancer genomic and transcriptomic analyses of refractory metastatic cancer.

Cancer Discovery

Pradat, Yoann Y; Viot, Julien J; Yurchenko, Andrey A AA; Gunbin, Konstantin K; Cerbone, Luigi L; Deloger, Marc M; Grisay, Guillaume G; Verlingue, Loic L; Scott, Veronique V; Padioleau, Ismael I; Panunzi, Leonardo L; Michiels, Stefan S; Hollebecque, Antoine A; Jules-Clement, Gerome G; Mezquita, Laura L; Laine, Antoine A; Loriot, Yohann Y; Besse, Benjamin B; Friboulet, Luc L; Andre, Fabrice F; Cournede, Paul-Henry PH; Gautheret, Daniel D; Nikolaev, Sergey I SI

Publication Date: 2023-03-02

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 36862804

Variant Present in the following documents:

• cd-22-0966_supplementary_tables_s1-s11_suppst1.xlsx, sheet 6

View BVdb publication page

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An EGFR L858R mutation identified in 1862 Chinese NSCLC patients can be a promising neoantigen vaccine therapeutic strategy.

Frontiers In Immunology

Lin, Jing J; Liu, Jun J; Hao, Shi-Guang SG; Lan, Bin B; Zheng, Xiao-Bin XB; Xiong, Jia-Ni JN; Zhang, Ying-Qian YQ; Gao, Xuan X; Chen, Chuan-Ben CB; Chen, Ling L; Huang, Yu-Fang YF; Luo, Hong H; Yi, Yu-Ting YT; Yi, Xin X; Lu, Jian-Ping JP; Zheng, Xiong-Wei XW; Chen, Gang G; Wang, Xue-Feng XF; Chen, Yu Y

Publication Date: 2022

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 36505399

Variant Present in the following documents:

• Table_2.xlsx, sheet 2

View BVdb publication page

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Design and characterization of a heterobifunctional degrader of KEAP1.

Redox Biology

Chen, Hao H; Nguyen, Nghi H NH; Magtoto, Charlene M CM; Cobbold, Simon A SA; Bidgood, Grace M GM; Meza Guzman, Lizeth G LG; Richardson, Lachlan W LW; Corbin, Jason J; Au, Amanda E AE; Lechtenberg, Bernhard C BC; Feltham, Rebecca R; Sutherland, Kate D KD; Grohmann, Christoph C; Nicholson, Sandra E SE; Sleebs, Brad E BE

Publication Date: 2022-11-26

Variant appearance in text: KEAP1: G333C

PubMed Link: 36473314

Variant Present in the following documents:

• Main text
• main.pdf

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Somatic mutation distribution across tumour cohorts provides a signal for positive selection in cancer.

Nature Communications

Boström, Martin M; Larsson, Erik E

Publication Date: 2022-11-17

Variant appearance in text: KEAP1: G333C

PubMed Link: 36396655

Variant Present in the following documents:

• 41467_2022_34746_MOESM10_ESM.xlsx, sheet 1

View BVdb publication page

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: KEAP1: G333C

PubMed Link: 36222846

Variant Present in the following documents:

• Main text
• ccr-22-1914_supplementary_data_2_suppds2.xlsx, sheet 1
• ccr-22-1914_supplementary_data_3_suppds3.xlsx, sheet 1
• 5343.pdf

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Targeting de novo lipogenesis and the Lands cycle induces ferroptosis in KRAS-mutant lung cancer.

Nature Communications

Bartolacci, Caterina C; Andreani, Cristina C; Vale, Gonçalo G; Berto, Stefano S; Melegari, Margherita M; Crouch, Anna Colleen AC; Baluya, Dodge L DL; Kemble, George G; Hodges, Kurt K; Starrett, Jacqueline J; Politi, Katerina K; Starnes, Sandra L SL; Lorenzini, Daniele D; Raso, Maria Gabriela MG; Solis Soto, Luisa M LM; Behrens, Carmen C; Kadara, Humam H; Gao, Boning B; Wistuba, Ignacio I II; Minna, John D JD; McDonald, Jeffrey G JG; Scaglioni, Pier Paolo PP

Publication Date: 2022-07-26

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 35882862

Variant Present in the following documents:

• 41467_2022_31963_MOESM13_ESM.xlsx, sheet 1

View BVdb publication page

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Snail acetylation by autophagy-derived acetyl-coenzyme A promotes invasion and metastasis of KRAS-LKB1 co-mutated lung cancer cells.

Cancer Communications (London, England)

Han, Jang Hee JH; Kim, Yong Keon YK; Kim, Hakhyun H; Lee, Jooyoung J; Oh, Myung Joon MJ; Kim, Sang Bum SB; Kim, Minjee M; Kim, Kook Hwan KH; Yoon, Hyun Ju HJ; Lee, Myung-Shik MS; Minna, John D JD; White, Michael A MA; Kim, Hyun Seok HS

Publication Date: 2022-08

Variant appearance in text: KEAP1: G333C

PubMed Link: 35838183

Variant Present in the following documents:

• Main text
• CAC2-42-716.pdf

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Reversal of doxorubicin resistance in lung cancer cells by neferine is explained by nuclear factor erythroid-derived 2-like 2 mediated lung resistance protein down regulation.

Cancer Drug Resistance (Alhambra, Calif.)

Paramasivan, Poornima P; Kumar, Jothi Dinesh JD; Baskaran, Rathinasamy R; Weng, Ching Feng CF; Padma, Viswanadha Vijaya VV

Publication Date: 2020

Variant appearance in text: KEAP1: G333C

PubMed Link: 35582448

Variant Present in the following documents:

• cdr-3-647.pdf

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miR-6077 promotes cisplatin/pemetrexed resistance in lung adenocarcinoma via CDKN1A/cell cycle arrest and KEAP1/ferroptosis pathways.

Molecular Therapy. Nucleic Acids

Bi, Guoshu G; Liang, Jiaqi J; Zhao, Mengnan M; Zhang, Huan H; Jin, Xing X; Lu, Tao T; Zheng, Yuansheng Y; Bian, Yunyi Y; Chen, Zhencong Z; Huang, Yiwei Y; Besskaya, Valeria V; Zhan, Cheng C; Wang, Qun Q; Tan, Lijie L

Publication Date: 2022-06-14

Variant appearance in text: KEAP1: G333C

PubMed Link: 35505963

Variant Present in the following documents:

• Main text
• main.pdf
• mmc2.pdf

View BVdb publication page

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A targetable CoQ-FSP1 axis drives ferroptosis- and radiation-resistance in KEAP1 inactive lung cancers.

Nature Communications

Koppula, Pranavi P; Lei, Guang G; Zhang, Yilei Y; Yan, Yuelong Y; Mao, Chao C; Kondiparthi, Lavanya L; Shi, Jiejun J; Liu, Xiaoguang X; Horbath, Amber A; Das, Molina M; Li, Wei W; Poyurovsky, Masha V MV; Olszewski, Kellen K; Gan, Boyi B

Publication Date: 2022-04-22

Variant appearance in text: KEAP1: G333C

PubMed Link: 35459868

Variant Present in the following documents:

• Main text
• 41467_2022_Article_29905.pdf
• 41467_2022_29905_MOESM1_ESM.pdf
• 41467_2022_29905_MOESM2_ESM.pdf

View BVdb publication page

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Cell Painting predicts impact of lung cancer variants.

Molecular Biology Of The Cell

Caicedo, Juan C JC; Arevalo, John J; Piccioni, Federica F; Bray, Mark-Anthony MA; Hartland, Cathy L CL; Wu, Xiaoyun X; Brooks, Angela N AN; Berger, Alice H AH; Boehm, Jesse S JS; Carpenter, Anne E AE; Singh, Shantanu S

Publication Date: 2022-05-15

Variant appearance in text: KEAP1: G333C

PubMed Link: 35353015

Variant Present in the following documents:

• Main text
• mbc-33-ar49.pdf

View BVdb publication page

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Clinic and genetic similarity assessments of atypical carcinoid, neuroendocrine neoplasm with atypical carcinoid morphology and elevated mitotic count and large cell neuroendocrine carcinoma.

Bmc Cancer

Zhang, Ying Y; Wang, Weiya W; Hu, Qianrong Q; Liang, Zuoyu Z; Zhou, Ping P; Tang, Yuan Y; Jiang, Lili L

Publication Date: 2022-03-24

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 35331190

Variant Present in the following documents:

• 12885_2022_9391_MOESM1_ESM.pdf

View BVdb publication page

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Identification of Immune-Related Gene Signatures in Lung Adenocarcinoma and Lung Squamous Cell Carcinoma.

Frontiers In Immunology

Li, Na N; Wang, Jiahong J; Zhan, Xianquan X

Publication Date: 2021

Variant appearance in text: KEAP1: 997G>T; Gly333Cys

PubMed Link: 34887858

Variant Present in the following documents:

• Table_3.xlsx, sheet 1
• Table_4.xlsx, sheet 1

View BVdb publication page

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Multiomics Landscape Uncovers the Molecular Mechanism of the Malignant Evolution of Lung Adenocarcinoma Cells to Chronic Low Dose Cadmium Exposure.

Frontiers In Oncology

Dai, Shun-Dong SD; Wang, Shuang S; Qin, Ya-Nan YN; Zhu, Jin-Chao JC

Publication Date: 2021

Variant appearance in text: KEAP1: G333C

PubMed Link: 34858801

Variant Present in the following documents:

• Table_1.xls, sheet 1

View BVdb publication page

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Activation of the NRF2 antioxidant program sensitizes tumors to G6PD inhibition.

Science Advances

Ding, Hongyu H; Chen, Zihong Z; Wu, Katherine K; Huang, Shih Ming SM; Wu, Warren L WL; LeBoeuf, Sarah E SE; Pillai, Ray G RG; Rabinowitz, Joshua D JD; Papagiannakopoulos, Thales T

Publication Date: 2021-11-19

Variant appearance in text: KEAP1: G333C

PubMed Link: 34788087

Variant Present in the following documents:

• Main text
• sciadv.abk1023.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: KEAP1: G333C

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Triptolide Downregulates the Expression of NRF2 Target Genes by Increasing Cytoplasmic Localization of NRF2 in A549 Cells.

Frontiers In Pharmacology

Nam, Le Ba LB; Choi, Won Jun WJ; Keum, Young-Sam YS

Publication Date: 2021

Variant appearance in text: KEAP1: G333C

PubMed Link: 34566633

Variant Present in the following documents:

• Main text
• fphar-12-680167.pdf

View BVdb publication page

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KEAP1 Cancer Mutants: A Large-Scale Molecular Dynamics Study of Protein Stability.

International Journal Of Molecular Sciences

Wilson, Carter J CJ; Chang, Megan M; Karttunen, Mikko M; Choy, Wing-Yiu WY

Publication Date: 2021-05-20

Variant appearance in text: KEAP1: G333C

PubMed Link: 34065616

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of a Stable, Non-Canonically Regulated Nrf2 Form in Lung Cancer Cells.

Antioxidants (Basel, Switzerland)

Mikac, Sara S; Rychłowski, Michał M; Dziadosz, Alicja A; Szabelska-Beresewicz, Alicja A; Fahraeus, Robin R; Hupp, Theodore T; Sznarkowska, Alicja A

Publication Date: 2021-05-15

Variant appearance in text: KEAP1: G333C

PubMed Link: 34063559

Variant Present in the following documents:

• Main text
• antioxidants-10-00786.pdf

View BVdb publication page

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KEAP1 Is Required for Artesunate Anticancer Activity in Non-Small-Cell Lung Cancer.

Cancers

Hill, Kristen S KS; McDowell, Anthony A; McCorkle, J Robert JR; Schuler, Erin E; Ellingson, Sally R SR; Plattner, Rina R; Kolesar, Jill M JM

Publication Date: 2021-04-14

Variant appearance in text: KEAP1: G333C

PubMed Link: 33920029

Variant Present in the following documents:

• Main text

View BVdb publication page

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Spatially interacting phosphorylation sites and mutations in cancer.

Nature Communications

Huang, Kuan-Lin KL; Scott, Adam D AD; Zhou, Daniel Cui DC; Wang, Liang-Bo LB; Weerasinghe, Amila A; Elmas, Abdulkadir A; Liu, Ruiyang R; Wu, Yige Y; Wendl, Michael C MC; Wyczalkowski, Matthew A MA; Baral, Jessika J; Sengupta, Sohini S; Lai, Chin-Wen CW; Ruggles, Kelly K; Payne, Samuel H SH; Raphael, Benjamin B; Fenyö, David D; Chen, Ken K; Mills, Gordon G; Ding, Li L

Publication Date: 2021-04-19

Variant appearance in text: KEAP1: G333C

PubMed Link: 33875650

Variant Present in the following documents:

• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 1
• 41467_2021_22481_MOESM4_ESM.xlsx, sheet 6

View BVdb publication page

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Pan-cancer circulating tumor DNA detection in over 10,000 Chinese patients.

Nature Communications

Zhang, Yongliang Y; Yao, Yu Y; Xu, Yaping Y; Li, Lifeng L; Gong, Yan Y; Zhang, Kai K; Zhang, Meng M; Guan, Yanfang Y; Chang, Lianpeng L; Xia, Xuefeng X; Li, Lin L; Jia, Shuqin S; Zeng, Qiang Q

Publication Date: 2021-01-04

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 33397889

Variant Present in the following documents:

• 41467_2020_20162_MOESM6_ESM.xlsx, sheet 1

View BVdb publication page

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Enhancer remodeling promotes tumor-initiating activity in NRF2-activated non-small cell lung cancers.

Nature Communications

Okazaki, Keito K; Anzawa, Hayato H; Liu, Zun Z; Ota, Nao N; Kitamura, Hiroshi H; Onodera, Yoshiaki Y; Alam, Md Morshedul MM; Matsumaru, Daisuke D; Suzuki, Takuma T; Katsuoka, Fumiki F; Tadaka, Shu S; Motoike, Ikuko I; Watanabe, Mika M; Hayasaka, Kazuki K; Sakurada, Akira A; Okada, Yoshinori Y; Yamamoto, Masayuki M; Suzuki, Takashi T; Kinoshita, Kengo K; Sekine, Hiroki H; Motohashi, Hozumi H

Publication Date: 2020-11-20

Variant appearance in text: KEAP1: G333C

PubMed Link: 33219226

Variant Present in the following documents:

• 41467_2020_19593_MOESM4_ESM.xlsx, sheet 8

View BVdb publication page

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KEAP1 Mutations Drive Tumorigenesis by Suppressing SOX9 Ubiquitination and Degradation.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)

Shao, Na N; Huang, Hong H; Idris, Muhammad M; Peng, Xu X; Xu, Feng F; Dong, Shiwu S; Liu, Chungang C

Publication Date: 2020-11

Variant appearance in text: KEAP1: G333C

PubMed Link: 33173725

Variant Present in the following documents:

• Main text
• ADVS-7-2001018-s001.pdf
• ADVS-7-2001018.pdf

View BVdb publication page

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Deep phylogeny of cancer drivers and compensatory mutations.

Communications Biology

Rochman, Nash D ND; Wolf, Yuri I YI; Koonin, Eugene V EV

Publication Date: 2020-10-02

Variant appearance in text: KEAP1: G333C

PubMed Link: 33009502

Variant Present in the following documents:

• Main text
• 42003_2020_1276_MOESM14_ESM.xlsx, sheet 1
• 42003_2020_Article_1276.pdf

View BVdb publication page

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Geldanamycin-Derived HSP90 Inhibitors Are Synthetic Lethal with NRF2.

Molecular And Cellular Biology

Baird, Liam L; Suzuki, Takafumi T; Takahashi, Yushi Y; Hishinuma, Eiji E; Saigusa, Daisuke D; Yamamoto, Masayuki M

Publication Date: 2020-10-26

Variant appearance in text: KEAP1: G333C

PubMed Link: 32868290

Variant Present in the following documents:

• Main text

View BVdb publication page

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Identification of relevant genetic alterations in cancer using topological data analysis.

Nature Communications

Rabadán, Raúl R; Mohamedi, Yamina Y; Rubin, Udi U; Chu, Tim T; Alghalith, Adam N AN; Elliott, Oliver O; Arnés, Luis L; Cal, Santiago S; Obaya, Álvaro J ÁJ; Levine, Arnold J AJ; Cámara, Pablo G PG

Publication Date: 2020-07-30

Variant appearance in text: KEAP1: G333C

PubMed Link: 32732999

Variant Present in the following documents:

• 41467_2020_17659_MOESM3_ESM.xls, sheet 1

View BVdb publication page

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Loss-of-function mutations in KEAP1 drive lung cancer progression via KEAP1/NRF2 pathway activation.

Cell Communication And Signaling : Ccs

Gong, Meiling M; Li, Yan Y; Ye, Xiaoping X; Zhang, Linlin L; Wang, Zhifang Z; Xu, Xiaowen X; Shen, Yejing Y; Zheng, Cuixia C

Publication Date: 2020-06-23

Variant appearance in text: KEAP1: G333C

PubMed Link: 32576270

Variant Present in the following documents:

• Main text
• 12964_2020_Article_568.pdf

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Integrated data analysis reveals significant associations of KEAP1 mutations with DNA methylation alterations in lung adenocarcinomas.

Aging

Elshaer, Mohamed M; ElManawy, Ahmed Islam AI; Hammad, Ahmed A; Namani, Akhileshwar A; Wang, Xiu Jun XJ; Tang, Xiuwen X

Publication Date: 2020-04-23

Variant appearance in text: KEAP1: G333C

PubMed Link: 32327612

Variant Present in the following documents:

• aging-12-103068-s001..xlsx, sheet 1

View BVdb publication page

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: KEAP1: G333C

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

View BVdb publication page

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Inhibition of TXNRD or SOD1 overcomes NRF2-mediated resistance to β-lapachone.

Redox Biology

Torrente, Laura L; Prieto-Farigua, Nicolas N; Falzone, Aimee A; Elkins, Cody M CM; Boothman, David A DA; Haura, Eric B EB; DeNicola, Gina M GM

Publication Date: 2020-02

Variant appearance in text: KEAP1: G333C

PubMed Link: 32007910

Variant Present in the following documents:

• mmc1.pdf

View BVdb publication page

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Diversity spectrum analysis identifies mutation-specific effects of cancer driver genes.

Communications Biology

Dong, Xiaobao X; Huang, Dandan D; Yi, Xianfu X; Zhang, Shijie S; Wang, Zhao Z; Yan, Bin B; Chung Sham, Pak P; Chen, Kexin K; Jun Li, Mulin M

Publication Date: 2020-01-07

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 31925297

Variant Present in the following documents:

• 42003_2019_736_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Impacts of NRF2 activation in non-small-cell lung cancer cell lines on extracellular metabolites.

Cancer Science

Saigusa, Daisuke D; Motoike, Ikuko N IN; Saito, Sakae S; Zorzi, Michael M; Aoki, Yuichi Y; Kitamura, Hiroshi H; Suzuki, Mikiko M; Katsuoka, Fumiki F; Ishii, Hirofumi H; Kinoshita, Kengo K; Motohashi, Hozumi H; Yamamoto, Masayuki M

Publication Date: 2020-02

Variant appearance in text: KEAP1: 997G>T

PubMed Link: 31828882

Variant Present in the following documents:

• CAS-111-667-s002.xlsx, sheet 2

View BVdb publication page

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The balance between NRF2/GSH antioxidant mediated pathway and DNA repair modulates cisplatin resistance in lung cancer cells.

Scientific Reports

Silva, Matheus Molina MM; Rocha, Clarissa Ribeiro Reily CRR; Kinker, Gabriela Sarti GS; Pelegrini, Alessandra Luiza AL; Menck, Carlos Frederico Martins CFM

Publication Date: 2019-11-27

Variant appearance in text: KEAP1: G333C

PubMed Link: 31776385

Variant Present in the following documents:

• Main text

View BVdb publication page

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Nestin regulates cellular redox homeostasis in lung cancer through the Keap1-Nrf2 feedback loop.

Nature Communications

Wang, Jiancheng J; Lu, Qiying Q; Cai, Jianye J; Wang, Yi Y; Lai, Xiaofan X; Qiu, Yuan Y; Huang, Yinong Y; Ke, Qiong Q; Zhang, Yanan Y; Guan, Yuanjun Y; Wu, Haoxiang H; Wang, Yuanyuan Y; Liu, Xin X; Shi, Yue Y; Zhang, Kang K; Wang, Maosheng M; Peng Xiang, Andy A

Publication Date: 2019-11-06

Variant appearance in text: KEAP1: G333C

PubMed Link: 31695040

Variant Present in the following documents:

• Main text
• 41467_2019_Article_12925.pdf
• 41467_2019_12925_MOESM2_ESM.pdf

View BVdb publication page

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Dual roles and therapeutic potential of Keap1-Nrf2 pathway in pancreatic cancer: a systematic review.

Cell Communication And Signaling : Ccs

Qin, Jiang-Jiang JJ; Cheng, Xiang-Dong XD; Zhang, Jia J; Zhang, Wei-Dong WD

Publication Date: 2019-09-11

Variant appearance in text: KEAP1: G333C

PubMed Link: 31511020

Variant Present in the following documents:

• Main text

View BVdb publication page

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Methylation Density Pattern of KEAP1 Gene in Lung Cancer Cell Lines Detected by Quantitative Methylation Specific PCR and Pyrosequencing.

International Journal Of Molecular Sciences

Fabrizio, Federico Pio FP; Sparaneo, Angelo A; Centra, Flavia F; Trombetta, Domenico D; Storlazzi, Clelia Tiziana CT; Graziano, Paolo P; Maiello, Evaristo E; Fazio, Vito Michele VM; Muscarella, Lucia Anna LA

Publication Date: 2019-05-31

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 31159323

Variant Present in the following documents:

• Main text
• ijms-20-02697.pdf

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Analysis on GENIE reveals novel recurrent variants that affect molecular diagnosis of sizable number of cancer patients.

Bmc Cancer

Koyama, Takahiko T; Rhrissorrakrai, Kahn K; Parida, Laxmi L

Publication Date: 2019-02-01

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 30709382

Variant Present in the following documents:

• 12885_2019_5313_MOESM2_ESM.xlsx, sheet 1
• 12885_2019_5313_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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A catalogue of somatic NRF2 gain-of-function mutations in cancer.

Scientific Reports

Kerins, Michael John MJ; Ooi, Aikseng A

Publication Date: 2018-08-27

Variant appearance in text: KEAP1: G333C

PubMed Link: 30150714

Variant Present in the following documents:

• Main text
• 41598_2018_Article_31281.pdf

View BVdb publication page

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Genetic and transcriptional evolution alters cancer cell line drug response.

Nature

Ben-David, Uri U; Siranosian, Benjamin B; Ha, Gavin G; Tang, Helen H; Oren, Yaara Y; Hinohara, Kunihiko K; Strathdee, Craig A CA; Dempster, Joshua J; Lyons, Nicholas J NJ; Burns, Robert R; Nag, Anwesha A; Kugener, Guillaume G; Cimini, Beth B; Tsvetkov, Peter P; Maruvka, Yosef E YE; O'Rourke, Ryan R; Garrity, Anthony A; Tubelli, Andrew A AA; Bandopadhayay, Pratiti P; Tsherniak, Aviad A; Vazquez, Francisca F; Wong, Bang B; Birger, Chet C; Ghandi, Mahmoud M; Thorner, Aaron R AR; Bittker, Joshua A JA; Meyerson, Matthew M; Getz, Gad G; Beroukhim, Rameen R; Golub, Todd R TR

Publication Date: 2018-08

Variant appearance in text: KEAP1: 997G>T; G333C

PubMed Link: 30089904

Variant Present in the following documents:

• NIHMS977514-supplement-Sup_Table_17.xlsx, sheet 1

View BVdb publication page

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MHC class II restricted neoantigen peptides predicted by clonal mutation analysis in lung adenocarcinoma patients: implications on prognostic immunological biomarker and vaccine design.

Bmc Genomics

Cai, Weijing W; Zhou, Dapeng D; Wu, Weibo W; Tan, Wen Ling WL; Wang, Jiaqian J; Zhou, Caicun C; Lou, Yanyan Y

Publication Date: 2018-08-03

Variant appearance in text: KEAP1: G333C

PubMed Link: 30075702

Variant Present in the following documents:

• 12864_2018_4958_MOESM4_ESM.xlsx, sheet 1
• 12864_2018_4958_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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"Keaping" a lid on lung cancer: the Keap1-Nrf2 pathway.

Cell Cycle (Georgetown, Tex.)

Best, Sarah A SA; Sutherland, Kate D KD

Publication Date: 2018

Variant appearance in text: KEAP1: G333C

PubMed Link: 30009666

Variant Present in the following documents:

• Main text

View BVdb publication page

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