Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients.
Nature Communications
Fernando, Tharu M TM; Piskol, Robert R; Bainer, Russell R; Sokol, Ethan S ES; Trabucco, Sally E SE; Zhang, Qing Q; Trinh, Huong H; Maund, Sophia S; Kschonsak, Marc M; Chaudhuri, Subhra S; Modrusan, Zora Z; Januario, Thomas T; Yauch, Robert L RL
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.
Nature Structural & Molecular Biology
Hodges, H Courtney HC; Stanton, Benjamin Z BZ; Cermakova, Katerina K; Chang, Chiung-Ying CY; Miller, Erik L EL; Kirkland, Jacob G JG; Ku, Wai Lim WL; Veverka, Vaclav V; Zhao, Keji K; Crabtree, Gerald R GR