Functional characterization of SMARCA4 variants identified by targeted exome-sequencing of 131,668 cancer patients.
Nature Communications
Fernando, Tharu M TM; Piskol, Robert R; Bainer, Russell R; Sokol, Ethan S ES; Trabucco, Sally E SE; Zhang, Qing Q; Trinh, Huong H; Maund, Sophia S; Kschonsak, Marc M; Chaudhuri, Subhra S; Modrusan, Zora Z; Januario, Thomas T; Yauch, Robert L RL
mTOR Signaling and SREBP Activity Increase FADS2 Expression and Can Activate Sapienate Biosynthesis.
Cell Reports
Triki, Mouna M; Rinaldi, Gianmarco G; Planque, Melanie M; Broekaert, Dorien D; Winkelkotte, Alina M AM; Maier, Carina R CR; Janaki Raman, Sudha S; Vandekeere, Anke A; Van Elsen, Joke J; Orth, Martin F MF; Grünewald, Thomas G P TGP; Schulze, Almut A; Fendt, Sarah-Maria SM
Integrative Analysis Defines Distinct Prognostic Subgroups of Intrahepatic Cholangiocarcinoma.
Hepatology (Baltimore, Md.)
Goeppert, Benjamin B; Toth, Reka R; Singer, Stephan S; Albrecht, Thomas T; Lipka, Daniel B DB; Lutsik, Pavlo P; Brocks, David D; Baehr, Marion M; Muecke, Oliver O; Assenov, Yassen Y; Gu, Lei L; Endris, Volker V; Stenzinger, Albrecht A; Mehrabi, Arianeb A; Schirmacher, Peter P; Plass, Christoph C; Weichenhan, Dieter D; Roessler, Stephanie S
Publication Date: 2019-05
Variant appearance in text: SMARCA4: 2646A>C; E882D
Dominant-negative SMARCA4 mutants alter the accessibility landscape of tissue-unrestricted enhancers.
Nature Structural & Molecular Biology
Hodges, H Courtney HC; Stanton, Benjamin Z BZ; Cermakova, Katerina K; Chang, Chiung-Ying CY; Miller, Erik L EL; Kirkland, Jacob G JG; Ku, Wai Lim WL; Veverka, Vaclav V; Zhao, Keji K; Crabtree, Gerald R GR