Single Nucleotide Polymorphisms' Causal Structure Robustness within Coronary Artery Disease Patients.
Biology
Ganopoulou, Maria M; Moysiadis, Theodoros T; Gounaris, Anastasios A; Mittas, Nikolaos N; Chatzopoulou, Fani F; Chatzidimitriou, Dimitrios D; Sianos, Georgios G; Vizirianakis, Ioannis S IS; Angelis, Lefteris L
Gene-diet interactions and cardiovascular diseases: a systematic review of observational and clinical trials.
Bmc Cardiovascular Disorders
Roa-Díaz, Zayne M ZM; Teuscher, Julian J; Gamba, Magda M; Bundo, Marvin M; Grisotto, Giorgia G; Wehrli, Faina F; Gamboa, Edna E; Rojas, Lyda Z LZ; Gómez-Ochoa, Sergio A SA; Verhoog, Sanne S; Vargas, Manuel Frias MF; Minder, Beatrice B; Franco, Oscar H OH; Dehghan, Abbas A; Pazoki, Raha R; Marques-Vidal, Pedro P; Muka, Taulant T
Analysis of 61 SNPs from the CAD specific genomic loci reveals unique set of SNPs as significant markers in the Southern Indian population of Hyderabad.
The Pharmacogenetics of Statin Therapy on Clinical Events: No Evidence that Genetic Variation Affects Statin Response on Myocardial Infarction.
Frontiers In Pharmacology
Trompet, Stella S; Postmus, Iris I; Warren, Helen R HR; Noordam, Raymond R; Smit, Roelof A J RAJ; Theusch, Elizabeth E; Li, Xiaohui X; Arsenault, Benoit B; Chasman, Daniel I DI; Hitman, Graham A GA; Munroe, Patricia B PB; Rotter, Jerome I JI; Psaty, Bruce M BM; Caulfield, Mark J MJ; Krauss, Ron M RM; Cupples, Adrienne L AL; Jukema, Wouter J WJ
Polygenic risk scores predict diabetes complications and their response to intensive blood pressure and glucose control.
Diabetologia
Tremblay, Johanne J; Haloui, Mounsif M; Attaoua, Redha R; Tahir, Ramzan R; Hishmih, Camil C; Harvey, François F; Marois-Blanchet, François-Christophe FC; Long, Carole C; Simon, Paul P; Santucci, Lara L; Hizel, Candan C; Chalmers, John J; Marre, Michel M; Harrap, Stephen S; Cífková, Renata R; Krajčoviechová, Alena A; Matthews, David R DR; Williams, Bryan B; Poulter, Neil N; Zoungas, Sophia S; Colagiuri, Stephen S; Mancia, Giuseppe G; Grobbee, Diederick E DE; Rodgers, Anthony A; Liu, Liusheng L; Agbessi, Mawussé M; Bruat, Vanessa V; Favé, Marie-Julie MJ; Harwood, Michelle P MP; Awadalla, Philip P; Woodward, Mark M; Hussin, Julie G JG; Hamet, Pavel P
Using genetic variants to evaluate the causal effect of cholesterol lowering on head and neck cancer risk: A Mendelian randomization study.
Plos Genetics
Gormley, Mark M; Yarmolinsky, James J; Dudding, Tom T; Burrows, Kimberley K; Martin, Richard M RM; Thomas, Steven S; Tyrrell, Jessica J; Brennan, Paul P; Pring, Miranda M; Boccia, Stefania S; Olshan, Andrew F AF; Diergaarde, Brenda B; Hung, Rayjean J RJ; Liu, Geoffrey G; Legge, Danny D; Tajara, Eloiza H EH; Severino, Patricia P; Lacko, Martin M; Ness, Andrew R AR; Davey Smith, George G; Vincent, Emma E EE; Richmond, Rebecca C RC
Identification of methylation changes associated with positive and negative growth deviance in Gambian infants using a targeted methyl sequencing approach of genomic DNA.
Faseb Bioadvances
Quilter, Claire R CR; Harvey, Kerry M KM; Bauer, Julien J; Skinner, Benjamin M BM; Gomez, Maria M; Shrivastava, Manu M; Doel, Andrew M AM; Drammeh, Saikou S; Dunger, David B DB; Moore, Sophie E SE; Ong, Ken K KK; Prentice, Andrew M AM; Bernstein, Robin M RM; Sargent, Carole A CA; Affara, Nabeel A NA
Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.
Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Novel risk genes identified in a genome-wide association study for coronary artery disease in patients with type 1 diabetes.
Cardiovascular Diabetology
Charmet, Romain R; Duffy, Seamus S; Keshavarzi, Sareh S; Gyorgy, Beata B; Marre, Michel M; Rossing, Peter P; McKnight, Amy Jayne AJ; Maxwell, Alexander P AP; Ahluwalia, Tarun Veer Singh TVS; Paterson, Andrew D AD; Trégouët, David-Alexandre DA; Hadjadj, Samy S
Correlation of rs1122608 SNP with acute myocardial infarction susceptibility and clinical characteristics in a Chinese Han population: A case-control study.
Anatolian Journal Of Cardiology
Chen, Quan Fang QF; Wang, Wei W; Huang, Zhou Z; Huang, Dong Ling DL; Li, Tian T; Wang, Fan F; Li, Jun J
Genetic variation associated with cardiovascular risk in autoimmune diseases.
Plos One
Perrotti, Pedro P PP; Aterido, Adrià A; Fernández-Nebro, Antonio A; Cañete, Juan D JD; Ferrándiz, Carlos C; Tornero, Jesús J; Gisbert, Javier P JP; Domènech, Eugeni E; Fernández-Gutiérrez, Benjamín B; Gomollón, Fernando F; García-Planella, Esther E; Fernández, Emilia E; Sanmartí, Raimon R; Gratacós, Jordi J; Martínez-Taboada, Víctor Manuel VM; Rodríguez-Rodríguez, Luís L; Palau, Núria N; Tortosa, Raül R; Corbeto, Mireia L ML; Lasanta, María L ML; Marsal, Sara S; Julià, Antonio A; ,
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.
Journal Of The American College Of Cardiology
Webb, Thomas R TR; Erdmann, Jeanette J; Stirrups, Kathleen E KE; Stitziel, Nathan O NO; Masca, Nicholas G D NG; Jansen, Henning H; Kanoni, Stavroula S; Nelson, Christopher P CP; Ferrario, Paola G PG; König, Inke R IR; Eicher, John D JD; Johnson, Andrew D AD; Hamby, Stephen E SE; Betsholtz, Christer C; Ruusalepp, Arno A; Franzén, Oscar O; Schadt, Eric E EE; Björkegren, Johan L M JL; Weeke, Peter E PE; Auer, Paul L PL; Schick, Ursula M UM; Lu, Yingchang Y; Zhang, He H; Dube, Marie-Pierre MP; Goel, Anuj A; Farrall, Martin M; Peloso, Gina M GM; Won, Hong-Hee HH; Do, Ron R; van Iperen, Erik E; Kruppa, Jochen J; Mahajan, Anubha A; Scott, Robert A RA; Willenborg, Christina C; Braund, Peter S PS; van Capelleveen, Julian C JC; Doney, Alex S F AS; Donnelly, Louise A LA; Asselta, Rosanna R; Merlini, Pier A PA; Duga, Stefano S; Marziliano, Nicola N; Denny, Josh C JC; Shaffer, Christian C; El-Mokhtari, Nour Eddine NE; Franke, Andre A; Heilmann, Stefanie S; Hengstenberg, Christian C; Hoffmann, Per P; Holmen, Oddgeir L OL; Hveem, Kristian K; Jansson, Jan-Håkan JH; Jöckel, Karl-Heinz KH; Kessler, Thorsten T; Kriebel, Jennifer J; Laugwitz, Karl L KL; Marouli, Eirini E; Martinelli, Nicola N; McCarthy, Mark I MI; Van Zuydam, Natalie R NR; Meisinger, Christa C; Esko, Tõnu T; Mihailov, Evelin E; Escher, Stefan A SA; Alver, Maris M; Moebus, Susanne S; Morris, Andrew D AD; Virtamo, Jarma J; Nikpay, Majid M; Olivieri, Oliviero O; Provost, Sylvie S; AlQarawi, Alaa A; Robertson, Neil R NR; Akinsansya, Karen O KO; Reilly, Dermot F DF; Vogt, Thomas F TF; Yin, Wu W; Asselbergs, Folkert W FW; Kooperberg, Charles C; Jackson, Rebecca D RD; Stahl, Eli E; Müller-Nurasyid, Martina M; Strauch, Konstantin K; Varga, Tibor V TV; Waldenberger, Melanie M; , ; Zeng, Lingyao L; Chowdhury, Rajiv R; Salomaa, Veikko V; Ford, Ian I; Jukema, J Wouter JW; Amouyel, Philippe P; Kontto, Jukka J; , ; Nordestgaard, Børge G BG; Ferrières, Jean J; Saleheen, Danish D; Sattar, Naveed N; Surendran, Praveen P; Wagner, Aline A; Young, Robin R; Howson, Joanna M M JM; Butterworth, Adam S AS; Danesh, John J; Ardissino, Diego D; Bottinger, Erwin P EP; Erbel, Raimund R; Franks, Paul W PW; Girelli, Domenico D; Hall, Alistair S AS; Hovingh, G Kees GK; Kastrati, Adnan A; Lieb, Wolfgang W; Meitinger, Thomas T; Kraus, William E WE; Shah, Svati H SH; McPherson, Ruth R; Orho-Melander, Marju M; Melander, Olle O; Metspalu, Andres A; Palmer, Colin N A CN; Peters, Annette A; Rader, Daniel J DJ; Reilly, Muredach P MP; Loos, Ruth J F RJ; Reiner, Alex P AP; Roden, Dan M DM; Tardif, Jean-Claude JC; Thompson, John R JR; Wareham, Nicholas J NJ; Watkins, Hugh H; Willer, Cristen J CJ; Samani, Nilesh J NJ; Schunkert, Heribert H; Deloukas, Panos P; Kathiresan, Sekar S; ,
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.
Circulation
Benjamin, Emelia J EJ; Blaha, Michael J MJ; Chiuve, Stephanie E SE; Cushman, Mary M; Das, Sandeep R SR; Deo, Rajat R; de Ferranti, Sarah D SD; Floyd, James J; Fornage, Myriam M; Gillespie, Cathleen C; Isasi, Carmen R CR; Jiménez, Monik C MC; Jordan, Lori Chaffin LC; Judd, Suzanne E SE; Lackland, Daniel D; Lichtman, Judith H JH; Lisabeth, Lynda L; Liu, Simin S; Longenecker, Chris T CT; Mackey, Rachel H RH; Matsushita, Kunihiro K; Mozaffarian, Dariush D; Mussolino, Michael E ME; Nasir, Khurram K; Neumar, Robert W RW; Palaniappan, Latha L; Pandey, Dilip K DK; Thiagarajan, Ravi R RR; Reeves, Mathew J MJ; Ritchey, Matthew M; Rodriguez, Carlos J CJ; Roth, Gregory A GA; Rosamond, Wayne D WD; Sasson, Comilla C; Towfighi, Amytis A; Tsao, Connie W CW; Turner, Melanie B MB; Virani, Salim S SS; Voeks, Jenifer H JH; Willey, Joshua Z JZ; Wilkins, John T JT; Wu, Jason Hy JH; Alger, Heather M HM; Wong, Sally S SS; Muntner, Paul P; ,
Novel genetic loci associated with long-term deterioration in blood lipid concentrations and coronary artery disease in European adults.
International Journal Of Epidemiology
Varga, Tibor V TV; Kurbasic, Azra A; Aine, Mattias M; Eriksson, Pontus P; Ali, Ashfaq A; Hindy, George G; Gustafsson, Stefan S; Luan, Jian'an J; Shungin, Dmitry D; Chen, Yan Y; Schulz, Christina-Alexandra CA; Nilsson, Peter M PM; Hallmans, Göran G; Barroso, Inês I; Deloukas, Panos P; Langenberg, Claudia C; Scott, Robert A RA; Wareham, Nicholas J NJ; Lind, Lars L; Ingelsson, Erik E; Melander, Olle O; Orho-Melander, Marju M; Renström, Frida F; Franks, Paul W PW
Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population.
Arthritis & Rheumatology (Hoboken, N.J.)
Ferraz-Amaro, Iván I; Winchester, Robert R; Gregersen, Peter K PK; Reynolds, Richard J RJ; Wasko, Mary Chester MC; Oeser, Anette A; Chung, Cecilia P CP; Stein, C Michael CM; Giles, Jon T JT; Bathon, Joan M JM
Detailed analysis of association between common single nucleotide polymorphisms and subclinical atherosclerosis: The Multi-ethnic Study of Atherosclerosis.
Data In Brief
Vargas, Jose D JD; Manichaikul, Ani A; Wang, Xin-Qun XQ; Rich, Stephen S SS; Rotter, Jerome I JI; Post, Wendy S WS; Polak, Joseph F JF; Budoff, Matthew J MJ; Bluemke, David A DA
Genome-Wide Association Study for Incident Myocardial Infarction and Coronary Heart Disease in Prospective Cohort Studies: The CHARGE Consortium.
Plos One
Dehghan, Abbas A; Bis, Joshua C JC; White, Charles C CC; Smith, Albert Vernon AV; Morrison, Alanna C AC; Cupples, L Adrienne LA; Trompet, Stella S; Chasman, Daniel I DI; Lumley, Thomas T; Völker, Uwe U; Buckley, Brendan M BM; Ding, Jingzhong J; Jensen, Majken K MK; Folsom, Aaron R AR; Kritchevsky, Stephen B SB; Girman, Cynthia J CJ; Ford, Ian I; Dörr, Marcus M; Salomaa, Veikko V; Uitterlinden, André G AG; Eiriksdottir, Gudny G; Vasan, Ramachandran S RS; Franceschini, Nora N; Carty, Cara L CL; Virtamo, Jarmo J; Demissie, Serkalem S; Amouyel, Philippe P; Arveiler, Dominique D; Heckbert, Susan R SR; Ferrières, Jean J; Ducimetière, Pierre P; Smith, Nicholas L NL; Wang, Ying A YA; Siscovick, David S DS; Rice, Kenneth M KM; Wiklund, Per-Gunnar PG; Taylor, Kent D KD; Evans, Alun A; Kee, Frank F; Rotter, Jerome I JI; Karvanen, Juha J; Kuulasmaa, Kari K; Heiss, Gerardo G; Kraft, Peter P; Launer, Lenore J LJ; Hofman, Albert A; Markus, Marcello R P MR; Rose, Lynda M LM; Silander, Kaisa K; Wagner, Peter P; Benjamin, Emelia J EJ; Lohman, Kurt K; Stott, David J DJ; Rivadeneira, Fernando F; Harris, Tamara B TB; Levy, Daniel D; Liu, Yongmei Y; Rimm, Eric B EB; Jukema, J Wouter JW; Völzke, Henry H; Ridker, Paul M PM; Blankenberg, Stefan S; Franco, Oscar H OH; Gudnason, Vilmundur V; Psaty, Bruce M BM; Boerwinkle, Eric E; O'Donnell, Christopher J CJ
Prediction of Causal Candidate Genes in Coronary Artery Disease Loci.
Arteriosclerosis, Thrombosis, And Vascular Biology
Brænne, Ingrid I; Civelek, Mete M; Vilne, Baiba B; Di Narzo, Antonio A; Johnson, Andrew D AD; Zhao, Yuqi Y; Reiz, Benedikt B; Codoni, Veronica V; Webb, Thomas R TR; Foroughi Asl, Hassan H; Hamby, Stephen E SE; Zeng, Lingyao L; Trégouët, David-Alexandre DA; Hao, Ke K; Topol, Eric J EJ; Schadt, Eric E EE; Yang, Xia X; Samani, Nilesh J NJ; Björkegren, Johan L M JL; Erdmann, Jeanette J; Schunkert, Heribert H; Lusis, Aldons J AJ; ,
Genetic risk, coronary heart disease events, and the clinical benefit of statin therapy: an analysis of primary and secondary prevention trials.
Lancet (London, England)
Mega, J L JL; Stitziel, N O NO; Smith, J G JG; Chasman, D I DI; Caulfield, M M; Devlin, J J JJ; Nordio, F F; Hyde, C C; Cannon, C P CP; Sacks, F F; Poulter, N N; Sever, P P; Ridker, P M PM; Braunwald, E E; Melander, O O; Kathiresan, S S; Sabatine, M S MS
Basic concepts and potential applications of genetics and genomics for cardiovascular and stroke clinicians: a scientific statement from the American Heart Association.
Circulation. Cardiovascular Genetics
Musunuru, Kiran K; Hickey, Kathleen T KT; Al-Khatib, Sana M SM; Delles, Christian C; Fornage, Myriam M; Fox, Caroline S CS; Frazier, Lorraine L; Gelb, Bruce D BD; Herrington, David M DM; Lanfear, David E DE; Rosand, Jonathan J; ,
Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.
Plos One
Franceschini, Nora N; Hu, Yijuan Y; Reiner, Alex P AP; Buyske, Steven S; Nalls, Mike M; Yanek, Lisa R LR; Li, Yun Y; Hindorff, Lucia A LA; Cole, Shelley A SA; Howard, Barbara V BV; Stafford, Jeanette M JM; Carty, Cara L CL; Sethupathy, Praveen P; Martin, Lisa W LW; Lin, Dan-Yu DY; Johnson, Karen C KC; Becker, Lewis C LC; North, Kari E KE; Dehghan, Abbas A; Bis, Joshua C JC; Liu, Yongmei Y; Greenland, Philip P; Manson, JoAnn E JE; Maeda, Nobuyo N; Garcia, Melissa M; Harris, Tamara B TB; Becker, Diane M DM; O'Donnell, Christopher C; Heiss, Gerardo G; Kooperberg, Charles C; Boerwinkle, Eric E
Identifying genetic risk variants for coronary heart disease in familial hypercholesterolemia: an extreme genetics approach.
European Journal Of Human Genetics : Ejhg
Versmissen, Jorie J; Oosterveer, Daniëlla M DM; Yazdanpanah, Mojgan M; Dehghan, Abbas A; Hólm, Hilma H; Erdman, Jeanette J; Aulchenko, Yurii S YS; Thorleifsson, Gudmar G; Schunkert, Heribert H; Huijgen, Roeland R; Vongpromek, Ranitha R; Uitterlinden, André G AG; Defesche, Joep C JC; van Duijn, Cornelia M CM; Mulder, Monique M; Dadd, Tony T; Karlsson, Hróbjartur D HD; Ordovas, Jose J; Kindt, Iris I; Jarman, Amelia A; Hofman, Albert A; van Vark-van der Zee, Leonie L; Blommesteijn-Touw, Adriana C AC; Kwekkeboom, Jaap J; Liem, Anho H AH; van der Ouderaa, Frans J FJ; Calandra, Sebastiano S; Bertolini, Stefano S; Averna, Maurizio M; Langslet, Gisle G; Ose, Leiv L; Ros, Emilio E; Almagro, Fátima F; de Leeuw, Peter W PW; Civeira, Fernando F; Masana, Luis L; Pintó, Xavier X; Simoons, Maarten L ML; Schinkel, Arend F L AF; Green, Martin R MR; Zwinderman, Aeilko H AH; Johnson, Keith J KJ; Schaefer, Arne A; Neil, Andrew A; Witteman, Jacqueline C M JC; Humphries, Steve E SE; Kastelein, John J P JJ; Sijbrands, Eric J G EJ
Additive influence of genetic predisposition and conventional risk factors in the incidence of coronary heart disease: a population-based study in Greece.
Bmj Open
Yiannakouris, Nikos N; Katsoulis, Michail M; Trichopoulou, Antonia A; Ordovas, Jose M JM; Trichopoulos, Dimitrios D
Heart disease and stroke statistics--2014 update: a report from the American Heart Association.
Circulation
Go, Alan S AS; Mozaffarian, Dariush D; Roger, Véronique L VL; Benjamin, Emelia J EJ; Berry, Jarett D JD; Blaha, Michael J MJ; Dai, Shifan S; Ford, Earl S ES; Fox, Caroline S CS; Franco, Sheila S; Fullerton, Heather J HJ; Gillespie, Cathleen C; Hailpern, Susan M SM; Heit, John A JA; Howard, Virginia J VJ; Huffman, Mark D MD; Judd, Suzanne E SE; Kissela, Brett M BM; Kittner, Steven J SJ; Lackland, Daniel T DT; Lichtman, Judith H JH; Lisabeth, Lynda D LD; Mackey, Rachel H RH; Magid, David J DJ; Marcus, Gregory M GM; Marelli, Ariane A; Matchar, David B DB; McGuire, Darren K DK; Mohler, Emile R ER; Moy, Claudia S CS; Mussolino, Michael E ME; Neumar, Robert W RW; Nichol, Graham G; Pandey, Dilip K DK; Paynter, Nina P NP; Reeves, Matthew J MJ; Sorlie, Paul D PD; Stein, Joel J; Towfighi, Amytis A; Turan, Tanya N TN; Virani, Salim S SS; Wong, Nathan D ND; Woo, Daniel D; Turner, Melanie B MB; ,
Shared genetic susceptibility to ischemic stroke and coronary artery disease: a genome-wide analysis of common variants.
Stroke
Dichgans, Martin M; Malik, Rainer R; König, Inke R IR; Rosand, Jonathan J; Clarke, Robert R; Gretarsdottir, Solveig S; Thorleifsson, Gudmar G; Mitchell, Braxton D BD; Assimes, Themistocles L TL; Levi, Christopher C; O'Donnell, Christopher J CJ; Fornage, Myriam M; Thorsteinsdottir, Unnur U; Psaty, Bruce M BM; Hengstenberg, Christian C; Seshadri, Sudha S; Erdmann, Jeanette J; Bis, Joshua C JC; Peters, Annette A; Boncoraglio, Giorgio B GB; März, Winfried W; Meschia, James F JF; Kathiresan, Sekar S; Ikram, M Arfan MA; McPherson, Ruth R; Stefansson, Kari K; Sudlow, Cathie C; Reilly, Muredach P MP; Thompson, John R JR; Sharma, Pankaj P; Hopewell, Jemma C JC; Chambers, John C JC; Watkins, Hugh H; Rothwell, Peter M PM; Roberts, Robert R; Markus, Hugh S HS; Samani, Nilesh J NJ; Farrall, Martin M; Schunkert, Heribert H; , ; , ; , ; ,
Common genetic variants do not associate with CAD in familial hypercholesterolemia.
European Journal Of Human Genetics : Ejhg
van Iperen, Erik P A EP; Sivapalaratnam, Suthesh S; Boekholdt, S Matthijs SM; Hovingh, G Kees GK; Maiwald, Stephanie S; Tanck, Michael W MW; Soranzo, Nicole N; Stephens, Jonathan C JC; Sambrook, Jennifer G JG; Levi, Marcel M; Ouwehand, Willem H WH; Kastelein, John Jp JJ; Trip, Mieke D MD; Zwinderman, Aeilko H AH