Publications:

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Comprehensive proteogenomic characterization of early duodenal cancer reveals the carcinogenesis tracks of different subtypes.

Nature Communications

Li, Lingling L; Jiang, Dongxian D; Liu, Hui H; Guo, Chunmei C; Zhao, Rui R; Zhang, Qiao Q; Xu, Chen C; Qin, Zhaoyu Z; Feng, Jinwen J; Liu, Yang Y; Wang, Haixing H; Chen, Weijie W; Zhang, Xue X; Li, Bin B; Bai, Lin L; Tian, Sha S; Tan, Subei S; Yu, Zixiang Z; Chen, Lingli L; Huang, Jie J; Zhao, Jian-Yuan JY; Hou, Yingyong Y; Ding, Chen C

Publication Date: 2023-03-29

Variant appearance in text: C19orf80: R59W; rs2278426

PubMed Link: 36991000

Variant Present in the following documents:

• 41467_2023_37221_MOESM5_ESM.xlsx, sheet 3

View BVdb publication page

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Interaction between SIDT2 and ABCA1 Variants with Nutrients on HDL-c Levels in Mexican Adults.

Nutrients

León-Reyes, Guadalupe G; Argoty-Pantoja, Anna D AD; Rivera-Paredez, Berenice B; Hidalgo-Bravo, Alberto A; Flores, Yvonne N YN; Salmerón, Jorge J; Velázquez-Cruz, Rafael R

Publication Date: 2023-01-11

Variant appearance in text: ANGPTL8: Arg59Trp; rs2278426

PubMed Link: 36678241

Variant Present in the following documents:

• Main text
• nutrients-15-00370.pdf

View BVdb publication page

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Dynamic alteration of plasma levels of betatrophin in younger female onset obesity post acute moderate-intensity exercise training.

Saudi Journal Of Biological Sciences

Susanto, Hendra H; Sugiharto, ; Taufiq, Ahmad A; Pranoto, Adi A; Dwi Trijoyo Purnomo, Jerry J

Publication Date: 2023-02

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 36624736

Variant Present in the following documents:

• main.pdf

View BVdb publication page

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Genetic mimicry analysis reveals the specific lipases targeted by the ANGPTL3/ANGPTL8 complex and ANGPTL4.

Journal Of Lipid Research

Landfors, Fredrik F; Chorell, Elin E; Kersten, Sander S

Publication Date: 2022-11-10

Variant appearance in text: rs2278426

PubMed Link: 36372100

Variant Present in the following documents:

• Main text
• main.pdf
• mmc2.xlsx, sheet 1

View BVdb publication page

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Next-generation whole exome sequencing to delineate the genetic basis of primary congenital glaucoma.

Scientific Reports

Rauf, Bushra B; Khan, Shahid Y SY; Jiao, Xiaodong X; Irum, Bushra B; Ashfaq, Ramla R; Zehra, Mubashra M; Khan, Asma A AA; Naeem, Muhammad Asif MA; Shahzad, Mohsin M; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-10-14

Variant appearance in text: rs2278426

PubMed Link: 36241656

Variant Present in the following documents:

• 41598_2022_20939_MOESM14_ESM.xlsx, sheet 2

View BVdb publication page

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A genomic deletion encompassing CRYBB2-CRYBB2P1 is responsible for autosomal recessive congenital cataracts.

Human Genome Variation

Irum, Bushra B; Kabir, Firoz F; Shoshany, Nadav N; Khan, Shahid Y SY; Rauf, Bushra B; Naeem, Muhammad Asif MA; Qaiser, Tanveer A TA; Riazuddin, Sheikh S; Hejtmancik, J Fielding JF; Riazuddin, S Amer SA

Publication Date: 2022-09-08

Variant appearance in text: rs2278426

PubMed Link: 36075891

Variant Present in the following documents:

• 41439_2022_208_MOESM4_ESM.xlsx, sheet 2
• 41439_2022_208_MOESM3_ESM.xlsx, sheet 2
• 41439_2022_208_MOESM5_ESM.xlsx, sheet 2

View BVdb publication page

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Single-nucleotide polymorphisms as important risk factors of diabetes among Middle East population.

Human Genomics

Akhlaghipour, Iman I; Bina, Amir Reza AR; Mogharrabi, Mohammad Reza MR; Fanoodi, Ali A; Ebrahimian, Amir Reza AR; Khojasteh Kaffash, Soroush S; Babazadeh Baghan, Atefeh A; Khorashadizadeh, Mohammad Erfan ME; Taghehchian, Negin N; Moghbeli, Meysam M

Publication Date: 2022-04-02

Variant appearance in text: rs2278426

PubMed Link: 35366956

Variant Present in the following documents:

• Main text

View BVdb publication page

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APOE and KLF14 genetic variants are sex-specific for low high-density lipoprotein cholesterol identified by a genome-wide association study.

Genetics And Molecular Biology

Lee, Ying-Hui YH; Chang, Ya-Sian YS; Hsieh, Chih-Chang CC; Wang, Rong-Tsorng RT; Chang, Jan-Gowth JG; Chen, Chung-Jen CJ; Chang, Shun-Jen SJ

Publication Date: 2022

Variant appearance in text: rs2278426

PubMed Link: 35238325

Variant Present in the following documents:

• Main text
• 1415-4757-GMB-45-1-e20210280.pdf

View BVdb publication page

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Integrated molecular profiling of patient-derived ovarian cancer models identifies clinically relevant signatures and tumor vulnerabilities.

International Journal Of Cancer

Lupia, Michela M; Melocchi, Valentina V; Bizzaro, Francesca F; Lo Riso, Pietro P; Dama, Elisa E; Baronio, Micol M; Ranghiero, Alberto A; Barberis, Massimo M; Bernard, Loris L; Bertalot, Giovanni G; Giavazzi, Raffaella R; Testa, Giuseppe G; Bianchi, Fabrizio F; Cavallaro, Ugo U

Publication Date: 2022-07-15

Variant appearance in text: rs2278426

PubMed Link: 35218560

Variant Present in the following documents:

• IJC-151-240-s001.xlsx, sheet 7

View BVdb publication page

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SMAP is a pipeline for sample matching in proteogenomics.

Nature Communications

Li, Ling L; Niu, Mingming M; Erickson, Alyssa A; Luo, Jie J; Rowbotham, Kincaid K; Guo, Kai K; Huang, He H; Li, Yuxin Y; Jiang, Yi Y; Hur, Junguk J; Liu, Chunyu C; Peng, Junmin J; Wang, Xusheng X

Publication Date: 2022-02-08

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 35136070

Variant Present in the following documents:

• 41467_2022_28411_MOESM4_ESM.xlsx, sheet 1

View BVdb publication page

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Genetic Studies of Metabolic Syndrome in Arab Populations: A Systematic Review and Meta-Analysis.

Frontiers In Genetics

Al-Homedi, Zahrah Z; Afify, Nariman N; Memon, Mashal M; Alsafar, Habiba H; Tay, Guan G; Jelinek, Herbert F HF; Mousa, Mira M; Abu-Samra, Nadia N; Osman, Wael W

Publication Date: 2021

Variant appearance in text: rs2278426

PubMed Link: 34868209

Variant Present in the following documents:

• Table3.pdf

View BVdb publication page

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ANGPTL8 in metabolic homeostasis: more friend than foe?

Open Biology

Guo, Chang C; Wang, Chenxi C; Deng, Xia X; He, Jianqiang J; Yang, Ling L; Yuan, Guoyue G

Publication Date: 2021-09

Variant appearance in text: ANGPTL8: Arg59Trp

PubMed Link: 34582711

Variant Present in the following documents:

• Main text

View BVdb publication page

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Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8.

Journal Of Lipid Research

Sylvers-Davie, Kelli L KL; Segura-Roman, Ashley A; Salvi, Alicia M AM; Schache, Kylie J KJ; Davies, Brandon S J BSJ

Publication Date: 2021-08-27

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 34461133

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Angiopoietin-like 3 inhibition of endothelial lipase is not modulated by angiopoietin-like 8.

Journal Of Lipid Research

Sylvers-Davie, Kelli L KL; Segura-Roman, Ashley A; Salvi, Alicia M AM; Schache, Kylie J KJ; Davies, Brandon S J BSJ

Publication Date: 2021

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 34461133

Variant Present in the following documents:

• Main text
• main.pdf

View BVdb publication page

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Interaction between CETP polymorphism and dietary insulin index and load in relation to cardiovascular risk factors in diabetic adults.

Scientific Reports

Abaj, Faezeh F; Rafiee, Masoumeh M; Koohdani, Fariba F

Publication Date: 2021-08-05

Variant appearance in text: rs2278426

PubMed Link: 34354158

Variant Present in the following documents:

• 41598_2021_Article_95359.pdf

View BVdb publication page

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Association of NOS3-c.894G>T transversion with susceptibility to metabolic syndrome in Azar-cohort population: A case-control study and in silico analysis of the SNP molecular effects.

Iranian Journal Of Basic Medical Sciences

Seyedrezazadeh, Ensiyeh E; Faramarzi, Elnaz E; Bakhtiyari, Nasim N; Ansarin, Atefeh A; Gilani, Neda N; Amiri-Sadeghan, Amir A; Seyyedi, Maryam M; Ansarin, Khalil K; Aftabi, Younes Y

Publication Date: 2021-03

Variant appearance in text: rs2278426

PubMed Link: 33995953

Variant Present in the following documents:

• IJBMS-24-408.pdf

View BVdb publication page

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Disseminated Talaromyces marneffei Infection in a Non-HIV Infant With a Homozygous Private Variant of RELB.

Frontiers In Cellular And Infection Microbiology

Ding, Xiaofang X; Huang, Han H; Zhong, Lili L; Chen, Min M; Peng, Fang F; Zhang, Bing B; Cui, Xinyu X; Yang, Xiu-An XA

Publication Date: 2021

Variant appearance in text: C19orf80: R59W; rs2278426

PubMed Link: 33791233

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

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Genetic and Metabolic Determinants of Plasma Levels of ANGPTL8.

The Journal Of Clinical Endocrinology And Metabolism

Oldoni, Federico F; Bass, Kevin K; Kozlitina, Julia J; Hudson, Hannah H; Shihanian, Lisa M LM; Gusarova, Viktoria V; Cohen, Jonathan C JC; Hobbs, Helen H HH

Publication Date: 2021-05-13

Variant appearance in text: ANGPTL8: 175C>T; R59W; rs2278426

PubMed Link: 33619548

Variant Present in the following documents:

• Main text

View BVdb publication page

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Tractor uses local ancestry to enable the inclusion of admixed individuals in GWAS and to boost power.

Nature Genetics

Atkinson, Elizabeth G EG; Maihofer, Adam X AX; Kanai, Masahiro M; Martin, Alicia R AR; Karczewski, Konrad J KJ; Santoro, Marcos L ML; Ulirsch, Jacob C JC; Kamatani, Yoichiro Y; Okada, Yukinori Y; Finucane, Hilary K HK; Koenen, Karestan C KC; Nievergelt, Caroline M CM; Daly, Mark J MJ; Neale, Benjamin M BM

Publication Date: 2021-02

Variant appearance in text: rs2278426

PubMed Link: 33462486

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Interplay between Angiopoietin-Like Proteins and Adipose Tissue: Another Piece of the Relationship between Adiposopathy and Cardiometabolic Diseases?

International Journal Of Molecular Sciences

Bini, Simone S; D'Erasmo, Laura L; Di Costanzo, Alessia A; Minicocci, Ilenia I; Pecce, Valeria V; Arca, Marcello M

Publication Date: 2021-01-13

Variant appearance in text: ANGPTL8: R59W; rs2278426

PubMed Link: 33451033

Variant Present in the following documents:

• ijms-22-00742.pdf

View BVdb publication page

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The ANGPTL8 rs2278426 (C/T) Polymorphism Is Associated with Prediabetes and Type 2 Diabetes in a Han Chinese Population in Hebei Province.

International Journal Of Endocrinology

Hou, Guangsen G; Tang, Yong Y; Ren, Luping L; Guan, Yunpeng Y; Hou, Xiaoyu X; Song, Guangyao G

Publication Date: 2020

Variant appearance in text: ANGPTL8: R59W; rs2278426

PubMed Link: 33343659

Variant Present in the following documents:

• Main text
• IJE2020-1621239.pdf

View BVdb publication page

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Loss-of-function genomic variants highlight potential therapeutic targets for cardiovascular disease.

Nature Communications

Nielsen, Jonas B JB; Rom, Oren O; Surakka, Ida I; Graham, Sarah E SE; Zhou, Wei W; Roychowdhury, Tanmoy T; Fritsche, Lars G LG; Gagliano Taliun, Sarah A SA; Sidore, Carlo C; Liu, Yuhao Y; Gabrielsen, Maiken E ME; Skogholt, Anne Heidi AH; Wolford, Brooke B; Overton, William W; Zhao, Ying Y; Chen, Jin J; Zhang, He H; Hornsby, Whitney E WE; Acheampong, Akua A; Grooms, Austen A; Schaefer, Amanda A; Zajac, Gregory J M GJM; Villacorta, Luis L; Zhang, Jifeng J; Brumpton, Ben B; Løset, Mari M; Rai, Vivek V; Lundegaard, Pia R PR; Olesen, Morten S MS; Taylor, Kent D KD; Palmer, Nicholette D ND; Chen, Yii-Der YD; Choi, Seung H SH; Lubitz, Steven A SA; Ellinor, Patrick T PT; Barnes, Kathleen C KC; Daya, Michelle M; Rafaels, Nicholas N; Weiss, Scott T ST; Lasky-Su, Jessica J; Tracy, Russell P RP; Vasan, Ramachandran S RS; Cupples, L Adrienne LA; Mathias, Rasika A RA; Yanek, Lisa R LR; Becker, Lewis C LC; Peyser, Patricia A PA; Bielak, Lawrence F LF; Smith, Jennifer A JA; Aslibekyan, Stella S; Hidalgo, Bertha A BA; Arnett, Donna K DK; Irvin, Marguerite R MR; Wilson, James G JG; Musani, Solomon K SK; Correa, Adolfo A; Rich, Stephen S SS; Guo, Xiuqing X; Rotter, Jerome I JI; Konkle, Barbara A BA; Johnsen, Jill M JM; Ashley-Koch, Allison E AE; Telen, Marilyn J MJ; Sheehan, Vivien A VA; Blangero, John J; Curran, Joanne E JE; Peralta, Juan M JM; Montgomery, Courtney C; Sheu, Wayne H-H WH; Chung, Ren-Hua RH; Schwander, Karen K; Nouraie, Seyed M SM; Gordeuk, Victor R VR; Zhang, Yingze Y; Kooperberg, Charles C; Reiner, Alexander P AP; Jackson, Rebecca D RD; Bleecker, Eugene R ER; Meyers, Deborah A DA; Li, Xingnan X; Das, Sayantan S; Yu, Ketian K; LeFaive, Jonathon J; Smith, Albert A; Blackwell, Tom T; Taliun, Daniel D; Zollner, Sebastian S; Forer, Lukas L; Schoenherr, Sebastian S; Fuchsberger, Christian C; Pandit, Anita A; Zawistowski, Matthew M; Kheterpal, Sachin S; Brummett, Chad M CM; Natarajan, Pradeep P; Schlessinger, David D; Lee, Seunggeun S; Kang, Hyun Min HM; Cucca, Francesco F; Holmen, Oddgeir L OL; Åsvold, Bjørn O BO; Boehnke, Michael M; Kathiresan, Sekar S; Abecasis, Goncalo R GR; Chen, Y Eugene YE; Willer, Cristen J CJ; Hveem, Kristian K

Publication Date: 2020-12-18

Variant appearance in text: ANGPTL8: R59W; rs2278426

PubMed Link: 33339817

Variant Present in the following documents:

• 41467_2020_20086_MOESM4_ESM.xlsx, sheet 4
• 41467_2020_20086_MOESM4_ESM.xlsx, sheet 12

View BVdb publication page

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ANGPTL8 Gene Polymorphism rs2278426 Is Related to Carotid Intima-Media Thickness in T2DM.

Diabetes, Metabolic Syndrome And Obesity : Targets And Therapy

Guo, Chang C; Zhao, Li L; Ding, Yi Y; Zhao, Zhicong Z; Wang, Chenxi C; Li, Lian L; Cai, Zhensheng Z; Li, Yanyan Y; Xia, Hong H; Zhu, ZhuanZhuan Z; Yu, Fan F; Dai, Meiqing M; Deng, Xia X; Yuan, Guoyue G

Publication Date: 2020

Variant appearance in text: ANGPTL8: Arg59Trp; rs2278426

PubMed Link: 33244249

Variant Present in the following documents:

• Main text
• dmso-13-4519.pdf

View BVdb publication page

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Predictive values of ANGPTL8 on risk of all-cause mortality in diabetic patients: results from the REACTION Study.

Cardiovascular Diabetology

Zou, Huajie H; Xu, Yongping Y; Chen, Xi X; Yin, Ping P; Li, Danpei D; Li, Wenjun W; Xie, Junhui J; Shao, Shiying S; Liu, Liegang L; Yu, Xuefeng X

Publication Date: 2020-08-03

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 32746907

Variant Present in the following documents:

• Main text
• 12933_2020_Article_1103.pdf

View BVdb publication page

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The circulating ANGPTL8 levels show differences among novel subgroups of adult patients with diabetes and are associated with mortality in the subsequent 5 years.

Scientific Reports

Zou, Huajie H; Duan, Wu W; Zhang, Zeqing Z; Chen, Xi X; Lu, Puhan P; Yu, Xuefeng X

Publication Date: 2020-07-30

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 32732946

Variant Present in the following documents:

• Main text

View BVdb publication page

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Association of ANGPTL8 (Betatrophin) Gene Variants with Components of Metabolic Syndrome in Arab Adults.

Scientific Reports

Alenad, Amal A; Alenezi, Mona M MM; Alokail, Majed S MS; Wani, Kaiser K; Mohammed, Abdul Khader AK; Alnaami, Abdullah M AM; Sulimani, Maha M; Zargar, Seema S; Clerici, Mario M; Al-Daghri, Nasser M NM

Publication Date: 2020-04-21

Variant appearance in text: rs2278426

PubMed Link: 32317770

Variant Present in the following documents:

• Main text
• 41598_2020_Article_63850.pdf

View BVdb publication page

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Variants of Lipid-Related Genes in Adult Japanese Patients with Severe Hypertriglyceridemia.

Journal Of Atherosclerosis And Thrombosis

Matsunaga, Akira A; Nagashima, Mariko M; Yamagishi, Hideko H; Saku, Keijiro K

Publication Date: 2020-12-01

Variant appearance in text: ANGPTL8: 175C>T; R59W; rs2278426

PubMed Link: 32115487

Variant Present in the following documents:

• Main text
• jat-27-1264.pdf

View BVdb publication page

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YAP1 mediates survival of ALK-rearranged lung cancer cells treated with alectinib via pro-apoptotic protein regulation.

Nature Communications

Tsuji, Takahiro T; Ozasa, Hiroaki H; Aoki, Wataru W; Aburaya, Shunsuke S; Yamamoto Funazo, Tomoko T; Furugaki, Koh K; Yoshimura, Yasushi Y; Yamazoe, Masatoshi M; Ajimizu, Hitomi H; Yasuda, Yuto Y; Nomizo, Takashi T; Yoshida, Hironori H; Sakamori, Yuichi Y; Wake, Hiroaki H; Ueda, Mitsuyoshi M; Kim, Young Hak YH; Hirai, Toyohiro T

Publication Date: 2020-01-03

Variant appearance in text: C19orf80: R59W

PubMed Link: 31900393

Variant Present in the following documents:

• 41467_2019_13771_MOESM5_ESM.xlsx, sheet 1

View BVdb publication page

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GCH1 (rs841) polymorphism in the nitric oxide-forming pathway has protective effects on obstructive sleep apnea.

Scientific Reports

Sheikhi Kouhsar, Samaneh S; Bigdeli, Mohammadreza M; Shakiba, Yadollah Y; Sadeghniiat, Khosro K

Publication Date: 2019-12-09

Variant appearance in text: rs2278426

PubMed Link: 31819149

Variant Present in the following documents:

• 41598_2019_Article_55244.pdf

View BVdb publication page

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Histology and molecular biology studies on the expression and localization of angiopoietin-like protein 8 in human tissues.

Biomedical Reports

Akimoto, Naohiko N; Wada, Ryuichi R; Iwakiri, Katsuhiko K; Naito, Zenya Z

Publication Date: 2019-11

Variant appearance in text: ANGPTL8: Arg59Trp; rs2278426

PubMed Link: 31632669

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Korea Biobank Array: Design and Identification of Coding Variants Associated with Blood Biochemical Traits.

Scientific Reports

Moon, Sanghoon S; Kim, Young Jin YJ; Han, Sohee S; Hwang, Mi Yeong MY; Shin, Dong Mun DM; Park, Min Young MY; Lu, Yontao Y; Yoon, Kyungheon K; Jang, Hye-Mi HM; Kim, Yun Kyoung YK; Park, Tae-Joon TJ; Song, Dae Sub DS; Park, Jae Kyung JK; Lee, Jong-Eun JE; Kim, Bong-Jo BJ

Publication Date: 2019-02-04

Variant appearance in text: rs2278426

PubMed Link: 30718733

Variant Present in the following documents:

• Main text

View BVdb publication page

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Biological Pathways Leading From ANGPTL8 to Diabetes Mellitus-A Co-expression Network Based Analysis.

Frontiers In Physiology

Siddiqa, Amnah A; Cirillo, Elisa E; Tareen, Samar H K SHK; Ali, Amjad A; Kutmon, Martina M; Eijssen, Lars M T LMT; Ahmad, Jamil J; Evelo, Chris T CT; Coort, Susan L SL

Publication Date: 2018

Variant appearance in text: rs2278426

PubMed Link: 30627105

Variant Present in the following documents:

• Main text

View BVdb publication page

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Multiple genetic mutations caused by NKX6.3 depletion contribute to gastric tumorigenesis.

Scientific Reports

Yoon, Jung Hwan JH; Kim, Olga O; Eun, Jung Woo JW; Choi, Sung Sook SS; Ashktorab, Hassan H; Smoot, Duane T DT; Nam, Suk Woo SW; Park, Won Sang WS

Publication Date: 2018-12-04

Variant appearance in text: rs2278426

PubMed Link: 30514953

Variant Present in the following documents:

• 41598_2018_35733_MOESM2_ESM.xlsx, sheet 1

View BVdb publication page

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The negative effect of ANGPTL8 on HDL-mediated cholesterol efflux capacity.

Cardiovascular Diabetology

Luo, Mengdie M; Zhang, Ziyu Z; Peng, Yani Y; Wang, Shuai S; Peng, Daoquan D

Publication Date: 2018-11-08

Variant appearance in text: ANGPTL8: Arg59Trp

PubMed Link: 30409151

Variant Present in the following documents:

• 12933_2018_Article_785.pdf

View BVdb publication page

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Genetic Evidence Supporting the Role of the Calcium Channel, CACNA1S, in Tooth Cusp and Root Patterning.

Frontiers In Physiology

Laugel-Haushalter, Virginie V; Morkmued, Supawich S; Stoetzel, Corinne C; Geoffroy, Véronique V; Muller, Jean J; Boland, Anne A; Deleuze, Jean-François JF; Chennen, Kirsley K; Pitiphat, Waranuch W; Dollfus, Hélène H; Niederreither, Karen K; Bloch-Zupan, Agnès A; Pungchanchaikul, Patimaporn P

Publication Date: 2018

Variant appearance in text: rs2278426

PubMed Link: 30319441

Variant Present in the following documents:

• Table_7.xlsx, sheet 1

View BVdb publication page

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Association between rs2278426 (C/T) and rs892066 (C/G) variants of ANGPTL8 (betatrophin) and susceptibility to type2 diabetes mellitus.

Journal Of Clinical Laboratory Analysis

Ghasemi, Hassan H; Karimi, Jamshid J; Khodadadi, Iraj I; Saidijam, Massoud M; Tavilani, Heidar H

Publication Date: 2019-01

Variant appearance in text: rs2278426

PubMed Link: 30191588

Variant Present in the following documents:

• Main text

View BVdb publication page

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Deep-coverage whole genome sequences and blood lipids among 16,324 individuals.

Nature Communications

Natarajan, Pradeep P; Peloso, Gina M GM; Zekavat, Seyedeh Maryam SM; Montasser, May M; Ganna, Andrea A; Chaffin, Mark M; Khera, Amit V AV; Zhou, Wei W; Bloom, Jonathan M JM; Engreitz, Jesse M JM; Ernst, Jason J; O'Connell, Jeffrey R JR; Ruotsalainen, Sanni E SE; Alver, Maris M; Manichaikul, Ani A; Johnson, W Craig WC; Perry, James A JA; Poterba, Timothy T; Seed, Cotton C; Surakka, Ida L IL; Esko, Tonu T; Ripatti, Samuli S; Salomaa, Veikko V; Correa, Adolfo A; Vasan, Ramachandran S RS; Kellis, Manolis M; Neale, Benjamin M BM; Lander, Eric S ES; Abecasis, Goncalo G; Mitchell, Braxton B; Rich, Stephen S SS; Wilson, James G JG; Cupples, L Adrienne LA; Rotter, Jerome I JI; Willer, Cristen J CJ; Kathiresan, Sekar S; ,

Publication Date: 2018-08-23

Variant appearance in text: ANGPTL8: Arg59Trp; rs2278426

PubMed Link: 30140000

Variant Present in the following documents:

• 41467_2018_5747_MOESM1_ESM.pdf

View BVdb publication page

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Interaction between endothelial nitric oxide synthase rs1799983, cholesteryl ester-transfer protein rs708272 and angiopoietin-like protein 8 rs2278426 gene variants highly elevates the risk of type 2 diabetes mellitus and cardiovascular disease.

Cardiovascular Diabetology

El-Lebedy, Dalia D

Publication Date: 2018-07-04

Variant appearance in text: ANGPTL8: Arg59Trp; rs2278426

PubMed Link: 29973202

Variant Present in the following documents:

• Main text

View BVdb publication page

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Associations between circulating full-length angiopoietin-like protein 8 levels and severity of coronary artery disease in Chinese non-diabetic patients: a case-control study.

Cardiovascular Diabetology

Jiao, Xiaolu X; He, Jiqiang J; Yang, Yunyun Y; Yang, Song S; Li, Juan J; Qin, Yanwen Y

Publication Date: 2018-06-25

Variant appearance in text: ANGPTL8: R59W; rs2278426

PubMed Link: 29940978

Variant Present in the following documents:

• Main text
• 12933_2018_Article_736.pdf

View BVdb publication page

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Angiopoietin-like protein 3 (ANGPTL3) deficiency and familial combined hypolipidemia.

Journal Of Biomedical Research

Tarugi, Patrizia P; Bertolini, Stefano S; Calandra, Sebastiano S

Publication Date: 2019-04-22

Variant appearance in text: ANGPTL8: 175C>T; Arg59Trp; rs2278426

PubMed Link: 29752428

Variant Present in the following documents:

• Main text
• jbr-33-2-73.pdf

View BVdb publication page

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ANGPTL8: An Important Regulator in Metabolic Disorders.

Frontiers In Endocrinology

Luo, Mengdie M; Peng, Daoquan D

Publication Date: 2018

Variant appearance in text: ANGPTL8: R59W; rs2278426

PubMed Link: 29719529

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic architecture of lipid traits in the Hispanic community health study/study of Latinos.

Lipids In Health And Disease

Graff, Mariaelisa M; Emery, Leslie S LS; Justice, Anne E AE; Parra, Esteban E; Below, Jennifer E JE; Palmer, Nicholette D ND; Gao, Chuan C; Duan, Qing Q; Valladares-Salgado, Adan A; Cruz, Miguel M; Morrison, Alanna C AC; Boerwinkle, Eric E; Whitsel, Eric A EA; Kooperberg, Charles C; Reiner, Alex A; Li, Yun Y; Rodriguez, Carlos Jose CJ; Talavera, Gregory A GA; Langefeld, Carl D CD; Wagenknecht, Lynne E LE; Norris, Jill M JM; Taylor, Kent D KD; Papanicolaou, George G; Kenny, Eimear E; Loos, Ruth J F RJF; Chen, Yii-Der Ida YI; Laurie, Cathy C; Sofer, Tamar T; North, Kari E KE

Publication Date: 2017-10-12

Variant appearance in text: rs2278426

PubMed Link: 29025430

Variant Present in the following documents:

• Main text
• 12944_2017_Article_591.pdf

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Multiple phenotype association tests using summary statistics in genome-wide association studies.

Biometrics

Liu, Zhonghua Z; Lin, Xihong X

Publication Date: 2018-03

Variant appearance in text: rs2278426

PubMed Link: 28653391

Variant Present in the following documents:

• Main text

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Genetic determinants of inherited susceptibility to hypercholesterolemia - a comprehensive literature review.

Lipids In Health And Disease

Paththinige, C S CS; Sirisena, N D ND; Dissanayake, Vhw V

Publication Date: 2017-06-02

Variant appearance in text: ANGPTL8: Arg59Trp; rs2278426

PubMed Link: 28577571

Variant Present in the following documents:

• Main text
• 12944_2017_Article_488.pdf

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Increased ANGPTL3, 4 and ANGPTL8/betatrophin expression levels in obesity and T2D.

Lipids In Health And Disease

Abu-Farha, Mohamed M; Al-Khairi, Irina I; Cherian, Preethi P; Chandy, Betty B; Sriraman, Devarajan D; Alhubail, Asma A; Al-Refaei, Faisal F; AlTerki, Abdulmohsen A; Abubaker, Jehad J

Publication Date: 2016-10-13

Variant appearance in text: rs2278426

PubMed Link: 27733177

Variant Present in the following documents:

• Main text

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The Rise and the Fall of Betatrophin/ANGPTL8 as an Inducer of β-Cell Proliferation.

Journal Of Diabetes Research

Abu-Farha, Mohamed M; Al Madhoun, Ashraf A; Abubaker, Jehad J

Publication Date: 2016

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 27672665

Variant Present in the following documents:

• Main text
• JDR2016-4860595.pdf

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The chronological sequence of somatic mutations in early gastric carcinogenesis inferred from multiregion sequencing of gastric adenomas.

Oncotarget

Lim, Chul-Hyun CH; Cho, Yu Kyung YK; Kim, Sang Woo SW; Choi, Myung-Gyu MG; Rhee, Je-Keun JK; Chung, Yeun-Jun YJ; Lee, Sug-Hyung SH; Kim, Tae-Min TM

Publication Date: 2016-06-28

Variant appearance in text: C19orf80: R59W

PubMed Link: 27175599

Variant Present in the following documents:

• oncotarget-07-39758-s006.xlsx, sheet 1

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The Arg59Trp variant in ANGPTL8 (betatrophin) is associated with total and HDL-cholesterol in American Indians and Mexican Americans and differentially affects cleavage of ANGPTL3.

Molecular Genetics And Metabolism

Hanson, Robert L RL; Leti, Fatjon F; Tsinajinnie, Darwin D; Kobes, Sayuko S; Puppala, Sobha S; Curran, Joanne E JE; Almasy, Laura L; Lehman, Donna M DM; Blangero, John J; Duggirala, Ravindranath R; DiStefano, Johanna K JK

Publication Date: 2016-06

Variant appearance in text: ANGPTL8: R59W; rs2278426

PubMed Link: 27117576

Variant Present in the following documents:

• Main text

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The ANGPTL3-4-8 model, a molecular mechanism for triglyceride trafficking.

Open Biology

Zhang, Ren R

Publication Date: 2016-04

Variant appearance in text: rs2278426

PubMed Link: 27053679

Variant Present in the following documents:

• Main text

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ANGPTL8/Betatrophin R59W variant is associated with higher glucose level in non-diabetic Arabs living in Kuwaits.

Lipids In Health And Disease

Abu-Farha, Mohamed M; Melhem, Motasem M; Abubaker, Jehad J; Behbehani, Kazem K; Alsmadi, Osama O; Elkum, Naser N

Publication Date: 2016-02-11

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 26864934

Variant Present in the following documents:

• Main text

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Circulating angiopoietin-like protein 8 (betatrophin) association with HsCRP and metabolic syndrome.

Cardiovascular Diabetology

Abu-Farha, Mohamed M; Abubaker, Jehad J; Al-Khairi, Irina I; Cherian, Preethi P; Noronha, Fiona F; Kavalakatt, Sina S; Khadir, Abdelkrim A; Behbehani, Kazem K; Alarouj, Monira M; Bennakhi, Abdullah A; Elkum, Naser N

Publication Date: 2016-02-05

Variant appearance in text: ANGPTL8: R59W

PubMed Link: 26850725

Variant Present in the following documents:

• Main text
• 12933_2016_Article_346.pdf

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Meta-analysis of lipid-traits in Hispanics identifies novel loci, population-specific effects, and tissue-specific enrichment of eQTLs.

Scientific Reports

Below, Jennifer E JE; Parra, Esteban J EJ; Gamazon, Eric R ER; Torres, Jason J; Krithika, S S; Candille, Sophie S; Lu, Yingchang Y; Manichakul, Ani A; Peralta-Romero, Jesus J; Duan, Qing Q; Li, Yun Y; Morris, Andrew P AP; Gottesman, Omri O; Bottinger, Erwin E; Wang, Xin-Qun XQ; Taylor, Kent D KD; Ida Chen, Y-D YD; Rotter, Jerome I JI; Rich, Stephen S SS; Loos, Ruth J F RJ; Tang, Hua H; Cox, Nancy J NJ; Cruz, Miguel M; Hanis, Craig L CL; Valladares-Salgado, Adan A

Publication Date: 2016-01-19

Variant appearance in text: rs2278426

PubMed Link: 26780889

Variant Present in the following documents:

• Main text

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