Publications:

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Amyposomes, a nanotechnological chaperone with anti-amyloidogenic activity.

Annals Of Medicine

Re, Francesca F; Giorgetti, Sofia S; Biondi, Barbara B; Scapin, Stefano S; Mantegazza, Francesco F; Cassina, Valeria V; Sesana, Silvia Maria SM; Rizzi, Laura L; Eberini, Ivano I; Palazzolo, Luca L; Beeg, Marten M; Gobbi, Marco M; Sardina, Marco M; Masserini, Massimo M

Publication Date: 2023-12

Variant appearance in text: SSA: S52P

PubMed Link: 37143345

Variant Present in the following documents:

• Main text
• IANN_55_2205659.pdf

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Development of a Highly Potent Transthyretin Amyloidogenesis Inhibitor: Design, Synthesis, and Evaluation.

Journal Of Medicinal Chemistry

Pinheiro, Francisca F; Pallarès, Irantzu I; Peccati, Francesca F; Sánchez-Morales, Adrià A; Varejão, Nathalia N; Bezerra, Filipa F; Ortega-Alarcon, David D; Gonzalez, Danilo D; Osorio, Marcelo M; Navarro, Susanna S; Velázquez-Campoy, Adrián A; Almeida, Maria Rosário MR; Reverter, David D; Busqué, Félix F; Alibés, Ramon R; Sodupe, Mariona M; Ventura, Salvador S

Publication Date: 2022-11-10

Variant appearance in text: SSA: Ser52Pro

PubMed Link: 36306808

Variant Present in the following documents:

• jm2c01195.pdf

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The Transthyretin/Oleuropein Aglycone Complex: A New Tool against TTR Amyloidosis.

Pharmaceuticals (Basel, Switzerland)

Bemporad, Francesco F; Leri, Manuela M; Ramazzotti, Matteo M; Stefani, Massimo M; Bucciantini, Monica M

Publication Date: 2022-02-23

Variant appearance in text: SSA: Ser52Pro

PubMed Link: 35337074

Variant Present in the following documents:

• pharmaceuticals-15-00277.pdf

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Disease-associated mutations impacting BC-loop flexibility trigger long-range transthyretin tetramer destabilization and aggregation.

The Journal Of Biological Chemistry

Esperante, Sebastián A SA; Varejāo, Nathalia N; Pinheiro, Francisca F; Sant'Anna, Ricardo R; Luque-Ortega, Juan Román JR; Alfonso, Carlos C; Sora, Valentina V; Papaleo, Elena E; Rivas, Germán G; Reverter, David D; Ventura, Salvador S

Publication Date: 2021-09

Variant appearance in text: SSA: S52P

PubMed Link: 34343569

Variant Present in the following documents:

• Main text
• main.pdf

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A serine protease secreted from Bacillus subtilis cleaves human plasma transthyretin to generate an amyloidogenic fragment.

Communications Biology

Peterle, Daniele D; Pontarollo, Giulia G; Spada, Stefano S; Brun, Paola P; Palazzi, Luana L; Sokolov, Alexej V AV; Spolaore, Barbara B; Polverino de Laureto, Patrizia P; Vasilyev, Vadim B VB; Castagliuolo, Ignazio I; De Filippis, Vincenzo V

Publication Date: 2020-12-11

Variant appearance in text: SSA: Ser52Pro

PubMed Link: 33311636

Variant Present in the following documents:

• Main text
• 42003_2020_Article_1493.pdf

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A molecular mechanism for transthyretin amyloidogenesis.

Nature Communications

Yee, Ai Woon AW; Aldeghi, Matteo M; Blakeley, Matthew P MP; Ostermann, Andreas A; Mas, Philippe J PJ; Moulin, Martine M; de Sanctis, Daniele D; Bowler, Matthew W MW; Mueller-Dieckmann, Christoph C; Mitchell, Edward P EP; Haertlein, Michael M; de Groot, Bert L BL; Boeri Erba, Elisabetta E; Forsyth, V Trevor VT

Publication Date: 2019-02-25

Variant appearance in text: SSA: S52P

PubMed Link: 30804345

Variant Present in the following documents:

• Main text
• 41467_2019_Article_8609.pdf

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A FTIR microspectroscopy study of the structural and biochemical perturbations induced by natively folded and aggregated transthyretin in HL-1 cardiomyocytes.

Scientific Reports

Ami, Diletta D; Mereghetti, Paolo P; Leri, Manuela M; Giorgetti, Sofia S; Natalello, Antonino A; Doglia, Silvia Maria SM; Stefani, Massimo M; Bucciantini, Monica M

Publication Date: 2018-08-21

Variant appearance in text: SSA: Ser52Pro

PubMed Link: 30131519

Variant Present in the following documents:

• 41598_2018_Article_30995.pdf

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(99m)Tc-DPD uptake reflects amyloid fibril composition in hereditary transthyretin amyloidosis.

Upsala Journal Of Medical Sciences

Pilebro, Björn B; Suhr, Ole B OB; Näslund, Ulf U; Westermark, Per P; Lindqvist, Per P; Sundström, Torbjörn T

Publication Date: 2016

Variant appearance in text: SSA: Ser52Pro

PubMed Link: 26849806

Variant Present in the following documents:

• Main text
• iups-121-17.pdf

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