Publications:

Oncogenic CALR mutant C-terminus mediates dual binding to the thrombopoietin receptor triggering complex dimerization and activation.

Nature Communications

Papadopoulos, Nicolas N; Nédélec, Audrey A; Derenne, Allison A; Şulea, Teodor Asvadur TA; Pecquet, Christian C; Chachoua, Ilyas I; Vertenoeil, Gaëlle G; Tilmant, Thomas T; Petrescu, Andrei-Jose AJ; Mazzucchelli, Gabriel G; Iorga, Bogdan I BI; Vertommen, Didier D; Constantinescu, Stefan N SN

Publication Date: 2023-04-05

Variant appearance in text: CALR: D135L

PubMed Link: 37019903

Variant Present in the following documents:

• 41467_2023_37277_MOESM1_ESM.pdf
• 41467_2023_Article_37277.pdf

View BVdb publication page

Defining the requirements for the pathogenic interaction between mutant calreticulin and MPL in MPN.

Blood

Elf, Shannon S; Abdelfattah, Nouran S NS; Baral, April J AJ; Beeson, Danielle D; Rivera, Jeanne F JF; Ko, Amy A; Florescu, Natalie N; Birrane, Gabriel G; Chen, Edwin E; Mullally, Ann A

Publication Date: 2018-02-15

Variant appearance in text: CALR: D135L

PubMed Link: 29288169

Variant Present in the following documents:

• Main text

View BVdb publication page

Novel molecular mechanism of cellular transformation by a mutant molecular chaperone in myeloproliferative neoplasms.

Cancer Science

Araki, Marito M; Komatsu, Norio N

Publication Date: 2017-10

Variant appearance in text: CALR: D135L

PubMed Link: 28741795

Variant Present in the following documents:

• Main text
• CAS-108-1907.pdf

View BVdb publication page