Publications:

Targeting the histone H3 lysine 79 methyltransferase DOT1L in MLL-rearranged leukemias.

Journal Of Hematology & Oncology

Yi, Yan Y; Ge, Shenglei S

Publication Date: 2022-03-24

Variant appearance in text: DOT1L: R278E

PubMed Link: 35331314

Variant Present in the following documents:

• Main text
• 13045_2022_Article_1251.pdf

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DOT1L activity in leukemia cells requires interaction with ubiquitylated H2B that promotes productive nucleosome binding.

Cell Reports

Spangler, Cathy J CJ; Yadav, Satya P SP; Li, Dongxu D; Geil, Carinne N CN; Smith, Charlotte B CB; Wang, Gang Greg GG; Lee, Tae-Hee TH; McGinty, Robert K RK

Publication Date: 2022-02-15

Variant appearance in text: DOT1L: R278E

PubMed Link: 35172132

Variant Present in the following documents:

• Main text
• nihms-1781192.pdf

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