Apolipoprotein E (APOE) Haplotypes in Healthy Subjects from Worldwide Macroareas: A Population Genetics Perspective for Cardiovascular Disease, Neurodegeneration, and Dementia.
Current Issues In Molecular Biology
Abondio, Paolo P; Bruno, Francesco F; Luiselli, Donata D
Deep learning-based polygenic risk analysis for Alzheimer's disease prediction.
Communications Medicine
Zhou, Xiaopu X; Chen, Yu Y; Ip, Fanny C F FCF; Jiang, Yuanbing Y; Cao, Han H; Lv, Ge G; Zhong, Huan H; Chen, Jiahang J; Ye, Tao T; Chen, Yuewen Y; Zhang, Yulin Y; Ma, Shuangshuang S; Lo, Ronnie M N RMN; Tong, Estella P S EPS; , ; Mok, Vincent C T VCT; Kwok, Timothy C Y TCY; Guo, Qihao Q; Mok, Kin Y KY; Shoai, Maryam M; Hardy, John J; Chen, Lei L; Fu, Amy K Y AKY; Ip, Nancy Y NY
Network expansion of genetic associations defines a pleiotropy map of human cell biology.
Nature Genetics
Barrio-Hernandez, Inigo I; Schwartzentruber, Jeremy J; Shrivastava, Anjali A; Del-Toro, Noemi N; Gonzalez, Asier A; Zhang, Qian Q; Mountjoy, Edward E; Suveges, Daniel D; Ochoa, David D; Ghoussaini, Maya M; Bradley, Glyn G; Hermjakob, Henning H; Orchard, Sandra S; Dunham, Ian I; Anderson, Carl A CA; Porras, Pablo P; Beltrao, Pedro P
Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review.
Frontiers In Nutrition
Pérez-Beltrán, Yolanda E YE; Rivera-Iñiguez, Ingrid I; Gonzalez-Becerra, Karina K; Pérez-Naitoh, Naomi N; Tovar, Juscelino J; Sáyago-Ayerdi, Sonia G SG; Mendivil, Edgar J EJ
Association between clinical symptoms and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia.
Association between clinical symptoms and apolipoprotein A1 or apolipoprotein B levels is regulated by apolipoprotein E variant rs429358 in patients with chronic schizophrenia.
Genome-wide analysis identifies a novel LINC-PINT splice variant associated with vascular amyloid pathology in Alzheimer's disease.
Acta Neuropathologica Communications
Reddy, Joseph S JS; Allen, Mariet M; Ho, Charlotte C G CCG; Oatman, Stephanie R SR; İş, Özkan Ö; Quicksall, Zachary S ZS; Wang, Xue X; Jin, Jiangli J; Patel, Tulsi A TA; Carnwath, Troy P TP; Nguyen, Thuy T TT; Malphrus, Kimberly G KG; Lincoln, Sarah J SJ; Carrasquillo, Minerva M MM; Crook, Julia E JE; Kanekiyo, Takahisa T; Murray, Melissa E ME; Bu, Guojun G; Dickson, Dennis W DW; Ertekin-Taner, Nilüfer N
Association Between Episodic Memory and Genetic Risk Factors for Alzheimer's Disease in South Asians from the Longitudinal Aging Study in India-Diagnostic Assessment of Dementia (LASI-DAD).
Journal Of The American Geriatrics Society
Smith, Jennifer A JA; Zhao, Wei W; Yu, Miao M; Rumfelt, Kalee E KE; Moorjani, Priya P; Ganna, Andrea A; Dey, Aparajit B AB; Lee, Jinkook J; Kardia, Sharon L R SLR
Genetic analysis of hsCRP in American Indians: The Strong Heart Family Study.
Plos One
Best, Lyle G LG; Balakrishnan, Poojitha P; Cole, Shelley A SA; Haack, Karin K; Kocarnik, Jonathan M JM; Pankratz, Nathan N; Anderson, Matthew Z MZ; Franceschini, Nora N; Howard, Barbara V BV; Lee, Elisa T ET; North, Kari E KE; Umans, Jason G JG; Yracheta, Joseph M JM; Navas-Acien, Ana A; Voruganti, V Saroja VS
APOE Promoter Polymorphism-219T/G is an Effect Modifier of the Influence of APOE ε4 on Alzheimer's Disease Risk in a Multiracial Sample.
Journal Of Clinical Medicine
Choi, Kyu Yeong KY; Lee, Jang Jae JJ; Gunasekaran, Tamil Iniyan TI; Kang, Sarang S; Lee, Wooje W; Jeong, Jangho J; Lim, Ho Jae HJ; Zhang, Xiaoling X; Zhu, Congcong C; Won, So-Yoon SY; Choi, Yu Yong YY; Seo, Eun Hyun EH; Lee, Seok Cheol SC; Gim, Jungsoo J; Chung, Ji Yeon JY; Chong, Ari A; Byun, Min Soo MS; Seo, Sujin S; Ko, Pan-Woo PW; Han, Ji-Won JW; McLean, Catriona C; Farrell, John J; Lunetta, Kathryn L KL; Miyashita, Akinori A; Hara, Norikazu N; Won, Sungho S; Choi, Seong-Min SM; Ha, Jung-Min JM; Jeong, Jee Hyang JH; Kuwano, Ryozo R; Song, Min Kyung MK; An, Seong Soo A SSA; Lee, Young Min YM; Park, Kyung Won KW; Lee, Ho-Won HW; Choi, Seong Hye SH; Rhee, Sangmyung S; Song, Woo Keun WK; Lee, Jung Sup JS; Mayeux, Richard R; Haines, Jonathan L JL; Pericak-Vance, Margaret A MA; Choo, I L Han ILH; Nho, Kwangsik K; Kim, Ki-Woong KW; Lee, Dong Young DY; Kim, SangYun S; Kim, Byeong C BC; Kim, Hoowon H; Jun, Gyungah R GR; Schellenberg, Gerard D GD; Ikeuchi, Takeshi T; Farrer, Lindsay A LA; Lee, Kun Ho KH; Neuroimaging Initative, Alzheimer's Disease AD
Non-coding variability at the APOE locus contributes to the Alzheimer's risk.
Nature Communications
Zhou, Xiaopu X; Chen, Yu Y; Mok, Kin Y KY; Kwok, Timothy C Y TCY; Mok, Vincent C T VCT; Guo, Qihao Q; Ip, Fanny C FC; Chen, Yuewen Y; Mullapudi, Nandita N; , ; Giusti-Rodríguez, Paola P; Sullivan, Patrick F PF; Hardy, John J; Fu, Amy K Y AKY; Li, Yun Y; Ip, Nancy Y NY
Apolipoprotein E-C1-C4-C2 gene cluster region and inter-individual variation in plasma lipoprotein levels: a comprehensive genetic association study in two ethnic groups.
Plos One
Pirim, Dilek D; Radwan, Zaheda H ZH; Wang, Xingbin X; Niemsiri, Vipavee V; Hokanson, John E JE; Hamman, Richard F RF; Feingold, Eleanor E; Bunker, Clareann H CH; Demirci, F Yesim FY; Kamboh, M Ilyas MI
Association of apolipoprotein E gene polymorphisms with blood lipids and their interaction with dietary factors.
Lipids In Health And Disease
Shatwan, Israa M IM; Winther, Kristian Hillert KH; Ellahi, Basma B; Elwood, Peter P; Ben-Shlomo, Yoav Y; Givens, Ian I; Rayman, Margaret P MP; Lovegrove, Julie A JA; Vimaleswaran, Karani S KS
Apolipoprotein E gene polymorphism modifies fasting total cholesterol concentrations in response to replacement of dietary saturated with monounsaturated fatty acids in adults at moderate cardiovascular disease risk.
Lipids In Health And Disease
Shatwan, Israa M IM; Weech, Michelle M; Jackson, Kim G KG; Lovegrove, Julie A JA; Vimaleswaran, Karani S KS
Hidden heterogeneity in Alzheimer's disease: Insights from genetic association studies and other analyses.
Experimental Gerontology
Yashin, Anatoliy I AI; Fang, Fang F; Kovtun, Mikhail M; Wu, Deqing D; Duan, Matt M; Arbeev, Konstantin K; Akushevich, Igor I; Kulminski, Alexander A; Culminskaya, Irina I; Zhbannikov, Ilya I; Yashkin, Arseniy A; Stallard, Eric E; Ukraintseva, Svetlana S
An integrative genomics approach identifies novel pathways that influence candidaemia susceptibility.
Plos One
Matzaraki, Vasiliki V; Gresnigt, Mark S MS; Jaeger, Martin M; Ricaño-Ponce, Isis I; Johnson, Melissa D MD; Oosting, Marije M; Franke, Lude L; Withoff, Sebo S; Perfect, John R JR; Joosten, Leo A B LAB; Kullberg, Bart Jan BJ; van de Veerdonk, Frank L FL; Jonkers, Iris I; Li, Yang Y; Wijmenga, Cisca C; Netea, Mihai G MG; Kumar, Vinod V
Genetic variants determining survival and fertility in an adverse African environment: a population-based large-scale candidate gene association study.
Aging
Koopman, Jacob J E JJ; Pijpe, Jeroen J; Böhringer, Stefan S; van Bodegom, David D; Eriksson, Ulrika K UK; Sanchez-Faddeev, Hernando H; Ziem, Juventus B JB; Zwaan, Bas B; Slagboom, P Eline PE; de Knijff, Peter P; Westendorp, Rudi G J RG
Multiple genetic imaging study of the association between cholesterol metabolism and brain functional alterations in individuals with risk factors for Alzheimer's disease.
Comprehensive evaluation of the association of APOE genetic variation with plasma lipoprotein traits in U.S. whites and African blacks.
Plos One
Radwan, Zaheda H ZH; Wang, Xingbin X; Waqar, Fahad F; Pirim, Dilek D; Niemsiri, Vipavee V; Hokanson, John E JE; Hamman, Richard F RF; Bunker, Clareann H CH; Barmada, M Michael MM; Demirci, F Yesim FY; Kamboh, M Ilyas MI
Genetic variation and reproductive timing: African American women from the Population Architecture using Genomics and Epidemiology (PAGE) Study.
Plos One
Spencer, Kylee L KL; Malinowski, Jennifer J; Carty, Cara L CL; Franceschini, Nora N; Fernández-Rhodes, Lindsay L; Young, Alicia A; Cheng, Iona I; Ritchie, Marylyn D MD; Haiman, Christopher A CA; Wilkens, Lynne L; Chunyuanwu, ; Matise, Tara C TC; Carlson, Christopher S CS; Brennan, Kathleen K; Park, Amy A; Rajkovic, Aleksandar A; Hindorff, Lucia A LA; Buyske, Steven S; Crawford, Dana C DC
Multi-ethnic analysis of lipid-associated loci: the NHLBI CARe project.
Plos One
Musunuru, Kiran K; Romaine, Simon P R SP; Lettre, Guillaume G; Wilson, James G JG; Volcik, Kelly A KA; Tsai, Michael Y MY; Taylor, Herman A HA; Schreiner, Pamela J PJ; Rotter, Jerome I JI; Rich, Stephen S SS; Redline, Susan S; Psaty, Bruce M BM; Papanicolaou, George J GJ; Ordovas, Jose M JM; Liu, Kiang K; Krauss, Ronald M RM; Glazer, Nicole L NL; Gabriel, Stacey B SB; Fornage, Myriam M; Cupples, L Adrienne LA; Buxbaum, Sarah G SG; Boerwinkle, Eric E; Ballantyne, Christie M CM; Kathiresan, Sekar S; Rader, Daniel J DJ
Associations between APOE variants and metabolic traits and the impact of psychological stress.
Plos One
Iqbal Kring, Sofia I SI; Barefoot, John J; Brummett, Beverly H BH; Boyle, Stephen H SH; Siegler, Ilene C IC; Toubro, Søren S; Hansen, Torben T; Astrup, Arne A; Pedersen, Oluf O; Williams, Redford B RB; Sørensen, Thorkild I A TI
Impact of psychological stress on the associations between apolipoprotein E variants and metabolic traits: findings in an American sample of caregivers and controls.
Psychosomatic Medicine
Kring, Sofia I Iqbal SI; Brummett, Beverly H BH; Barefoot, John J; Garrett, Melanie E ME; Ashley-Koch, Allison E AE; Boyle, Stephen H SH; Siegler, Ilene C IC; Sørensen, Thorkild I A TI; Williams, Redford B RB