The relationship between retinal layers and brain areas in asymptomatic first-degree relatives of sporadic forms of Alzheimer's disease: an exploratory analysis.
Alzheimer'S Research & Therapy
López-Cuenca, Inés I; Marcos-Dolado, Alberto A; Yus-Fuertes, Miguel M; Salobrar-García, Elena E; Elvira-Hurtado, Lorena L; Fernández-Albarral, José A JA; Salazar, Juan J JJ; Ramírez, Ana I AI; Sánchez-Puebla, Lidia L; Fuentes-Ferrer, Manuel Enrique ME; Barabash, Ana A; Ramírez-Toraño, Federico F; Gil-Martínez, Lidia L; Arrazola-García, Juan J; Gil, Pedro P; de Hoz, Rosa R; Ramírez, José M JM
Mapping the genetic landscape of early-onset Alzheimer's disease in a cohort of 36 families.
Alzheimer'S Research & Therapy
Mol, Merel O MO; van der Lee, Sven J SJ; Hulsman, Marc M; Pijnenburg, Yolande A L YAL; Scheltens, Phillip P; , ; Seelaar, Harro H; van Swieten, John C JC; Kaat, Laura Donker LD; Holstege, Henne H; van Rooij, Jeroen G J JGJ
Accounting for population structure in genetic studies of cystic fibrosis.
Hgg Advances
Kingston, Hanley H; Stilp, Adrienne M AM; Gordon, William W; Broome, Jai J; Gogarten, Stephanie M SM; Ling, Hua H; Barnard, John J; Dugan-Perez, Shannon S; Ellinor, Patrick T PT; Gabriel, Stacey S; Germer, Soren S; Gibbs, Richard A RA; Gupta, Namrata N; Rice, Kenneth K; Smith, Albert V AV; Zody, Michael C MC; , ; , ; Blackman, Scott M SM; Cutting, Garry G; Knowles, Michael R MR; Zhou, Yi-Hui YH; Rosenfeld, Margaret M; Gibson, Ronald L RL; Bamshad, Michael M; Fohner, Alison A; Blue, Elizabeth E EE
Publication Date: 2022-07-14
Variant appearance in text: APOE: 388T>C; Cys130Arg
Italian Case Report with a Double Mutation in PSEN1 (K311R and E318G).
Neurology International
Bisceglia, Paola P; Lo Vecchio, Filomena F; Latino, Raffaela Rita RR; Gravina, Carolina C; Urbano, Maria M; la Torre, Annamaria A; Desina, Gaetano G; Greco, Antonio A; Leone, Maurizio M; Antonioni, Annibale A
Characterization of Retinal Drusen in Subjects at High Genetic Risk of Developing Sporadic Alzheimer's Disease: An Exploratory Analysis.
Journal Of Personalized Medicine
López-Cuenca, Inés I; Salobrar-García, Elena E; Gil-Salgado, Inés I; Sánchez-Puebla, Lidia L; Elvira-Hurtado, Lorena L; Fernández-Albarral, José A JA; Ramírez-Toraño, Federico F; Barabash, Ana A; de Frutos-Lucas, Jaisalmer J; Salazar, Juan J JJ; Ramírez, José M JM; Ramírez, Ana I AI; de Hoz, Rosa R
Concussion-Associated Polygenic Profiles of Elite Male Rugby Athletes.
Genes
Antrobus, Mark R MR; Brazier, Jon J; Callus, Peter C PC; Herbert, Adam J AJ; Stebbings, Georgina K GK; Khanal, Praval P; Day, Stephen H SH; Kilduff, Liam P LP; Bennett, Mark A MA; Erskine, Robert M RM; Raleigh, Stuart M SM; Collins, Malcolm M; Pitsiladis, Yannis P YP; Heffernan, Shane M SM; Williams, Alun G AG
Cerebrospinal Fluid Neurofilament Light Predicts Risk of Dementia Onset in Cognitively Healthy Individuals and Rate of Cognitive Decline in Mild Cognitive Impairment: A Prospective Longitudinal Study.
Biomedicines
Dhiman, Kunal K; Villemagne, Victor L VL; Fowler, Christopher C; Bourgeat, Pierrick P; Li, Qiao-Xin QX; Collins, Steven S; Bush, Ashley I AI; Rowe, Christopher C CC; Masters, Colin L CL; Ames, David D; Blennow, Kaj K; Zetterberg, Henrik H; Martins, Ralph N RN; Gupta, Veer V
Long-term low-dose acetylsalicylic use shows protective potential for the development of both vascular dementia and Alzheimer's disease in patients with coronary heart disease but not in other individuals from the general population: results from two large cohort studies.
Alzheimer'S Research & Therapy
Nguyen, Thi Ngoc Mai TNM; Chen, Li-Ju LJ; Trares, Kira K; Stocker, Hannah H; Holleczek, Bernd B; Beyreuther, Konrad K; Brenner, Hermann H; Schöttker, Ben B
Electroacupuncture for Cancer-Related Cognitive Impairment: A Clinical Feasibility Study.
Integrative Cancer Therapies
Lyu, Yee Ran YR; Lee, Hye-Yoon HY; Park, Hyo-Ju HJ; Kwon, O-Jin OJ; Kim, Ae-Ran AR; Jung, In Chul IC; Park, Yang-Chun YC; Cho, Jung-Hyo JH; Kim, Jung-Eun JE; Kim, Mikyung M; Lee, Jun-Hwan JH; Kim, Joo-Hee JH
The genetic architecture of Alzheimer disease risk in the Ohio and Indiana Amish.
Hgg Advances
Osterman, Michael D MD; Song, Yeunjoo E YE; Adams, Larry D LD; Laux, Renee A RA; Caywood, Laura J LJ; Prough, Michael B MB; Clouse, Jason E JE; Herington, Sharlene D SD; Slifer, Susan H SH; Lynn, Audrey A; Fuzzell, M Denise MD; Fuzzell, Sarada L SL; Hochstetler, Sherri D SD; Miskimen, Kristy K; Main, Leighanne R LR; Dorfsman, Daniel A DA; Ogrocki, Paula P; Lerner, Alan J AJ; Ramos, Jairo J; Vance, Jeffery M JM; Cuccaro, Michael L ML; Scott, William K WK; Pericak-Vance, Margaret A MA; Haines, Jonathan L JL
Effects of Alzheimer's genetic risk scores and CSF biomarkers in de novo Parkinson's Disease.
Npj Parkinson'S Disease
Lee, Young-Gun YG; Jeong, Seong Ho SH; Park, Mincheol M; Kang, Sung Woo SW; Baik, Kyoungwon K; Jeon, Seun S; Lee, Phil Hyu PH; Sohn, Young Ho YH; Ye, Byoung Seok BS
Frontal lobe microglia, neurodegenerative protein accumulation, and cognitive function in people with HIV.
Acta Neuropathologica Communications
Murray, Jacinta J; Meloni, Gregory G; Cortes, Etty P EP; KimSilva, Ariadna A; Jacobs, Michelle M; Ramkissoon, Alyssa A; Crary, John F JF; Morgello, Susan S
Signature of Alzheimer's Disease in Intestinal Microbiome: Results From the AlzBiom Study.
Frontiers In Neuroscience
Laske, Christoph C; Müller, Stephan S; Preische, Oliver O; Ruschil, Victoria V; Munk, Matthias H J MHJ; Honold, Iris I; Peter, Silke S; Schoppmeier, Ulrich U; Willmann, Matthias M
Potential protective effect against SARS-CoV-2 infection by APOE rs7412 polymorphism.
Scientific Reports
Espinosa-Salinas, Isabel I; Colmenarejo, Gonzalo G; Fernández-Díaz, Cristina M CM; Gómez de Cedrón, Marta M; Martinez, J Alfredo JA; Reglero, Guillermo G; Ramírez de Molina, Ana A
Association of Traumatic Brain Injury With and Without Loss of Consciousness With Neuropathologic Outcomes in Community-Dwelling Older Persons.
Jama Network Open
Agrawal, Sonal S; Leurgans, Sue E SE; James, Bryan D BD; Barnes, Lisa L LL; Mehta, Rupal I RI; Dams-O'Connor, Kristen K; Mez, Jesse J; Bennett, David A DA; Schneider, Julie A JA
APOE4 exacerbates α-synuclein seeding activity and contributes to neurotoxicity in Alzheimer's disease with Lewy body pathology.
Acta Neuropathologica
Jin, Yunjung Y; Li, Fuyao F; Sonoustoun, Berkiye B; Kondru, Naveen Chandra NC; Martens, Yuka A YA; Qiao, Wenhui W; Heckman, Michael G MG; Ikezu, Tadafumi C TC; Li, Zonghua Z; Burgess, Jeremy D JD; Amerna, Danilyn D; O'Leary, Justin J; DeTure, Michael A MA; Zhao, Jing J; McLean, Pamela J PJ; Dickson, Dennis W DW; Ross, Owen A OA; Bu, Guojun G; Zhao, Na N
Cortical Thickness Changes After Computerized Working Memory Training in Patients With Mild Cognitive Impairment.
Frontiers In Aging Neuroscience
Hol, Haakon R HR; Flak, Marianne M MM; Chang, Linda L; Løhaugen, Gro Christine Christensen GCC; Bjuland, Knut Jørgen KJ; Rimol, Lars M LM; Engvig, Andreas A; Skranes, Jon J; Ernst, Thomas T; Madsen, Bengt-Ove BO; Hernes, Susanne S SS
Association between peroxisome proliferator-activated receptor-alpha, -delta and -gamma gene (PPARA, PPARD, PPARG) polymorphisms and overweight parameters in physically active men.
Biology Of Sport
Maculewicz, Ewelina E; Mastalerz, Andrzej A; Maciejewska-Skrendo, Agnieszka A; Cięszczyk, Paweł P; Cywińska, Anna A; Borecka, Anna A; Garbacz, Aleksandra A; Szarska, Ewa E; Dziuda, Łukasz Ł; Lorenz, Katarzyna K; Łakomy, Roman R; Lepionka, Tomasz T; Anyżewska, Anna A; Białek, Agnieszka A; Bertrandt, Jerzy J
Manifestations of Alzheimer's disease genetic risk in the blood are evident in a multiomic analysis in healthy adults aged 18 to 90.
Scientific Reports
Heath, Laura L; Earls, John C JC; Magis, Andrew T AT; Kornilov, Sergey A SA; Lovejoy, Jennifer C JC; Funk, Cory C CC; Rappaport, Noa N; Logsdon, Benjamin A BA; Mangravite, Lara M LM; Kunkle, Brian W BW; Martin, Eden R ER; Naj, Adam C AC; Ertekin-Taner, Nilüfer N; Golde, Todd E TE; Hood, Leroy L; Price, Nathan D ND; ,
No association between APOE genotype and lipid lowering with cognitive function in a randomized controlled trial of evolocumab.
Plos One
Korthauer, Laura E LE; Giugliano, Robert P RP; Guo, Jianping J; Sabatine, Marc S MS; Sever, Peter P; Keech, Anthony A; Atar, Dan D; Kurtz, Christopher C; Ruff, Christian T CT; Mach, Francois F; Ott, Brian R BR
Meta-analysis of genome-wide association studies identifies ancestry-specific associations underlying circulating total tau levels.
Communications Biology
Sarnowski, Chloé C; Ghanbari, Mohsen M; Bis, Joshua C JC; Logue, Mark M; Fornage, Myriam M; Mishra, Aniket A; Ahmad, Shahzad S; Beiser, Alexa S AS; Boerwinkle, Eric E; Bouteloup, Vincent V; Chouraki, Vincent V; Cupples, L Adrienne LA; Damotte, Vincent V; DeCarli, Charles S CS; DeStefano, Anita L AL; Djoussé, Luc L; Fohner, Alison E AE; Franz, Carol E CE; Kautz, Tiffany F TF; Lambert, Jean-Charles JC; Lyons, Michael J MJ; Mosley, Thomas H TH; Mukamal, Kenneth J KJ; Pase, Matthew P MP; Portilla Fernandez, Eliana C EC; Rissman, Robert A RA; Satizabal, Claudia L CL; Vasan, Ramachandran S RS; Yaqub, Amber A; Debette, Stephanie S; Dufouil, Carole C; Launer, Lenore J LJ; Kremen, William S WS; Longstreth, William T WT; Ikram, M Arfan MA; Seshadri, Sudha S
Best practices for the interpretation and reporting of clinical whole genome sequencing.
Npj Genomic Medicine
Austin-Tse, Christina A CA; Jobanputra, Vaidehi V; Perry, Denise L DL; Bick, David D; Taft, Ryan J RJ; Venner, Eric E; Gibbs, Richard A RA; Young, Ted T; Barnett, Sarah S; Belmont, John W JW; Boczek, Nicole N; Chowdhury, Shimul S; Ellsworth, Katarzyna A KA; Guha, Saurav S; Kulkarni, Shashikant S; Marcou, Cherisse C; Meng, Linyan L; Murdock, David R DR; Rehman, Atteeq U AU; Spiteri, Elizabeth E; Thomas-Wilson, Amanda A; Kearney, Hutton M HM; Rehm, Heidi L HL; ,
Publication Date: 2022-04-08
Variant appearance in text: APOE: 388T>C; Cys130Arg
Personalized Dietary Recommendations Based on Lipid-Related Genetic Variants: A Systematic Review.
Frontiers In Nutrition
Pérez-Beltrán, Yolanda E YE; Rivera-Iñiguez, Ingrid I; Gonzalez-Becerra, Karina K; Pérez-Naitoh, Naomi N; Tovar, Juscelino J; Sáyago-Ayerdi, Sonia G SG; Mendivil, Edgar J EJ
Genome-Wide Association Study of Alzheimer's Disease Brain Imaging Biomarkers and Neuropsychological Phenotypes in the European Medical Information Framework for Alzheimer's Disease Multimodal Biomarker Discovery Dataset.
Frontiers In Aging Neuroscience
Homann, Jan J; Osburg, Tim T; Ohlei, Olena O; Dobricic, Valerija V; Deecke, Laura L; Bos, Isabelle I; Vandenberghe, Rik R; Gabel, Silvy S; Scheltens, Philip P; Teunissen, Charlotte E CE; Engelborghs, Sebastiaan S; Frisoni, Giovanni G; Blin, Olivier O; Richardson, Jill C JC; Bordet, Regis R; Lleó, Alberto A; Alcolea, Daniel D; Popp, Julius J; Clark, Christopher C; Peyratout, Gwendoline G; Martinez-Lage, Pablo P; Tainta, Mikel M; Dobson, Richard J B RJB; Legido-Quigley, Cristina C; Sleegers, Kristel K; Van Broeckhoven, Christine C; Wittig, Michael M; Franke, Andre A; Lill, Christina M CM; Blennow, Kaj K; Zetterberg, Henrik H; Lovestone, Simon S; Streffer, Johannes J; Ten Kate, Mara M; Vos, Stephanie J B SJB; Barkhof, Frederik F; Visser, Pieter Jelle PJ; Bertram, Lars L
Association of Genetic Variants Linked to Late-Onset Alzheimer Disease With Cognitive Test Performance by Midlife.
Jama Network Open
Zimmerman, Scott C SC; Brenowitz, Willa D WD; Calmasini, Camilla C; Ackley, Sarah F SF; Graff, Rebecca E RE; Asiimwe, Stephen B SB; Staffaroni, Adam M AM; Hoffmann, Thomas J TJ; Glymour, M Maria MM
CAG Repeats Within the Non-pathological Range in the HTT Gene Influence Personality Traits in Patients With Subjective Cognitive Decline: A 13-Year Follow-Up Study.
Patterns of amygdala region pathology in LATE-NC: subtypes that differ with regard to TDP-43 histopathology, genetic risk factors, and comorbid pathologies.
Acta Neuropathologica
Cykowski, Matthew D MD; Arumanayagam, Anithachristy S AS; Powell, Suzanne Z SZ; Rivera, Andreana L AL; Abner, Erin L EL; Roman, Gustavo C GC; Masdeu, Joseph C JC; Nelson, Peter T PT
Empowering consumers to PREVENT diet-related diseases through OMICS sciences (PREVENTOMICS): protocol for a parallel double-blinded randomised intervention trial to investigate biomarker-based nutrition plans for weight loss.
Bmj Open
Aldubayan, Mona Adnan MA; Pigsborg, Kristina K; Gormsen, Sophia M O SMO; Serra, Francisca F; Palou, Mariona M; Mena, Pedro P; Wetzels, Mart M; Calleja, Alberto A; Caimari, Antoni A; Del Bas, Josep J; Gutierrez, Biotza B; Magkos, Faidon F; Hjorth, Mads Fiil MF
Combined homocysteine and apoE rs429358 and rs7412 polymorphism in association with serum lipid levels and cognition in Chinese community-dwelling older adults.
Bmc Psychiatry
Wang, Chunxiu C; Ji, Xunming X; Tang, Zhe Z; Zhang, Zhongying Z; Gu, Xiang X; Fang, Xianghua X
VEGF-A-related genetic variants protect against Alzheimer's disease.
Aging
Petrelis, Alexandros M AM; Stathopoulou, Maria G MG; Kafyra, Maria M; Murray, Helena H; Masson, Christine C; Lamont, John J; Fitzgerald, Peter P; Dedoussis, George G; Yen, Frances T FT; Visvikis-Siest, Sophie S
Cerebrospinal fluid tau levels are associated with abnormal neuronal plasticity markers in Alzheimer's disease.
Molecular Neurodegeneration
Visser, Pieter Jelle PJ; Reus, Lianne M LM; Gobom, Johan J; Jansen, Iris I; Dicks, Ellen E; van der Lee, Sven J SJ; Tsolaki, Magda M; Verhey, Frans R J FRJ; Popp, Julius J; Martinez-Lage, Pablo P; Vandenberghe, Rik R; Lleó, Alberto A; Molinuevo, José Luís JL; Engelborghs, Sebastiaan S; Freund-Levi, Yvonne Y; Froelich, Lutz L; Sleegers, Kristel K; Dobricic, Valerija V; Lovestone, Simon S; Streffer, Johannes J; Vos, Stephanie J B SJB; Bos, Isabelle I; , ; Smit, August B AB; Blennow, Kaj K; Scheltens, Philip P; Teunissen, Charlotte E CE; Bertram, Lars L; Zetterberg, Henrik H; Tijms, Betty M BM
Proteomic differences in hippocampus and cortex of sudden unexplained death in childhood.
Acta Neuropathologica
Leitner, Dominique F DF; William, Christopher C; Faustin, Arline A; Askenazi, Manor M; Kanshin, Evgeny E; Snuderl, Matija M; McGuone, Declan D; Wisniewski, Thomas T; Ueberheide, Beatrix B; Gould, Laura L; Devinsky, Orrin O
Effects of Apolipoprotein E polymorphism on carotid intima-media thickness, incident myocardial infarction and incident stroke.
Scientific Reports
Pitchika, Anitha A; Markus, Marcello Ricardo Paulista MRP; Schipf, Sabine S; Teumer, Alexander A; Van der Auwera, Sandra S; Nauck, Matthias M; Dörr, Marcus M; Felix, Stephan S; Grabe, Hans-Jörgen HJ; Völzke, Henry H; Ittermann, Till T
Twelve Variants Polygenic Score for Low-Density Lipoprotein Cholesterol Distribution in a Large Cohort of Patients With Clinically Diagnosed Familial Hypercholesterolemia With or Without Causative Mutations.
Journal Of The American Heart Association
Olmastroni, Elena E; Gazzotti, Marta M; Arca, Marcello M; Averna, Maurizio M; Pirillo, Angela A; Catapano, Alberico Luigi AL; Casula, Manuela M; ,
Are apolipoprotein E fragments a promising new therapeutic target for Alzheimer's disease?
Therapeutic Advances In Chronic Disease
Vecchio, Filomena Lo FL; Bisceglia, Paola P; Imbimbo, Bruno Pietro BP; Lozupone, Madia M; Latino, Raffaela Rita RR; Resta, Emanuela E; Leone, Maurizio M; Solfrizzi, Vincenzo V; Greco, Antonio A; Daniele, Antonio A; Watling, Mark M; Panza, Francesco F; Seripa, Davide D
Bacillus Calmette-Guérin Treatment Changes the Tumor Microenvironment of Non-Muscle-Invasive Bladder Cancer.
Frontiers In Oncology
Su, Fei F; Liu, Ming M; Zhang, Wei W; Tang, Min M; Zhang, Jinsong J; Li, Hexin H; Zou, Lihui L; Zhang, Rui R; Liu, Yudong Y; Li, Lin L; Ma, Jie J; Zhang, Yaqun Y; Chen, Meng M; Xiao, Fei F
VALZ-Pilot: High-dose valacyclovir treatment in patients with early-stage Alzheimer's disease.
Alzheimer'S & Dementia (New York, N. Y.)
Weidung, Bodil B; Hemmingsson, Eva-Stina ES; Olsson, Jan J; Sundström, Torbjörn T; Blennow, Kaj K; Zetterberg, Henrik H; Ingelsson, Martin M; Elgh, Fredrik F; Lövheim, Hugo H
A genome-wide association study of outcome from traumatic brain injury.
Ebiomedicine
Kals, Mart M; Kunzmann, Kevin K; Parodi, Livia L; Radmanesh, Farid F; Wilson, Lindsay L; Izzy, Saef S; Anderson, Christopher D CD; Puccio, Ava M AM; Okonkwo, David O DO; Temkin, Nancy N; Steyerberg, Ewout W EW; Stein, Murray B MB; Manley, Geoff T GT; Maas, Andrew I R AIR; Richardson, Sylvia S; Diaz-Arrastia, Ramon R; Palotie, Aarno A; Ripatti, Samuli S; Rosand, Jonathan J; Menon, David K DK; ,
Association of a wide range of chronic diseases and apolipoprotein E4 genotype with subsequent risk of dementia in community-dwelling adults: A retrospective cohort study.
Clinical, Neurophysiological, and Genetic Predictors of Recovery in Patients With Severe Acquired Brain Injuries (PRABI): A Study Protocol for a Longitudinal Observational Study.
Frontiers In Neurology
Hakiki, Bahia B; Donnini, Ida I; Romoli, Anna Maria AM; Draghi, Francesca F; Maccanti, Daniela D; Grippo, Antonello A; Scarpino, Maenia M; Maiorelli, Antonio A; Sterpu, Raisa R; Atzori, Tiziana T; Mannini, Andrea A; Campagnini, Silvia S; Bagnoli, Silvia S; Ingannato, Assunta A; Nacmias, Benedetta B; De Bellis, Francesco F; Estraneo, Anna A; Carli, Valentina V; Pasqualone, Eugenia E; Comanducci, Angela A; Navarro, Jorghe J; Carrozza, Maria Chiara MC; Macchi, Claudio C; Cecchi, Francesca F
Plasma and CSF NfL are differentially associated with biomarker evidence of neurodegeneration in a community-based sample of 70-year-olds.
Alzheimer'S & Dementia (Amsterdam, Netherlands)
Dittrich, Anna A; Ashton, Nicholas J NJ; Zetterberg, Henrik H; Blennow, Kaj K; Simrén, Joel J; Geiger, Fiona F; Zettergren, Anna A; Shams, Sara S; Machado, Alejandra A; Westman, Eric E; Schöll, Michael M; Skoog, Ingmar I; Kern, Silke S
Integrative genetic and immune cell analysis of plasma proteins in healthy donors identifies novel associations involving primary immune deficiency genes.
Genome Medicine
Caron, Barthelemy B; Patin, Etienne E; Rotival, Maxime M; Charbit, Bruno B; Albert, Matthew L ML; Quintana-Murci, Lluis L; Duffy, Darragh D; Rausell, Antonio A; ,
Association of SPI1 Haplotypes with Altered SPI1 Gene Expression and Alzheimer's Disease Risk.
Journal Of Alzheimer'S Disease : Jad
Cao, Han H; Zhou, Xiaopu X; Chen, Yu Y; Ip, Fanny C F FCF; Chen, Yuewen Y; Lai, Nicole C H NCH; Lo, Ronnie M N RMN; Tong, Estella P S EPS; Mok, Vincent C T VCT; Kwok, Timothy C Y TCY; , ; Fu, Amy K Y AKY; Ip, Nancy Y NY