Publications:

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Alzheimer's Disease: Treatment Strategies and Their Limitations.

International Journal Of Molecular Sciences

Passeri, Elodie E; Elkhoury, Kamil K; Morsink, Margaretha M; Broersen, Kerensa K; Linder, Michel M; Tamayol, Ali A; Malaplate, Catherine C; Yen, Frances T FT; Arab-Tehrany, Elmira E

Publication Date: 2022-11-12

Variant appearance in text: APOE: L166P

PubMed Link: 36430432

Variant Present in the following documents:

• ijms-23-13954.pdf

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Medin co-aggregates with vascular amyloid-β in Alzheimer's disease.

Nature

Wagner, Jessica J; Degenhardt, Karoline K; Veit, Marleen M; Louros, Nikolaos N; Konstantoulea, Katerina K; Skodras, Angelos A; Wild, Katleen K; Liu, Ping P; Obermüller, Ulrike U; Bansal, Vikas V; Dalmia, Anupriya A; Häsler, Lisa M LM; Lambert, Marius M; De Vleeschouwer, Matthias M; Davies, Hannah A HA; Madine, Jillian J; Kronenberg-Versteeg, Deborah D; Feederle, Regina R; Del Turco, Domenico D; Nilsson, K Peter R KPR; Lashley, Tammaryn T; Deller, Thomas T; Gearing, Marla M; Walker, Lary C LC; Heutink, Peter P; Rousseau, Frederic F; Schymkowitz, Joost J; Jucker, Mathias M; Neher, Jonas J JJ

Publication Date: 2022-12

Variant appearance in text: APOE: L166P

PubMed Link: 36385530

Variant Present in the following documents:

• Main text

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Mitigating Effect of Estrogen in Alzheimer's Disease-Mimicking Cerebral Organoid.

Frontiers In Neuroscience

Kim, Jennifer Yejean JY; Mo, Hyunkyung H; Kim, Juryun J; Kim, Jang Woon JW; Nam, Yoojun Y; Rim, Yeri Alice YA; Ju, Ji Hyeon JH

Publication Date: 2022

Variant appearance in text: APOE: L166P

PubMed Link: 35401074

Variant Present in the following documents:

• fnins-16-816174.pdf

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Apolipoprotein E and Alzheimer's disease.

Acta Pharmaceutica Sinica. B

Troutwine, Benjamin R BR; Hamid, Laylan L; Lysaker, Colton R CR; Strope, Taylor A TA; Wilkins, Heather M HM

Publication Date: 2022-02

Variant appearance in text: APOE: L166P

PubMed Link: 35256931

Variant Present in the following documents:

• Main text

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APOE and Alzheimer's disease: advances in genetics, pathophysiology, and therapeutic approaches.

The Lancet. Neurology

Serrano-Pozo, Alberto A; Das, Sudeshna S; Hyman, Bradley T BT

Publication Date: 2021-01

Variant appearance in text: APOE: L166P

PubMed Link: 33340485

Variant Present in the following documents:

• Main text
• nihms-1684246.pdf

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Therapeutic Targeting Strategies for Early- to Late-Staged Alzheimer's Disease.

International Journal Of Molecular Sciences

Kang, You Jung YJ; Diep, Yen N YN; Tran, Minh M; Cho, Hansang H

Publication Date: 2020-12-16

Variant appearance in text: APOE: L166P

PubMed Link: 33339351

Variant Present in the following documents:

• Main text

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Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology

Rayaprolu, Sruti S; Higginbotham, Lenora L; Bagchi, Pritha P; Watson, Caroline M CM; Zhang, Tian T; Levey, Allan I AI; Rangaraju, Srikant S; Seyfried, Nicholas T NT

Publication Date: 2021-01

Variant appearance in text: APOE: L166P

PubMed Link: 32898852

Variant Present in the following documents:

• 41386_2020_Article_840.pdf

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25-Hydroxycholesterol amplifies microglial IL-1β production in an apoE isoform-dependent manner.

Journal Of Neuroinflammation

Wong, Man Ying MY; Lewis, Michael M; Doherty, James J JJ; Shi, Yang Y; Cashikar, Anil G AG; Amelianchik, Anna A; Tymchuk, Svitlana S; Sullivan, Patrick M PM; Qian, Mingxing M; Covey, Douglas F DF; Petsko, Gregory A GA; Holtzman, David M DM; Paul, Steven M SM; Luo, Wenjie W

Publication Date: 2020-06-17

Variant appearance in text: APOE: L166P

PubMed Link: 32552741

Variant Present in the following documents:

• Main text
• 12974_2020_Article_1869.pdf

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Regulation of amyloid-β dynamics and pathology by the circadian clock.

The Journal Of Experimental Medicine

Kress, Geraldine J GJ; Liao, Fan F; Dimitry, Julie J; Cedeno, Michelle R MR; FitzGerald, Garret A GA; Holtzman, David M DM; Musiek, Erik S ES

Publication Date: 2018-04-02

Variant appearance in text: APOE: L166P

PubMed Link: 29382695

Variant Present in the following documents:

• Main text

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Apolipoprotein E4 Elicits Lysosomal Cathepsin D Release, Decreased Thioredoxin-1 Levels, and Apoptosis.

Journal Of Alzheimer'S Disease : Jad

Persson, Torbjörn T; Lattanzio, Francesca F; Calvo-Garrido, Javier J; Rimondini, Roberto R; Rubio-Rodrigo, Marta M; Sundström, Erik E; Maioli, Silvia S; Sandebring-Matton, Anna A; Cedazo-Mínguez, Ángel Á

Publication Date: 2017

Variant appearance in text: APOE: L166P

PubMed Link: 28035917

Variant Present in the following documents:

• jad-56-jad150738.pdf

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Revisiting rodent models: Octodon degus as Alzheimer's disease model?

Acta Neuropathologica Communications

Steffen, Johannes J; Krohn, Markus M; Paarmann, Kristin K; Schwitlick, Christina C; Brüning, Thomas T; Marreiros, Rita R; Müller-Schiffmann, Andreas A; Korth, Carsten C; Braun, Katharina K; Pahnke, Jens J

Publication Date: 2016-08-26

Variant appearance in text: APOE: L166P

PubMed Link: 27566602

Variant Present in the following documents:

• Main text
• 40478_2016_Article_363.pdf

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APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective.

Journal Of Neurochemistry

Tai, Leon M LM; Ghura, Shivesh S; Koster, Kevin P KP; Liakaite, Vaiva V; Maienschein-Cline, Mark M; Kanabar, Pinal P; Collins, Nicole N; Ben-Aissa, Manel M; Lei, Arden Zhengdeng AZ; Bahroos, Neil N; Green, Stefan J SJ; Hendrickson, Bill B; Van Eldik, Linda J LJ; LaDu, Mary Jo MJ

Publication Date: 2015-05

Variant appearance in text: APOE: L166P

PubMed Link: 25689586

Variant Present in the following documents:

• JNC-133-465.pdf

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Evidence of a novel mechanism for partial γ-secretase inhibition induced paradoxical increase in secreted amyloid β protein.

Plos One

Barnwell, Eliza E; Padmaraju, Vasudevaraju V; Baranello, Robert R; Pacheco-Quinto, Javier J; Crosson, Craig C; Ablonczy, Zsolt Z; Eckman, Elizabeth E; Eckman, Christopher B CB; Ramakrishnan, Viswanathan V; Greig, Nigel H NH; Pappolla, Miguel A MA; Sambamurti, Kumar K

Publication Date: 2014

Variant appearance in text: APOE: L166P

PubMed Link: 24658363

Variant Present in the following documents:

• pone.0091531.pdf

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