Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice.
Frontiers In Aging Neuroscience
den Hoedt, Sandra S; Crivelli, Simone M SM; Leijten, Frank P J FPJ; Losen, Mario M; Stevens, Jo A A JAA; Mané-Damas, Marina M; de Vries, Helga E HE; Walter, Jochen J; Mirzaian, Mina M; Sijbrands, Eric J G EJG; Aerts, Johannes M F G JMFG; Verhoeven, Adrie J M AJM; Martinez-Martinez, Pilar P; Mulder, Monique T MT
Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.
Nature Communications
McQuade, Amanda A; Kang, You Jung YJ; Hasselmann, Jonathan J; Jairaman, Amit A; Sotelo, Alexandra A; Coburn, Morgan M; Shabestari, Sepideh Kiani SK; Chadarevian, Jean Paul JP; Fote, Gianna G; Tu, Christina H CH; Danhash, Emma E; Silva, Jorge J; Martinez, Eric E; Cotman, Carl C; Prieto, G Aleph GA; Thompson, Leslie M LM; Steffan, Joan S JS; Smith, Ian I; Davtyan, Hayk H; Cahalan, Michael M; Cho, Hansang H; Blurton-Jones, Mathew M
Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau.
Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Rayaprolu, Sruti S; Higginbotham, Lenora L; Bagchi, Pritha P; Watson, Caroline M CM; Zhang, Tian T; Levey, Allan I AI; Rangaraju, Srikant S; Seyfried, Nicholas T NT
APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective.
Journal Of Neurochemistry
Tai, Leon M LM; Ghura, Shivesh S; Koster, Kevin P KP; Liakaite, Vaiva V; Maienschein-Cline, Mark M; Kanabar, Pinal P; Collins, Nicole N; Ben-Aissa, Manel M; Lei, Arden Zhengdeng AZ; Bahroos, Neil N; Green, Stefan J SJ; Hendrickson, Bill B; Van Eldik, Linda J LJ; LaDu, Mary Jo MJ
Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.
The Journal Of Biological Chemistry
Tai, Leon M LM; Bilousova, Tina T; Jungbauer, Lisa L; Roeske, Stephen K SK; Youmans, Katherine L KL; Yu, Chunjiang C; Poon, Wayne W WW; Cornwell, Lindsey B LB; Miller, Carol A CA; Vinters, Harry V HV; Van Eldik, Linda J LJ; Fardo, David W DW; Estus, Steve S; Bu, Guojun G; Gylys, Karen Hoppens KH; Ladu, Mary Jo MJ