APOE c.856C>G ;(p.L286V)

Variant ID: 19-45412409-C-G

NM_000041.2(APOE):c.856C>G;(p.L286V)

This variant was identified in 16 publications

View GRCh38 version.




Publications:


Proteomic Exploration of Paraoxonase 1 Function in Health and Disease.

International Journal Of Molecular Sciences
Jakubowski, Hieronim H
Publication Date: 2023-04-24

Variant appearance in text: APOE: L286V
PubMed Link: 37175471
Variant Present in the following documents:
  • Main text
  • ijms-24-07764.pdf
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Temporal and Sex-Linked Protein Expression Dynamics in a Familial Model of Alzheimer's Disease.

Molecular & Cellular Proteomics : Mcp
Blasco Tavares Pereira Lopes, Filipa F; Schlatzer, Daniela D; Wang, Rihua R; Li, Xiaolin X; Feng, Emily E; Koyutürk, Mehmet M; Qi, Xin X; Chance, Mark R MR
Publication Date: 2022-09

Variant appearance in text: APOE: L286V
PubMed Link: 35944844
Variant Present in the following documents:
  • Main text
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Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence.

Communications Biology
Pan, Jin-Xiu JX; Sun, Dong D; Lee, Daehoon D; Xiong, Lei L; Ren, Xiao X; Guo, Hao-Han HH; Yao, Ling-Ling LL; Lu, Yuyi Y; Jung, Caroline C; Xiong, Wen-Cheng WC
Publication Date: 2021-11-25

Variant appearance in text: APOE: L286V
PubMed Link: 34824365
Variant Present in the following documents:
  • Main text
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Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence.

Communications Biology
Pan, Jin-Xiu JX; Sun, Dong D; Lee, Daehoon D; Xiong, Lei L; Ren, Xiao X; Guo, Hao-Han HH; Yao, Ling-Ling LL; Lu, Yuyi Y; Jung, Caroline C; Xiong, Wen-Cheng WC
Publication Date: 2021-11-25

Variant appearance in text: APOE: L286V
PubMed Link: 34824365
Variant Present in the following documents:
  • Main text
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Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice.

Frontiers In Aging Neuroscience
den Hoedt, Sandra S; Crivelli, Simone M SM; Leijten, Frank P J FPJ; Losen, Mario M; Stevens, Jo A A JAA; Mané-Damas, Marina M; de Vries, Helga E HE; Walter, Jochen J; Mirzaian, Mina M; Sijbrands, Eric J G EJG; Aerts, Johannes M F G JMFG; Verhoeven, Adrie J M AJM; Martinez-Martinez, Pilar P; Mulder, Monique T MT
Publication Date: 2021

Variant appearance in text: APOE: L286V
PubMed Link: 34776936
Variant Present in the following documents:
  • Main text
  • fnagi-13-765252.pdf
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Accelerated long-term forgetting is a BACE1 inhibitor-reversible incipient cognitive phenotype in Alzheimer's disease model mice.

Neuropsychopharmacology Reports
Ohno, Masuo M
Publication Date: 2021-06

Variant appearance in text: APOE: L286V
PubMed Link: 33749160
Variant Present in the following documents:
  • NPR2-41-255.pdf
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Adult Hippocampal Neurogenesis in Aging and Alzheimer's Disease.

Stem Cell Reports
Babcock, Kelsey R KR; Page, John S JS; Fallon, Justin R JR; Webb, Ashley E AE
Publication Date: 2021-04-13

Variant appearance in text: APOE: L286V
PubMed Link: 33636114
Variant Present in the following documents:
  • Main text
  • main.pdf
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Causes and consequences of baseline cerebral blood flow reductions in Alzheimer's disease.

Journal Of Cerebral Blood Flow And Metabolism : Official Journal Of The International Society Of Cerebral Blood Flow And Metabolism
Bracko, Oliver O; Cruz Hernández, Jean C JC; Park, Laibaik L; Nishimura, Nozomi N; Schaffer, Chris B CB
Publication Date: 2021-07

Variant appearance in text: APOE: L286V
PubMed Link: 33444096
Variant Present in the following documents:
  • Main text
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Gene expression and functional deficits underlie TREM2-knockout microglia responses in human models of Alzheimer's disease.

Nature Communications
McQuade, Amanda A; Kang, You Jung YJ; Hasselmann, Jonathan J; Jairaman, Amit A; Sotelo, Alexandra A; Coburn, Morgan M; Shabestari, Sepideh Kiani SK; Chadarevian, Jean Paul JP; Fote, Gianna G; Tu, Christina H CH; Danhash, Emma E; Silva, Jorge J; Martinez, Eric E; Cotman, Carl C; Prieto, G Aleph GA; Thompson, Leslie M LM; Steffan, Joan S JS; Smith, Ian I; Davtyan, Hayk H; Cahalan, Michael M; Cho, Hansang H; Blurton-Jones, Mathew M
Publication Date: 2020-10-23

Variant appearance in text: APOE: L286V
PubMed Link: 33097708
Variant Present in the following documents:
  • 41467_2020_Article_19227.pdf
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Systems-based proteomics to resolve the biology of Alzheimer's disease beyond amyloid and tau.

Neuropsychopharmacology : Official Publication Of The American College Of Neuropsychopharmacology
Rayaprolu, Sruti S; Higginbotham, Lenora L; Bagchi, Pritha P; Watson, Caroline M CM; Zhang, Tian T; Levey, Allan I AI; Rangaraju, Srikant S; Seyfried, Nicholas T NT
Publication Date: 2021-01

Variant appearance in text: APOE: L286V
PubMed Link: 32898852
Variant Present in the following documents:
  • 41386_2020_Article_840.pdf
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Reduced Acoustic Startle Response and Prepulse Inhibition in the Tg4-42 Model of Alzheimer's Disease.

Journal Of Alzheimer'S Disease Reports
Sichler, Marius E ME; Löw, Maximilian J MJ; Schleicher, Eva M EM; Bayer, Thomas A TA; Bouter, Yvonne Y
Publication Date: 2019-11-21

Variant appearance in text: APOE: L286V
PubMed Link: 31867566
Variant Present in the following documents:
  • Main text
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Sevoflurane increases locomotion activity in mice.

Plos One
Ton, Hoai T HT; Yang, Lei L; Xie, Zhongcong Z
Publication Date: 2019

Variant appearance in text: APOE: L286V
PubMed Link: 31112538
Variant Present in the following documents:
  • pone.0206649.pdf
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Intrahippocampal injection of a lentiviral vector expressing neurogranin enhances cognitive function in 5XFAD mice.

Experimental & Molecular Medicine
Jeon, Seong Gak SG; Kang, Moonkyung M; Kim, Yeon-Soo YS; Kim, Dong-Hyun DH; Nam, Dong Woo DW; Song, Eun Ji EJ; Mook-Jung, Inhee I; Moon, Minho M
Publication Date: 2018-03-23

Variant appearance in text: APOE: L286V
PubMed Link: 29568074
Variant Present in the following documents:
  • emm2017302a.pdf
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Sortilin-Related Receptor Expression in Human Neural Stem Cells Derived from Alzheimer's Disease Patients Carrying the APOE Epsilon 4 Allele.

Neural Plasticity
Zollo, Alen A; Allen, Zoe Z; Rasmussen, Helle F HF; Iannuzzi, Filomena F; Shi, Yichen Y; Larsen, Agnete A; Maier, Thorsten J TJ; Matrone, Carmela C
Publication Date: 2017

Variant appearance in text: APOE: L286V
PubMed Link: 28634550
Variant Present in the following documents:
  • Main text
  • NP2017-1892612.pdf
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Lipid microdomain modification sustains neuronal viability in models of Alzheimer's disease.

Acta Neuropathologica Communications
Herzer, Silke S; Meldner, Sascha S; Rehder, Klara K; Gröne, Hermann-Josef HJ; Nordström, Viola V
Publication Date: 2016-09-17

Variant appearance in text: APOE: L286V
PubMed Link: 27639375
Variant Present in the following documents:
  • 40478_2016_Article_354.pdf
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APOE-modulated Aβ-induced neuroinflammation in Alzheimer's disease: current landscape, novel data, and future perspective.

Journal Of Neurochemistry
Tai, Leon M LM; Ghura, Shivesh S; Koster, Kevin P KP; Liakaite, Vaiva V; Maienschein-Cline, Mark M; Kanabar, Pinal P; Collins, Nicole N; Ben-Aissa, Manel M; Lei, Arden Zhengdeng AZ; Bahroos, Neil N; Green, Stefan J SJ; Hendrickson, Bill B; Van Eldik, Linda J LJ; LaDu, Mary Jo MJ
Publication Date: 2015-05

Variant appearance in text: APOE: L286V
PubMed Link: 25689586
Variant Present in the following documents:
  • JNC-133-465.pdf
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Levels of soluble apolipoprotein E/amyloid-β (Aβ) complex are reduced and oligomeric Aβ increased with APOE4 and Alzheimer disease in a transgenic mouse model and human samples.

The Journal Of Biological Chemistry
Tai, Leon M LM; Bilousova, Tina T; Jungbauer, Lisa L; Roeske, Stephen K SK; Youmans, Katherine L KL; Yu, Chunjiang C; Poon, Wayne W WW; Cornwell, Lindsey B LB; Miller, Carol A CA; Vinters, Harry V HV; Van Eldik, Linda J LJ; Fardo, David W DW; Estus, Steve S; Bu, Guojun G; Gylys, Karen Hoppens KH; Ladu, Mary Jo MJ
Publication Date: 2013-02-22

Variant appearance in text: APOE: L286V
PubMed Link: 23293020
Variant Present in the following documents:
  • Main text
View BVdb publication page