MED16 c.1347C>G ;(p.H449Q)

Variant ID: 19-879943-G-C

NM_005481.2(MED16):c.1347C>G;(p.H449Q)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.

Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Publication Date: 2023-04-03

Variant appearance in text: MED16: H449Q
PubMed Link: 37012232
Variant Present in the following documents:
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 3
  • 41467_2023_37547_MOESM12_ESM.xlsx, sheet 2
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 4
  • 41467_2023_37547_MOESM10_ESM.xlsx, sheet 2
View BVdb publication page



Patient-derived models recapitulate heterogeneity of molecular signatures and drug response in pediatric high-grade glioma.

Nature Communications
He, Chen C; Xu, Ke K; Zhu, Xiaoyan X; Dunphy, Paige S PS; Gudenas, Brian B; Lin, Wenwei W; Twarog, Nathaniel N; Hover, Laura D LD; Kwon, Chang-Hyuk CH; Kasper, Lawryn H LH; Zhang, Junyuan J; Li, Xiaoyu X; Dalton, James J; Jonchere, Barbara B; Mercer, Kimberly S KS; Currier, Duane G DG; Caufield, William W; Wang, Yingzhe Y; Xie, Jia J; Broniscer, Alberto A; Wetmore, Cynthia C; Upadhyaya, Santhosh A SA; Qaddoumi, Ibrahim I; Klimo, Paul P; Boop, Frederick F; Gajjar, Amar A; Zhang, Jinghui J; Orr, Brent A BA; Robinson, Giles W GW; Monje, Michelle M; Freeman Iii, Burgess B BB; Roussel, Martine F MF; Northcott, Paul A PA; Chen, Taosheng T; Rankovic, Zoran Z; Wu, Gang G; Chiang, Jason J; Tinkle, Christopher L CL; Shelat, Anang A AA; Baker, Suzanne J SJ
Publication Date: 2021-07-02

Variant appearance in text: MED16: H449Q
PubMed Link: 34215733
Variant Present in the following documents:
  • 41467_2021_24168_MOESM5_ESM.xlsx, sheet 7
View BVdb publication page



A large peptidome dataset improves HLA class I epitope prediction across most of the human population.

Nature Biotechnology
Sarkizova, Siranush S; Klaeger, Susan S; Le, Phuong M PM; Li, Letitia W LW; Oliveira, Giacomo G; Keshishian, Hasmik H; Hartigan, Christina R CR; Zhang, Wandi W; Braun, David A DA; Ligon, Keith L KL; Bachireddy, Pavan P; Zervantonakis, Ioannis K IK; Rosenbluth, Jennifer M JM; Ouspenskaia, Tamara T; Law, Travis T; Justesen, Sune S; Stevens, Jonathan J; Lane, William J WJ; Eisenhaure, Thomas T; Lan Zhang, Guang G; Clauser, Karl R KR; Hacohen, Nir N; Carr, Steven A SA; Wu, Catherine J CJ; Keskin, Derin B DB
Publication Date: 2020-02

Variant appearance in text: MED16: H449Q
PubMed Link: 31844290
Variant Present in the following documents:
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 32
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 41
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 67
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 52
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 70
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 95
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 21
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 90
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 55
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 71
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 57
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 68
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 94
  • NIHMS1541512-supplement-Sup_Data2.xlsx, sheet 4
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 53
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 34
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 89
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 7
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 28
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 49
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 40
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 93
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 42
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 37
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 96
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 33
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 36
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 50
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 45
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 5
  • NIHMS1541512-supplement-Sup_Data2.xlsx, sheet 3
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 64
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 91
  • NIHMS1541512-supplement-Sup_Data2.xlsx, sheet 5
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 51
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 24
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 66
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 65
  • NIHMS1541512-supplement-Sup_Data1.xlsx, sheet 12
View BVdb publication page



Whole-genome sequencing in multiplex families with psychoses reveals mutations in the SHANK2 and SMARCA1 genes segregating with illness.

Molecular Psychiatry
Homann, O R OR; Misura, K K; Lamas, E E; Sandrock, R W RW; Nelson, P P; McDonough, S I SI; DeLisi, L E LE
Publication Date: 2016-12

Variant appearance in text: MED16: H449Q; rs76403059
PubMed Link: 27001614
Variant Present in the following documents:
  • NIHMS753666-supplement-2.xlsx, sheet 5
View BVdb publication page



BRAF V600E mutation in early-stage multiple myeloma: good response to broad acting drugs and no relation to prognosis.

Blood Cancer Journal
Rustad, E H EH; Dai, H Y HY; Hov, H H; Coward, E E; Beisvag, V V; Myklebost, O O; Hovig, E E; Nakken, S S; Vodák, D D; Meza-Zepeda, L A LA; Sandvik, A K AK; Wader, K F KF; Misund, K K; Sundan, A A; Aarset, H H; Waage, A A
Publication Date: 2015-03-20

Variant appearance in text: MED16: H449Q; rs76403059
PubMed Link: 25794135
Variant Present in the following documents:
  • bcj201524x1.xls, sheet 1
View BVdb publication page