RAB27B controls palmitoylation-dependent NRAS trafficking and signaling in myeloid leukemia.
The Journal Of Clinical Investigation
Ren, Jian-Gang JG; Xing, Bowen B; Lv, Kaosheng K; O'Keefe, Rachel A RA; Wu, Mengfang M; Wang, Ruoxing R; Bauer, Kaylyn M KM; Ghazaryan, Arevik A; Burslem, George M GM; Zhang, Jing J; O'Connell, Ryan M RM; Pillai, Vinodh V; Hexner, Elizabeth O EO; Philips, Mark R MR; Tong, Wei W
Genomic profiles of IDH-mutant gliomas: MYCN-amplified IDH-mutant astrocytoma had the worst prognosis.
Scientific Reports
Lee, Kwanghoon K; Kim, Seong-Ik SI; Kim, Eric Eunshik EE; Shim, Yu-Mi YM; Won, Jae-Kyung JK; Park, Chul-Kee CK; Choi, Seung Hong SH; Yun, Hongseok H; Lee, Hyunju H; Park, Sung-Hye SH
Postoperative risk of IDH mutant glioma-associated seizures and their potential management with IDH mutant inhibitors.
The Journal Of Clinical Investigation
Drumm, Michael M; Wang, Wenxia W; Sears, Thomas K TK; Bell-Burdett, Kirsten K; Javier, Rodrigo R; Cotton, Kristen Y KY; Webb, Brynna T BT; Byrne, Kayla T KT; Unruh, Dusten D; Thirunavu, Vineeth V; Walshon, Jordain J; Steffens, Alicia A; McCortney, Kathleen K; Lukas, Rimas V RV; Phillips, Joanna J JJ; Mohamed, Esraa E; Finan, John D JD; Santana-Santos, Lucas L; Heimberger, Amy B AB; Franz, Colin K CK; Kurz, Jonathan E JE; Templer, Jessica W JW; Swanson, Geoffrey T GT; Horbinski, Craig C
Influence of MMR, MGMT Promotor Methylation and Protein Expression on Overall and Progression-Free Survival in Primary Glioblastoma Patients Treated with Temozolomide.
International Journal Of Molecular Sciences
Brawanski, Konstantin R KR; Sprung, Susanne S; Freyschlag, Christian F CF; Hoeftberger, Romana R; Ströbel, Thomas T; Haybaeck, Johannes J; Thomé, Claudius C; Manzl, Claudia C; Birkl-Toeglhofer, Anna M AM
Predicting response to enzalutamide and abiraterone in metastatic prostate cancer using whole-omics machine learning.
Nature Communications
de Jong, Anouk C AC; Danyi, Alexandra A; van Riet, Job J; de Wit, Ronald R; Sjöström, Martin M; Feng, Felix F; de Ridder, Jeroen J; Lolkema, Martijn P MP
Publication Date: 2023-04-08
Variant appearance in text: IDH1: R132H; rs121913500
Workflow enabling deepscale immunopeptidome, proteome, ubiquitylome, phosphoproteome, and acetylome analyses of sample-limited tissues.
Nature Communications
Abelin, Jennifer G JG; Bergstrom, Erik J EJ; Rivera, Keith D KD; Taylor, Hannah B HB; Klaeger, Susan S; Xu, Charles C; Verzani, Eva K EK; Jackson White, C C; Woldemichael, Hilina B HB; Virshup, Maya M; Olive, Meagan E ME; Maynard, Myranda M; Vartany, Stephanie A SA; Allen, Joseph D JD; Phulphagar, Kshiti K; Harry Kane, M M; Rachimi, Suzanna S; Mani, D R DR; Gillette, Michael A MA; Satpathy, Shankha S; Clauser, Karl R KR; Udeshi, Namrata D ND; Carr, Steven A SA
Report of multiple high-grade gliomas in two patients with shared retained ATRX, wild-type IDH, losses of CDKN2A genes and alterations in the PTEN-PI3K axis.
Journal Of Surgical Case Reports
Khatchadourian, Christopher C; Guo, Jin J; Prasad, Chaya J CJ; Orlando, Robert A RA; Parsa, Cyrus C
Deep genomic characterization highlights complexities and prognostic markers of pediatric acute myeloid leukemia.
Communications Biology
Cheng, Chi-Keung CK; Yung, Yuk-Lin YL; Chan, Hoi-Yun HY; Leung, Kam-Tong KT; Chan, Kathy Y Y KYY; Leung, Alex W K AWK; Cheng, Frankie W T FWT; Li, Chi-Kong CK; Wan, Thomas S K TSK; Luo, Xi X; Pitts, Herbert-Augustus HA; Cheung, Joyce S JS; Chan, Natalie P H NPH; Ng, Margaret H L MHL
Publication Date: 2023-03-31
Variant appearance in text: IDH1: 395G>A; R132H; rs121913500
Multicenter Phase II Trial of the PARP Inhibitor Olaparib in Recurrent IDH1- and IDH2-mutant Glioma.
Cancer Research Communications
Fanucci, Kristina K; Pilat, Mary Jo MJ; Shyr, Derek D; Shyr, Yu Y; Boerner, Scott S; Li, Jing J; Durecki, Diane D; Drappatz, Jan J; Puduvalli, Vinay V; Lieberman, Frank Scott FS; Gonzalez, Javier J; Giglio, Pierre P; Ivy, S Percy SP; Bindra, Ranjit S RS; Omuro, Antonio A; LoRusso, Patricia P
Update for astrocytomas: medical and surgical management considerations.
Exploration Of Neuroscience
Willman, Matthew M; Willman, Jonathan J; Figg, John J; Dioso, Emma E; Sriram, Sai S; Olowofela, Bankole B; Chacko, Kevin K; Hernandez, Jairo J; Lucke-Wold, Brandon B
Multiomic neuropathology improves diagnostic accuracy in pediatric neuro-oncology.
Nature Medicine
Sturm, Dominik D; Capper, David D; Andreiuolo, Felipe F; Gessi, Marco M; Kölsche, Christian C; Reinhardt, Annekathrin A; Sievers, Philipp P; Wefers, Annika K AK; Ebrahimi, Azadeh A; Suwala, Abigail K AK; Gielen, Gerrit H GH; Sill, Martin M; Schrimpf, Daniel D; Stichel, Damian D; Hovestadt, Volker V; Daenekas, Bjarne B; Rode, Agata A; Hamelmann, Stefan S; Previti, Christopher C; Jäger, Natalie N; Buchhalter, Ivo I; Blattner-Johnson, Mirjam M; Jones, Barbara C BC; Warmuth-Metz, Monika M; Bison, Brigitte B; Grund, Kerstin K; Sutter, Christian C; Hirsch, Steffen S; Dikow, Nicola N; Hasselblatt, Martin M; Schüller, Ulrich U; Gerber, Nicolas U NU; White, Christine L CL; Buntine, Molly K MK; Kinross, Kathryn K; Algar, Elizabeth M EM; Hansford, Jordan R JR; Gottardo, Nicholas G NG; Hernáiz Driever, Pablo P; Gnekow, Astrid A; Witt, Olaf O; Müller, Hermann L HL; Calaminus, Gabriele G; Fleischhack, Gudrun G; Kordes, Uwe U; Mynarek, Martin M; Rutkowski, Stefan S; Frühwald, Michael C MC; Kramm, Christof M CM; von Deimling, Andreas A; Pietsch, Torsten T; Sahm, Felix F; Pfister, Stefan M SM; Jones, David T W DTW