Publications:

Mutations of R882 change flanking sequence preferences of the DNA methyltransferase DNMT3A and cellular methylation patterns.

Nucleic Acids Research

Emperle, Max M; Adam, Sabrina S; Kunert, Stefan S; Dukatz, Michael M; Baude, Annika A; Plass, Christoph C; Rathert, Philipp P; Bashtrykov, Pavel P; Jeltsch, Albert A

Publication Date: 2019-12-02

Variant appearance in text: DNMT3A: R882A

PubMed Link: 31620784

Variant Present in the following documents:

• Main text
• gkz911.pdf

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The DNMT3A R882H mutant displays altered flanking sequence preferences.

Nucleic Acids Research

Emperle, Max M; Rajavelu, Arumugam A; Kunert, Stefan S; Arimondo, Paola B PB; Reinhardt, Richard R; Jurkowska, Renata Z RZ; Jeltsch, Albert A

Publication Date: 2018-04-06

Variant appearance in text: DNMT3A: R882A

PubMed Link: 29518238

Variant Present in the following documents:

• Main text
• gky168.pdf

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Persistence of DNMT3A R882 mutations during remission does not adversely affect outcomes of patients with acute myeloid leukaemia.

British Journal Of Haematology

Bhatnagar, Bhavana B; Eisfeld, Ann-Kathrin AK; Nicolet, Deedra D; Mrózek, Krzysztof K; Blachly, James S JS; Orwick, Shelley S; Lucas, David M DM; Kohlschmidt, Jessica J; Blum, William W; Kolitz, Jonathan E JE; Stone, Richard M RM; Bloomfield, Clara D CD; Byrd, John C JC

Publication Date: 2016-10

Variant appearance in text: DNMT3A: R882A

PubMed Link: 27476855

Variant Present in the following documents:

• Main text

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Mutations in epigenetic modifiers in myeloid malignancies and the prospect of novel epigenetic-targeted therapy.

Advances In Hematology

Fathi, Amir T AT; Abdel-Wahab, Omar O

Publication Date: 2012

Variant appearance in text: DNMT3A: R882A

PubMed Link: 21811504

Variant Present in the following documents:

• Main text
• AH2012-469592.pdf

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