DNMT3A c.2521A>G ;(p.K841E)

Variant ID: 2-25458652-T-C

NM_022552.4(DNMT3A):c.2521A>G;(p.K841E)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Genomic Landscape in Neoplasm-Like Stroma Reveals Distinct Prognostic Subtypes of Pancreatic Ductal Adenocarcinoma.

Frontiers In Oncology
Jiang, Jiahong J; Xu, Yaping Y; Chang, Lianpeng L; Ru, Guoqing G; Xia, Xuefeng X; Yang, Ling L; Yi, Xin X; Chen, Zheling Z; Huang, Dong-Sheng DS; Yang, Liu L
Publication Date: 2021

Variant appearance in text: DNMT3A: 2521A>G; K841E
PubMed Link: 34733795
Variant Present in the following documents:
  • Table_1.xlsx, sheet 1
View BVdb publication page



High-intensity sequencing reveals the sources of plasma circulating cell-free DNA variants.

Nature Medicine
Razavi, Pedram P; Li, Bob T BT; Brown, David N DN; Jung, Byoungsok B; Hubbell, Earl E; Shen, Ronglai R; Abida, Wassim W; Juluru, Krishna K; De Bruijn, Ino I; Hou, Chenlu C; Venn, Oliver O; Lim, Raymond R; Anand, Aseem A; Maddala, Tara T; Gnerre, Sante S; Vijaya Satya, Ravi R; Liu, Qinwen Q; Shen, Ling L; Eattock, Nicholas N; Yue, Jeanne J; Blocker, Alexander W AW; Lee, Mark M; Sehnert, Amy A; Xu, Hui H; Hall, Megan P MP; Santiago-Zayas, Angie A; Novotny, William F WF; Isbell, James M JM; Rusch, Valerie W VW; Plitas, George G; Heerdt, Alexandra S AS; Ladanyi, Marc M; Hyman, David M DM; Jones, David R DR; Morrow, Monica M; Riely, Gregory J GJ; Scher, Howard I HI; Rudin, Charles M CM; Robson, Mark E ME; Diaz, Luis A LA; Solit, David B DB; Aravanis, Alexander M AM; Reis-Filho, Jorge S JS
Publication Date: 2019-12

Variant appearance in text: DNMT3A: 2521A>G; K841E
PubMed Link: 31768066
Variant Present in the following documents:
  • NIHMS1541314-supplement-1541314_Sup_Tab.xlsx, sheet 4
  • NIHMS1541314-supplement-1541314_SourceDataExtFig8.xlsx, sheet 1
  • NIHMS1541314-supplement-1541314_Sup_Tab.xlsx, sheet 5
View BVdb publication page



The global clonal complexity of the murine blood system declines throughout life and after serial transplantation.

Blood
Ganuza, Miguel M; Hall, Trent T; Finkelstein, David D; Wang, Yong-Dong YD; Chabot, Ashley A; Kang, Guolian G; Bi, Wenjian W; Wu, Gang G; McKinney-Freeman, Shannon S
Publication Date: 2019-05-02

Variant appearance in text: DNMT3A: 2521A>G; Lys841Glu
PubMed Link: 30782612
Variant Present in the following documents:
  • Main text
View BVdb publication page



Clinical resistance to crenolanib in acute myeloid leukemia due to diverse molecular mechanisms.

Nature Communications
Zhang, Haijiao H; Savage, Samantha S; Schultz, Anna Reister AR; Bottomly, Daniel D; White, Libbey L; Segerdell, Erik E; Wilmot, Beth B; McWeeney, Shannon K SK; Eide, Christopher A CA; Nechiporuk, Tamilla T; Carlos, Amy A; Henson, Rachel R; Lin, Chenwei C; Searles, Robert R; Ho, Hoang H; Lam, Yee Ling YL; Sweat, Richard R; Follit, Courtney C; Jain, Vinay V; Lind, Evan E; Borthakur, Gautam G; Garcia-Manero, Guillermo G; Ravandi, Farhad F; Kantarjian, Hagop M HM; Cortes, Jorge J; Collins, Robert R; Buelow, Daelynn R DR; Baker, Sharyn D SD; Druker, Brian J BJ; Tyner, Jeffrey W JW
Publication Date: 2019-01-16

Variant appearance in text: DNMT3A: K841E
PubMed Link: 30651561
Variant Present in the following documents:
  • 41467_2018_8263_MOESM5_ESM.xlsx, sheet 1
View BVdb publication page



Structural basis for DNMT3A-mediated de novo DNA methylation.

Nature
Zhang, Zhi-Min ZM; Lu, Rui R; Wang, Pengcheng P; Yu, Yang Y; Chen, Dongliang D; Gao, Linfeng L; Liu, Shuo S; Ji, Debin D; Rothbart, Scott B SB; Wang, Yinsheng Y; Wang, Gang Greg GG; Song, Jikui J
Publication Date: 2018-02-15

Variant appearance in text: DNMT3A: K841E
PubMed Link: 29414941
Variant Present in the following documents:
  • Main text
  • nihms930180.pdf
View BVdb publication page