Publications:

The MECP2-TRD domain interacts with the DNMT3A-ADD domain at the H3-tail binding site.

Protein Science : A Publication Of The Protein Society

Kunert, Stefan S; Linhard, Verena V; Weirich, Sara S; Choudalakis, Michel M; Osswald, Florian F; Krämer, Lisa L; Köhler, Anja R AR; Bröhm, Alexander A; Wollenhaupt, Jan J; Schwalbe, Harald H; Jeltsch, Albert A

Publication Date: 2022-12-15

Variant appearance in text: DNMT3A: D529A

PubMed Link: 36519786

Variant Present in the following documents:

• Main text
• PRO-32-e4542.pdf

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Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity.

Science Advances

Chen, Xiufei X; Zhou, Wenjie W; Song, Ren-Hua RH; Liu, Shuang S; Wang, Shu S; Chen, Yujia Y; Gao, Chao C; He, Chenxi C; Xiao, Jianxiong J; Zhang, Lei L; Wang, Tianxiang T; Liu, Peng P; Duan, Kunlong K; Cheng, Zhouli Z; Zhang, Chen C; Zhang, Jinye J; Sun, Yiping Y; Jackson, Felix F; Lan, Fei F; Liu, Yun Y; Xu, Yanhui Y; Wong, Justin Jong-Leong JJ; Wang, Pu P; Yang, Hui H; Xiong, Yue Y; Chen, Tong T; Li, Yan Y; Ye, Dan D

Publication Date: 2022-01-28

Variant appearance in text: DNMT3A: D529A

PubMed Link: 35080973

Variant Present in the following documents:

• Main text
• sciadv.abl5220.pdf
• sciadv.abl5220_sm.pdf

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Tumor suppressor CEBPA interacts with and inhibits DNMT3A activity.

Science Advances

Chen, Xiufei X; Zhou, Wenjie W; Song, Ren-Hua RH; Liu, Shuang S; Wang, Shu S; Chen, Yujia Y; Gao, Chao C; He, Chenxi C; Xiao, Jianxiong J; Zhang, Lei L; Wang, Tianxiang T; Liu, Peng P; Duan, Kunlong K; Cheng, Zhouli Z; Zhang, Chen C; Zhang, Jinye J; Sun, Yiping Y; Jackson, Felix F; Lan, Fei F; Liu, Yun Y; Xu, Yanhui Y; Wong, Justin Jong-Leong JJ; Wang, Pu P; Yang, Hui H; Xiong, Yue Y; Chen, Tong T; Li, Yan Y; Ye, Dan D

Publication Date: 2022-01-28

Variant appearance in text: DNMT3A: D529A

PubMed Link: 35080973

Variant Present in the following documents:

• Main text
• sciadv.abl5220.pdf
• sciadv.abl5220_sm.pdf

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A Model System for Studying the DNMT3A Hotspot Mutation (DNMT3AR882) Demonstrates a Causal Relationship between Its Dominant-Negative Effect and Leukemogenesis.

Cancer Research

Lu, Rui R; Wang, Jun J; Ren, Zhihong Z; Yin, Jiekai J; Wang, Yinsheng Y; Cai, Ling L; Wang, Gang Greg GG

Publication Date: 2019-07-15

Variant appearance in text: DNMT3A: D529A

PubMed Link: 31164355

Variant Present in the following documents:

• Main text

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Effect of Disease-Associated Germline Mutations on Structure Function Relationship of DNA Methyltransferases.

Genes

Norvil, Allison B AB; Saha, Debapriya D; Dar, Mohd Saleem MS; Gowher, Humaira H

Publication Date: 2019-05-14

Variant appearance in text: DNMT3A: Asp529Ala

PubMed Link: 31091831

Variant Present in the following documents:

• Main text
• genes-10-00369.pdf

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