DNMT3A c.1421G>A ;(p.R474H)

Variant ID: 2-25469037-C-T

NM_022552.4(DNMT3A):c.1421G>A;(p.R474H)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Clinical impact of clonal hematopoiesis on severe COVID-19 patients without canonical risk factors.

Haematologica
Kang, Chang Kyung CK; Choi, Baekgyu B; Kim, Sugyeong S; Sun, Choong Hyun CH; Yoon, Soon Ho SH; Kim, Kyukwang K; Chang, Euijin E; Jung, Jongtak J; Choe, Pyoeng Gyun PG; Park, Wan Beom WB; Kim, Eu Suk ES; Kim, Hong Bin HB; Kim, Nam Joong NJ; Oh, Myoung-Don MD; Im, Hogune H; Kim, Joohae J; Lee, Yong Hoon YH; Lee, Jaehee J; Chun, Hyonho H; Koh, Youngil Y; Lee, Ji Yeon JY; Moon, Joon Ho JH; Song, Kyoung-Ho KH; Jung, Inkyung I
Publication Date: 2022-09-15

Variant appearance in text: DNMT3A: 1421G>A; Arg474His
PubMed Link: 36106393
Variant Present in the following documents:
  • 2022_280621_KANG_SUPPL.pdf
View BVdb publication page



Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer.

Frontiers In Oncology
Yu, Haipeng H; Xu, Yan Y; Gao, Wei W; Li, Mei M; He, Ji'an J; Deng, Xiaoqian X; Xing, Wenge W
Publication Date: 2022

Variant appearance in text: DNMT3A: R474H
PubMed Link: 36072793
Variant Present in the following documents:
  • Table_3.xlsx, sheet 1
View BVdb publication page



Redefine Hyperprogressive Disease During Treatment With Immune-Checkpoint Inhibitors in Patients With Gastrointestinal Cancer.

Frontiers In Oncology
Wang, Zhenghang Z; Liu, Chang C; Bai, Yuezong Y; Zhao, Xiaochen X; Cui, Longgang L; Peng, Zhi Z; Zhang, Xiaotian X; Wang, Xicheng X; Zhao, Zhengyi Z; Li, Jian J; Shen, Lin L
Publication Date: 2021

Variant appearance in text: DNMT3A: R474H
PubMed Link: 34858840
Variant Present in the following documents:
  • Table_2.xlsx, sheet 1
View BVdb publication page



Comprehensive next-generation profiling of clonal hematopoiesis in cancer patients using paired tumor-blood sequencing for guiding personalized therapies.

Clinical And Translational Medicine
Li, Ziyang Z; Huang, Wensou W; Yin, Jiani C JC; Na, Chenglong C; Wu, Xue X; Shao, Yang Y; Ding, Huaxin H; Li, Jinming J
Publication Date: 2020-11

Variant appearance in text: DNMT3A: 1421G>A; R474H
PubMed Link: 33252848
Variant Present in the following documents:
  • CTM2-10-e222-s003.xlsx, sheet 1
View BVdb publication page