DNMT3A c.1227G>T ;(p.W409C)

Variant ID: 2-25469541-C-A

NM_022552.4(DNMT3A):c.1227G>T;(p.W409C)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Short-term dynamics of circulating tumor DNA predicting efficacy of sintilimab plus docetaxel in second-line treatment of advanced NSCLC: biomarker analysis from a single-arm, phase 2 trial.

Journal For Immunotherapy Of Cancer
Han, Xiao X; Tang, Xiaoyong X; Zhu, Hui H; Zhu, Dongyuan D; Zhang, Xiqin X; Meng, Xiangjiao X; Hua, Ying Y; Wang, Zhongtang Z; Zhang, Yan Y; Huang, Wei W; Wang, Linlin L; Yuan, Shuanghu S; Zhang, Pinliang P; Gong, Heyi H; Sun, Yulan Y; Zhang, Yingjie Y; Liu, Zengjun Z; Dong, Xiaomeng X; Gai, Fei F; Huang, Zhan Z; Zhu, Changbin C; Guo, Jun J; Wang, Zhehai Z
Publication Date: 2022-12

Variant appearance in text: DNMT3A: 1227G>T; W409C
PubMed Link: 36600554
Variant Present in the following documents:
  • jitc-2022-004952supp005.pdf
View BVdb publication page



Predictive mutation signature of immunotherapy benefits in NSCLC based on machine learning algorithms.

Frontiers In Immunology
Liu, Zhichao Z; Lin, Guo G; Yan, Zeping Z; Li, Linduo L; Wu, Xingchen X; Shi, Jingrong J; He, Jianxing J; Zhao, Lei L; Liang, Hengrui H; Wang, Wei W
Publication Date: 2022

Variant appearance in text: DNMT3A: 1227G>T; W409C
PubMed Link: 36238300
Variant Present in the following documents:
  • Table_1.xlsx, sheet 4
View BVdb publication page



EPHA5 mutation was associated with adverse outcome of atezolizumab treatment in late-stage non-small cell lung cancers.

Bmc Pulmonary Medicine
Li, Zhenxiang Z; Zhou, Qing Q; Wang, Qi Q; Wang, Haiyong H; Yue, Weiming W
Publication Date: 2022-09-19

Variant appearance in text: DNMT3A: 1227G>T; W409C
PubMed Link: 36123678
Variant Present in the following documents:
  • 12890_2022_2161_MOESM2_ESM.xlsx, sheet 1
View BVdb publication page