Publications:

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Understanding and targeting resistance mechanisms in cancer.

Medcomm

Lei, Zi-Ning ZN; Tian, Qin Q; Teng, Qiu-Xu QX; Wurpel, John N D JND; Zeng, Leli L; Pan, Yihang Y; Chen, Zhe-Sheng ZS

Publication Date: 2023-06

Variant appearance in text: ALK: S1206Y

PubMed Link: 37229486

Variant Present in the following documents:

• Main text
• MCO2-4-e265.pdf

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Biology and impact of lineage plasticity in ALK-positive NSCLC: a narrative review.

Translational Lung Cancer Research

Meador, Catherine B CB; Piotrowska, Zofia Z

Publication Date: 2023-04-28

Variant appearance in text: ALK: S1206Y

PubMed Link: 37197622

Variant Present in the following documents:

• tlcr-12-04-837.pdf

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EML4-ALK biology and drug resistance in Non-Small Cell Lung Cancer: a new phase of discoveries.

Molecular Oncology

Elshatlawy, Mariam M; Sampson, Josephina J; Clarke, Katy K; Bayliss, Richard R

Publication Date: 2023-05-07

Variant appearance in text: ALK: S1206Y

PubMed Link: 37149843

Variant Present in the following documents:

• MOL2-17-950.pdf

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Iruplinalkib (WX‑0593), a novel ALK/ROS1 inhibitor, overcomes crizotinib resistance in preclinical models for non-small cell lung cancer.

Investigational New Drugs

Yang, Yingying Y; Zheng, Qingmei Q; Wang, Xinmei X; Zhao, Shuyong S; Huang, Wenshu W; Jia, Linchao L; Ma, Cuicui C; Liu, Shicong S; Zhang, Yongpeng Y; Xin, Qianqian Q; Sun, Yan Y; Zheng, Shansong S

Publication Date: 2023-04-10

Variant appearance in text: ALK: S1206Y

PubMed Link: 37036582

Variant Present in the following documents:

• Main text
• 10637_2023_Article_1350.pdf

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Molecular Anatomy of the EML4-ALK Fusion Protein for the Development of Novel Anticancer Drugs.

International Journal Of Molecular Sciences

Cheon, So Yeong SY; Kwon, Sunghark S

Publication Date: 2023-03-18

Variant appearance in text: ALK: S1206Y

PubMed Link: 36982897

Variant Present in the following documents:

• Main text
• ijms-24-05821.pdf

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Recent progress in targeted therapy for non-small cell lung cancer.

Frontiers In Pharmacology

Xiao, Yanxia Y; Liu, Pu P; Wei, Jie J; Zhang, Xin X; Guo, Jun J; Lin, Yajun Y

Publication Date: 2023

Variant appearance in text: ALK: S1206Y

PubMed Link: 36909198

Variant Present in the following documents:

• Main text
• fphar-14-1125547.pdf

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Ensartinib in advanced ALK-positive non-small cell lung cancer: a multicenter, open-label, two-staged, phase 1 trial.

Journal Of Thoracic Disease

Ma, Yuxiang Y; Pan, Hui H; Liu, Yu Y; Zhang, Yang Y; Hong, Shaodong S; Huang, Jianjin J; Weng, Shanshan S; Yang, Yunpeng Y; Fang, Wenfeng W; Huang, Yan Y; Xiao, Shanshan S; Wang, Tao T; Ding, Lieming L; Cui, Lingling L; Zhang, Li L; Zhao, Hongyun H

Publication Date: 2022-12

Variant appearance in text: ALK: S1206Y

PubMed Link: 36647478

Variant Present in the following documents:

• Main text
• jtd-14-12-4751.pdf

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Molecular pathways, resistance mechanisms and targeted interventions in non-small-cell lung cancer.

Molecular Biomedicine

Wang, Zixi Z; Xing, Yurou Y; Li, Bingjie B; Li, Xiaoyu X; Liu, Bin B; Wang, Yongsheng Y

Publication Date: 2022-12-12

Variant appearance in text: ALK: S1206Y

PubMed Link: 36508072

Variant Present in the following documents:

• Main text
• 43556_2022_Article_107.pdf

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Ceritinib (LDK378) prevents bone loss via suppressing Akt and NF-κB-induced osteoclast formation.

Frontiers In Endocrinology

He, Wenxin W; Cao, Xiankun X; Kong, Keyu K; Rong, Kewei K; Han, Shuai S; Qin, An A

Publication Date: 2022

Variant appearance in text: ALK: Ser1206Tyr

PubMed Link: 36425467

Variant Present in the following documents:

• Main text
• fendo-13-939959.pdf

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Case report: BRAF A598-T599insV mutation as a potential resistance mechanism to alectinib in ALK-rearranged lung adenocarcinoma.

Frontiers In Oncology

Pasau, Thomas T; Wauters, Els E; Wauters, Isabelle I; Duplaquet, Fabrice F; Pirard, Lionel L; Pop-Stanciu, Claudia C; D'Haene, Nicky N; Dupont, Michael M; Vander Borght, Thierry T; Rondelet, Benoît B; Ocak, Sebahat S

Publication Date: 2022

Variant appearance in text: ALK: S1206Y

PubMed Link: 36419902

Variant Present in the following documents:

• Main text
• fonc-12-985446.pdf

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The Overview of Perspectives of Clinical Application of Liquid Biopsy in Non-Small-Cell Lung Cancer.

Life (Basel, Switzerland)

Bożyk, Aleksandra A; Nicoś, Marcin M

Publication Date: 2022-10-19

Variant appearance in text: ALK: S1206Y

PubMed Link: 36295075

Variant Present in the following documents:

• Main text
• life-12-01640.pdf

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Small-molecule inhibitors, immune checkpoint inhibitors, and more: FDA-approved novel therapeutic drugs for solid tumors from 1991 to 2021.

Journal Of Hematology & Oncology

Wu, Qing Q; Qian, Wei W; Sun, Xiaoli X; Jiang, Shaojie S

Publication Date: 2022-10-08

Variant appearance in text: ALK: S1206Y

PubMed Link: 36209184

Variant Present in the following documents:

• Main text
• 13045_2022_Article_1362.pdf

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Fibroblast growth factor receptor 3 overexpression mediates ALK inhibitor resistance in ALK-rearranged non-small cell lung cancer.

Cancer Science

Sakashita, Takuya T; Yanagitani, Noriko N; Koike, Sumie S; Low, Siew-Kee SK; Takagi, Satoshi S; Baba, Satoko S; Takeuchi, Kengo K; Nishio, Makoto M; Fujita, Naoya N; Katayama, Ryohei R

Publication Date: 2022-11

Variant appearance in text: ALK: S1206Y

PubMed Link: 35950895

Variant Present in the following documents:

• CAS-113-3888-s002.pdf

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Discovery of a novel ALK/ROS1/FAK inhibitor, APG-2449, in preclinical non-small cell lung cancer and ovarian cancer models.

Bmc Cancer

Fang, Douglas D DD; Tao, Ran R; Wang, Guangfeng G; Li, Yuanbao Y; Zhang, Kaixiang K; Xu, Chunhua C; Zhai, Guoqin G; Wang, Qixin Q; Wang, Jingwen J; Tang, Chunyang C; Min, Ping P; Xiong, Dengkun D; Chen, Jianyong J; Wang, Shaomeng S; Yang, Dajun D; Zhai, Yifan Y

Publication Date: 2022-07-11

Variant appearance in text: ALK: S1206Y

PubMed Link: 35820889

Variant Present in the following documents:

• Main text
• 12885_2022_Article_9799.pdf

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AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery

Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,

Publication Date: 2022-09-02

Variant appearance in text: ALK: S1206Y

PubMed Link: 35819403

Variant Present in the following documents:

• cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1

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Latest perspectives of orally bioavailable 2,4-diarylaminopyrimidine analogues (DAAPalogues) as anaplastic lymphoma kinase inhibitors: discovery and clinical developments.

Rsc Advances

Latif, Muhammad M; Ashraf, Zaman Z; Basit, Sulman S; Ghaffar, Abdul A; Zafar, Muhammad Sohail MS; Saeed, Aamer A; Meo, Sultan Ayoub SA

Publication Date: 2018-05-03

Variant appearance in text: ALK: S1206Y

PubMed Link: 35540549

Variant Present in the following documents:

• Main text
• RA-008-C8RA01934G.pdf

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Targeting ALK Rearrangements in NSCLC: Current State of the Art.

Frontiers In Oncology

Peng, Ling L; Zhu, Liping L; Sun, Yilan Y; Stebbing, Justin J; Selvaggi, Giovanni G; Zhang, Yongchang Y; Yu, Zhentao Z

Publication Date: 2022

Variant appearance in text: ALK: S1206Y

PubMed Link: 35463328

Variant Present in the following documents:

• Main text
• fonc-12-863461.pdf

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Culture and multiomic analysis of lung cancer patient-derived pleural effusions revealed distinct druggable molecular types.

Scientific Reports

Seo, Ha-Young HY; Kim, Soon-Chan SC; Roh, Woo-Lee WL; Shin, Young-Kyoung YK; Kim, Soyeon S; Kim, Dong-Wan DW; Kim, Tae Min TM; Ku, Ja-Lok JL

Publication Date: 2022-04-15

Variant appearance in text: ALK: S1206Y

PubMed Link: 35428753

Variant Present in the following documents:

• Main text
• 41598_2022_Article_10318.pdf

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Successful treatment of refractory brain metastases from ALK-positive lung cancer with lorlatinib.

Thoracic Cancer

Nakagawa, Yoshiko Y; Shimizu, Tetsuo T; Hiranuma, Hisato H; Gon, Yasuhiro Y

Publication Date: 2022-05

Variant appearance in text: ALK: S1206Y

PubMed Link: 35373538

Variant Present in the following documents:

• Main text
• TCA-13-1431.pdf

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Crizotinib in patients with tumors harboring ALK or ROS1 rearrangements in the NCI-MATCH trial.

Npj Precision Oncology

Mansfield, A S AS; Wei, Z Z; Mehra, R R; Shaw, A T AT; Lieu, C H CH; Forde, P M PM; Drilon, A E AE; Mitchell, E P EP; Wright, J J JJ; Takebe, N N; Sharon, E E; Hovelson, D D; Tomlins, S S; Zeng, J J; Poorman, K K; Malik, N N; Gray, R J RJ; Li, S S; McShane, L M LM; Rubinstein, L V LV; Patton, D D; Williams, P M PM; Hamilton, S R SR; Conley, B A BA; Arteaga, C L CL; Harris, L N LN; O'Dwyer, P J PJ; Chen, A P AP; Flaherty, K T KT

Publication Date: 2022-03-01

Variant appearance in text: ALK: S1206Y

PubMed Link: 35233056

Variant Present in the following documents:

• Main text

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: ALK: S1206Y

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: ALK: Ser1206Tyr

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

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Deciphering the Mechanism of Gilteritinib Overcoming Lorlatinib Resistance to the Double Mutant I1171N/F1174I in Anaplastic Lymphoma Kinase.

Frontiers In Cell And Developmental Biology

Liang, Shuai S; Wang, Qing Q; Qi, Xuesen X; Liu, Yudi Y; Li, Guozhen G; Lu, Shaoyong S; Mou, Linkai L; Chen, Xiangyu X

Publication Date: 2021

Variant appearance in text: ALK: S1206Y

PubMed Link: 35004700

Variant Present in the following documents:

• Main text

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Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.

Medcomm

Cheng, Yuan Y; Zhang, Tao T; Xu, Qing Q

Publication Date: 2021-12

Variant appearance in text: ALK: S1206Y

PubMed Link: 34977873

Variant Present in the following documents:

• Main text
• MCO2-2-692.pdf

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Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers

Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD

Publication Date: 2021-11-29

Variant appearance in text: ALK: S1206Y

PubMed Link: 34885113

Variant Present in the following documents:

• Main text

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Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers

Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD

Publication Date: 2021-11-29

Variant appearance in text: ALK: S1206Y

PubMed Link: 34885113

Variant Present in the following documents:

• Main text

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A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC.

Embo Molecular Medicine

Lu, Yue Y; Fan, Zhenzhen Z; Zhu, Su-Jie SJ; Huang, Xiaoxing X; Zhuang, Zhongji Z; Li, Yunzhan Y; Deng, Zhou Z; Gao, Lei L; Hong, Xuehui X; Zhang, Ting T; Li, Li L; Sun, Xihuan X; Huang, Wei W; Zhang, Jingfang J; Liu, Yan Y; Zhang, Baoding B; Jiang, Jie J; Gui, Fu F; Wang, Zheng Z; Li, Qiyuan Q; Song, Siyang S; Huang, Xin X; Wu, Qiao Q; Chen, Lanfen L; Zhou, Dawang D; Zhang, Jianming J; Yun, Cai-Hong CH; Chen, Liang L; Deng, Xianming X

Publication Date: 2022-01-11

Variant appearance in text: ALK: S1206Y

PubMed Link: 34845836

Variant Present in the following documents:

• Main text
• EMMM-14-e14296.pdf
• EMMM-14-e14296-s001.pdf

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A new ALK inhibitor overcomes resistance to first- and second-generation inhibitors in NSCLC.

Embo Molecular Medicine

Lu, Yue Y; Fan, Zhenzhen Z; Zhu, Su-Jie SJ; Huang, Xiaoxing X; Zhuang, Zhongji Z; Li, Yunzhan Y; Deng, Zhou Z; Gao, Lei L; Hong, Xuehui X; Zhang, Ting T; Li, Li L; Sun, Xihuan X; Huang, Wei W; Zhang, Jingfang J; Liu, Yan Y; Zhang, Baoding B; Jiang, Jie J; Gui, Fu F; Wang, Zheng Z; Li, Qiyuan Q; Song, Siyang S; Huang, Xin X; Wu, Qiao Q; Chen, Lanfen L; Zhou, Dawang D; Zhang, Jianming J; Yun, Cai-Hong CH; Chen, Liang L; Deng, Xianming X

Publication Date: 2021-11-30

Variant appearance in text: ALK: S1206Y

PubMed Link: 34845836

Variant Present in the following documents:

• Main text
• EMMM-14-e14296.pdf
• EMMM-14-e14296-s001.pdf

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Evaluation of the MGISEQ-2000 Sequencing Platform for Illumina Target Capture Sequencing Libraries.

Frontiers In Genetics

Lang, Jidong J; Zhu, Rongrong R; Sun, Xue X; Zhu, Siyu S; Li, Tianbao T; Shi, Xiaoli X; Sun, Yanqi Y; Yang, Zhou Z; Wang, Weiwei W; Bing, Pingping P; He, Binsheng B; Tian, Geng G

Publication Date: 2021

Variant appearance in text: ALK: S1206Y

PubMed Link: 34777467

Variant Present in the following documents:

• DataSheet1.xlsx, sheet 4

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Predictive and Prognostic Biomarkers for Lung Cancer Bone Metastasis and Their Therapeutic Value.

Frontiers In Oncology

Chai, Xupeng X; Yinwang, Eloy E; Wang, Zenan Z; Wang, Zhan Z; Xue, Yucheng Y; Li, Binghao B; Zhou, Hao H; Zhang, Wenkan W; Wang, Shengdong S; Zhang, Yongxing Y; Li, Hengyuan H; Mou, Haochen H; Sun, Lingling L; Qu, Hao H; Wang, Fangqian F; Zhang, Zengjie Z; Chen, Tao T; Ye, Zhaoming Z

Publication Date: 2021

Variant appearance in text: ALK: S1206Y

PubMed Link: 34722241

Variant Present in the following documents:

• Main text
• fonc-11-692788.pdf

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The Resistance Mechanisms and Treatment Strategies for ALK-Rearranged Non-Small Cell Lung Cancer.

Frontiers In Oncology

Pan, Yue Y; Deng, Chao C; Qiu, Zhenhua Z; Cao, Chenghui C; Wu, Fang F

Publication Date: 2021

Variant appearance in text: ALK: S1206Y

PubMed Link: 34660278

Variant Present in the following documents:

• Main text

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ALK: S1206Y

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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A Novel Sequentially Evolved EML4-ALK Variant 3 G1202R/S1206Y Double Mutation In Cis Confers Resistance to Lorlatinib: A Brief Report and Literature Review.

Jto Clinical And Research Reports

Zhu, Viola W VW; Nagasaka, Misako M; Madison, Russell R; Schrock, Alexa B AB; Cui, Jean J; Ou, Sai-Hong Ignatius SI

Publication Date: 2021-01

Variant appearance in text: ALK: S1206Y

PubMed Link: 34589977

Variant Present in the following documents:

• Main text
• main.pdf

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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: ALK: S1206Y

PubMed Link: 34440110

Variant Present in the following documents:

• Main text
• biomedicines-09-00906.pdf

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Update on molecular pathology and role of liquid biopsy in nonsmall cell lung cancer.

European Respiratory Review : An Official Journal Of The European Respiratory Society

Abdayem, Pamela P; Planchard, David D

Publication Date: 2021-09-30

Variant appearance in text: ALK: S1206Y

PubMed Link: 34289984

Variant Present in the following documents:

• Main text
• ERR-0294-2020.pdf

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One-Step Polymerase Chain Reaction-Free Nanowire-Based Plasma Cell-Free DNA Assay to Detect EML4-ALK Fusion and to Monitor Resistance in Lung Cancer.

The Oncologist

Lee, Youngjoo Y; Cho, Youngnam Y; Park, Eun Young EY; Park, Seong-Yun SY; Hwang, Kum Hui KH; Han, Ji-Youn JY

Publication Date: 2021-10

Variant appearance in text: ALK: S1206Y

PubMed Link: 34272914

Variant Present in the following documents:

• ONCO-26-e1683-s002.pdf

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Response to lorlatinib on a patient with ALK-rearranged non-small cell lung cancer harboring 1151Tins mutation with uterine metastasis.

Thoracic Cancer

Kobayashi, Takashi T; Kanda, Shintaro S; Fukushima, Toshirou T; Noguchi, Takuro T; Sekiguchi, Nodoka N; Koizumi, Tomonobu T

Publication Date: 2021-08

Variant appearance in text: ALK: S1206Y

PubMed Link: 34184417

Variant Present in the following documents:

• Main text
• TCA-12-2275.pdf

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Appropriate use of cancer comprehensive genome profiling assay using circulating tumor DNA.

Cancer Science

Sunami, Kuniko K; Bando, Hideaki H; Yatabe, Yasushi Y; Naito, Yoichi Y; Takahashi, Hideaki H; Tsuchihara, Katsuya K; Toyooka, Shinichi S; Mimori, Koshi K; Kohsaka, Shinji S; Uetake, Hiroyuki H; Kinoshita, Ichiro I; Komine, Keigo K; Takeda, Masayuki M; Hayashida, Tetsu T; Tamura, Kenji K; Nishio, Kazuto K; Yamamoto, Noboru N; ,

Publication Date: 2021-09

Variant appearance in text: ALK: S1206Y

PubMed Link: 34128569

Variant Present in the following documents:

• Main text

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Pathological complete response to neoadjuvant ceritinib of a crizotinib-resistant, stage IIIB non-small cell lung cancer with ALK rearrangement: A case report.

Thoracic Cancer

Bing, Zhongxing Z; Jia, Ziqi Z; Wang, Yadong Y; Xue, Jianchao J; Cao, Lei L; Cao, Zhili Z; Liu, Peng P; Li, Ji J; Liang, Naixin N; Li, Shanqing S

Publication Date: 2021-07

Variant appearance in text: ALK: S1206Y

PubMed Link: 34105864

Variant Present in the following documents:

• Main text

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A review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma.

Journal Of Experimental & Clinical Cancer Research : Cr

Mlakar, Vid V; Morel, Edouard E; Mlakar, Simona Jurkovic SJ; Ansari, Marc M; Gumy-Pause, Fabienne F

Publication Date: 2021-06-08

Variant appearance in text: ALK: S1206Y

PubMed Link: 34103089

Variant Present in the following documents:

• Main text

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An insight into lung cancer: a comprehensive review exploring ALK TKI and mechanisms of resistance.

Bosnian Journal Of Basic Medical Sciences

Patcas, Adela A; Chis, Ana Florica AF; Militaru, Claudia Florentina CF; Bordea, Ioana Roxana IR; Rajnoveanu, Ruxandra R; Coza, Ovidiu Florin OF; Hanna, Reem R; Tiberiu, Tamas T; Todea, Doina Adina DA

Publication Date: 2022-02-01

Variant appearance in text: ALK: S1206Y

PubMed Link: 34082691

Variant Present in the following documents:

• Main text
• BJBMS-22-1.pdf

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Molecular Profiles of Brain Metastases: A Focus on Heterogeneity.

Cancers

Ali, Shan S; Górska, Zuzanna Z; Duchnowska, Renata R; Jassem, Jacek J

Publication Date: 2021-05-28

Variant appearance in text: ALK: S1206Y

PubMed Link: 34071176

Variant Present in the following documents:

• Main text

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Combining Radiation Therapy with ALK Inhibitors in Anaplastic Lymphoma Kinase-Positive Non-Small Cell Lung Cancer (NSCLC): A Clinical and Preclinical Overview.

Cancers

Antoni, Delphine D; Burckel, Hélène H; Noel, Georges G

Publication Date: 2021-05-15

Variant appearance in text: ALK: S1206Y

PubMed Link: 34063424

Variant Present in the following documents:

• Main text

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NGS-based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment.

Molecular Oncology

Sánchez-Herrero, Estela E; Serna-Blasco, Roberto R; Ivanchuk, Vadym V; García-Campelo, Rosario R; Dómine Gómez, Manuel M; Sánchez, José M JM; Massutí, Bartomeu B; Reguart, Noemi N; Camps, Carlos C; Sanz-Moreno, Sandra S; Calabuig-Fariñas, Silvia S; Jantus-Lewintre, Eloísa E; Arnal, Magdalena M; Fernández-Orth, Dietmar D; Calvo, Virginia V; González-Rumayor, Víctor V; Provencio, Mariano M; Romero, Atocha A

Publication Date: 2021-09

Variant appearance in text: ALK: 3617C>A; S1206Y

PubMed Link: 34058070

Variant Present in the following documents:

• Main text

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NGS-based liquid biopsy profiling identifies mechanisms of resistance to ALK inhibitors: a step toward personalized NSCLC treatment.

Molecular Oncology

Sánchez-Herrero, Estela E; Serna-Blasco, Roberto R; Ivanchuk, Vadym V; García-Campelo, Rosario R; Dómine Gómez, Manuel M; Sánchez, José M JM; Massutí, Bartomeu B; Reguart, Noemi N; Camps, Carlos C; Sanz-Moreno, Sandra S; Calabuig-Fariñas, Silvia S; Jantus-Lewintre, Eloísa E; Arnal, Magdalena M; Fernández-Orth, Dietmar D; Calvo, Virginia V; González-Rumayor, Víctor V; Provencio, Mariano M; Romero, Atocha A

Publication Date: 2021-09

Variant appearance in text: ALK: 3617C>A; S1206Y

PubMed Link: 34058070

Variant Present in the following documents:

• Main text

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Intratumoral Cellular Heterogeneity: Implications for Drug Resistance in Patients with Non-Small Cell Lung Cancer.

Cancers

Gregorc, Vanesa V; Lazzari, Chiara C; Mandalá, Mario M; Ippati, Stefania S; Bulotta, Alessandra A; Cangi, Maria Giulia MG; Khater, Abdelrahman A; Viganò, Maria Grazia MG; Mirabile, Aurora A; Pecciarini, Lorenza L; Ogliari, Francesca Rita FR; Arrigoni, Gianluigi G; Grassini, Greta G; Veronesi, Giulia G; Doglioni, Claudio C

Publication Date: 2021-04-22

Variant appearance in text: ALK: S1206Y

PubMed Link: 33922215

Variant Present in the following documents:

• Main text

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Future Perspectives in Detecting EGFR and ALK Gene Alterations in Liquid Biopsies of Patients with NSCLC.

International Journal Of Molecular Sciences

Ferreira, Daniela D; Miranda, Juliana J; Martins-Lopes, Paula P; Adega, Filomena F; Chaves, Raquel R

Publication Date: 2021-04-07

Variant appearance in text: ALK: S1206Y

PubMed Link: 33916986

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Current Knowledge about Mechanisms of Drug Resistance against ALK Inhibitors in Non-Small Cell Lung Cancer.

Cancers

Smolle, Elisabeth E; Taucher, Valentin V; Lindenmann, Joerg J; Jost, Philipp J PJ; Pichler, Martin M

Publication Date: 2021-02-09

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PubMed Link: 33572278

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Whole-exome mutational landscape of neuroendocrine carcinomas of the gallbladder.

Signal Transduction And Targeted Therapy

Liu, Fatao F; Li, Yongsheng Y; Ying, Dongjian D; Qiu, Shimei S; He, Yong Y; Li, Maolan M; Liu, Yun Y; Zhang, Yijian Y; Zhu, Qin Q; Hu, Yunping Y; Liu, Liguo L; Li, Guoqiang G; Pan, Weihua W; Jin, Wei W; Mu, Jiasheng J; Cao, Yang Y; Liu, Yingbin Y

Publication Date: 2021-02-10

Variant appearance in text: ALK: S1206Y

PubMed Link: 33563892

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• 41392_2020_Article_412.pdf

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