Publications:

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First case report of ensartinib in a patient with metastatic ALK rearranged lung cancer with ALK I1171N mutation: a case report.

World Journal Of Surgical Oncology

Yang, Shuang S; Feng, Weineng W; Deng, Yanming Y; Liang, Jianmiao J

Publication Date: 2023-03-02

Variant appearance in text: ALK: S1206R

PubMed Link: 36864442

Variant Present in the following documents:

• Main text
• 12957_2023_Article_2935.pdf

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Ensartinib in advanced ALK-positive non-small cell lung cancer: a multicenter, open-label, two-staged, phase 1 trial.

Journal Of Thoracic Disease

Ma, Yuxiang Y; Pan, Hui H; Liu, Yu Y; Zhang, Yang Y; Hong, Shaodong S; Huang, Jianjin J; Weng, Shanshan S; Yang, Yunpeng Y; Fang, Wenfeng W; Huang, Yan Y; Xiao, Shanshan S; Wang, Tao T; Ding, Lieming L; Cui, Lingling L; Zhang, Li L; Zhao, Hongyun H

Publication Date: 2022-12

Variant appearance in text: ALK: S1206R

PubMed Link: 36647478

Variant Present in the following documents:

• Main text
• jtd-14-12-4751.pdf

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Non-small-cell lung cancer: how to manage ALK-, ROS1- and NTRK-rearranged disease.

Drugs In Context

Marinelli, Daniele D; Siringo, Marco M; Metro, Giulio G; Ricciuti, Biagio B; Gelibter, Alain J AJ

Publication Date: 2022

Variant appearance in text: ALK: S1206R

PubMed Link: 36303600

Variant Present in the following documents:

• Main text
• dic-2022-3-1.pdf

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Anaplastic lymphoma kinase inhibitors and their effect on the kidney.

Clinical Kidney Journal

Bonilla, Marco M; Jhaveri, Kenar D KD; Izzedine, Hassan H

Publication Date: 2022-08

Variant appearance in text: ALK: S1206R

PubMed Link: 35892021

Variant Present in the following documents:

• Main text
• sfac062.pdf

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Metastasis manners and the underlying mechanisms of ALK and ROS1 rearrangement lung cancer and current possible therapeutic strategies.

Rsc Advances

Chang, Xing X; Liu, Zi Z; Man, Shuai S; Roys, Annie A; Li, Zengqiang Z; Zuo, Daiying D; Wu, Yingliang Y

Publication Date: 2019-06-04

Variant appearance in text: ALK: S1206R

PubMed Link: 35520562

Variant Present in the following documents:

• Main text
• RA-009-C9RA02258A.pdf

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Utility of the Ba/F3 cell system for exploring on-target mechanisms of resistance to targeted therapies for lung cancer.

Cancer Science

Koga, Takamasa T; Suda, Kenichi K; Mitsudomi, Tetsuya T

Publication Date: 2022-03

Variant appearance in text: ALK: S1206R

PubMed Link: 34997674

Variant Present in the following documents:

• CAS-113-815.pdf
• CAS-113-815-s001.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ALK: S1206R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

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Will the clinical development of 4th-generation "double mutant active" ALK TKIs (TPX-0131 and NVL-655) change the future treatment paradigm of ALK+ NSCLC?

Translational Oncology

Ou, Sai-Hong Ignatius SI; Nagasaka, Misako M; Brazel, Danielle D; Hou, Yujie Y; Zhu, Viola W VW

Publication Date: 2021-11

Variant appearance in text: ALK: S1206R

PubMed Link: 34365220

Variant Present in the following documents:

• Main text
• main.pdf

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[Whole-process Management of Treatment of Advanced ALK Positive Non-small Cell Lung Cancer: A Case Report].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Bai, Henan H; Han, Yu Y; Niu, Yi Y; Zhang, Minghui M

Publication Date: 2021-08-20

Variant appearance in text: ALK: S1206R

PubMed Link: 34344501

Variant Present in the following documents:

• Main text
• zgfazz-24-8-598.pdf

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TPX-0131, a Potent CNS-penetrant, Next-generation Inhibitor of Wild-type ALK and ALK-resistant Mutations.

Molecular Cancer Therapeutics

Murray, Brion W BW; Zhai, Dayong D; Deng, Wei W; Zhang, Xin X; Ung, Jane J; Nguyen, Vivian V; Zhang, Han H; Barrera, Maria M; Parra, Ana A; Cowell, Jessica J; Lee, Dong J DJ; Aloysius, Herve H; Rogers, Evan E

Publication Date: 2021-09

Variant appearance in text: ALK: S1206R

PubMed Link: 34158340

Variant Present in the following documents:

• Main text
• 1499.pdf

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An insight into lung cancer: a comprehensive review exploring ALK TKI and mechanisms of resistance.

Bosnian Journal Of Basic Medical Sciences

Patcas, Adela A; Chis, Ana Florica AF; Militaru, Claudia Florentina CF; Bordea, Ioana Roxana IR; Rajnoveanu, Ruxandra R; Coza, Ovidiu Florin OF; Hanna, Reem R; Tiberiu, Tamas T; Todea, Doina Adina DA

Publication Date: 2022-02-01

Variant appearance in text: ALK: S1206R

PubMed Link: 34082691

Variant Present in the following documents:

• Main text
• BJBMS-22-1.pdf

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The Emerging Therapeutic Landscape of ALK Inhibitors in Non-Small Cell Lung Cancer.

Pharmaceuticals (Basel, Switzerland)

Gristina, Valerio V; La Mantia, Maria M; Iacono, Federica F; Galvano, Antonio A; Russo, Antonio A; Bazan, Viviana V

Publication Date: 2020-12-18

Variant appearance in text: ALK: S1206R

PubMed Link: 33352844

Variant Present in the following documents:

• Main text
• pharmaceuticals-13-00474.pdf

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[Pharmacology and Clinical Evaluation of Ensartinib Hydrochloride Capsule].

Zhongguo Fei Ai Za Zhi = Chinese Journal Of Lung Cancer

Wang, Yang Y; Yuan, Xiaobin X; Xiong, Jiayan J; Hao, Zhidong Z; Peng, Xingzhe X; Chen, Wanlin W; Cui, Lingling L; Li, Hua H; Wang, Xiulan X; He, Xiangbo X; Yang, Min M; Liang, Congxin C; Ma, Yongbin Y; Ding, Lieming L; Mao, Li L

Publication Date: 2020-08-20

Variant appearance in text: ALK: S1206R

PubMed Link: 32838492

Variant Present in the following documents:

• Main text
• zgfazz-23-8-719.pdf

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Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association

Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H

Publication Date: 2020-07

Variant appearance in text: ALK: S1206R

PubMed Link: 32107691

Variant Present in the following documents:

• 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12

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New generation anaplastic lymphoma kinase inhibitors.

Translational Lung Cancer Research

Delmonte, Angelo A; Burgio, Marco Angelo MA; Verlicchi, Alberto A; Bronte, Giuseppe G; Cravero, Paola P; Ulivi, Paola P; Martinelli, Giovanni G; Crinò, Lucio L

Publication Date: 2019-11

Variant appearance in text: ALK: S1206R

PubMed Link: 31857951

Variant Present in the following documents:

• Main text

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Ensartinib (X-396) in ALK-Positive Non-Small Cell Lung Cancer: Results from a First-in-Human Phase I/II, Multicenter Study.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Horn, Leora L; Infante, Jeffrey R JR; Reckamp, Karen L KL; Blumenschein, George R GR; Leal, Ticiana A TA; Waqar, Saiama N SN; Gitlitz, Barbara J BJ; Sanborn, Rachel E RE; Whisenant, Jennifer G JG; Du, Liping L; Neal, Joel W JW; Gockerman, Jon P JP; Dukart, Gary G; Harrow, Kimberly K; Liang, Chris C; Gibbons, James J JJ; Holzhausen, Allison A; Lovly, Christine M CM; Wakelee, Heather A HA

Publication Date: 2018-06-15

Variant appearance in text: ALK: S1206R

PubMed Link: 29563138

Variant Present in the following documents:

• Main text

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Anaplastic lymphoma kinase: Role in cancer and therapy perspective.

Cancer Biology & Therapy

Zhao, Zhihong Z; Verma, Vivek V; Zhang, Mutian M

Publication Date: 2015

Variant appearance in text: ALK: S1206R

PubMed Link: 26529396

Variant Present in the following documents:

• Main text

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Treating patients with ALK-positive non-small cell lung cancer: latest evidence and management strategy.

Therapeutic Advances In Medical Oncology

Liao, Bin-Chi BC; Lin, Chia-Chi CC; Shih, Jin-Yuan JY; Yang, James Chih-Hsin JC

Publication Date: 2015-09

Variant appearance in text: ALK: S1206R

PubMed Link: 26327925

Variant Present in the following documents:

• Main text

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ALK and ROS1 as a joint target for the treatment of lung cancer: a review.

Translational Lung Cancer Research

Puig de la Bellacasa, Raimon R; Karachaliou, Niki N; Estrada-Tejedor, Roger R; Teixidó, Jordi J; Costa, Carlota C; Borrell, José I JI

Publication Date: 2013-04

Variant appearance in text: ALK: S1206R

PubMed Link: 25806218

Variant Present in the following documents:

• Main text

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ALK-rearrangements and testing methods in non-small cell lung cancer: a review.

Genes & Cancer

Shackelford, Rodney E RE; Vora, Moiz M; Mayhall, Kim K; Cotelingam, James J

Publication Date: 2014-04

Variant appearance in text: ALK: S1206R

PubMed Link: 24955213

Variant Present in the following documents:

• Main text
• ganc-05-001.pdf

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Clinical use of crizotinib for the treatment of non-small cell lung cancer.

Biologics : Targets & Therapy

Roberts, Patrick J PJ

Publication Date: 2013

Variant appearance in text: ALK: S1206R

PubMed Link: 23671386

Variant Present in the following documents:

• Main text
• btt-7-091.pdf

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Crizotinib-resistant mutants of EML4-ALK identified through an accelerated mutagenesis screen.

Chemical Biology & Drug Design

Zhang, Sen S; Wang, Frank F; Keats, Jeffrey J; Zhu, Xiaotian X; Ning, Yaoyu Y; Wardwell, Scott D SD; Moran, Lauren L; Mohemmad, Qurish K QK; Anjum, Rana R; Wang, Yihan Y; Narasimhan, Narayana I NI; Dalgarno, David D; Shakespeare, William C WC; Miret, Juan J JJ; Clackson, Tim T; Rivera, Victor M VM

Publication Date: 2011-12

Variant appearance in text: ALK: S1206R

PubMed Link: 22034911

Variant Present in the following documents:

• Main text
• cbdd0078-0999.pdf

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New strategies for treatment of ALK-rearranged non-small cell lung cancers.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Sasaki, Takaaki T; Jänne, Pasi A PA

Publication Date: 2011-12-01

Variant appearance in text: ALK: S1206R

PubMed Link: 22010214

Variant Present in the following documents:

• Main text

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