ALK c.3593T>C ;(p.L1198P)

Variant ID: 2-29443624-A-G

NM_004304.4(ALK):c.3593T>C;(p.L1198P)

This variant was identified in 14 publications

View GRCh38 version.




Publications:


Role of STK11 in ALK-positive non-small cell lung cancer.

Oncology Letters
Zhou, Wen W; Yan, Lu-Da LD; Yu, Zhi-Qiong ZQ; Li, Na N; Yang, Yong-Hua YH; Wang, Meng M; Chen, Yuan-Yuan YY; Mao, Meng-Xia MX; Peng, Xiao-Chun XC; Cai, Jun J
Publication Date: 2022-06

Variant appearance in text: ALK: L1198P
PubMed Link: 35527776
Variant Present in the following documents:
  • Main text
  • ol-23-06-13301.pdf
View BVdb publication page



Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers
Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD
Publication Date: 2021-11-29

Variant appearance in text: ALK: L1198P
PubMed Link: 34885113
Variant Present in the following documents:
  • Main text
  • cancers-13-06003.pdf
View BVdb publication page



Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers
Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD
Publication Date: 2021-11-29

Variant appearance in text: ALK: L1198P
PubMed Link: 34885113
Variant Present in the following documents:
  • Main text
  • cancers-13-06003.pdf
View BVdb publication page



The Resistance Mechanisms and Treatment Strategies for ALK-Rearranged Non-Small Cell Lung Cancer.

Frontiers In Oncology
Pan, Yue Y; Deng, Chao C; Qiu, Zhenhua Z; Cao, Chenghui C; Wu, Fang F
Publication Date: 2021

Variant appearance in text: ALK: L1198P
PubMed Link: 34660278
Variant Present in the following documents:
  • Main text
View BVdb publication page



Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology
Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C
Publication Date: 2021

Variant appearance in text: ALK: L1198P
PubMed Link: 34630336
Variant Present in the following documents:
  • Table_1.xlsx, sheet 2
View BVdb publication page



Identification of targeted therapy options for gastric adenocarcinoma by comprehensive analysis of genomic data.

Gastric Cancer : Official Journal Of The International Gastric Cancer Association And The Japanese Gastric Cancer Association
Hescheler, Daniel A DA; Plum, Patrick S PS; Zander, Thomas T; Quaas, Alexander A; Korenkov, Michael M; Gassa, Asmae A; Michel, Maximilian M; Bruns, Christiane J CJ; Alakus, Hakan H
Publication Date: 2020-07

Variant appearance in text: ALK: L1198P
PubMed Link: 32107691
Variant Present in the following documents:
  • 10120_2020_1045_MOESM1_ESM.xlsx, sheet 12
View BVdb publication page



Role of liquid biopsy in oncogene-addicted non-small cell lung cancer.

Translational Lung Cancer Research
Canale, Matteo M; Pasini, Luigi L; Bronte, Giuseppe G; Delmonte, Angelo A; Cravero, Paola P; Crinò, Lucio L; Ulivi, Paola P
Publication Date: 2019-11

Variant appearance in text: ALK: L1198P
PubMed Link: 31857950
Variant Present in the following documents:
  • Main text
View BVdb publication page



Liquid Biopsy for the Detection of Resistance Mechanisms in NSCLC: Comparison of Different Blood Biomarkers.

Journal Of Clinical Medicine
Pasini, Luigi L; Ulivi, Paola P
Publication Date: 2019-07-09

Variant appearance in text: ALK: L1198P
PubMed Link: 31323990
Variant Present in the following documents:
  • Main text
  • jcm-08-00998.pdf
View BVdb publication page



Structure and energy based quantitative missense variant effect analysis provides insights into drug resistance mechanisms of anaplastic lymphoma kinase mutations.

Scientific Reports
Li, Jianzong J; Huang, Yue Y; Wu, Miaomiao M; Wu, Chuanfang C; Li, Xin X; Bao, Jinku J
Publication Date: 2018-07-13

Variant appearance in text: ALK: L1198P
PubMed Link: 30006516
Variant Present in the following documents:
  • Main text
  • 41598_2018_28752_MOESM5_ESM.xlsx, sheet 1
  • 41598_2018_28752_MOESM3_ESM.xlsx, sheet 1
  • 41598_2018_28752_MOESM7_ESM.xlsx, sheet 1
  • 41598_2018_Article_28752.pdf
View BVdb publication page



The function and therapeutic targeting of anaplastic lymphoma kinase (ALK) in non-small cell lung cancer (NSCLC).

Molecular Cancer
Golding, Brandon B; Luu, Anita A; Jones, Robert R; Viloria-Petit, Alicia M AM
Publication Date: 2018-02-19

Variant appearance in text: ALK: L1198P
PubMed Link: 29455675
Variant Present in the following documents:
  • Main text
  • 12943_2018_Article_810.pdf
View BVdb publication page



Personalised medicine for nonsmall cell lung cancer.

European Respiratory Review : An Official Journal Of The European Respiratory Society
Mascaux, Céline C; Tomasini, Pascale P; Greillier, Laurent L; Barlesi, Fabrice F
Publication Date: 2017-12-31

Variant appearance in text: ALK: L1198P
PubMed Link: 29141962
Variant Present in the following documents:
  • Main text
  • ERR-0066-2017.pdf
View BVdb publication page



ALK: a tyrosine kinase target for cancer therapy.

Cold Spring Harbor Molecular Case Studies
Holla, Vijaykumar R VR; Elamin, Yasir Y YY; Bailey, Ann Marie AM; Johnson, Amber M AM; Litzenburger, Beate C BC; Khotskaya, Yekaterina B YB; Sanchez, Nora S NS; Zeng, Jia J; Shufean, Md Abu MA; Shaw, Kenna R KR; Mendelsohn, John J; Mills, Gordon B GB; Meric-Bernstam, Funda F; Simon, George R GR
Publication Date: 2017-01

Variant appearance in text: ALK: L1198P
PubMed Link: 28050598
Variant Present in the following documents:
  • Main text
  • HollaMCS001115.pdf
View BVdb publication page



Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

Journal Of Thoracic Oncology : Official Publication Of The International Association For The Study Of Lung Cancer
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Publication Date: 2013-07

Variant appearance in text: ALK: L1198P
PubMed Link: 23552377
Variant Present in the following documents:
  • Main text
View BVdb publication page



Molecular testing guideline for selection of lung cancer patients for EGFR and ALK tyrosine kinase inhibitors: guideline from the College of American Pathologists, International Association for the Study of Lung Cancer, and Association for Molecular Pathology.

Archives Of Pathology & Laboratory Medicine
Lindeman, Neal I NI; Cagle, Philip T PT; Beasley, Mary Beth MB; Chitale, Dhananjay Arun DA; Dacic, Sanja S; Giaccone, Giuseppe G; Jenkins, Robert Brian RB; Kwiatkowski, David J DJ; Saldivar, Juan-Sebastian JS; Squire, Jeremy J; Thunnissen, Erik E; Ladanyi, Marc M
Publication Date: 2013-06

Variant appearance in text: ALK: L1198P
PubMed Link: 23551194
Variant Present in the following documents:
  • Main text
View BVdb publication page



ALK mutations conferring differential resistance to structurally diverse ALK inhibitors.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research
Heuckmann, Johannes M JM; Hölzel, Michael M; Sos, Martin L ML; Heynck, Stefanie S; Balke-Want, Hyatt H; Koker, Mirjam M; Peifer, Martin M; Weiss, Jonathan J; Lovly, Christine M CM; Grütter, Christian C; Rauh, Daniel D; Pao, William W; Thomas, Roman K RK
Publication Date: 2011-12-01

Variant appearance in text: ALK: L1198P
PubMed Link: 21948233
Variant Present in the following documents:
  • Main text
View BVdb publication page