ALK c.3577T>C ;(p.F1193L)

Variant ID: 2-29443640-A-G

NM_004304.4(ALK):c.3577T>C;(p.F1193L)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Comprehensive germline and somatic genomic profiles of Chinese patients with biliary tract cancer.

Frontiers In Oncology
Yu, Haipeng H; Xu, Yan Y; Gao, Wei W; Li, Mei M; He, Ji'an J; Deng, Xiaoqian X; Xing, Wenge W
Publication Date: 2022

Variant appearance in text: ALK: F1193L
PubMed Link: 36072793
Variant Present in the following documents:
  • Table_3.xlsx, sheet 1
View BVdb publication page



Pancreatic Cancer-Related Mutational Burden Is Not Increased in a Patient Cohort With Clinically Severe Chronic Pancreatitis.

Clinical And Translational Gastroenterology
Cowan, Robert W RW; Pratt, Erica D ED; Kang, Jin Muk JM; Zhao, Jun J; Wilhelm, Joshua J JJ; Abdulla, Muhamad M; Qiao, Edmund M EM; Brennan, Luke P LP; Ulintz, Peter J PJ; Bellin, Melena D MD; Rhim, Andrew D AD
Publication Date: 2021-11-18

Variant appearance in text: ALK: 3577T>C; Phe1193Leu
PubMed Link: 34797250
Variant Present in the following documents:
  • ct9-12-e00431-s005.xlsx, sheet 1
  • ct9-12-e00431-s006.xlsx, sheet 1
View BVdb publication page



NPM/ALK mutants resistant to ASP3026 display variable sensitivity to alternative ALK inhibitors but succumb to the novel compound PF-06463922.

Oncotarget
Mologni, Luca L; Ceccon, Monica M; Pirola, Alessandra A; Chiriano, Gianpaolo G; Piazza, Rocco R; Scapozza, Leonardo L; Gambacorti-Passerini, Carlo C
Publication Date: 2015-03-20

Variant appearance in text: ALK: F1193L
PubMed Link: 25749034
Variant Present in the following documents:
  • oncotarget-06-5720-s001.pdf
View BVdb publication page