ALK c.3553G>C ;(p.V1185L)

Variant ID: 2-29443664-C-G

NM_004304.4(ALK):c.3553G>C;(p.V1185L)

This variant was identified in 7 publications

View GRCh38 version.




Publications:


Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers
Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD
Publication Date: 2021-11-29

Variant appearance in text: ALK: V1185L
PubMed Link: 34885113
Variant Present in the following documents:
  • Main text
  • cancers-13-06003.pdf
View BVdb publication page



Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers
Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD
Publication Date: 2021-11-29

Variant appearance in text: ALK: V1185L
PubMed Link: 34885113
Variant Present in the following documents:
  • Main text
  • cancers-13-06003.pdf
View BVdb publication page



Genomic profiling reveals heterogeneous populations of ductal carcinoma in situ of the breast.

Communications Biology
Nagasawa, Satoi S; Kuze, Yuta Y; Maeda, Ichiro I; Kojima, Yasuyuki Y; Motoyoshi, Ai A; Onishi, Tatsuya T; Iwatani, Tsuguo T; Yokoe, Takamichi T; Koike, Junki J; Chosokabe, Motohiro M; Kubota, Manabu M; Seino, Hibiki H; Suzuki, Ayako A; Seki, Masahide M; Tsuchihara, Katsuya K; Inoue, Eisuke E; Tsugawa, Koichiro K; Ohta, Tomohiko T; Suzuki, Yutaka Y
Publication Date: 2021-04-01

Variant appearance in text: ALK: V1185L
PubMed Link: 33795819
Variant Present in the following documents:
  • 42003_2021_1959_MOESM10_ESM.xlsx, sheet 1
View BVdb publication page



Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports
Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA
Publication Date: 2020-09-21

Variant appearance in text: ALK: V1185L
PubMed Link: 32958805
Variant Present in the following documents:
  • 41598_2020_72404_MOESM2_ESM.xlsx, sheet 3
View BVdb publication page



Improvement in predicting drug sensitivity changes associated with protein mutations using a molecular dynamics based alchemical mutation method.

Scientific Reports
Ono, Fumie F; Chiba, Shuntaro S; Isaka, Yuta Y; Matsumoto, Shigeyuki S; Ma, Biao B; Katayama, Ryohei R; Araki, Mitsugu M; Okuno, Yasushi Y
Publication Date: 2020-02-07

Variant appearance in text: ALK: V1185L
PubMed Link: 32034220
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_58877.pdf
View BVdb publication page



Prediction of ALK mutations mediating ALK-TKIs resistance and drug re-purposing to overcome the resistance.

Ebiomedicine
Okada, Koutaroh K; Araki, Mitsugu M; Sakashita, Takuya T; Ma, Biao B; Kanada, Ryo R; Yanagitani, Noriko N; Horiike, Atsushi A; Koike, Sumie S; Oh-Hara, Tomoko T; Watanabe, Kana K; Tamai, Keiichi K; Maemondo, Makoto M; Nishio, Makoto M; Ishikawa, Takeshi T; Okuno, Yasushi Y; Fujita, Naoya N; Katayama, Ryohei R
Publication Date: 2019-03

Variant appearance in text: ALK: V1185L
PubMed Link: 30662002
Variant Present in the following documents:
  • Main text
  • main.pdf
  • mmc1.pdf
View BVdb publication page



Integrating in silico prediction methods, molecular docking, and molecular dynamics simulation to predict the impact of ALK missense mutations in structural perspective.

Biomed Research International
Doss, C George Priya CG; Chakraborty, Chiranjib C; Chen, Luonan L; Zhu, Hailong H
Publication Date: 2014

Variant appearance in text: ALK: V1185L
PubMed Link: 25054154
Variant Present in the following documents:
View BVdb publication page



Integrated analysis of germline and somatic variants in ovarian cancer.

Nature Communications
Kanchi, Krishna L KL; Johnson, Kimberly J KJ; Lu, Charles C; McLellan, Michael D MD; Leiserson, Mark D M MD; Wendl, Michael C MC; Zhang, Qunyuan Q; Koboldt, Daniel C DC; Xie, Mingchao M; Kandoth, Cyriac C; McMichael, Joshua F JF; Wyczalkowski, Matthew A MA; Larson, David E DE; Schmidt, Heather K HK; Miller, Christopher A CA; Fulton, Robert S RS; Spellman, Paul T PT; Mardis, Elaine R ER; Druley, Todd E TE; Graubert, Timothy A TA; Goodfellow, Paul J PJ; Raphael, Benjamin J BJ; Wilson, Richard K RK; Ding, Li L
Publication Date: 2014

Variant appearance in text: ALK: V1185L
PubMed Link: 24448499
Variant Present in the following documents:
  • NIHMS551112-supplement-9.xlsx, sheet 1
View BVdb publication page