Publications:

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Computational studies of anaplastic lymphoma kinase mutations reveal common mechanisms of oncogenic activation.

Proceedings Of The National Academy Of Sciences Of The United States Of America

Patil, Keshav K; Jordan, Earl Joseph EJ; Park, Jin H JH; Suresh, Krishna K; Smith, Courtney M CM; Lemmon, Abigail A AA; Mossé, Yaël P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R

Publication Date: 2021-03-09

Variant appearance in text: ALK: I1183T

PubMed Link: 33674381

Variant Present in the following documents:

• Main text
• pnas.202019132.pdf

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Identification of pathogenic missense mutations using protein stability predictors.

Scientific Reports

Gerasimavicius, Lukas L; Liu, Xin X; Marsh, Joseph A JA

Publication Date: 2020-09-21

Variant appearance in text: ALK: I1183T

PubMed Link: 32958805

Variant Present in the following documents:

• 41598_2020_72404_MOESM2_ESM.xlsx, sheet 3

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Comprehensive routine diagnostic screening to identify predictive mutations, gene amplifications, and microsatellite instability in FFPE tumor material.

Bmc Cancer

Steeghs, Elisabeth M P EMP; Kroeze, Leonie I LI; Tops, Bastiaan B J BBJ; van Kempen, Leon C LC; Ter Elst, Arja A; Kastner-van Raaij, Annemiek W M AWM; Hendriks-Cornelissen, Sandra J B SJB; Hermsen, Mandy J W MJW; Jansen, Erik A M EAM; Nederlof, Petra M PM; Schuuring, Ed E; Ligtenberg, Marjolijn J L MJL; Eijkelenboom, Astrid A

Publication Date: 2020-04-07

Variant appearance in text: ALK: 3548T>C; Ile1183Thr

PubMed Link: 32264863

Variant Present in the following documents:

• 12885_2020_6785_MOESM2_ESM.xlsx, sheet 7

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Computational algorithms for in silico profiling of activating mutations in cancer.

Cellular And Molecular Life Sciences : Cmls

Jordan, E Joseph EJ; Patil, Keshav K; Suresh, Krishna K; Park, Jin H JH; Mosse, Yael P YP; Lemmon, Mark A MA; Radhakrishnan, Ravi R

Publication Date: 2019-07

Variant appearance in text: ALK: I1183T

PubMed Link: 30982079

Variant Present in the following documents:

• Main text

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Formalin fixation increases deamination mutation signature but should not lead to false positive mutations in clinical practice.

Plos One

Prentice, Leah M LM; Miller, Ruth R RR; Knaggs, Jeff J; Mazloomian, Alborz A; Aguirre Hernandez, Rosalia R; Franchini, Patrick P; Parsa, Kourosh K; Tessier-Cloutier, Basile B; Lapuk, Anna A; Huntsman, David D; Schaeffer, David F DF; Sheffield, Brandon S BS

Publication Date: 2018

Variant appearance in text: ALK: I1183T

PubMed Link: 29698444

Variant Present in the following documents:

• pone.0196434.s001.xlsx, sheet 1
• pone.0196434.s001.xlsx, sheet 2

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Genetic susceptibility to neuroblastoma: current knowledge and future directions.

Cell And Tissue Research

Ritenour, Laura E LE; Randall, Michael P MP; Bosse, Kristopher R KR; Diskin, Sharon J SJ

Publication Date: 2018-05

Variant appearance in text: ALK: I1183T

PubMed Link: 29589100

Variant Present in the following documents:

• Main text

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Retinoblastoma and Neuroblastoma Predisposition and Surveillance.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Kamihara, Junne J; Bourdeaut, Franck F; Foulkes, William D WD; Molenaar, Jan J JJ; Mossé, Yaël P YP; Nakagawara, Akira A; Parareda, Andreu A; Scollon, Sarah R SR; Schneider, Kami Wolfe KW; Skalet, Alison H AH; States, Lisa J LJ; Walsh, Michael F MF; Diller, Lisa R LR; Brodeur, Garrett M GM

Publication Date: 2017-07-01

Variant appearance in text: ALK: I1183T

PubMed Link: 28674118

Variant Present in the following documents:

• Main text

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Anaplastic Lymphoma Kinase as a Cancer Target in Pediatric Malignancies.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Mossé, Yael P YP

Publication Date: 2016-02-01

Variant appearance in text: ALK: I1183T

PubMed Link: 26503946

Variant Present in the following documents:

• Main text

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ALK mutations confer differential oncogenic activation and sensitivity to ALK inhibition therapy in neuroblastoma.

Cancer Cell

Bresler, Scott C SC; Weiser, Daniel A DA; Huwe, Peter J PJ; Park, Jin H JH; Krytska, Kateryna K; Ryles, Hannah H; Laudenslager, Marci M; Rappaport, Eric F EF; Wood, Andrew C AC; McGrady, Patrick W PW; Hogarty, Michael D MD; London, Wendy B WB; Radhakrishnan, Ravi R; Lemmon, Mark A MA; Mossé, Yaël P YP

Publication Date: 2014-11-10

Variant appearance in text: ALK: I1183T

PubMed Link: 25517749

Variant Present in the following documents:

• Main text

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