Publications:

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Sustained Improvement in the Management of Patients with Non-Small-Cell Lung Cancer (NSCLC) Harboring ALK Translocation: Where Are We Running?

Current Oncology (Toronto, Ont.)

Spitaleri, Gianluca G; Trillo Aliaga, Pamela P; Attili, Ilaria I; Del Signore, Ester E; Corvaja, Carla C; Corti, Chiara C; Crimini, Edoardo E; Passaro, Antonio A; de Marinis, Filippo F

Publication Date: 2023-05-16

Variant appearance in text: ALK: I1171N

PubMed Link: 37232842

Variant Present in the following documents:

• Main text
• curroncol-30-00384.pdf

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Clinical characteristics and targeted therapy of different gene fusions in non-small cell lung cancer: a narrative review.

Translational Lung Cancer Research

Chen, Jiayan J; Xu, Chunwei C; Lv, Jiawen J; Lu, Wanjun W; Zhang, Yixue Y; Wang, Dong D; Song, Yong Y

Publication Date: 2023-04-28

Variant appearance in text: ALK: I1171N

PubMed Link: 37197619

Variant Present in the following documents:

• Main text
• tlcr-12-04-895.pdf

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Circulating tumor DNA reveals mechanisms of lorlatinib resistance in patients with relapsed/refractory ALK-driven neuroblastoma.

Nature Communications

Berko, Esther R ER; Witek, Gabriela M GM; Matkar, Smita S; Petrova, Zaritza O ZO; Wu, Megan A MA; Smith, Courtney M CM; Daniels, Alex A; Kalna, Joshua J; Kennedy, Annie A; Gostuski, Ivan I; Casey, Colleen C; Krytska, Kateryna K; Gerelus, Mark M; Pavlick, Dean D; Ghazarian, Susan S; Park, Julie R JR; Marachelian, Araz A; Maris, John M JM; Goldsmith, Kelly C KC; Radhakrishnan, Ravi R; Lemmon, Mark A MA; Mossé, Yaël P YP

Publication Date: 2023-05-05

Variant appearance in text: ALK: I1171N

PubMed Link: 37147298

Variant Present in the following documents:

• Main text
• 41467_2023_Article_38195.pdf

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Reversible transitions between noradrenergic and mesenchymal tumor identities define cell plasticity in neuroblastoma.

Nature Communications

Thirant, Cécile C; Peltier, Agathe A; Durand, Simon S; Kramdi, Amira A; Louis-Brennetot, Caroline C; Pierre-Eugène, Cécile C; Gautier, Margot M; Costa, Ana A; Grelier, Amandine A; Zaïdi, Sakina S; Gruel, Nadège N; Jimenez, Irène I; Lapouble, Eve E; Pierron, Gaëlle G; Sitbon, Déborah D; Brisse, Hervé J HJ; Gauthier, Arnaud A; Fréneaux, Paul P; Grossetête, Sandrine S; Baudrin, Laura G LG; Raynal, Virginie V; Baulande, Sylvain S; Bellini, Angela A; Bhalshankar, Jaydutt J; Carcaboso, Angel M AM; Geoerger, Birgit B; Rohrer, Hermann H; Surdez, Didier D; Boeva, Valentina V; Schleiermacher, Gudrun G; Delattre, Olivier O; Janoueix-Lerosey, Isabelle I

Publication Date: 2023-05-04

Variant appearance in text: ALK: I1171N

PubMed Link: 37142597

Variant Present in the following documents:

• 41467_2023_38239_MOESM1_ESM.pdf

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Strategies to overcome resistance to ALK inhibitors in non-small cell lung cancer: a narrative review.

Translational Lung Cancer Research

Desai, Aakash A; Lovly, Christine M CM

Publication Date: 2023-03-31

Variant appearance in text: ALK: I1171N

PubMed Link: 37057106

Variant Present in the following documents:

• Main text
• tlcr-12-03-615.pdf

View BVdb publication page

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Acquired ALK G1202R-, ALK I1171N-, or EML4-ALK-mediated resistance to ensartinib in lung adenocarcinoma but responded to lorlatinib: A case report.

Frontiers In Oncology

Ye, Zhifeng Z; Guo, Junhua J

Publication Date: 2023

Variant appearance in text: ALK: I1171N

PubMed Link: 37007089

Variant Present in the following documents:

• Main text
• fonc-13-1082115.pdf

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First case report of ensartinib in a patient with metastatic ALK rearranged lung cancer with ALK I1171N mutation: a case report.

World Journal Of Surgical Oncology

Yang, Shuang S; Feng, Weineng W; Deng, Yanming Y; Liang, Jianmiao J

Publication Date: 2023-03-02

Variant appearance in text: ALK: I1171N

PubMed Link: 36864442

Variant Present in the following documents:

• Main text
• 12957_2023_Article_2935.pdf

View BVdb publication page

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Alectinib as first-line treatment for advanced ALK-positive non-small cell lung cancer in the real-world setting: preliminary analysis in a Chinese cohort.

Translational Lung Cancer Research

Zou, Zihua Z; Gu, Yangchun Y; Liang, Li L; Hao, Xuezhi X; Fan, Chengjuan C; Xin, Tao T; Zhao, Songchen S; Liu, Ziling Z; Guo, Ye Y; Ma, Kewei K; Li, Haojing H; Zhang, Cuiying C; Shan, Li L; Zhang, Yan Y; Dong, Guilan G; Peng, Yumei Y; Shen, Fangfang F; Song, Xia X; Christopoulos, Petros P; van der Wekken, Anthonie J AJ; Okuda, Katsuhiro K; Ekman, Simon S; Xing, Puyuan P; Li, Junling J

Publication Date: 2022-12

Variant appearance in text: ALK: I1171N

PubMed Link: 36636411

Variant Present in the following documents:

• tlcr-11-12-2495.pdf

View BVdb publication page

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Combination Therapies Targeting Alk-Aberrant Neuroblastoma in Preclinical Models.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Tucker, Elizabeth R ER; Jiménez, Irene I; Chen, Lindi L; Bellini, Angela A; Gorrini, Chiara C; Calton, Elizabeth E; Gao, Qiong Q; Che, Harvey H; Poon, Evon E; Jamin, Yann Y; Martins Da Costa, Barbara B; Barker, Karen K; Shrestha, Sumana S; Hutchinson, J Ciaran JC; Dhariwal, Simran S; Goodman, Angharad A; Del Nery, Elaine E; Gestraud, Pierre P; Bhalshankar, Jaydutt J; Iddir, Yasmine Y; Saberi-Ansari, Elnaz E; Saint-Charles, Alexandra A; Geoerger, Birgit B; Marques Da Costa, Maria Eugenia ME; Pierre-Eugene, Cecile C; Janoueix-Lerosey, Isabelle I; Decaudin, Didier D; Némati, Fariba F; Carcaboso, Angel M AM; Surdez, Didier D; Delattre, Olivier O; George, Sally L SL; Chesler, Louis L; Tweddle, Deborah A DA; Schleiermacher, Gudrun G

Publication Date: 2023-01-05

Variant appearance in text: ALK: I1171N

PubMed Link: 36602782

Variant Present in the following documents:

• Main text

View BVdb publication page

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Non-Small Cell Lung Cancer Targeted Therapy: Drugs and Mechanisms of Drug Resistance.

International Journal Of Molecular Sciences

Wu, Jiajia J; Lin, Zhenghong Z

Publication Date: 2022-12-01

Variant appearance in text: ALK: I1171N

PubMed Link: 36499382

Variant Present in the following documents:

• Main text
• ijms-23-15056.pdf

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Landscape of potentially targetable receptor tyrosine kinase fusions in diverse cancers by DNA-based profiling.

Npj Precision Oncology

Wang, Tiantian T; Wei, Li L; Lu, Qiang Q; Shao, Yanmei Y; You, Shuqing S; Yin, Jiani C JC; Wang, Sha S; Shao, Yang Y; Chen, Zhanhong Z; Wang, Zhe Z

Publication Date: 2022-11-11

Variant appearance in text: ALK: I1171N

PubMed Link: 36369474

Variant Present in the following documents:

• 41698_2022_Article_325.pdf

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Secondary mutant ALK-I1171s in pituitary metastases from a patient with ALK fusion-positive advanced lung adenocarcinoma: A case report and literature review.

Frontiers In Oncology

Han, Dan D; Zhao, Kewei K; Yang, Qin Q; Zhang, Liling L; Fei, Shihong S

Publication Date: 2022

Variant appearance in text: ALK: I1171N

PubMed Link: 36324562

Variant Present in the following documents:

• Main text
• fonc-12-1016320.pdf

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Therapeutic Advances of Rare ALK Fusions in Non-Small Cell Lung Cancer.

Current Oncology (Toronto, Ont.)

Xiang, Yan Y; Zhang, Shiyu S; Fang, Xiaoxu X; Jiang, Yingying Y; Fang, Tingwen T; Liu, Jinwen J; Lu, Kaihua K

Publication Date: 2022-10-16

Variant appearance in text: ALK: I1171N

PubMed Link: 36290895

Variant Present in the following documents:

• curroncol-29-00618.pdf

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Molecular targeted therapy for anticancer treatment.

Experimental & Molecular Medicine

Min, Hye-Young HY; Lee, Ho-Young HY

Publication Date: 2022-10

Variant appearance in text: ALK: I1171N

PubMed Link: 36224343

Variant Present in the following documents:

• Main text
• 12276_2022_Article_864.pdf

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Pan-HER inhibitors overcome lorlatinib resistance caused by NRG1/HER3 activation in ALK-rearranged lung cancer.

Cancer Science

Taniguchi, Hirokazu H; Akagi, Kazumasa K; Dotsu, Yosuke Y; Yamada, Tadaaki T; Ono, Sawana S; Imamura, Erika E; Gyotoku, Hiroshi H; Takemoto, Shinnosuke S; Yamaguchi, Hiroyuki H; Sen, Triparna T; Yano, Seiji S; Mukae, Hiroshi H

Publication Date: 2022-09-10

Variant appearance in text: ALK: I1171N

PubMed Link: 36086904

Variant Present in the following documents:

• Main text
• CAS-114-164.pdf

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Mechanistic Insights into the Mechanism of Inhibitor Selectivity toward the Dark Kinase STK17B against Its High Homology STK17A.

Molecules (Basel, Switzerland)

Liu, Chang C; Zhang, Yichi Y; Zhang, Yuqing Y; Liu, Zonghan Z; Mao, Feifei F; Chai, Zongtao Z

Publication Date: 2022-07-21

Variant appearance in text: ALK: I1171N

PubMed Link: 35889528

Variant Present in the following documents:

• molecules-27-04655.pdf

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Metastatic pulmonary carcinoids with EML4-ALK fusion response to ALK inhibitors: two case reports and review of literature.

Translational Lung Cancer Research

Lei, Xi X; Zhu, Shuai S; Ren, Dian D; Ren, Fan F; Li, Tong T; Zhou, Ning N; Li, Shuo S; Shi, Tao T; Zu, Lingling L; Song, Zuoqing Z; Chalubinska-Fendler, Justyna J; Denis, Marc G MG; Bernicker, Eric H EH; Thomas de Montpréville, Vincent V; Jiang, Richeng R; Xu, Song S

Publication Date: 2022-06

Variant appearance in text: ALK: I1171N

PubMed Link: 35832448

Variant Present in the following documents:

• Main text
• tlcr-11-06-1176.pdf

View BVdb publication page

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AACR Project GENIE: 100,000 Cases and Beyond.

Cancer Discovery

Pugh, Trevor J TJ; Bell, Jonathan L JL; Bruce, Jeff P JP; Doherty, Gary J GJ; Galvin, Matthew M; Green, Michelle F MF; Hunter-Zinck, Haley H; Kumari, Priti P; Lenoue-Newton, Michele L ML; Li, Marilyn M MM; Lindsay, James J; Mazor, Tali T; Ovalle, Andrea A; Sammut, Stephen-John SJ; Schultz, Nikolaus N; Yu, Thomas V TV; Sweeney, Shawn M SM; Bernard, Brady B; ,

Publication Date: 2022-09-02

Variant appearance in text: ALK: I1171N

PubMed Link: 35819403

Variant Present in the following documents:

• cd-21-1547_supplementary_table_1_suppst1.xlsx, sheet 1

View BVdb publication page

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Genomic Alterations Identification and Resistance Mechanisms Exploration of NSCLC With Central Nervous System Metastases Using Liquid Biopsy of Cerebrospinal Fluid: A Real-World Study.

Frontiers In Oncology

Shen, Fangfang F; Liang, Naixin N; Fan, Zaiwen Z; Zhao, Min M; Kang, Jing J; Wang, Xifang X; Hu, Qun Q; Mu, Yongping Y; Wang, Kai K; Yuan, Mingming M; Chen, Rongrong R; Guo, Wei W; Dong, Guilan G; Zhao, Jun J; Bai, Jun J

Publication Date: 2022

Variant appearance in text: ALK: 3512T>A; I1171N

PubMed Link: 35814426

Variant Present in the following documents:

• DataSheet_1.xlsx, sheet 2

View BVdb publication page

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The Impact of Comprehensive Genomic Profiling (CGP) on the Decision-Making Process in the Treatment of ALK-Rearranged Advanced Non-Small Cell Lung Cancer (aNSCLC) After Failure of 2nd/3rd-Generation ALK Tyrosine Kinase Inhibitors (TKIs).

Frontiers In Oncology

Raphael, Ari A; Onn, Amir A; Holtzman, Liran L; Dudnik, Julia J; Urban, Damien D; Kian, Waleed W; Cohen, Aharon Y AY; Moskovitz, Mor M; Zer, Alona A; Bar, Jair J; Rabinovich, Natalie Maimon NM; Grynberg, Shirly S; Oedegaard, Cecilie C; Agbarya, Abed A; Peled, Nir N; Shochat, Tzippy T; Dudnik, Elizabeth E

Publication Date: 2022

Variant appearance in text: ALK: I1171N

PubMed Link: 35646707

Variant Present in the following documents:

• Table_2.xlsx, sheet 1

View BVdb publication page

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Lorlatinib Versus Pemetrexed-Based Chemotherapy in Patients With ALK-rearranged NSCLC Previously Treated With Alectinib.

Jto Clinical And Research Reports

Takeyasu, Yuki Y; Yoshida, Tatsuya T; Masuda, Ken K; Matsumoto, Yuji Y; Shinno, Yuki Y; Okuma, Yusuke Y; Goto, Yasushi Y; Horinouchi, Hidehito H; Yamamoto, Noboru N; Ohe, Yuichiro Y

Publication Date: 2022-05

Variant appearance in text: ALK: I1171N

PubMed Link: 35498380

Variant Present in the following documents:

• Main text
• main.pdf

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Clinically actionable cancer somatic variants (CACSV): a tumor interpreted dataset for analytical workflows.

Bmc Medical Genomics

Sobahy, Turki M TM; Tashkandi, Ghassan G; Bahussain, Donya D; Al-Harbi, Raneem R

Publication Date: 2022-04-25

Variant appearance in text: ALK: 3512T>A

PubMed Link: 35468810

Variant Present in the following documents:

• 12920_2022_1235_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Morphologic-Molecular Transformation of Oncogene Addicted Non-Small Cell Lung Cancer.

International Journal Of Molecular Sciences

Calabrese, Fiorella F; Pezzuto, Federica F; Lunardi, Francesca F; Fortarezza, Francesco F; Tzorakoleftheraki, Sofia-Eleni SE; Resi, Maria Vittoria MV; Tiné, Mariaenrica M; Pasello, Giulia G; Hofman, Paul P

Publication Date: 2022-04-09

Variant appearance in text: ALK: I1171N

PubMed Link: 35456982

Variant Present in the following documents:

• Main text
• ijms-23-04164.pdf

View BVdb publication page

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Activity of ALK Inhibitors in Renal Cancer with ALK Alterations: A Systematic Review.

International Journal Of Molecular Sciences

Iannantuono, Giovanni Maria GM; Riondino, Silvia S; Sganga, Stefano S; Roselli, Mario M; Torino, Francesco F

Publication Date: 2022-04-03

Variant appearance in text: ALK: 3512T>A

PubMed Link: 35409355

Variant Present in the following documents:

• Main text
• ijms-23-03995.pdf

View BVdb publication page

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Regulatory spine RS3 residue of protein kinases: a lipophilic bystander or a decisive element in the small-molecule kinase inhibitor binding?

Biochemical Society Transactions

Shevchenko, Ekaterina E; Pantsar, Tatu T

Publication Date: 2022-02-28

Variant appearance in text: ALK: I1171N

PubMed Link: 35226061

Variant Present in the following documents:

• Main text
• BST-50-633.pdf

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: ALK: Ile1171Asn

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

View BVdb publication page

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Holistic View of ALK TKI Resistance in ALK-Positive Anaplastic Large Cell Lymphoma.

Frontiers In Oncology

Wang, Yuan Y; He, Jing J; Xu, Manyu M; Xue, Qingfeng Q; Zhu, Cindy C; Liu, Juan J; Zhang, Yaping Y; Shi, Wenyu W

Publication Date: 2022

Variant appearance in text: ALK: I1171N

PubMed Link: 35211406

Variant Present in the following documents:

• Main text
• fonc-12-815654.pdf

View BVdb publication page

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ALK-rearranged lung adenocarcinoma resistant to alectinib with cauliflower gingival metastasis responds to brigatinib.

Thoracic Cancer

Song, Lianxi L; Zeng, Liang L; Zhang, Yongchang Y

Publication Date: 2022-04

Variant appearance in text: ALK: I1171N

PubMed Link: 35150066

Variant Present in the following documents:

• TCA-13-1095.pdf

View BVdb publication page

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Prospective analysis of liquid biopsies of advanced non-small cell lung cancer patients after progression to targeted therapies using GeneReader NGS platform.

Translational Cancer Research

Mayo de Las Casas, Clara C; Garzón-Ibañez, Mónica M; Jordana-Ariza, Núria N; Viteri-Ramírez, Santiago S; Moya-Horno, Irene I; Karachaliou, Niki N; Yeste, Zaira Z; Campos, Raquel R; Villatoro, Sergi S; Balada-Bel, Ariadna A; García-Peláez, Beatriz B; Reguart, Noemí N; Teixidó, Cristina C; Jantús, Eloisa E; Calabuig, Silvia S; Aguado, Cristina C; Giménez-Capitán, Ana A; Román-Lladó, Ruth R; Pérez-Rosado, Ana A; Catalán, Maria José MJ; Bertrán-Alamillo, Jordi J; García-Román, Silvia S; Rodriguez, Sonia S; Alonso, Lidia L; Aldeguer, Erika E; Martínez-Bueno, Alejandro A; González-Cao, Maria M; Aguilar Hernandez, Andrés A; Garcia-Mosquera, Juan J; de Los Llanos Gil, Maria M; Fernandez, Manuel M; Rosell, Rafael R; Molina-Vila, Miguel Ángel MÁ

Publication Date: 2019-01

Variant appearance in text: ALK: I1171N

PubMed Link: 35117060

Variant Present in the following documents:

• Main text

View BVdb publication page

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Current Insights on the Treatment of Anaplastic Lymphoma Kinase-Positive Metastatic Non-Small Cell Lung Cancer: Focus on Brigatinib.

Clinical Pharmacology : Advances And Applications

Rijavec, Erika E; Biello, Federica F; Indini, Alice A; Grossi, Francesco F; Genova, Carlo C

Publication Date: 2022

Variant appearance in text: ALK: I1171N

PubMed Link: 35082536

Variant Present in the following documents:

• Main text
• cpaa-14-1.pdf

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Deciphering the Mechanism of Gilteritinib Overcoming Lorlatinib Resistance to the Double Mutant I1171N/F1174I in Anaplastic Lymphoma Kinase.

Frontiers In Cell And Developmental Biology

Liang, Shuai S; Wang, Qing Q; Qi, Xuesen X; Liu, Yudi Y; Li, Guozhen G; Lu, Shaoyong S; Mou, Linkai L; Chen, Xiangyu X

Publication Date: 2021

Variant appearance in text: ALK: I1171N

PubMed Link: 35004700

Variant Present in the following documents:

• Main text

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Therapeutic advances in non-small cell lung cancer: Focus on clinical development of targeted therapy and immunotherapy.

Medcomm

Cheng, Yuan Y; Zhang, Tao T; Xu, Qing Q

Publication Date: 2021-12

Variant appearance in text: ALK: I1171N

PubMed Link: 34977873

Variant Present in the following documents:

• Main text
• MCO2-2-692.pdf

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A full-proteome, interaction-specific characterization of mutational hotspots across human cancers.

Genome Research

Chen, Siwei S; Liu, Yuan Y; Zhang, Yingying Y; Wierbowski, Shayne D SD; Lipkin, Steven M SM; Wei, Xiaomu X; Yu, Haiyuan H

Publication Date: 2022-01

Variant appearance in text: ALK: I1171N

PubMed Link: 34963661

Variant Present in the following documents:

• supp_gr.275437.121_Supplementary_Table_1.xlsx, sheet 3

View BVdb publication page

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Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers

Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD

Publication Date: 2021-11-29

Variant appearance in text: ALK: I1171N

PubMed Link: 34885113

Variant Present in the following documents:

• Main text

View BVdb publication page

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Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers

Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD

Publication Date: 2021-11-29

Variant appearance in text: ALK: I1171N

PubMed Link: 34885113

Variant Present in the following documents:

• Main text

View BVdb publication page

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Targeting Oncogenic Transcriptional Networks in Neuroblastoma: From N-Myc to Epigenetic Drugs.

International Journal Of Molecular Sciences

Ciaccio, Roberto R; De Rosa, Piergiuseppe P; Aloisi, Sara S; Viggiano, Marta M; Cimadom, Leonardo L; Zadran, Suleman Khan SK; Perini, Giovanni G; Milazzo, Giorgio G

Publication Date: 2021-11-28

Variant appearance in text: ALK: Ile1171Asn

PubMed Link: 34884690

Variant Present in the following documents:

• Main text

View BVdb publication page

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Targeting Oncogenic Transcriptional Networks in Neuroblastoma: From N-Myc to Epigenetic Drugs.

International Journal Of Molecular Sciences

Ciaccio, Roberto R; De Rosa, Piergiuseppe P; Aloisi, Sara S; Viggiano, Marta M; Cimadom, Leonardo L; Zadran, Suleman Khan SK; Perini, Giovanni G; Milazzo, Giorgio G

Publication Date: 2021-11-28

Variant appearance in text: ALK: Ile1171Asn

PubMed Link: 34884690

Variant Present in the following documents:

• Main text

View BVdb publication page

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Recurrent PTPRZ1-MET fusion and a high occurrence rate of MET exon 14 skipping in brain metastases.

Cancer Science

Chai, Rui-Chao RC; Liu, Xing X; Pang, Bo B; Liu, Yu-Qing YQ; Li, Jing-Jun JJ; Li, Yang-Fang YF; Zhao, Zheng Z; Du, Jiang J; Bao, Zhao Shi ZS; Jiang, Tao T

Publication Date: 2022-02

Variant appearance in text: ALK: I1171N

PubMed Link: 34812554

Variant Present in the following documents:

• Main text
• CAS-113-796.pdf

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Recurrent PTPRZ1-MET fusion and a high occurrence rate of MET exon 14 skipping in brain metastases.

Cancer Science

Chai, Rui-Chao RC; Liu, Xing X; Pang, Bo B; Liu, Yu-Qing YQ; Li, Jing-Jun JJ; Li, Yang-Fang YF; Zhao, Zheng Z; Du, Jiang J; Bao, Zhao Shi ZS; Jiang, Tao T

Publication Date: 2021-11-23

Variant appearance in text: ALK: I1171N

PubMed Link: 34812554

Variant Present in the following documents:

• Main text
• CAS-113-796.pdf

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Defining Pathological Activities of ALK in Neuroblastoma, a Neural Crest-Derived Cancer.

International Journal Of Molecular Sciences

Wulf, Anna M AM; Moreno, Marcela M MM; Paka, Chloé C; Rampasekova, Alexandra A; Liu, Karen J KJ

Publication Date: 2021-10-29

Variant appearance in text: ALK: I1171N

PubMed Link: 34769149

Variant Present in the following documents:

• Main text

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Two novel strategies to overcome the resistance to ALK tyrosine kinase inhibitor drugs: Macrocyclic inhibitors and proteolysis-targeting chimeras.

Medcomm

Song, Xiaoling X; Zhong, Hui H; Qu, Xiaojuan X; Yang, Linsong L; Jiang, Biao B

Publication Date: 2021-09

Variant appearance in text: ALK: I1171N

PubMed Link: 34766150

Variant Present in the following documents:

• Main text
• MCO2-2-341.pdf

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New Advances in Liquid Biopsy Technologies for Anaplastic Lymphoma Kinase (ALK)-Positive Cancer.

Cancers

Villa, Matteo M; Sharma, Geeta G GG; Manfroni, Chiara C; Cortinovis, Diego D; Mologni, Luca L

Publication Date: 2021-10-14

Variant appearance in text: ALK: I1171N

PubMed Link: 34680298

Variant Present in the following documents:

• Main text

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The Resistance Mechanisms and Treatment Strategies for ALK-Rearranged Non-Small Cell Lung Cancer.

Frontiers In Oncology

Pan, Yue Y; Deng, Chao C; Qiu, Zhenhua Z; Cao, Chenghui C; Wu, Fang F

Publication Date: 2021

Variant appearance in text: ALK: I1171N

PubMed Link: 34660278

Variant Present in the following documents:

• Main text
• fonc-11-713530.pdf

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ALK: I1171N

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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A Novel Sequentially Evolved EML4-ALK Variant 3 G1202R/S1206Y Double Mutation In Cis Confers Resistance to Lorlatinib: A Brief Report and Literature Review.

Jto Clinical And Research Reports

Zhu, Viola W VW; Nagasaka, Misako M; Madison, Russell R; Schrock, Alexa B AB; Cui, Jean J; Ou, Sai-Hong Ignatius SI

Publication Date: 2021-01

Variant appearance in text: ALK: I1171N

PubMed Link: 34589977

Variant Present in the following documents:

• Main text

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Therapeutic Targeting of the Anaplastic Lymphoma Kinase (ALK) in Neuroblastoma-A Comprehensive Update.

Pharmaceutics

Brenner, Annette K AK; Gunnes, Maria W MW

Publication Date: 2021-09-08

Variant appearance in text: ALK: I1171N

PubMed Link: 34575503

Variant Present in the following documents:

• Main text
• pharmaceutics-13-01427.pdf

View BVdb publication page

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