Publications:

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Understanding and targeting resistance mechanisms in cancer.

Medcomm

Lei, Zi-Ning ZN; Tian, Qin Q; Teng, Qiu-Xu QX; Wurpel, John N D JND; Zeng, Leli L; Pan, Yihang Y; Chen, Zhe-Sheng ZS

Publication Date: 2023-06

Variant appearance in text: ALK: L1152R

PubMed Link: 37229486

Variant Present in the following documents:

• Main text
• MCO2-4-e265.pdf

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Iruplinalkib (WX‑0593), a novel ALK/ROS1 inhibitor, overcomes crizotinib resistance in preclinical models for non-small cell lung cancer.

Investigational New Drugs

Yang, Yingying Y; Zheng, Qingmei Q; Wang, Xinmei X; Zhao, Shuyong S; Huang, Wenshu W; Jia, Linchao L; Ma, Cuicui C; Liu, Shicong S; Zhang, Yongpeng Y; Xin, Qianqian Q; Sun, Yan Y; Zheng, Shansong S

Publication Date: 2023-04-10

Variant appearance in text: ALK: L1152R

PubMed Link: 37036582

Variant Present in the following documents:

• Main text
• 10637_2023_Article_1350.pdf

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Direct GDP-KRASG12C inhibitors and mechanisms of resistance: the tip of the iceberg.

Therapeutic Advances In Medical Oncology

Rosen, Joshua C JC; Sacher, Adrian A; Tsao, Ming-Sound MS

Publication Date: 2023

Variant appearance in text: ALK: L1152R

PubMed Link: 36950276

Variant Present in the following documents:

• Main text
• 10.1177_17588359231160141.pdf

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First case report of ensartinib in a patient with metastatic ALK rearranged lung cancer with ALK I1171N mutation: a case report.

World Journal Of Surgical Oncology

Yang, Shuang S; Feng, Weineng W; Deng, Yanming Y; Liang, Jianmiao J

Publication Date: 2023-03-02

Variant appearance in text: ALK: L1152R

PubMed Link: 36864442

Variant Present in the following documents:

• Main text
• 12957_2023_Article_2935.pdf

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Ensartinib in advanced ALK-positive non-small cell lung cancer: a multicenter, open-label, two-staged, phase 1 trial.

Journal Of Thoracic Disease

Ma, Yuxiang Y; Pan, Hui H; Liu, Yu Y; Zhang, Yang Y; Hong, Shaodong S; Huang, Jianjin J; Weng, Shanshan S; Yang, Yunpeng Y; Fang, Wenfeng W; Huang, Yan Y; Xiao, Shanshan S; Wang, Tao T; Ding, Lieming L; Cui, Lingling L; Zhang, Li L; Zhao, Hongyun H

Publication Date: 2022-12

Variant appearance in text: ALK: L1152R

PubMed Link: 36647478

Variant Present in the following documents:

• Main text
• jtd-14-12-4751.pdf

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Coexistence of anaplastic lymphoma kinase rearrangement in lung adenocarcinoma harbouring epidermal growth factor receptor mutation: A single-center study.

World Journal Of Clinical Cases

Zhong, Wei-Xiang WX; Wei, Xi-Feng XF

Publication Date: 2022-11-26

Variant appearance in text: ALK: L1152R

PubMed Link: 36483819

Variant Present in the following documents:

• WJCC-10-12164.pdf

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Applications of Liquid Biopsies in Non-Small-Cell Lung Cancer.

Diagnostics (Basel, Switzerland)

Pesta, Martin M; Shetti, Dattatrya D; Kulda, Vlastimil V; Knizkova, Tereza T; Houfkova, Katerina K; Bagheri, Mahyar Sharif MS; Svaton, Martin M; Polivka, Jiri J

Publication Date: 2022-07-25

Variant appearance in text: ALK: L1152R

PubMed Link: 35892510

Variant Present in the following documents:

• Main text
• diagnostics-12-01799.pdf

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The Change in Paradigm for NSCLC Patients with EML4-ALK Translocation.

International Journal Of Molecular Sciences

Bearz, Alessandra A; De Carlo, Elisa E; Del Conte, Alessandro A; Spina, Michele M; Da Ros, Valentina V; Bertoli, Elisa E; Revelant, Alberto A; Stanzione, Brigida B; Tirelli, Umberto U

Publication Date: 2022-06-30

Variant appearance in text: ALK: L1152R

PubMed Link: 35806325

Variant Present in the following documents:

• Main text
• ijms-23-07322.pdf

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Molecular landscape and therapeutic alterations in Asian soft-tissue sarcoma patients.

Cancer Medicine

Gan, Meifu M; Zhang, Chen C; Qiu, Liqing L; Wang, Yue Y; Bao, Hua H; Yu, Ruoying R; Liu, Rui R; Wu, Xue X; Shao, Yang Y; Hou, Peifeng P; Fei, Zhenglei Z

Publication Date: 2022-11

Variant appearance in text: ALK: 3455T>G; L1152R

PubMed Link: 35586877

Variant Present in the following documents:

• CAM4-11-4070-s004.xlsx, sheet 1

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Role of STK11 in ALK-positive non-small cell lung cancer.

Oncology Letters

Zhou, Wen W; Yan, Lu-Da LD; Yu, Zhi-Qiong ZQ; Li, Na N; Yang, Yong-Hua YH; Wang, Meng M; Chen, Yuan-Yuan YY; Mao, Meng-Xia MX; Peng, Xiao-Chun XC; Cai, Jun J

Publication Date: 2022-06

Variant appearance in text: ALK: L1152R

PubMed Link: 35527776

Variant Present in the following documents:

• Main text
• ol-23-06-13301.pdf

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Successful treatment of refractory brain metastases from ALK-positive lung cancer with lorlatinib.

Thoracic Cancer

Nakagawa, Yoshiko Y; Shimizu, Tetsuo T; Hiranuma, Hisato H; Gon, Yasuhiro Y

Publication Date: 2022-05

Variant appearance in text: ALK: L1152R

PubMed Link: 35373538

Variant Present in the following documents:

• Main text
• TCA-13-1431.pdf

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Systematic review and meta-analysis of genomic alterations in acral melanoma.

Pigment Cell & Melanoma Research

Broit, Natasa N; Johansson, Peter A PA; Rodgers, Chloe B CB; Walpole, Sebastian T ST; Hayward, Nicholas K NK; Pritchard, Antonia L AL

Publication Date: 2022-05

Variant appearance in text: ALK: L1152R

PubMed Link: 35229492

Variant Present in the following documents:

• PCMR-35-369-s003.xlsx, sheet 12

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The Molecular Tumor Board Portal supports clinical decisions and automated reporting for precision oncology.

Nature Cancer

Tamborero, David D; Dienstmann, Rodrigo R; Rachid, Maan Haj MH; Boekel, Jorrit J; Lopez-Fernandez, Adria A; Jonsson, Markus M; Razzak, Ali A; Braña, Irene I; De Petris, Luigi L; Yachnin, Jeffrey J; Baird, Richard D RD; Loriot, Yohann Y; Massard, Christophe C; Martin-Romano, Patricia P; Opdam, Frans F; Schlenk, Richard F RF; Vernieri, Claudio C; Masucci, Michele M; Villalobos, Xenia X; Chavarria, Elena E; , ; Balmaña, Judith J; Apolone, Giovanni G; Caldas, Carlos C; Bergh, Jonas J; Ernberg, Ingemar I; Fröhling, Stefan S; Garralda, Elena E; Karlsson, Claes C; Tabernero, Josep J; Voest, Emile E; Rodon, Jordi J; Lehtiö, Janne J

Publication Date: 2022-02

Variant appearance in text: ALK: Leu1152Arg

PubMed Link: 35221333

Variant Present in the following documents:

• 43018_2022_332_MOESM3_ESM.xlsx, sheet 1

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Real-world circulating tumor DNA analysis depicts resistance mechanism and clonal evolution in ALK inhibitor-treated lung adenocarcinoma patients.

Esmo Open

Hua, G G; Zhang, X X; Zhang, M M; Wang, Q Q; Chen, X X; Yu, R R; Bao, H H; Liu, J J; Wu, X X; Shao, Y Y; Liang, B B; Lu, K K

Publication Date: 2022-02

Variant appearance in text: ALK: L1152R

PubMed Link: 35123209

Variant Present in the following documents:

• main.pdf

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Real-world circulating tumor DNA analysis depicts resistance mechanism and clonal evolution in ALK inhibitor-treated lung adenocarcinoma patients.

Esmo Open

Hua, G G; Zhang, X X; Zhang, M M; Wang, Q Q; Chen, X X; Yu, R R; Bao, H H; Liu, J J; Wu, X X; Shao, Y Y; Liang, B B; Lu, K K

Publication Date: 2022-02-02

Variant appearance in text: ALK: L1152R

PubMed Link: 35123209

Variant Present in the following documents:

• main.pdf

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Current Insights on the Treatment of Anaplastic Lymphoma Kinase-Positive Metastatic Non-Small Cell Lung Cancer: Focus on Brigatinib.

Clinical Pharmacology : Advances And Applications

Rijavec, Erika E; Biello, Federica F; Indini, Alice A; Grossi, Francesco F; Genova, Carlo C

Publication Date: 2022

Variant appearance in text: ALK: L1152R

PubMed Link: 35082536

Variant Present in the following documents:

• Main text
• cpaa-14-1.pdf

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: ALK: 3455T>G; Leu1152Arg

PubMed Link: 35031014

Variant Present in the following documents:

• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Investigating the genomic alteration improved the clinical outcome of aged patients with lung carcinoma.

Bmc Genomics

Chen, Sixian S; Fu, Aizhen A; Lu, Yuan Y; Lu, Wei W; Chen, Yongfeng Y; Hong, Shuiqiang S; Zhou, Suli S; Xiang, Tianmin T; Zhang, Zhenzhen Z; Cai, Yongguang Y

Publication Date: 2022-01-15

Variant appearance in text: ALK: 3455T>G; Leu1152Arg

PubMed Link: 35031014

Variant Present in the following documents:

• 12864_2021_8289_MOESM1_ESM.xlsx, sheet 1

View BVdb publication page

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Identification of triple gene fusion ALK-LRRN2, LTBP1-ALK, and HIP1-ALK in advanced lung adenocarcinoma and response to alectinib: A case report.

Medicine

Ning, Shangkun S; Shi, Congcong C; Zhang, Huifang H; Li, Jinpeng J

Publication Date: 2021-12-23

Variant appearance in text: ALK: L1152R

PubMed Link: 34941039

Variant Present in the following documents:

• Main text
• medi-100-e27999.pdf

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Identification of triple gene fusion ALK-LRRN2, LTBP1-ALK, and HIP1-ALK in advanced lung adenocarcinoma and response to alectinib: A case report.

Medicine

Ning, Shangkun S; Shi, Congcong C; Zhang, Huifang H; Li, Jinpeng J

Publication Date: 2021-12-23

Variant appearance in text: ALK: L1152R

PubMed Link: 34941039

Variant Present in the following documents:

• Main text
• medi-100-e27999.pdf

View BVdb publication page

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Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers

Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD

Publication Date: 2021-11-29

Variant appearance in text: ALK: L1152R

PubMed Link: 34885113

Variant Present in the following documents:

• Main text
• cancers-13-06003.pdf

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Resistance to Targeted Agents Used to Treat Paediatric ALK-Positive ALCL.

Cancers

Hare, Lucy L; Burke, G A Amos GAA; Turner, Suzanne D SD

Publication Date: 2021-11-29

Variant appearance in text: ALK: L1152R

PubMed Link: 34885113

Variant Present in the following documents:

• Main text
• cancers-13-06003.pdf

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Two novel strategies to overcome the resistance to ALK tyrosine kinase inhibitor drugs: Macrocyclic inhibitors and proteolysis-targeting chimeras.

Medcomm

Song, Xiaoling X; Zhong, Hui H; Qu, Xiaojuan X; Yang, Linsong L; Jiang, Biao B

Publication Date: 2021-09

Variant appearance in text: ALK: L1152R

PubMed Link: 34766150

Variant Present in the following documents:

• Main text
• MCO2-2-341.pdf

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New Advances in Liquid Biopsy Technologies for Anaplastic Lymphoma Kinase (ALK)-Positive Cancer.

Cancers

Villa, Matteo M; Sharma, Geeta G GG; Manfroni, Chiara C; Cortinovis, Diego D; Mologni, Luca L

Publication Date: 2021-10-14

Variant appearance in text: ALK: L1152R

PubMed Link: 34680298

Variant Present in the following documents:

• Main text

View BVdb publication page

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The Resistance Mechanisms and Treatment Strategies for ALK-Rearranged Non-Small Cell Lung Cancer.

Frontiers In Oncology

Pan, Yue Y; Deng, Chao C; Qiu, Zhenhua Z; Cao, Chenghui C; Wu, Fang F

Publication Date: 2021

Variant appearance in text: ALK: L1152R

PubMed Link: 34660278

Variant Present in the following documents:

• Main text

View BVdb publication page

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Genetic and treatment profiles of patients with concurrent Epidermal Growth Factor Receptor (EGFR) and Anaplastic Lymphoma Kinase (ALK) mutations.

Bmc Cancer

Yang, Xiaodan X; Zhong, Jia J; Yu, Zhuo Z; Zhuo, Minglei M; Zhang, Min M; Chen, Rongrong R; Xia, Xuefeng X; Zhao, Jun J

Publication Date: 2021-10-15

Variant appearance in text: ALK: L1152R

PubMed Link: 34654390

Variant Present in the following documents:

• Main text
• 12885_2021_Article_8824.pdf

View BVdb publication page

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Targeted Therapy of Papillary Thyroid Cancer: A Comprehensive Genomic Analysis.

Frontiers In Endocrinology

Hescheler, Daniel A DA; Riemann, Burkhard B; Hartmann, Milan J M MJM; Michel, Maximilian M; Faust, Michael M; Bruns, Christiane J CJ; Alakus, Hakan H; Chiapponi, Costanza C

Publication Date: 2021

Variant appearance in text: ALK: L1152R

PubMed Link: 34630336

Variant Present in the following documents:

• Table_1.xlsx, sheet 2

View BVdb publication page

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Clinicopathological and prognostic implications of ALK rearrangement in patients with completely surgically resected lung adenocarcinoma.

Thoracic Cancer

Zhang, Huan H; Shan, Guangyao G; Cai, Benjie B; Bi, Guoshu G; Chen, Zhencong Z; Liang, Jiaqi J; Besskaya, Valeria V; Zheng, Yuansheng Y; Guo, Weigang W; Wang, Lin L; Xu, Songtao S; Zhan, Cheng C

Publication Date: 2021-11

Variant appearance in text: ALK: L1152R

PubMed Link: 34596344

Variant Present in the following documents:

• Main text
• TCA-12-3011.pdf

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Clinicopathological and prognostic implications of ALK rearrangement in patients with completely surgically resected lung adenocarcinoma.

Thoracic Cancer

Zhang, Huan H; Shan, Guangyao G; Cai, Benjie B; Bi, Guoshu G; Chen, Zhencong Z; Liang, Jiaqi J; Besskaya, Valeria V; Zheng, Yuansheng Y; Guo, Weigang W; Wang, Lin L; Xu, Songtao S; Zhan, Cheng C

Publication Date: 2021-11

Variant appearance in text: ALK: L1152R

PubMed Link: 34596344

Variant Present in the following documents:

• Main text
• TCA-12-3011.pdf

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Clinical Utility of Liquid Biopsy-Based Actionable Mutations Detected via ddPCR.

Biomedicines

Palacín-Aliana, Irina I; García-Romero, Noemí N; Asensi-Puig, Adrià A; Carrión-Navarro, Josefa J; González-Rumayor, Víctor V; Ayuso-Sacido, Ángel Á

Publication Date: 2021-07-28

Variant appearance in text: ALK: L1152R

PubMed Link: 34440110

Variant Present in the following documents:

• Main text

View BVdb publication page

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Will the clinical development of 4th-generation "double mutant active" ALK TKIs (TPX-0131 and NVL-655) change the future treatment paradigm of ALK+ NSCLC?

Translational Oncology

Ou, Sai-Hong Ignatius SI; Nagasaka, Misako M; Brazel, Danielle D; Hou, Yujie Y; Zhu, Viola W VW

Publication Date: 2021-11

Variant appearance in text: ALK: L1152R

PubMed Link: 34365220

Variant Present in the following documents:

• Main text

View BVdb publication page

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Update on molecular pathology and role of liquid biopsy in nonsmall cell lung cancer.

European Respiratory Review : An Official Journal Of The European Respiratory Society

Abdayem, Pamela P; Planchard, David D

Publication Date: 2021-09-30

Variant appearance in text: ALK: L1152R

PubMed Link: 34289984

Variant Present in the following documents:

• Main text
• ERR-0294-2020.pdf

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Association of anaplastic lymphoma kinase variants and alterations with ensartinib response duration in non-small cell lung cancer.

Thoracic Cancer

Hou, Donghui D; Zheng, Xiaomin X; Song, Wei W; Liu, Xiaoqing X; Wang, Sicong S; Zhou, Lina L; Tao, Xiuli X; Lv, Lv L; Sun, Qi Q; Jin, Yujing Y; Zhang, Zewei Z; Ding, Lieming L; Wu, Ning N; Zhao, Shijun S

Publication Date: 2021-09

Variant appearance in text: ALK: L1152R

PubMed Link: 34288491

Variant Present in the following documents:

• Main text
• TCA-12-2388.pdf

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Association of anaplastic lymphoma kinase variants and alterations with ensartinib response duration in non-small cell lung cancer.

Thoracic Cancer

Hou, Donghui D; Zheng, Xiaomin X; Song, Wei W; Liu, Xiaoqing X; Wang, Sicong S; Zhou, Lina L; Tao, Xiuli X; Lv, Lv L; Sun, Qi Q; Jin, Yujing Y; Zhang, Zewei Z; Ding, Lieming L; Wu, Ning N; Zhao, Shijun S

Publication Date: 2021-09

Variant appearance in text: ALK: L1152R

PubMed Link: 34288491

Variant Present in the following documents:

• Main text
• TCA-12-2388.pdf

View BVdb publication page

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One-Step Polymerase Chain Reaction-Free Nanowire-Based Plasma Cell-Free DNA Assay to Detect EML4-ALK Fusion and to Monitor Resistance in Lung Cancer.

The Oncologist

Lee, Youngjoo Y; Cho, Youngnam Y; Park, Eun Young EY; Park, Seong-Yun SY; Hwang, Kum Hui KH; Han, Ji-Youn JY

Publication Date: 2021-10

Variant appearance in text: ALK: L1152R

PubMed Link: 34272914

Variant Present in the following documents:

• Main text

View BVdb publication page

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Response to lorlatinib on a patient with ALK-rearranged non-small cell lung cancer harboring 1151Tins mutation with uterine metastasis.

Thoracic Cancer

Kobayashi, Takashi T; Kanda, Shintaro S; Fukushima, Toshirou T; Noguchi, Takuro T; Sekiguchi, Nodoka N; Koizumi, Tomonobu T

Publication Date: 2021-08

Variant appearance in text: ALK: L1152R

PubMed Link: 34184417

Variant Present in the following documents:

• Main text
• TCA-12-2275.pdf

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TPX-0131, a Potent CNS-penetrant, Next-generation Inhibitor of Wild-type ALK and ALK-resistant Mutations.

Molecular Cancer Therapeutics

Murray, Brion W BW; Zhai, Dayong D; Deng, Wei W; Zhang, Xin X; Ung, Jane J; Nguyen, Vivian V; Zhang, Han H; Barrera, Maria M; Parra, Ana A; Cowell, Jessica J; Lee, Dong J DJ; Aloysius, Herve H; Rogers, Evan E

Publication Date: 2021-09

Variant appearance in text: ALK: L1152R

PubMed Link: 34158340

Variant Present in the following documents:

• Main text
• 1499.pdf

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Pathological complete response to neoadjuvant ceritinib of a crizotinib-resistant, stage IIIB non-small cell lung cancer with ALK rearrangement: A case report.

Thoracic Cancer

Bing, Zhongxing Z; Jia, Ziqi Z; Wang, Yadong Y; Xue, Jianchao J; Cao, Lei L; Cao, Zhili Z; Liu, Peng P; Li, Ji J; Liang, Naixin N; Li, Shanqing S

Publication Date: 2021-07

Variant appearance in text: ALK: L1152R

PubMed Link: 34105864

Variant Present in the following documents:

• Main text

View BVdb publication page

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A review of the biological and clinical implications of RAS-MAPK pathway alterations in neuroblastoma.

Journal Of Experimental & Clinical Cancer Research : Cr

Mlakar, Vid V; Morel, Edouard E; Mlakar, Simona Jurkovic SJ; Ansari, Marc M; Gumy-Pause, Fabienne F

Publication Date: 2021-06-08

Variant appearance in text: ALK: L1152R

PubMed Link: 34103089

Variant Present in the following documents:

• Main text

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An insight into lung cancer: a comprehensive review exploring ALK TKI and mechanisms of resistance.

Bosnian Journal Of Basic Medical Sciences

Patcas, Adela A; Chis, Ana Florica AF; Militaru, Claudia Florentina CF; Bordea, Ioana Roxana IR; Rajnoveanu, Ruxandra R; Coza, Ovidiu Florin OF; Hanna, Reem R; Tiberiu, Tamas T; Todea, Doina Adina DA

Publication Date: 2022-02-01

Variant appearance in text: ALK: L1152R

PubMed Link: 34082691

Variant Present in the following documents:

• Main text
• BJBMS-22-1.pdf

View BVdb publication page

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Kinase drug discovery 20 years after imatinib: progress and future directions.

Nature Reviews. Drug Discovery

Cohen, Philip P; Cross, Darren D; Jänne, Pasi A PA

Publication Date: 2021-07

Variant appearance in text: ALK: L1152R

PubMed Link: 34002056

Variant Present in the following documents:

• Main text
• 41573_2021_Article_195.pdf

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Intratumoral Cellular Heterogeneity: Implications for Drug Resistance in Patients with Non-Small Cell Lung Cancer.

Cancers

Gregorc, Vanesa V; Lazzari, Chiara C; Mandalá, Mario M; Ippati, Stefania S; Bulotta, Alessandra A; Cangi, Maria Giulia MG; Khater, Abdelrahman A; Viganò, Maria Grazia MG; Mirabile, Aurora A; Pecciarini, Lorenza L; Ogliari, Francesca Rita FR; Arrigoni, Gianluigi G; Grassini, Greta G; Veronesi, Giulia G; Doglioni, Claudio C

Publication Date: 2021-04-22

Variant appearance in text: ALK: L1152R

PubMed Link: 33922215

Variant Present in the following documents:

• Main text

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Future Perspectives in Detecting EGFR and ALK Gene Alterations in Liquid Biopsies of Patients with NSCLC.

International Journal Of Molecular Sciences

Ferreira, Daniela D; Miranda, Juliana J; Martins-Lopes, Paula P; Adega, Filomena F; Chaves, Raquel R

Publication Date: 2021-04-07

Variant appearance in text: ALK: L1152R

PubMed Link: 33916986

Variant Present in the following documents:

• Main text

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Microsecond-timescale MD simulation of EGFR minor mutation predicts the structural flexibility of EGFR kinase core that reflects EGFR inhibitor sensitivity.

Npj Precision Oncology

Yoshizawa, Takahiro T; Uchibori, Ken K; Araki, Mitsugu M; Matsumoto, Shigeyuki S; Ma, Biao B; Kanada, Ryo R; Seto, Yosuke Y; Oh-Hara, Tomoko T; Koike, Sumie S; Ariyasu, Ryo R; Kitazono, Satoru S; Ninomiya, Hironori H; Takeuchi, Kengo K; Yanagitani, Noriko N; Takagi, Satoshi S; Kishi, Kazuma K; Fujita, Naoya N; Okuno, Yasushi Y; Nishio, Makoto M; Katayama, Ryohei R

Publication Date: 2021-04-16

Variant appearance in text: ALK: L1152R

PubMed Link: 33863983

Variant Present in the following documents:

• Main text
• 41698_2021_Article_170.pdf

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Current Knowledge about Mechanisms of Drug Resistance against ALK Inhibitors in Non-Small Cell Lung Cancer.

Cancers

Smolle, Elisabeth E; Taucher, Valentin V; Lindenmann, Joerg J; Jost, Philipp J PJ; Pichler, Martin M

Publication Date: 2021-02-09

Variant appearance in text: ALK: L1152R

PubMed Link: 33572278

Variant Present in the following documents:

• Main text
• cancers-13-00699.pdf

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Overcoming TKI resistance in fusion-driven NSCLC: new generation inhibitors and rationale for combination strategies.

Translational Lung Cancer Research

Russo, Alessandro A; Cardona, Andrés F AF; Caglevic, Christian C; Manca, Paolo P; Ruiz-Patiño, Alejandro A; Arrieta, Oscar O; Rolfo, Christian C

Publication Date: 2020-12

Variant appearance in text: ALK: L1152R

PubMed Link: 33489820

Variant Present in the following documents:

• Main text
• tlcr-09-06-2581.pdf

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Detecting Resistance to Therapeutic ALK Inhibitors in Tumor Tissue and Liquid Biopsy Markers: An Update to a Clinical Routine Practice.

Cells

Hofman, Paul P

Publication Date: 2021-01-15

Variant appearance in text: ALK: L1152R

PubMed Link: 33467720

Variant Present in the following documents:

• Main text
• cells-10-00168.pdf

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