ALK c.3449A>G ;(p.K1150R)

Variant ID: 2-29445384-T-C

NM_004304.4(ALK):c.3449A>G;(p.K1150R)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Analytical Validation of a Hybrid Capture-Based Next-Generation Sequencing Clinical Assay for Genomic Profiling of Cell-Free Circulating Tumor DNA.

The Journal Of Molecular Diagnostics : Jmd
Clark, Travis A TA; Chung, Jon H JH; Kennedy, Mark M; Hughes, Jason D JD; Chennagiri, Niru N; Lieber, Daniel S DS; Fendler, Bernard B; Young, Lauren L; Zhao, Mandy M; Coyne, Michael M; Breese, Virginia V; Young, Geneva G; Donahue, Amy A; Pavlick, Dean D; Tsiros, Alyssa A; Brennan, Timothy T; Zhong, Shan S; Mughal, Tariq T; Bailey, Mark M; He, Jie J; Roels, Steven S; Frampton, Garrett M GM; Spoerke, Jill M JM; Gendreau, Steven S; Lackner, Mark M; Schleifman, Erica E; Peters, Eric E; Ross, Jeffrey S JS; Ali, Siraj M SM; Miller, Vincent A VA; Gregg, Jeffrey P JP; Stephens, Philip J PJ; Welsh, Allison A; Otto, Geoff A GA; Lipson, Doron D
Publication Date: 2018-09

Variant appearance in text: ALK: K1150R
PubMed Link: 29936259
Variant Present in the following documents:
  • mmc12.xlsx, sheet 1
View BVdb publication page



Machine Learning Detects Pan-cancer Ras Pathway Activation in The Cancer Genome Atlas.

Cell Reports
Way, Gregory P GP; Sanchez-Vega, Francisco F; La, Konnor K; Armenia, Joshua J; Chatila, Walid K WK; Luna, Augustin A; Sander, Chris C; Cherniack, Andrew D AD; Mina, Marco M; Ciriello, Giovanni G; Schultz, Nikolaus N; , ; Sanchez, Yolanda Y; Greene, Casey S CS
Publication Date: 2018-04-03

Variant appearance in text: ALK: Lys1150Arg
PubMed Link: 29617658
Variant Present in the following documents:
  • NIHMS958974-supplement-6.xlsx, sheet 1
View BVdb publication page



Identification of oncogenic point mutations and hyperphosphorylation of anaplastic lymphoma kinase in lung cancer.

Neoplasia (New York, N.Y.)
Wang, Yi-Wei YW; Tu, Pang-Hsien PH; Lin, Kuen-Tyng KT; Lin, Shu-Chen SC; Ko, Jenq-Yuh JY; Jou, Yuh-Shan YS
Publication Date: 2011-08

Variant appearance in text: ALK: K1150R
PubMed Link: 21847362
Variant Present in the following documents:
  • Main text
View BVdb publication page



Anaplastic lymphoma kinase is a dependence receptor whose proapoptotic functions are activated by caspase cleavage.

Molecular And Cellular Biology
Mourali, Jaouhar J; Bénard, Alan A; Lourenço, Filipe Calheiros FC; Monnet, Céline C; Greenland, Catherine C; Moog-Lutz, Christel C; Racaud-Sultan, Claire C; Gonzalez-Dunia, Daniel D; Vigny, Marc M; Mehlen, Patrick P; Delsol, Georges G; Allouche, Michèle M
Publication Date: 2006-08

Variant appearance in text: ALK: K1150R
PubMed Link: 16880530
Variant Present in the following documents:
  • Main text
View BVdb publication page