ALK c.3446T>C ;(p.V1149A)

Variant ID: 2-29445387-A-G

NM_004304.4(ALK):c.3446T>C;(p.V1149A)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Earlier extracranial progression and shorter survival in ALK-rearranged lung cancer with positive liquid rebiopsies.

Translational Lung Cancer Research
Christopoulos, Petros P; Dietz, Steffen S; Angeles, Arlou K AK; Rheinheimer, Stephan S; Kazdal, Daniel D; Volckmar, Anna-Lena AL; Janke, Florian F; Endris, Volker V; Meister, Michael M; Kriegsmann, Mark M; Zemojtel, Thomasz T; Reck, Martin M; Stenzinger, Albrecht A; Thomas, Michael M; Sültmann, Holger H
Publication Date: 2021-05

Variant appearance in text: ALK: V1149A
PubMed Link: 34164264
Variant Present in the following documents:
  • tlcr-10-05-2118-supplementary.pdf
View BVdb publication page



Lorlatinib in pretreated ALK- or ROS1-positive lung cancer and impact of TP53 co-mutations: results from the German early access program.

Therapeutic Advances In Medical Oncology
Frost, Nikolaj N; Christopoulos, Petros P; Kauffmann-Guerrero, Diego D; Stratmann, Jan J; Riedel, Richard R; Schaefer, Monica M; Alt, Jürgen J; Gütz, Sylvia S; Christoph, Daniel C DC; Laack, Eckart E; Faehling, Martin M; Fischer, Richard R; Fenchel, Klaus K; Haen, Sebastian S; Heukamp, Lukas L; Schulz, Christian C; Griesinger, Frank F
Publication Date: 2021

Variant appearance in text: ALK: V1149A
PubMed Link: 33613692
Variant Present in the following documents:
  • Main text
  • 10.1177_1758835920980558.pdf
View BVdb publication page



Longitudinal therapy monitoring of ALK-positive lung cancer by combined copy number and targeted mutation profiling of cell-free DNA.

Ebiomedicine
Dietz, Steffen S; Christopoulos, Petros P; Yuan, Zhao Z; Angeles, Arlou Kristina AK; Gu, Lisa L; Volckmar, Anna-Lena AL; Ogrodnik, Simon J SJ; Janke, Florian F; Fratte, Chiara Dalle CD; Zemojtel, Tomasz T; Schneider, Marc A MA; Kazdal, Daniel D; Endris, Volker V; Meister, Michael M; Muley, Thomas T; Cecchin, Erika E; Reck, Martin M; Schlesner, Matthias M; Thomas, Michael M; Stenzinger, Albrecht A; Sültmann, Holger H
Publication Date: 2020-12

Variant appearance in text: ALK: 3446T>C; V1149A
PubMed Link: 33161228
Variant Present in the following documents:
  • Main text
  • main.pdf
  • mmc1.pdf
View BVdb publication page



Single C-to-T substitution using engineered APOBEC3G-nCas9 base editors with minimum genome- and transcriptome-wide off-target effects.

Science Advances
Lee, Sangsin S; Ding, Ning N; Sun, Yidi Y; Yuan, Tanglong T; Li, Jing J; Yuan, Qichen Q; Liu, Lizhong L; Yang, Jie J; Wang, Qian Q; Kolomeisky, Anatoly B AB; Hilton, Isaac B IB; Zuo, Erwei E; Gao, Xue X
Publication Date: 2020-07

Variant appearance in text: ALK: 3446T>C
PubMed Link: 32832622
Variant Present in the following documents:
  • aba1773_Data_file_S1.xlsx, sheet 2
View BVdb publication page