Small molecule inhibition of Dynamin-dependent endocytosis targets multiple niche signals and impairs leukemia stem cells.
Nature Communications
Tremblay, Cedric S CS; Chiu, Sung Kai SK; Saw, Jesslyn J; McCalmont, Hannah H; Litalien, Veronique V; Boyle, Jacqueline J; Sonderegger, Stefan E SE; Chau, Ngoc N; Evans, Kathryn K; Cerruti, Loretta L; Salmon, Jessica M JM; McCluskey, Adam A; Lock, Richard B RB; Robinson, Phillip J PJ; Jane, Stephen M SM; Curtis, David J DJ
Quantitative phosphotyrosine profiling of patient-derived xenografts identifies therapeutic targets in pediatric leukemia.
Cancer Research
Dolai, Sibasish S; Sia, Keith C S KC; Robbins, Alissa K AK; Zhong, Ling L; Heatley, Sue L SL; Vincent, Tiffaney L TL; Hochgräfe, Falko F; Sutton, Rosemary R; Kurmasheva, Raushan T RT; Revesz, Tamas T; White, Deborah L DL; Houghton, Peter J PJ; Smith, Malcolm A MA; Teachey, David T DT; Daly, Roger J RJ; Raftery, Mark J MJ; Lock, Richard B RB