Comprehensive genetic analysis of the human lipidome identifies loci associated with lipid homeostasis with links to coronary artery disease.
Nature Communications
Cadby, Gemma G; Giles, Corey C; Melton, Phillip E PE; Huynh, Kevin K; Mellett, Natalie A NA; Duong, Thy T; Nguyen, Anh A; Cinel, Michelle M; Smith, Alex A; Olshansky, Gavriel G; Wang, Tingting T; Brozynska, Marta M; Inouye, Mike M; McCarthy, Nina S NS; Ariff, Amir A; Hung, Joseph J; Hui, Jennie J; Beilby, John J; Dubé, Marie-Pierre MP; Watts, Gerald F GF; Shah, Sonia S; Wray, Naomi R NR; Lim, Wei Ling Florence WLF; Chatterjee, Pratishtha P; Martins, Ian I; Laws, Simon M SM; Porter, Tenielle T; Vacher, Michael M; Bush, Ashley I AI; Rowe, Christopher C CC; Villemagne, Victor L VL; Ames, David D; Masters, Colin L CL; Taddei, Kevin K; Arnold, Matthias M; Kastenmüller, Gabi G; Nho, Kwangsik K; Saykin, Andrew J AJ; Han, Xianlin X; Kaddurah-Daouk, Rima R; Martins, Ralph N RN; Blangero, John J; Meikle, Peter J PJ; Moses, Eric K EK
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.
Nature Communications
Yin, Xianyong X; Chan, Lap Sum LS; Bose, Debraj D; Jackson, Anne U AU; VandeHaar, Peter P; Locke, Adam E AE; Fuchsberger, Christian C; Stringham, Heather M HM; Welch, Ryan R; Yu, Ketian K; Fernandes Silva, Lilian L; Service, Susan K SK; Zhang, Daiwei D; Hector, Emily C EC; Young, Erica E; Ganel, Liron L; Das, Indraniel I; Abel, Haley H; Erdos, Michael R MR; Bonnycastle, Lori L LL; Kuusisto, Johanna J; Stitziel, Nathan O NO; Hall, Ira M IM; Wagner, Gregory R GR; , ; Kang, Jian J; Morrison, Jean J; Burant, Charles F CF; Collins, Francis S FS; Ripatti, Samuli S; Palotie, Aarno A; Freimer, Nelson B NB; Mohlke, Karen L KL; Scott, Laura J LJ; Wen, Xiaoquan X; Fauman, Eric B EB; Laakso, Markku M; Boehnke, Michael M
Polymorphisms in Genes of Lipid Metabolism Are Associated with Type 2 Diabetes Mellitus and Periodontitis, as Comorbidities, and with the Subjects' Periodontal, Glycemic, and Lipid Profiles.
Journal Of Diabetes Research
Nicchio, Ingra G IG; Cirelli, Thamiris T; Nepomuceno, Rafael R; Hidalgo, Marco A R MAR; Rossa, Carlos C; Cirelli, Joni A JA; Orrico, Silvana R P SRP; Barros, Silvana P SP; Theodoro, Letícia H LH; Scarel-Caminaga, Raquel M RM
Cardiovascular risk factor mediation of the effects of education and Genetic Risk Score on cardiovascular disease: a prospective observational cohort study of the Framingham Heart Study.
Bmj Open
Powell, Katie L KL; Stephens, Sebastien R SR; Stephens, Alexandre S AS
Prioritization of causal genes for coronary artery disease based on cumulative evidence from experimental and in silico studies.
Scientific Reports
Shadrina, Alexandra S AS; Shashkova, Tatiana I TI; Torgasheva, Anna A AA; Sharapov, Sodbo Z SZ; Klarić, Lucija L; Pakhomov, Eugene D ED; Alexeev, Dmitry G DG; Wilson, James F JF; Tsepilov, Yakov A YA; Joshi, Peter K PK; Aulchenko, Yurii S YS
Six years' experience with LipidSeq: clinical and research learnings from a hybrid, targeted sequencing panel for dyslipidemias.
Bmc Medical Genomics
Dron, Jacqueline S JS; Wang, Jian J; McIntyre, Adam D AD; Iacocca, Michael A MA; Robinson, John F JF; Ban, Matthew R MR; Cao, Henian H; Hegele, Robert A RA
Druggability of Coronary Artery Disease Risk Loci.
Circulation. Genomic And Precision Medicine
Tragante, Vinicius V; Hemerich, Daiane D; Alshabeeb, Mohammad M; Brænne, Ingrid I; Lempiäinen, Harri H; Patel, Riyaz S RS; den Ruijter, Hester M HM; Barnes, Michael R MR; Moore, Jason H JH; Schunkert, Heribert H; Erdmann, Jeanette J; Asselbergs, Folkert W FW
Using an atlas of gene regulation across 44 human tissues to inform complex disease- and trait-associated variation.
Nature Genetics
Gamazon, Eric R ER; Segrè, Ayellet V AV; van de Bunt, Martijn M; Wen, Xiaoquan X; Xi, Hualin S HS; Hormozdiari, Farhad F; Ongen, Halit H; Konkashbaev, Anuar A; Derks, Eske M EM; Aguet, François F; Quan, Jie J; , ; Nicolae, Dan L DL; Eskin, Eleazar E; Kellis, Manolis M; Getz, Gad G; McCarthy, Mark I MI; Dermitzakis, Emmanouil T ET; Cox, Nancy J NJ; Ardlie, Kristin G KG
Evaluation of 71 Coronary Artery Disease Risk Variants in a Multiethnic Cohort.
Frontiers In Cardiovascular Medicine
Ke, Wangjing W; Rand, Kristin A KA; Conti, David V DV; Setiawan, Veronica W VW; Stram, Daniel O DO; Wilkens, Lynne L; Le Marchand, Loic L; Assimes, Themistocles L TL; Haiman, Christopher A CA
Genetic loci associated with coronary artery disease harbor evidence of selection and antagonistic pleiotropy.
Plos Genetics
Byars, Sean G SG; Huang, Qin Qin QQ; Gray, Lesley-Ann LA; Bakshi, Andrew A; Ripatti, Samuli S; Abraham, Gad G; Stearns, Stephen C SC; Inouye, Michael M
Screening for familial hypercholesterolaemia in childhood: Avon Longitudinal Study of Parents and Children (ALSPAC).
Atherosclerosis
Futema, Marta M; Cooper, Jackie A JA; Charakida, Marietta M; Boustred, Christopher C; Sattar, Naveed N; Deanfield, John J; Lawlor, Debbie A DA; Timpson, Nicholas J NJ; , ; Humphries, Steve E SE; Hingorani, Aroon D AD
Genetic contribution to lipid levels in early life based on 158 loci validated in adults: the FAMILY study.
Scientific Reports
Christie, Shanice S; Robiou-du-Pont, Sébastien S; Anand, Sonia S SS; Morrison, Katherine M KM; McDonald, Sarah D SD; Paré, Guillaume G; Atkinson, Stephanie A SA; Teo, Koon K KK; Meyre, David D
Systematic Evaluation of Pleiotropy Identifies 6 Further Loci Associated With Coronary Artery Disease.
Journal Of The American College Of Cardiology
Webb, Thomas R TR; Erdmann, Jeanette J; Stirrups, Kathleen E KE; Stitziel, Nathan O NO; Masca, Nicholas G D NG; Jansen, Henning H; Kanoni, Stavroula S; Nelson, Christopher P CP; Ferrario, Paola G PG; König, Inke R IR; Eicher, John D JD; Johnson, Andrew D AD; Hamby, Stephen E SE; Betsholtz, Christer C; Ruusalepp, Arno A; Franzén, Oscar O; Schadt, Eric E EE; Björkegren, Johan L M JL; Weeke, Peter E PE; Auer, Paul L PL; Schick, Ursula M UM; Lu, Yingchang Y; Zhang, He H; Dube, Marie-Pierre MP; Goel, Anuj A; Farrall, Martin M; Peloso, Gina M GM; Won, Hong-Hee HH; Do, Ron R; van Iperen, Erik E; Kruppa, Jochen J; Mahajan, Anubha A; Scott, Robert A RA; Willenborg, Christina C; Braund, Peter S PS; van Capelleveen, Julian C JC; Doney, Alex S F AS; Donnelly, Louise A LA; Asselta, Rosanna R; Merlini, Pier A PA; Duga, Stefano S; Marziliano, Nicola N; Denny, Josh C JC; Shaffer, Christian C; El-Mokhtari, Nour Eddine NE; Franke, Andre A; Heilmann, Stefanie S; Hengstenberg, Christian C; Hoffmann, Per P; Holmen, Oddgeir L OL; Hveem, Kristian K; Jansson, Jan-Håkan JH; Jöckel, Karl-Heinz KH; Kessler, Thorsten T; Kriebel, Jennifer J; Laugwitz, Karl L KL; Marouli, Eirini E; Martinelli, Nicola N; McCarthy, Mark I MI; Van Zuydam, Natalie R NR; Meisinger, Christa C; Esko, Tõnu T; Mihailov, Evelin E; Escher, Stefan A SA; Alver, Maris M; Moebus, Susanne S; Morris, Andrew D AD; Virtamo, Jarma J; Nikpay, Majid M; Olivieri, Oliviero O; Provost, Sylvie S; AlQarawi, Alaa A; Robertson, Neil R NR; Akinsansya, Karen O KO; Reilly, Dermot F DF; Vogt, Thomas F TF; Yin, Wu W; Asselbergs, Folkert W FW; Kooperberg, Charles C; Jackson, Rebecca D RD; Stahl, Eli E; Müller-Nurasyid, Martina M; Strauch, Konstantin K; Varga, Tibor V TV; Waldenberger, Melanie M; , ; Zeng, Lingyao L; Chowdhury, Rajiv R; Salomaa, Veikko V; Ford, Ian I; Jukema, J Wouter JW; Amouyel, Philippe P; Kontto, Jukka J; , ; Nordestgaard, Børge G BG; Ferrières, Jean J; Saleheen, Danish D; Sattar, Naveed N; Surendran, Praveen P; Wagner, Aline A; Young, Robin R; Howson, Joanna M M JM; Butterworth, Adam S AS; Danesh, John J; Ardissino, Diego D; Bottinger, Erwin P EP; Erbel, Raimund R; Franks, Paul W PW; Girelli, Domenico D; Hall, Alistair S AS; Hovingh, G Kees GK; Kastrati, Adnan A; Lieb, Wolfgang W; Meitinger, Thomas T; Kraus, William E WE; Shah, Svati H SH; McPherson, Ruth R; Orho-Melander, Marju M; Melander, Olle O; Metspalu, Andres A; Palmer, Colin N A CN; Peters, Annette A; Rader, Daniel J DJ; Reilly, Muredach P MP; Loos, Ruth J F RJ; Reiner, Alex P AP; Roden, Dan M DM; Tardif, Jean-Claude JC; Thompson, John R JR; Wareham, Nicholas J NJ; Watkins, Hugh H; Willer, Cristen J CJ; Samani, Nilesh J NJ; Schunkert, Heribert H; Deloukas, Panos P; Kathiresan, Sekar S; ,
Heart Disease and Stroke Statistics-2017 Update: A Report From the American Heart Association.
Circulation
Benjamin, Emelia J EJ; Blaha, Michael J MJ; Chiuve, Stephanie E SE; Cushman, Mary M; Das, Sandeep R SR; Deo, Rajat R; de Ferranti, Sarah D SD; Floyd, James J; Fornage, Myriam M; Gillespie, Cathleen C; Isasi, Carmen R CR; Jiménez, Monik C MC; Jordan, Lori Chaffin LC; Judd, Suzanne E SE; Lackland, Daniel D; Lichtman, Judith H JH; Lisabeth, Lynda L; Liu, Simin S; Longenecker, Chris T CT; Mackey, Rachel H RH; Matsushita, Kunihiro K; Mozaffarian, Dariush D; Mussolino, Michael E ME; Nasir, Khurram K; Neumar, Robert W RW; Palaniappan, Latha L; Pandey, Dilip K DK; Thiagarajan, Ravi R RR; Reeves, Mathew J MJ; Ritchey, Matthew M; Rodriguez, Carlos J CJ; Roth, Gregory A GA; Rosamond, Wayne D WD; Sasson, Comilla C; Towfighi, Amytis A; Tsao, Connie W CW; Turner, Melanie B MB; Virani, Salim S SS; Voeks, Jenifer H JH; Willey, Joshua Z JZ; Wilkins, John T JT; Wu, Jason Hy JH; Alger, Heather M HM; Wong, Sally S SS; Muntner, Paul P; ,
Integrated genome-wide analysis of expression quantitative trait loci aids interpretation of genomic association studies.
Genome Biology
Joehanes, Roby R; Zhang, Xiaoling X; Huan, Tianxiao T; Yao, Chen C; Ying, Sai-Xia SX; Nguyen, Quang Tri QT; Demirkale, Cumhur Yusuf CY; Feolo, Michael L ML; Sharopova, Nataliya R NR; Sturcke, Anne A; Schäffer, Alejandro A AA; Heard-Costa, Nancy N; Chen, Han H; Liu, Po-Ching PC; Wang, Richard R; Woodhouse, Kimberly A KA; Tanriverdi, Kahraman K; Freedman, Jane E JE; Raghavachari, Nalini N; Dupuis, Josée J; Johnson, Andrew D AD; O'Donnell, Christopher J CJ; Levy, Daniel D; Munson, Peter J PJ
Coronary Artery Calcification and Rheumatoid Arthritis: Lack of Relationship to Risk Alleles for Coronary Artery Disease in the General Population.
Arthritis & Rheumatology (Hoboken, N.J.)
Ferraz-Amaro, Iván I; Winchester, Robert R; Gregersen, Peter K PK; Reynolds, Richard J RJ; Wasko, Mary Chester MC; Oeser, Anette A; Chung, Cecilia P CP; Stein, C Michael CM; Giles, Jon T JT; Bathon, Joan M JM
Susceptibility Loci for Clinical Coronary Artery Disease and Subclinical Coronary Atherosclerosis Throughout the Life-Course.
Circulation. Cardiovascular Genetics
Salfati, Elias E; Nandkeolyar, Shuktika S; Fortmann, Stephen P SP; Sidney, Stephen S; Hlatky, Mark A MA; Quertermous, Thomas T; Go, Alan S AS; Iribarren, Carlos C; Herrington, David M DM; Goldstein, Benjamin A BA; Assimes, Themistocles L TL
Lipids, obesity and gallbladder disease in women: insights from genetic studies using the cardiovascular gene-centric 50K SNP array.
European Journal Of Human Genetics : Ejhg
Rodriguez, Santiago S; Gaunt, Tom R TR; Guo, Yiran Y; Zheng, Jie J; Barnes, Michael R MR; Tang, Weihang W; Danish, Fazal F; Johnson, Andrew A; Castillo, Berta A BA; Li, Yun R YR; Hakonarson, Hakon H; Buxbaum, Sarah G SG; Palmer, Tom T; Tsai, Michael Y MY; Lange, Leslie A LA; Ebrahim, Shah S; Davey Smith, George G; Lawlor, Debbie A DA; Folsom, Aaron R AR; Hoogeveen, Ron R; Reiner, Alex A; Keating, Brendan B; Day, Ian N M IN
Would raising the total cholesterol diagnostic cut-off from 7.5 mmol/L to 9.3 mmol/L improve detection rate of patients with monogenic familial hypercholesterolaemia?
Atherosclerosis
Futema, M M; Kumari, M M; Boustred, C C; Kivimaki, M M; Humphries, S E SE
Prospective associations of coronary heart disease loci in African Americans using the MetaboChip: the PAGE study.
Plos One
Franceschini, Nora N; Hu, Yijuan Y; Reiner, Alex P AP; Buyske, Steven S; Nalls, Mike M; Yanek, Lisa R LR; Li, Yun Y; Hindorff, Lucia A LA; Cole, Shelley A SA; Howard, Barbara V BV; Stafford, Jeanette M JM; Carty, Cara L CL; Sethupathy, Praveen P; Martin, Lisa W LW; Lin, Dan-Yu DY; Johnson, Karen C KC; Becker, Lewis C LC; North, Kari E KE; Dehghan, Abbas A; Bis, Joshua C JC; Liu, Yongmei Y; Greenland, Philip P; Manson, JoAnn E JE; Maeda, Nobuyo N; Garcia, Melissa M; Harris, Tamara B TB; Becker, Diane M DM; O'Donnell, Christopher C; Heiss, Gerardo G; Kooperberg, Charles C; Boerwinkle, Eric E
Refinement of variant selection for the LDL cholesterol genetic risk score in the diagnosis of the polygenic form of clinical familial hypercholesterolemia and replication in samples from 6 countries.
Clinical Chemistry
Futema, Marta M; Shah, Sonia S; Cooper, Jackie A JA; Li, KaWah K; Whittall, Ros A RA; Sharifi, Mahtab M; Goldberg, Olivia O; Drogari, Euridiki E; Mollaki, Vasiliki V; Wiegman, Albert A; Defesche, Joep J; D'Agostino, Maria N MN; D'Angelo, Antonietta A; Rubba, Paolo P; Fortunato, Giuliana G; Waluś-Miarka, Małgorzata M; Hegele, Robert A RA; Aderayo Bamimore, Mary M; Durst, Ronen R; Leitersdorf, Eran E; Mulder, Monique T MT; Roeters van Lennep, Jeanine E JE; Sijbrands, Eric J G EJ; Whittaker, John C JC; Talmud, Philippa J PJ; Humphries, Steve E SE
Extension of GWAS results for lipid-related phenotypes to extreme obesity using electronic health record (EHR) data and the Metabochip.
Frontiers In Genetics
Parihar, Ankita A; Wood, G Craig GC; Chu, Xin X; Jin, Qunjan Q; Argyropoulos, George G; Still, Christopher D CD; Shuldiner, Alan R AR; Mitchell, Braxton D BD; Gerhard, Glenn S GS
Whole exome sequencing of familial hypercholesterolaemia patients negative for LDLR/APOB/PCSK9 mutations.
Journal Of Medical Genetics
Futema, Marta M; Plagnol, Vincent V; Li, KaWah K; Whittall, Ros A RA; Neil, H Andrew W HA; Seed, Mary M; , ; Bertolini, Stefano S; Calandra, Sebastiano S; Descamps, Olivier S OS; Graham, Colin A CA; Hegele, Robert A RA; Karpe, Fredrik F; Durst, Ronen R; Leitersdorf, Eran E; Lench, Nicholas N; Nair, Devaki R DR; Soran, Handrean H; Van Bockxmeer, Frank M FM; , ; Humphries, Steve E SE
Multiancestral analysis of inflammation-related genetic variants and C-reactive protein in the population architecture using genomics and epidemiology study.
Circulation. Cardiovascular Genetics
Kocarnik, Jonathan M JM; Pendergrass, Sarah A SA; Carty, Cara L CL; Pankow, James S JS; Schumacher, Fredrick R FR; Cheng, Iona I; Durda, Peter P; Ambite, José Luis JL; Deelman, Ewa E; Cook, Nancy R NR; Liu, Simin S; Wactawski-Wende, Jean J; Hutter, Carolyn C; Brown-Gentry, Kristin K; Wilson, Sarah S; Best, Lyle G LG; Pankratz, Nathan N; Hong, Ching-Ping CP; Cole, Shelley A SA; Voruganti, V Saroja VS; Bůžkova, Petra P; Jorgensen, Neal W NW; Jenny, Nancy S NS; Wilkens, Lynne R LR; Haiman, Christopher A CA; Kolonel, Laurence N LN; Lacroix, Andrea A; North, Kari K; Jackson, Rebecca R; Le Marchand, Loic L; Hindorff, Lucia A LA; Crawford, Dana C DC; Gross, Myron M; Peters, Ulrike U
Heart disease and stroke statistics--2014 update: a report from the American Heart Association.
Circulation
Go, Alan S AS; Mozaffarian, Dariush D; Roger, Véronique L VL; Benjamin, Emelia J EJ; Berry, Jarett D JD; Blaha, Michael J MJ; Dai, Shifan S; Ford, Earl S ES; Fox, Caroline S CS; Franco, Sheila S; Fullerton, Heather J HJ; Gillespie, Cathleen C; Hailpern, Susan M SM; Heit, John A JA; Howard, Virginia J VJ; Huffman, Mark D MD; Judd, Suzanne E SE; Kissela, Brett M BM; Kittner, Steven J SJ; Lackland, Daniel T DT; Lichtman, Judith H JH; Lisabeth, Lynda D LD; Mackey, Rachel H RH; Magid, David J DJ; Marcus, Gregory M GM; Marelli, Ariane A; Matchar, David B DB; McGuire, Darren K DK; Mohler, Emile R ER; Moy, Claudia S CS; Mussolino, Michael E ME; Neumar, Robert W RW; Nichol, Graham G; Pandey, Dilip K DK; Paynter, Nina P NP; Reeves, Matthew J MJ; Sorlie, Paul D PD; Stein, Joel J; Towfighi, Amytis A; Turan, Tanya N TN; Virani, Salim S SS; Wong, Nathan D ND; Woo, Daniel D; Turner, Melanie B MB; ,
Lipid trait-associated genetic variation is associated with gallstone disease in the diverse Third National Health and Nutrition Examination Survey (NHANES III).
Bmc Medical Genetics
Goodloe, Robert R; Brown-Gentry, Kristin K; Gillani, Niloufar B NB; Jin, Hailing H; Mayo, Ping P; Allen, Melissa M; McClellan, Bob B; Boston, Jonathan J; Sutcliffe, Cara C; Schnetz-Boutaud, Nathalie N; Dilks, Holli H HH; Crawford, Dana C DC
Common genetic variants do not associate with CAD in familial hypercholesterolemia.
European Journal Of Human Genetics : Ejhg
van Iperen, Erik P A EP; Sivapalaratnam, Suthesh S; Boekholdt, S Matthijs SM; Hovingh, G Kees GK; Maiwald, Stephanie S; Tanck, Michael W MW; Soranzo, Nicole N; Stephens, Jonathan C JC; Sambrook, Jennifer G JG; Levi, Marcel M; Ouwehand, Willem H WH; Kastelein, John Jp JJ; Trip, Mieke D MD; Zwinderman, Aeilko H AH
Non-cholesterol sterol levels predict hyperglycemia and conversion to type 2 diabetes in Finnish men.
Plos One
Cederberg, Henna H; Gylling, Helena H; Miettinen, Tatu A TA; Paananen, Jussi J; Vangipurapu, Jagadish J; Pihlajamäki, Jussi J; Kuulasmaa, Teemu T; Stančáková, Alena A; Smith, Ulf U; Kuusisto, Johanna J; Laakso, Markku M
Shared ancestral susceptibility to colorectal cancer and other nutrition related diseases.
Bmc Medical Genetics
Huhn, Stefanie S; Bevier, Melanie M; Rudolph, Anja A; Pardini, Barbara B; Naccarati, Alessio A; Hein, Rebecca R; Hoffmeister, Michael M; Vodickova, Ludmila L; Novotny, Jan J; Brenner, Hermann H; Chang-Claude, Jenny J; Hemminki, Kari K; Vodicka, Pavel P; Försti, Asta A
Plasma HDL cholesterol and risk of myocardial infarction: a mendelian randomisation study.
Lancet (London, England)
Voight, Benjamin F BF; Peloso, Gina M GM; Orho-Melander, Marju M; Frikke-Schmidt, Ruth R; Barbalic, Maja M; Jensen, Majken K MK; Hindy, George G; Hólm, Hilma H; Ding, Eric L EL; Johnson, Toby T; Schunkert, Heribert H; Samani, Nilesh J NJ; Clarke, Robert R; Hopewell, Jemma C JC; Thompson, John F JF; Li, Mingyao M; Thorleifsson, Gudmar G; Newton-Cheh, Christopher C; Musunuru, Kiran K; Pirruccello, James P JP; Saleheen, Danish D; Chen, Li L; Stewart, Alexandre F R A; Schillert, Arne A; Thorsteinsdottir, Unnur U; Thorgeirsson, Gudmundur G; Anand, Sonia S; Engert, James C JC; Morgan, Thomas T; Spertus, John J; Stoll, Monika M; Berger, Klaus K; Martinelli, Nicola N; Girelli, Domenico D; McKeown, Pascal P PP; Patterson, Christopher C CC; Epstein, Stephen E SE; Devaney, Joseph J; Burnett, Mary-Susan MS; Mooser, Vincent V; Ripatti, Samuli S; Surakka, Ida I; Nieminen, Markku S MS; Sinisalo, Juha J; Lokki, Marja-Liisa ML; Perola, Markus M; Havulinna, Aki A; de Faire, Ulf U; Gigante, Bruna B; Ingelsson, Erik E; Zeller, Tanja T; Wild, Philipp P; de Bakker, Paul I W PI; Klungel, Olaf H OH; Maitland-van der Zee, Anke-Hilse AH; Peters, Bas J M BJ; de Boer, Anthonius A; Grobbee, Diederick E DE; Kamphuisen, Pieter W PW; Deneer, Vera H M VH; Elbers, Clara C CC; Onland-Moret, N Charlotte NC; Hofker, Marten H MH; Wijmenga, Cisca C; Verschuren, W M Monique WM; Boer, Jolanda M A JM; van der Schouw, Yvonne T YT; Rasheed, Asif A; Frossard, Philippe P; Demissie, Serkalem S; Willer, Cristen C; Do, Ron R; Ordovas, Jose M JM; Abecasis, Gonçalo R GR; Boehnke, Michael M; Mohlke, Karen L KL; Daly, Mark J MJ; Guiducci, Candace C; Burtt, Noël P NP; Surti, Aarti A; Gonzalez, Elena E; Purcell, Shaun S; Gabriel, Stacey S; Marrugat, Jaume J; Peden, John J; Erdmann, Jeanette J; Diemert, Patrick P; Willenborg, Christina C; König, Inke R IR; Fischer, Marcus M; Hengstenberg, Christian C; Ziegler, Andreas A; Buysschaert, Ian I; Lambrechts, Diether D; Van de Werf, Frans F; Fox, Keith A KA; El Mokhtari, Nour Eddine NE; Rubin, Diana D; Schrezenmeir, Jürgen J; Schreiber, Stefan S; Schäfer, Arne A; Danesh, John J; Blankenberg, Stefan S; Roberts, Robert R; McPherson, Ruth R; Watkins, Hugh H; Hall, Alistair S AS; Overvad, Kim K; Rimm, Eric E; Boerwinkle, Eric E; Tybjaerg-Hansen, Anne A; Cupples, L Adrienne LA; Reilly, Muredach P MP; Melander, Olle O; Mannucci, Pier M PM; Ardissino, Diego D; Siscovick, David D; Elosua, Roberto R; Stefansson, Kari K; O'Donnell, Christopher J CJ; Salomaa, Veikko V; Rader, Daniel J DJ; Peltonen, Leena L; Schwartz, Stephen M SM; Altshuler, David D; Kathiresan, Sekar S
Associations between incident ischemic stroke events and stroke and cardiovascular disease-related genome-wide association studies single nucleotide polymorphisms in the Population Architecture Using Genomics and Epidemiology study.
Circulation. Cardiovascular Genetics
Carty, Cara L CL; Buzková, Petra P; Fornage, Myriam M; Franceschini, Nora N; Cole, Shelley S; Heiss, Gerardo G; Hindorff, Lucia A LA; Howard, Barbara V BV; Mann, Sue S; Martin, Lisa W LW; Zhang, Ying Y; Matise, Tara C TC; Prentice, Ross R; Reiner, Alexander P AP; Kooperberg, Charles C
The Next PAGE in understanding complex traits: design for the analysis of Population Architecture Using Genetics and Epidemiology (PAGE) Study.
American Journal Of Epidemiology
Matise, Tara C TC; Ambite, Jose Luis JL; Buyske, Steven S; Carlson, Christopher S CS; Cole, Shelley A SA; Crawford, Dana C DC; Haiman, Christopher A CA; Heiss, Gerardo G; Kooperberg, Charles C; Marchand, Loic Le LL; Manolio, Teri A TA; North, Kari E KE; Peters, Ulrike U; Ritchie, Marylyn D MD; Hindorff, Lucia A LA; Haines, Jonathan L JL; ,
Genetic determinants of lipid traits in diverse populations from the population architecture using genomics and epidemiology (PAGE) study.
Plos Genetics
Dumitrescu, Logan L; Carty, Cara L CL; Taylor, Kira K; Schumacher, Fredrick R FR; Hindorff, Lucia A LA; Ambite, José L JL; Anderson, Garnet G; Best, Lyle G LG; Brown-Gentry, Kristin K; Bůžková, Petra P; Carlson, Christopher S CS; Cochran, Barbara B; Cole, Shelley A SA; Devereux, Richard B RB; Duggan, Dave D; Eaton, Charles B CB; Fornage, Myriam M; Franceschini, Nora N; Haessler, Jeff J; Howard, Barbara V BV; Johnson, Karen C KC; Laston, Sandra S; Kolonel, Laurence N LN; Lee, Elisa T ET; MacCluer, Jean W JW; Manolio, Teri A TA; Pendergrass, Sarah A SA; Quibrera, Miguel M; Shohet, Ralph V RV; Wilkens, Lynne R LR; Haiman, Christopher A CA; Le Marchand, Loïc L; Buyske, Steven S; Kooperberg, Charles C; North, Kari E KE; Crawford, Dana C DC
Association of common DNA sequence variants at 33 genetic loci with blood lipids in individuals of African ancestry from Jamaica.
Human Genetics
Gupta, R R; Ejebe, K K; Butler, J J; Lettre, G G; Lyon, H H; Guiducci, C C; Wilks, R R; Bennett, F F; Forrester, T T; Tayo, B B; Musunuru, K K; Hirschhorn, J J; Kathiresan, S S; Cooper, R S RS; McKenzie, C A CA
Analysis of recently identified dyslipidemia alleles reveals two loci that contribute to risk for carotid artery disease.
Lipids In Health And Disease
Ronald, James J; Rajagopalan, Ramakrishnan R; Ranchalis, Jane E JE; Marshall, Julieann K JK; Hatsukami, Thomas S TS; Heagerty, Patrick J PJ; Jarvik, Gail P GP
Gene-centric association signals for lipids and apolipoproteins identified via the HumanCVD BeadChip.
American Journal Of Human Genetics
Talmud, Philippa J PJ; Drenos, Fotios F; Shah, Sonia S; Shah, Tina T; Palmen, Jutta J; Verzilli, Claudio C; Gaunt, Tom R TR; Pallas, Jacky J; Lovering, Ruth R; Li, Kawah K; Casas, Juan Pablo JP; Sofat, Reecha R; Kumari, Meena M; Rodriguez, Santiago S; Johnson, Toby T; Newhouse, Stephen J SJ; Dominiczak, Anna A; Samani, Nilesh J NJ; Caulfield, Mark M; Sever, Peter P; Stanton, Alice A; Shields, Denis C DC; Padmanabhan, Sandosh S; Melander, Olle O; Hastie, Claire C; Delles, Christian C; Ebrahim, Shah S; Marmot, Michael G MG; Smith, George Davey GD; Lawlor, Debbie A DA; Munroe, Patricia B PB; Day, Ian N IN; Kivimaki, Mika M; Whittaker, John J; Humphries, Steve E SE; Hingorani, Aroon D AD; , ; , ; ,
Common variants at 30 loci contribute to polygenic dyslipidemia.
Nature Genetics
Kathiresan, Sekar S; Willer, Cristen J CJ; Peloso, Gina M GM; Demissie, Serkalem S; Musunuru, Kiran K; Schadt, Eric E EE; Kaplan, Lee L; Bennett, Derrick D; Li, Yun Y; Tanaka, Toshiko T; Voight, Benjamin F BF; Bonnycastle, Lori L LL; Jackson, Anne U AU; Crawford, Gabriel G; Surti, Aarti A; Guiducci, Candace C; Burtt, Noel P NP; Parish, Sarah S; Clarke, Robert R; Zelenika, Diana D; Kubalanza, Kari A KA; Morken, Mario A MA; Scott, Laura J LJ; Stringham, Heather M HM; Galan, Pilar P; Swift, Amy J AJ; Kuusisto, Johanna J; Bergman, Richard N RN; Sundvall, Jouko J; Laakso, Markku M; Ferrucci, Luigi L; Scheet, Paul P; Sanna, Serena S; Uda, Manuela M; Yang, Qiong Q; Lunetta, Kathryn L KL; Dupuis, Josée J; de Bakker, Paul I W PI; O'Donnell, Christopher J CJ; Chambers, John C JC; Kooner, Jaspal S JS; Hercberg, Serge S; Meneton, Pierre P; Lakatta, Edward G EG; Scuteri, Angelo A; Schlessinger, David D; Tuomilehto, Jaakko J; Collins, Francis S FS; Groop, Leif L; Altshuler, David D; Collins, Rory R; Lathrop, G Mark GM; Melander, Olle O; Salomaa, Veikko V; Peltonen, Leena L; Orho-Melander, Marju M; Ordovas, Jose M JM; Boehnke, Michael M; Abecasis, Gonçalo R GR; Mohlke, Karen L KL; Cupples, L Adrienne LA