Quantifying prediction of pathogenicity for within-codon concordance (PM5) using 7541 functional classifications of BRCA1 and MSH2 missense variants.
Genetics In Medicine : Official Journal Of The American College Of Medical Genetics
Loong, Lucy L; Cubuk, Cankut C; Choi, Subin S; Allen, Sophie S; Torr, Beth B; Garrett, Alice A; Loveday, Chey C; Durkie, Miranda M; Callaway, Alison A; Burghel, George J GJ; Drummond, James J; Robinson, Rachel R; Berry, Ian R IR; Wallace, Andrew A; Eccles, Diana M DM; Tischkowitz, Marc M; Ellard, Sian S; Ware, James S JS; Hanson, Helen H; Turnbull, Clare C; ,
Publication Date: 2022-03
Variant appearance in text: MSH2: 416A>G; Asn139Ser
Mutations in SETD2 and genes affecting histone H3K36 methylation target hemispheric high-grade gliomas.
Acta Neuropathologica
Fontebasso, Adam M AM; Schwartzentruber, Jeremy J; Khuong-Quang, Dong-Anh DA; Liu, Xiao-Yang XY; Sturm, Dominik D; Korshunov, Andrey A; Jones, David T W DT; Witt, Hendrik H; Kool, Marcel M; Albrecht, Steffen S; Fleming, Adam A; Hadjadj, Djihad D; Busche, Stephan S; Lepage, Pierre P; Montpetit, Alexandre A; Staffa, Alfredo A; Gerges, Noha N; Zakrzewska, Magdalena M; Zakrzewski, Krzystof K; Liberski, Pawel P PP; Hauser, Peter P; Garami, Miklos M; Klekner, Almos A; Bognar, Laszlo L; Zadeh, Gelareh G; Faury, Damien D; Pfister, Stefan M SM; Jabado, Nada N; Majewski, Jacek J
Colon cancer associated genes exhibit signatures of positive selection at functionally significant positions.
Bmc Evolutionary Biology
Morgan, Claire C CC; Shakya, Kabita K; Webb, Andrew A; Walsh, Thomas A TA; Lynch, Mark M; Loscher, Christine E CE; Ruskin, Heather J HJ; O'Connell, Mary J MJ