MSH6 c.2021G>C ;(p.G674A)

Variant ID: 2-48027143-G-C

NM_000179.2(MSH6):c.2021G>C;(p.G674A)

This variant was identified in 5 publications

View GRCh38 version.



Variant-Specific Resource Links:
gnomAD v2.1.1
Mutalizer Name Checker
Google
UCSC Genome Browser
ClinVar
dbSNP

Publications:

Mispair-bound human MutS-MutL complex triggers DNA incisions and activates mismatch repair.

Cell Research
Ortega, Janice J; Lee, Grace Sanghee GS; Gu, Liya L; Yang, Wei W; Li, Guo-Min GM
Publication Date: 2021-05

Variant appearance in text: MSH6: G674A
PubMed Link: 33510387
Variant Present in the following documents:
  • 41422_2021_Article_468.pdf
View BVdb publication page


Mispair-bound human MutS-MutL complex triggers DNA incisions and activates mismatch repair.

Cell Research
Ortega, Janice J; Lee, Grace Sanghee GS; Gu, Liya L; Yang, Wei W; Li, Guo-Min GM
Publication Date: 2021-05

Variant appearance in text: MSH6: G674A
PubMed Link: 33510387
Variant Present in the following documents:
  • 41422_2021_Article_468.pdf
View BVdb publication page


Manipulation of DNA Repair Proficiency in Mouse Models of Colorectal Cancer.

Biomed Research International
Mcilhatton, Michael A MA; Boivin, Gregory P GP; Groden, Joanna J
Publication Date: 2016

Variant appearance in text: MSH6: G674A
PubMed Link: 27413734
Variant Present in the following documents:
  • Main text
  • BMRI2016-1414383.pdf
View BVdb publication page


Antibody diversification caused by disrupted mismatch repair and promiscuous DNA polymerases.

Dna Repair
Zanotti, Kimberly J KJ; Gearhart, Patricia J PJ
Publication Date: 2016-02

Variant appearance in text: MSH6: G674A
PubMed Link: 26719140
Variant Present in the following documents:
  • Main text
View BVdb publication page


Mouse models of DNA mismatch repair in cancer research.

Dna Repair
Lee, Kyeryoung K; Tosti, Elena E; Edelmann, Winfried W
Publication Date: 2016-02

Variant appearance in text: MSH6: G674A
PubMed Link: 26708047
Variant Present in the following documents:
  • Main text
View BVdb publication page


The dual nature of mismatch repair as antimutator and mutator: for better or for worse.

Frontiers In Genetics
Bak, Sara Thornby ST; Sakellariou, Despoina D; Pena-Diaz, Javier J
Publication Date: 2014

Variant appearance in text: MSH6: G674A
PubMed Link: 25191341
Variant Present in the following documents:
  • fgene-05-00287.pdf
View BVdb publication page