Publications:

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A new age in understanding adult hippocampal neurogenesis in Alzheimer's disease.

Neural Regeneration Research

Hanspal, Maya A MA; Gillotin, Sébastien S

Publication Date: 2022-12

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PubMed Link: 35662190

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• Main text
• NRR-17-2615.pdf

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Mapping the genetic landscape of early-onset Alzheimer's disease in a cohort of 36 families.

Alzheimer'S Research & Therapy

Mol, Merel O MO; van der Lee, Sven J SJ; Hulsman, Marc M; Pijnenburg, Yolande A L YAL; Scheltens, Phillip P; , ; Seelaar, Harro H; van Swieten, John C JC; Kaat, Laura Donker LD; Holstege, Henne H; van Rooij, Jeroen G J JGJ

Publication Date: 2022-06-01

Variant appearance in text: APP: V717I

PubMed Link: 35650585

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• Main text
• 13195_2022_Article_1018.pdf

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Impact of IL-21-associated peripheral and brain crosstalk on the Alzheimer's disease neuropathology.

Cellular And Molecular Life Sciences : Cmls

Agrawal, Sudhanshu S; Baulch, Janet E JE; Madan, Shreya S; Salah, Seher S; Cheeks, Samantha N SN; Krattli, Robert P RP; Subramanian, Veedamali S VS; Acharya, Munjal M MM; Agrawal, Anshu A

Publication Date: 2022-06-01

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PubMed Link: 35648273

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• Main text
• 18_2022_Article_4347.pdf

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Altered Blood and Brain Expression of Inflammation and Redox Genes in Alzheimer's Disease, Common to APPV717I × TAUP301L Mice and Patients.

International Journal Of Molecular Sciences

Cucos, Catalina Anca CA; Milanesi, Elena E; Dobre, Maria M; Musat, Ioana Andreea IA; Manda, Gina G; Cuadrado, Antonio A

Publication Date: 2022-05-21

Variant appearance in text: APP: V717I

PubMed Link: 35628609

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• Main text

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Transgenic Mouse Models of Alzheimer's Disease: An Integrative Analysis.

International Journal Of Molecular Sciences

Sanchez-Varo, Raquel R; Mejias-Ortega, Marina M; Fernandez-Valenzuela, Juan Jose JJ; Nuñez-Diaz, Cristina C; Caceres-Palomo, Laura L; Vegas-Gomez, Laura L; Sanchez-Mejias, Elisabeth E; Trujillo-Estrada, Laura L; Garcia-Leon, Juan Antonio JA; Moreno-Gonzalez, Ines I; Vizuete, Marisa M; Vitorica, Javier J; Baglietto-Vargas, David D; Gutierrez, Antonia A

Publication Date: 2022-05-12

Variant appearance in text: APP: V717I

PubMed Link: 35628216

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• Main text
• ijms-23-05404.pdf

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Olfactory Evaluation in Alzheimer's Disease Model Mice.

Brain Sciences

Zhang, Jingjing J; Zhao, Zixuan Z; Sun, Siqi S; Li, Jing J; Wang, Yu Y; Dong, Jingyin J; Yang, Su S; Lou, Yiyi Y; Yang, Jing J; Li, Weiyun W; Li, Shanshan S

Publication Date: 2022-05-06

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PubMed Link: 35624994

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• Main text
• brainsci-12-00607.pdf

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Advances in Recapitulating Alzheimer's Disease Phenotypes Using Human Induced Pluripotent Stem Cell-Based In Vitro Models.

Brain Sciences

Hasan, Md Fayad MF; Trushina, Eugenia E

Publication Date: 2022-04-26

Variant appearance in text: APP: V717I

PubMed Link: 35624938

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• Main text
• brainsci-12-00552.pdf

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NeuroProtect, a Candidate Formula From Traditional Chinese Medicine, Attenuates Amyloid-β and Restores Synaptic Structures in APP/PS1 Transgenic Mice.

Frontiers In Pharmacology

Tan, Yan Y; Wang, Xu X; Zhang, Jiani J; Zhang, Huawei H; Li, Haiyan H; Peng, Tiantian T; Chen, Weihang W; Wei, Peng P; Liu, Zhaoheng Z; He, Fang F; Li, Jiao J; Ding, Haimin H; Li, Na N; Wang, Zhaoyang Z; Zhang, Zhenqiang Z; Hua, Qian Q

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35586051

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• fphar-13-850175.pdf

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Age-Dependent Alterations of Cognition, Mitochondrial Function, and Beta-Amyloid Deposition in a Murine Model of Alzheimer's Disease-A Longitudinal Study.

Frontiers In Aging Neuroscience

Reutzel, Martina M; Grewal, Rekha R; Joppe, Aljoscha A; Eckert, Gunter P GP

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35585868

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• fnagi-14-875989.pdf

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Glatiramer Acetate Immunomodulation: Evidence of Neuroprotection and Cognitive Preservation.

Cells

Kasindi, Arielle A; Fuchs, Dieu-Trang DT; Koronyo, Yosef Y; Rentsendorj, Altan A; Black, Keith L KL; Koronyo-Hamaoui, Maya M

Publication Date: 2022-05-07

Variant appearance in text: APP: V717I

PubMed Link: 35563884

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• cells-11-01578.pdf

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Impact of Cerebral Amyloid Angiopathy in Two Transgenic Mouse Models of Cerebral β-Amyloidosis: A Neuropathological Study.

International Journal Of Molecular Sciences

Marazuela, Paula P; Paez-Montserrat, Berta B; Bonaterra-Pastra, Anna A; Solé, Montse M; Hernández-Guillamon, Mar M

Publication Date: 2022-04-29

Variant appearance in text: APP: V717I

PubMed Link: 35563362

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• ijms-23-04972.pdf

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High-Resolution Digital Panorama of Multiple Structures in Whole Brain of Alzheimer's Disease Mice.

Frontiers In Neuroscience

Yin, Xianzhen X; Zhang, Xiaochuan X; Zhang, Jingjing J; Yang, Weicheng W; Sun, Xian X; Zhang, Haiyan H; Gao, Zhaobing Z; Jiang, Hualiang H

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35516801

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• fnins-16-870520.pdf

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GPCR19 Regulates P2X7R-Mediated NLRP3 Inflammasomal Activation of Microglia by Amyloid β in a Mouse Model of Alzheimer's Disease.

Frontiers In Immunology

Islam, Jahirul J; Cho, Jung-Ah JA; Kim, Ju-Yong JY; Park, Kyung-Sun KS; Koh, Young-Jae YJ; Chung, Chu Young CY; Lee, Eun-Jae EJ; Nam, Soo Jeong SJ; Lee, Kyoungyul K; Kim, Seoung-Heon SH; Park, Sung-Hye SH; Lee, Dong Young DY; Kim, Byeong C BC; Lee, Kyung-Hwa KH; Seong, Seung-Yong SY

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35464490

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• fimmu-13-766919.pdf

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Cellular Reprogramming and Its Potential Application in Alzheimer's Disease.

Frontiers In Neuroscience

Zhou, Chao C; Ni, Wanyan W; Zhu, Taiyang T; Dong, Shuyu S; Sun, Ping P; Hua, Fang F

Publication Date: 2022

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PubMed Link: 35464309

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• fnins-16-884667.pdf

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Panax Notoginseng Saponin Rg1 Can Effectively Improve the Cognitive Function of 5 × FAD Mice.

Journal Of Healthcare Engineering

Guo, Lili L; Li, Kun K; Zhou, Jiajun J; Luo, Lian L

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35449867

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• JHE2022-5152761.pdf

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Recent Advances in the Modeling of Alzheimer's Disease.

Frontiers In Neuroscience

Sasaguri, Hiroki H; Hashimoto, Shoko S; Watamura, Naoto N; Sato, Kaori K; Takamura, Risa R; Nagata, Kenichi K; Tsubuki, Satoshi S; Ohshima, Toshio T; Yoshiki, Atsushi A; Sato, Kenya K; Kumita, Wakako W; Sasaki, Erika E; Kitazume, Shinobu S; Nilsson, Per P; Winblad, Bengt B; Saito, Takashi T; Iwata, Nobuhisa N; Saido, Takaomi C TC

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35431779

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• fnins-16-807473.pdf

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Are transient protein-protein interactions more dispensable?

Plos Computational Biology

Ghadie, Mohamed Ali MA; Xia, Yu Y

Publication Date: 2022-04

Variant appearance in text: APP: 2149G>A; Val717Ile

PubMed Link: 35404956

Variant Present in the following documents:

• pcbi.1010013.s002.xlsx

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AGE-TXNIP axis drives inflammation in Alzheimer's by targeting Aβ to mitochondria in microglia.

Cell Death & Disease

Sbai, Oualid O; Djelloul, Mehdi M; Auletta, Antonia A; Ieraci, Alessandro A; Vascotto, Carlo C; Perrone, L L

Publication Date: 2022-04-04

Variant appearance in text: APP: V717I

PubMed Link: 35379773

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• 41419_2022_4758_MOESM1_ESM.pdf

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The Multifaceted Neurotoxicity of Astrocytes in Ageing and Age-Related Neurodegenerative Diseases: A Translational Perspective.

Frontiers In Physiology

Bouvier, David S DS; Fixemer, Sonja S; Heurtaux, Tony T; Jeannelle, Félicia F; Frauenknecht, Katrin B M KBM; Mittelbronn, Michel M

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35370777

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• fphys-13-814889.pdf

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miR-200c suppression increases tau hyperphosphorylation by targeting 14-3-3γ in early stage of 5xFAD mouse model of Alzheimer's disease.

International Journal Of Biological Sciences

Park, Hyunjun H; Lee, Yeong-Bae YB; Chang, Keun-A KA

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35342350

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• ijbsv18p2220.pdf

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Effects of subchronic dietary exposure to the engineered nanomaterials SiO2 and CeO2 in C57BL/6J and 5xFAD Alzheimer model mice.

Particle And Fibre Toxicology

Sofranko, Adriana A; Wahle, Tina T; Kolling, Julia J; Heusinkveld, Harm J HJ; Stahlmecke, Burkhard B; Rosenbruch, Martin M; Albrecht, Catrin C; Schins, Roel P F RPF

Publication Date: 2022-03-25

Variant appearance in text: APP: V717I

PubMed Link: 35337343

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• 12989_2022_Article_461.pdf

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Amelioration of Experimental Autoimmune Encephalomyelitis in Alzheimer's Disease Mouse Models: A Potential Role for Aβ.

Cells

Shi, Changjie C; Cha, Jiaxue J; Gong, Junyuan J; Wang, Shaodeng S; Zeng, Peng P; Lian, Junjiang J; Zhang, Bowen B; Hua, Qiuhong Q; Lv, Jie J; Du, Changsheng C; Xie, Xin X; Zhang, Ru R

Publication Date: 2022-03-16

Variant appearance in text: APP: V717I

PubMed Link: 35326455

Variant Present in the following documents:

• cells-11-01004.pdf

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Theranostic F-SLOH mitigates Alzheimer's disease pathology involving TFEB and ameliorates cognitive functions in Alzheimer's disease models.

Redox Biology

Iyaswamy, Ashok A; Wang, Xueli X; Krishnamoorthi, Senthilkumar S; Kaliamoorthy, Venkatapathy V; Sreenivasmurthy, Sravan G SG; Kumar Durairajan, Siva Sundara SS; Song, Ju-Xian JX; Tong, Benjamin Chun-Kit BC; Zhu, Zhou Z; Su, Cheng-Fu CF; Liu, Jia J; Cheung, King-Ho KH; Lu, Jia-Hong JH; Tan, Jie-Qiong JQ; Li, Hung Wing HW; Wong, Man Shing MS; Li, Min M

Publication Date: 2022-03-08

Variant appearance in text: APP: V717I

PubMed Link: 35286997

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• main.pdf

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Increased MYD88 blood transcript in a mouse model of Alzheimer's disease.

Bmc Neuroscience

Cucos, Catalina Anca CA; Dobre, Maria M; Dragnea, Elena Mihaela EM; Manda, Gina G; Milanesi, Elena E

Publication Date: 2022-03-11

Variant appearance in text: APP: V717I

PubMed Link: 35277123

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• 12868_2022_Article_699.pdf

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The Cardiac Dysfunction Caused by Metabolic Alterations in Alzheimer's Disease.

Frontiers In Cardiovascular Medicine

Murphy, Jiayuan J; Le, Tran Ngoc Van TNV; Fedorova, Julia J; Yang, Yi Y; Krause-Hauch, Meredith M; Davitt, Kayla K; Zoungrana, Linda Ines LI; Fatmi, Mohammad Kasim MK; Lesnefsky, Edward J EJ; Li, Ji J; Ren, Di D

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35274014

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• fcvm-09-850538.pdf

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Failure of Alzheimer's Mice Brain Resident Neural Precursor Cells in Supporting Microglia-Mediated Amyloid β Clearance.

Cells

Lachish, Marva M; Fainstein, Nina N; Ganz, Tal T; Sofer, Lihi L; Ben-Hur, Tamir T

Publication Date: 2022-03-03

Variant appearance in text: APP: V717I

PubMed Link: 35269501

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• cells-11-00876.pdf

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Unraveling pathological mechanisms in neurological disorders: the impact of cell-based and organoid models.

Neural Regeneration Research

Langlie, Jake J; Mittal, Rahul R; Finberg, Ariel A; Bencie, Nathalie B NB; Mittal, Jeenu J; Omidian, Hossein H; Omidi, Yadollah Y; Eshraghi, Adrien A AA

Publication Date: 2022-10

Variant appearance in text: APP: V717I

PubMed Link: 35259819

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• NRR-17-2131.pdf

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A Mutant Variant of E2F4 Triggers Multifactorial Therapeutic Effects in 5xFAD Mice.

Molecular Neurobiology

López-Sánchez, Noelia N; Ramón-Landreau, Morgan M; Trujillo, Cristina C; Garrido-García, Alberto A; Frade, José M JM

Publication Date: 2022-03-07

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PubMed Link: 35254651

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• 12035_2022_Article_2764.pdf

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Emerging Electroencephalographic Biomarkers to Improve Preclinical to Clinical Translation in Alzheimer's Disease.

Frontiers In Aging Neuroscience

Cope, Zackary A ZA; Murai, Takeshi T; Sukoff Rizzo, Stacey J SJ

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35250541

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• fnagi-14-805063.pdf

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Microglial VPS35 deficiency impairs Aβ phagocytosis and Aβ-induced disease-associated microglia, and enhances Aβ associated pathology.

Journal Of Neuroinflammation

Ren, Xiao X; Yao, Lingling L; Wang, YongGang Y; Mei, Lin L; Xiong, Wen-Cheng WC

Publication Date: 2022-03-02

Variant appearance in text: APP: V717I

PubMed Link: 35236374

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• 12974_2022_Article_2422.pdf

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Meprin β knockout reduces brain Aβ levels and rescues learning and memory impairments in the APP/lon mouse model for Alzheimer's disease.

Cellular And Molecular Life Sciences : Cmls

Marengo, Liana L; Armbrust, Fred F; Schoenherr, Caroline C; Storck, Steffen E SE; Schmitt, Ulrich U; Zampar, Silvia S; Wirths, Oliver O; Altmeppen, Hermann H; Glatzel, Markus M; Kaether, Christoph C; Weggen, Sascha S; Becker-Pauly, Christoph C; Pietrzik, Claus U CU

Publication Date: 2022-03-02

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PubMed Link: 35235058

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• 18_2022_Article_4205.pdf

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Hippocampal neurogenesis and pro-neurogenic therapies for Alzheimer's disease.

Animal Models And Experimental Medicine

Zheng, Jie J

Publication Date: 2022-02

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PubMed Link: 35229998

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• AME2-5-3.pdf

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Idebenone Regulates Aβ and LPS-Induced Neurogliosis and Cognitive Function Through Inhibition of NLRP3 Inflammasome/IL-1β Axis Activation.

Frontiers In Immunology

Lee, Hyun-Ju HJ; Park, Jin-Hee JH; Hoe, Hyang-Sook HS

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35222363

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• fimmu-13-749336.pdf

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Serum Amyloidogenic Nanoplaques and Cytokines in Alzheimer's Disease: Pilot Study in a Small Naturalistic Memory Clinic Cohort.

Journal Of Alzheimer'S Disease : Jad

Aksnes, Mari M; Aass, Hans Christian D HCD; Tiiman, Ann A; Terenius, Lars L; Bogdanović, Nenad N; Vukojević, Vladana V; Knapskog, Anne-Brita AB

Publication Date: 2022-02-21

Variant appearance in text: APP: V717I

PubMed Link: 35213378

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• jad-86-jad215504.pdf

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Neuroimaging of Mouse Models of Alzheimer's Disease.

Biomedicines

Jullienne, Amandine A; Trinh, Michelle V MV; Obenaus, Andre A

Publication Date: 2022-01-28

Variant appearance in text: APP: V717I

PubMed Link: 35203515

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• biomedicines-10-00305.pdf

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Enhancing autophagy maturation with CCZ1-MON1A complex alleviates neuropathology and memory defects in Alzheimer disease models.

Theranostics

Cai, Cui-Zan CZ; Zhuang, Xu-Xu XX; Zhu, Qi Q; Wu, Ming-Yue MY; Su, Huanxing H; Wang, Xiao-Jin XJ; Iyaswamy, Ashok A; Yue, Zhenyu Z; Wang, Qian Q; Zhang, Bin B; Xue, Yu Y; Tan, Jieqiong J; Li, Min M; He, Huanhuan H; Lu, Jia-Hong JH

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35198070

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• thnov12p1738.pdf

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Acetylcholine deficiency disrupts extratelencephalic projection neurons in the prefrontal cortex in a mouse model of Alzheimer's disease.

Nature Communications

Sun, Qingtao Q; Zhang, Jianping J; Li, Anan A; Yao, Mei M; Liu, Guangcai G; Chen, Siqi S; Luo, Yue Y; Wang, Zhi Z; Gong, Hui H; Li, Xiangning X; Luo, Qingming Q

Publication Date: 2022-02-22

Variant appearance in text: APP: V717I

PubMed Link: 35194025

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• 41467_2022_Article_28493.pdf

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Electro-Acupuncture Improve the Early Pattern Separation in Alzheimer's Disease Mice via Basal Forebrain-Hippocampus Cholinergic Neural Circuit.

Frontiers In Aging Neuroscience

Li, Long L; Li, Jianhong J; Dai, Yaling Y; Yang, Minguang M; Liang, Shengxiang S; Wang, Zhifu Z; Liu, Weilin W; Chen, Lidian L; Tao, Jing J

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 35185516

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• fnagi-13-770948.pdf

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Protective Role of Microglia on Neuronal Survival after Exposure to Amyloid Beta.

Chonnam Medical Journal

Lee, Sunjun S; Choi, Won-Seok WS

Publication Date: 2022-01

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PubMed Link: 35169554

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• Main text
• cmj-58-13.pdf

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Editorial: The Molecular Mechanisms of Synaptic Plasticity Impairments in Alzheimer's Disease.

Frontiers In Cell And Developmental Biology

Liu, Gong-Ping GP; Lei, Peng P; Dong, Zhi-Fang ZF; Li, Shu-Peng SP

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 35127687

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• Main text
• fcell-10-832728.pdf

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Sodium-calcium exchanger isoform-3 targeted Withania somnifera (L.) Dunal therapeutic intervention ameliorates cognition in the 5xFAD mouse model of Alzheimer's disease.

Scientific Reports

Afewerky, Henok Kessete HK; Li, Hao H; Zhang, Tongmei T; Li, Xinyan X; Mahaman, Yacoubou Abdoul Razak YAR; Duan, Limin L; Qin, Pengwei P; Zheng, Jiequn J; Pei, Lei L; Lu, Youming Y

Publication Date: 2022-01-27

Variant appearance in text: APP: V717I

PubMed Link: 35087161

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• Main text

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No Association between Single Nucleotide Polymorphisms (SNPs) of the Interferon-Induced Transmembrane Protein 3 (IFITM3) Gene and the Susceptibility of Alzheimer's Disease (AD).

Medicina (Kaunas, Lithuania)

Won, Sae-Young SY; Kim, Yong-Chan YC; Jeong, Byung-Hoon BH

Publication Date: 2021-12-30

Variant appearance in text: APP: V717I

PubMed Link: 35056363

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• Main text
• medicina-58-00055.pdf

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Disrupted neural correlates of anesthesia and sleep reveal early circuit dysfunctions in Alzheimer models.

Cell Reports

Zarhin, Daniel D; Atsmon, Refaela R; Ruggiero, Antonella A; Baeloha, Halit H; Shoob, Shiri S; Scharf, Oded O; Heim, Leore R LR; Buchbinder, Nadav N; Shinikamin, Ortal O; Shapira, Ilana I; Styr, Boaz B; Braun, Gabriella G; Harel, Michal M; Sheinin, Anton A; Geva, Nitzan N; Sela, Yaniv Y; Saito, Takashi T; Saido, Takaomi T; Geiger, Tamar T; Nir, Yuval Y; Ziv, Yaniv Y; Slutsky, Inna I

Publication Date: 2022-01-18

Variant appearance in text: APP: V717I

PubMed Link: 35045289

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• Main text
• mmc8.pdf

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Cognitive enhancement and neuroprotective effects of OABL, a sesquiterpene lactone in 5xFAD Alzheimer's disease mice model.

Redox Biology

Tang, Jiang-Jiang JJ; Huang, Lan-Fang LF; Deng, Jia-Le JL; Wang, Yi-Meng YM; Guo, Cong C; Peng, Xiao-Na XN; Liu, Zhigang Z; Gao, Jin-Ming JM

Publication Date: 2022-01-08

Variant appearance in text: APP: V717I

PubMed Link: 35026701

Variant Present in the following documents:

• Main text
• main.pdf

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Rapid Identification of 3,6'-Disinapoyl Sucrose Metabolites in Alzheimer's Disease Model Mice Using UHPLC-Orbitrap Mass Spectrometry.

Molecules (Basel, Switzerland)

Yuan, Jiaqi J; Wang, Han H; Wang, Yunting Y; Wang, Zijian Z; Huo, Qing Q; Dai, Xueling X; Zhang, Jiayu J; Sun, Yaxuan Y

Publication Date: 2021-12-25

Variant appearance in text: APP: V717I

PubMed Link: 35011346

Variant Present in the following documents:

• molecules-27-00114.pdf

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Microbial pathogens induce neurodegeneration in Alzheimer's disease mice: protection by microglial regulation.

Journal Of Neuroinflammation

Ganz, Tal T; Fainstein, Nina N; Elad, Amit A; Lachish, Marva M; Goldfarb, Smadar S; Einstein, Ofira O; Ben-Hur, Tamir T

Publication Date: 2022-01-06

Variant appearance in text: APP: V717I

PubMed Link: 34991645

Variant Present in the following documents:

• Main text
• 12974_2021_Article_2369.pdf

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Identification of Immune Cells and Key Genes associated with Alzheimer's Disease.

International Journal Of Medical Sciences

Liu, Chenming C; Zhang, Xi X; Chai, Huazhen H; Xu, Sutong S; Liu, Qiulu Q; Luo, Yuping Y; Li, Siguang S

Publication Date: 2022

Variant appearance in text: APP: V717I

PubMed Link: 34975305

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• ijmsv19p0112.pdf

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Identification of a Thyroid Hormone Derivative as a Pleiotropic Agent for the Treatment of Alzheimer's Disease.

Pharmaceuticals (Basel, Switzerland)

Runfola, Massimiliano M; Perni, Michele M; Yang, Xiaoting X; Marchese, Maria M; Bacci, Andrea A; Mero, Serena S; Santorelli, Filippo M FM; Polini, Beatrice B; Chiellini, Grazia G; Giuliani, Daniela D; Vilella, Antonietta A; Bodria, Martina M; Daini, Eleonora E; Vandini, Eleonora E; Rudge, Simon S; Gul, Sheraz S; Wakelam, Michale O J MOJ; Vendruscolo, Michele M; Rapposelli, Simona S

Publication Date: 2021-12-19

Variant appearance in text: APP: V717I

PubMed Link: 34959730

Variant Present in the following documents:

• pharmaceuticals-14-01330.pdf

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Conformational Models of APP Processing by Gamma Secretase Based on Analysis of Pathogenic Mutations.

International Journal Of Molecular Sciences

Kim, Meewhi M; Bezprozvanny, Ilya I

Publication Date: 2021-12-18

Variant appearance in text: APP: V717I

PubMed Link: 34948396

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• Main text
• ijms-22-13600.pdf

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The APOE ε4 Allele Affects Cognitive Functions Differently in Carriers of APP Mutations Compared to Carriers of PSEN1 Mutations in Autosomal-Dominant Alzheimer's Disease.

Genes

Almkvist, Ove O; Graff, Caroline C

Publication Date: 2021-12-07

Variant appearance in text: APP: V717I

PubMed Link: 34946903

Variant Present in the following documents:

• Main text
• genes-12-01954.pdf

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Quantitative Brain Positron Emission Tomography in Female 5XFAD Alzheimer Mice: Pathological Features and Sex-Specific Alterations.

Frontiers In Medicine

Bouter, Caroline C; Irwin, Caroline C; Franke, Timon N TN; Beindorff, Nicola N; Bouter, Yvonne Y

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 34901060

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• fmed-08-745064.pdf

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Microglia in Alzheimer's Disease: A Target for Therapeutic Intervention.

Frontiers In Cellular Neuroscience

Zhang, Guimei G; Wang, Zicheng Z; Hu, Huiling H; Zhao, Meng M; Sun, Li L

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 34899188

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• fncel-15-749587.pdf

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A Review of the Current Mammalian Models of Alzheimer's Disease and Challenges That Need to Be Overcome.

International Journal Of Molecular Sciences

Mckean, Natasha Elizabeth NE; Handley, Renee Robyn RR; Snell, Russell Grant RG

Publication Date: 2021-12-06

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PubMed Link: 34884970

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• ijms-22-13168.pdf

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Targeting MicroRNA-485-3p Blocks Alzheimer's Disease Progression.

International Journal Of Molecular Sciences

Koh, Han Seok HS; Lee, SangJoon S; Lee, Hyo Jin HJ; Min, Jae-Woong JW; Iwatsubo, Takeshi T; Teunissen, Charlotte E CE; Cho, Hyun-Jeong HJ; Ryu, Jin-Hyeob JH

Publication Date: 2021-12-04

Variant appearance in text: APP: V717I

PubMed Link: 34884940

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• Main text
• ijms-22-13136.pdf

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Magnetic Resonance Imaging in Animal Models of Alzheimer's Disease Amyloidosis.

International Journal Of Molecular Sciences

Ni, Ruiqing R

Publication Date: 2021-11-25

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PubMed Link: 34884573

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• ijms-22-12768.pdf

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Systemic inflammasome activation and pyroptosis associate with the progression of amnestic mild cognitive impairment and Alzheimer's disease.

Journal Of Neuroinflammation

Rui, Wenjuan W; Xiao, Hong H; Fan, Yi Y; Ma, Zhongxuan Z; Xiao, Ming M; Li, Sheng S; Shi, Jingping J

Publication Date: 2021-12-02

Variant appearance in text: APP: V717I

PubMed Link: 34856990

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• 12974_2021_Article_2329.pdf

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Alzheimer's Disease, Sleep Disordered Breathing, and Microglia: Puzzling out a Common Link.

Cells

Ulland, Tyler K TK; Ewald, Andrea C AC; Knutson, Andrew O AO; Marino, Kaitlyn M KM; Smith, Stephanie M C SMC; Watters, Jyoti J JJ

Publication Date: 2021-10-27

Variant appearance in text: APP: V717I

PubMed Link: 34831129

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• cells-10-02907.pdf

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Τhe Greek Variant in APP Gene: The Phenotypic Spectrum of APP Mutations.

International Journal Of Molecular Sciences

Kalampokini, Stefania S; Georgouli, Despoina D; Patrikiou, Eleni E; Provatas, Antonios A; Valotassiou, Varvara V; Georgoulias, Panagiotis P; Spanaki, Cleanthe C; Hadjigeorgiou, Georgios M GM; Xiromerisiou, Georgia G

Publication Date: 2021-11-16

Variant appearance in text: APP: V717I

PubMed Link: 34830236

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• ijms-22-12355.pdf

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Osteoblastic Swedish mutant APP expedites brain deficits by inducing endoplasmic reticulum stress-driven senescence.

Communications Biology

Pan, Jin-Xiu JX; Sun, Dong D; Lee, Daehoon D; Xiong, Lei L; Ren, Xiao X; Guo, Hao-Han HH; Yao, Ling-Ling LL; Lu, Yuyi Y; Jung, Caroline C; Xiong, Wen-Cheng WC

Publication Date: 2021-11-25

Variant appearance in text: APP: V717I

PubMed Link: 34824365

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• 42003_2021_Article_2843.pdf

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Microglia contribute to the propagation of Aβ into unaffected brain tissue.

Nature Neuroscience

d'Errico, Paolo P; Ziegler-Waldkirch, Stephanie S; Aires, Vanessa V; Hoffmann, Philippe P; Mezö, Charlotte C; Erny, Daniel D; Monasor, Laura Sebastian LS; Liebscher, Sabine S; Ravi, Vidhya M VM; Joseph, Kevin K; Schnell, Oliver O; Kierdorf, Katrin K; Staszewski, Ori O; Tahirovic, Sabina S; Prinz, Marco M; Meyer-Luehmann, Melanie M

Publication Date: 2021-11-22

Variant appearance in text: APP: V717I

PubMed Link: 34811521

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• 41593_2021_951_MOESM2_ESM.pdf
• 41593_2021_Article_951.pdf

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Identification of early-onset photoreceptor degeneration in transgenic mouse models of Alzheimer's disease.

Iscience

Zhang, Jie J; Gao, Feng F; Ma, Yuqian Y; Xue, Tian T; Shen, Yong Y

Publication Date: 2021-11-19

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PubMed Link: 34805789

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• main.pdf

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Neural Derivates of Canine Induced Pluripotent Stem Cells-Like Cells From a Mild Cognitive Impairment Dog.

Frontiers In Veterinary Science

Chandrasekaran, Abinaya A; Thomsen, Barbara Blicher BB; Agerholm, Jørgen Steen JS; Pessôa, Laís Vicari de Figueiredo LVF; Godoy Pieri, Naira Caroline NC; Sabaghidarmiyan, Vahideh V; Langley, Katarina K; Kolko, Miriam M; de Andrade, André Furugen Cesar AFC; Bressan, Fabiana Fernandes FF; Hyttel, Poul P; Berendt, Mette M; Freude, Kristine K

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 34805331

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• fvets-08-725386.pdf

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Plaque-Associated Oligomeric Amyloid-Beta Drives Early Synaptotoxicity in APP/PS1 Mice Hippocampus: Ultrastructural Pathology Analysis.

Frontiers In Neuroscience

Sanchez-Varo, Raquel R; Sanchez-Mejias, Elisabeth E; Fernandez-Valenzuela, Juan Jose JJ; De Castro, Vanessa V; Mejias-Ortega, Marina M; Gomez-Arboledas, Angela A; Jimenez, Sebastian S; Sanchez-Mico, Maria Virtudes MV; Trujillo-Estrada, Laura L; Moreno-Gonzalez, Ines I; Baglietto-Vargas, David D; Vizuete, Marisa M; Davila, Jose Carlos JC; Vitorica, Javier J; Gutierrez, Antonia A

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 34803589

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• fnins-15-752594.pdf

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Prostaglandin EP2 receptor antagonist ameliorates neuroinflammation in a two-hit mouse model of Alzheimer's disease.

Journal Of Neuroinflammation

Banik, Avijit A; Amaradhi, Radhika R; Lee, Daniel D; Sau, Michael M; Wang, Wenyi W; Dingledine, Raymond R; Ganesh, Thota T

Publication Date: 2021-11-20

Variant appearance in text: APP: V717I

PubMed Link: 34801055

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• 12974_2021_Article_2297.pdf

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Effects of Sex, Age, and Apolipoprotein E Genotype on Brain Ceramides and Sphingosine-1-Phosphate in Alzheimer's Disease and Control Mice.

Frontiers In Aging Neuroscience

den Hoedt, Sandra S; Crivelli, Simone M SM; Leijten, Frank P J FPJ; Losen, Mario M; Stevens, Jo A A JAA; Mané-Damas, Marina M; de Vries, Helga E HE; Walter, Jochen J; Mirzaian, Mina M; Sijbrands, Eric J G EJG; Aerts, Johannes M F G JMFG; Verhoeven, Adrie J M AJM; Martinez-Martinez, Pilar P; Mulder, Monique T MT

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 34776936

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• fnagi-13-765252.pdf

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A brain proteomic signature of incipient Alzheimer's disease in young APOE ε4 carriers identifies novel drug targets.

Science Advances

Roberts, Jackson A JA; Varma, Vijay R VR; An, Yang Y; Varma, Sudhir S; Candia, Julián J; Fantoni, Giovanna G; Tiwari, Vinod V; Anerillas, Carlos C; Williamson, Andrew A; Saito, Atsushi A; Loeffler, Tina T; Schilcher, Irene I; Moaddel, Ruin R; Khadeer, Mohammed M; Lovett, Jacqueline J; Tanaka, Toshiko T; Pletnikova, Olga O; Troncoso, Juan C JC; Bennett, David A DA; Albert, Marilyn S MS; Yu, Kaiwen K; Niu, Mingming M; Haroutunian, Vahram V; Zhang, Bin B; Peng, Junmin J; Croteau, Deborah L DL; Resnick, Susan M SM; Gorospe, Myriam M; Bohr, Vilhelm A VA; Ferrucci, Luigi L; Thambisetty, Madhav M

Publication Date: 2021-11-12

Variant appearance in text: APP: V717I

PubMed Link: 34757788

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• sciadv.abi8178.pdf

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Mindfulness intervention improves cognitive function in older adults by enhancing the level of miRNA-29c in neuron-derived extracellular vesicles.

Scientific Reports

Hashizume, Shin S; Nakano, Masako M; Kubota, Kenta K; Sato, Seiichi S; Himuro, Nobuaki N; Kobayashi, Eiji E; Takaoka, Akinori A; Fujimiya, Mineko M

Publication Date: 2021-11-08

Variant appearance in text: APP: V717I

PubMed Link: 34750393

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• 41598_2021_Article_1318.pdf

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Microglial transcription profiles in mouse and human are driven by APOE4 and sex.

Iscience

Moser, V Alexandra VA; Workman, Michael J MJ; Hurwitz, Samantha J SJ; Lipman, Rachel M RM; Pike, Christian J CJ; Svendsen, Clive N CN

Publication Date: 2021-11-19

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PubMed Link: 34746703

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Analysis of Genotype-Phenotype Correlations in Patients With Degenerative Dementia Through the Whole Exome Sequencing.

Frontiers In Aging Neuroscience

Sun, Lin L; Zhang, Jianye J; Su, Ning N; Zhang, Shaowei S; Yan, Feng F; Lin, Xiang X; Yu, Jie J; Li, Wei W; Li, Xia X; Xiao, Shifu S

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 34720994

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• Main text
• fnagi-13-745407.pdf

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Delivery Platforms for CRISPR/Cas9 Genome Editing of Glial Cells in the Central Nervous System.

Frontiers In Genome Editing

Meneghini, Vasco V; Peviani, Marco M; Luciani, Marco M; Zambonini, Giada G; Gritti, Angela A

Publication Date: 2021

Variant appearance in text: APP: V717I

PubMed Link: 34713256

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• fgeed-03-644319.pdf

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