Publications:

Cholesterol-lowering drugs reduce APP processing to Aβ by inducing APP dimerization.

Molecular Biology Of The Cell

Langness, Vanessa F VF; van der Kant, Rik R; Das, Utpal U; Wang, Louie L; Chaves, Rodrigo Dos Santos RDS; Goldstein, Lawrence S B LSB

Publication Date: 2021-02-01

Variant appearance in text: APP: F691A

PubMed Link: 33296223

Variant Present in the following documents:

• Main text
• mbc-32-247.pdf

View BVdb publication page

Cholesterol Metabolism Is a Druggable Axis that Independently Regulates Tau and Amyloid-β in iPSC-Derived Alzheimer's Disease Neurons.

Cell Stem Cell

van der Kant, Rik R; Langness, Vanessa F VF; Herrera, Cheryl M CM; Williams, Daniel A DA; Fong, Lauren K LK; Leestemaker, Yves Y; Steenvoorden, Evelyne E; Rynearson, Kevin D KD; Brouwers, Jos F JF; Helms, J Bernd JB; Ovaa, Huib H; Giera, Martin M; Wagner, Steven L SL; Bang, Anne G AG; Goldstein, Lawrence S B LSB

Publication Date: 2019-03-07

Variant appearance in text: APP: F691A

PubMed Link: 30686764

Variant Present in the following documents:

• Main text
• mmc1.pdf
• mmc5.pdf

View BVdb publication page