APP c.2009A>G ;(p.K670R)

Variant ID: 21-27269940-T-C

NM_000484.3(APP):c.2009A>G;(p.K670R)

This variant was identified in 4 publications

View GRCh38 version.




Publications:


Choline supplementation in early life improves and low levels of choline can impair outcomes in a mouse model of Alzheimer's disease.

Biorxiv : The Preprint Server For Biology
Chartampila, Elissavet E; Elayouby, Karim S KS; Leary, Paige P; LaFrancois, John J JJ; Alcantara-Gonzalez, David D; Jain, Swati S; Gerencer, Kasey K; Botterill, Justin J JJ; Ginsberg, Stephen D SD; Scharfman, Helen E HE
Publication Date: 2023-05-12

Variant appearance in text: APP: Lys670Arg
PubMed Link: 37214805
Variant Present in the following documents:
  • Main text
  • nihpp-2023.05.12.540428v1.pdf
View BVdb publication page



Organoids as a new model for improving regenerative medicine and cancer personalized therapy in renal diseases.

Cell Death & Disease
Grassi, Ludovica L; Alfonsi, Romina R; Francescangeli, Federica F; Signore, Michele M; De Angelis, Maria Laura ML; Addario, Antonio A; Costantini, Manuela M; Flex, Elisabetta E; Ciolfi, Andrea A; Pizzi, Simone S; Bruselles, Alessandro A; Pallocca, Matteo M; Simone, Giuseppe G; Haoui, Mustapha M; Falchi, Mario M; Milella, Michele M; Sentinelli, Steno S; Di Matteo, Paola P; Stellacci, Emilia E; Gallucci, Michele M; Muto, Giovanni G; Tartaglia, Marco M; De Maria, Ruggero R; Bonci, Désirée D
Publication Date: 2019-02-27

Variant appearance in text: APP: 2009A>G; Lys670Arg
PubMed Link: 30814510
Variant Present in the following documents:
  • 41419_2019_1453_MOESM27_ESM.xlsx, sheet 1
View BVdb publication page



Interictal spikes during sleep are an early defect in the Tg2576 mouse model of β-amyloid neuropathology.

Scientific Reports
Kam, Korey K; Duffy, Áine M ÁM; Moretto, Jillian J; LaFrancois, John J JJ; Scharfman, Helen E HE
Publication Date: 2016-01-28

Variant appearance in text: APP: Lys670Arg
PubMed Link: 26818394
Variant Present in the following documents:
  • Main text
  • srep20119.pdf
View BVdb publication page



Brain amyloid-β oligomers in ageing and Alzheimer's disease.

Brain : A Journal Of Neurology
Lesné, Sylvain E SE; Sherman, Mathew A MA; Grant, Marianne M; Kuskowski, Michael M; Schneider, Julie A JA; Bennett, David A DA; Ashe, Karen H KH
Publication Date: 2013-05

Variant appearance in text: APP: Lys670Arg
PubMed Link: 23576130
Variant Present in the following documents:
  • Main text
View BVdb publication page