APP c.2008_2009delinsCT ;(p.K670L)

Variant ID: 21-27269940-TT-AG

NM_000484.3(APP):c.2008_2009delinsCT;(p.K670L)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Tau immunotherapy modulates both pathological tau and upstream amyloid pathology in an Alzheimer's disease mouse model.

The Journal Of Neuroscience : The Official Journal Of The Society For Neuroscience
Castillo-Carranza, Diana L DL; Guerrero-Muñoz, Marcos J MJ; Sengupta, Urmi U; Hernandez, Caterina C; Barrett, Alan D T AD; Dineley, Kelly K; Kayed, Rakez R
Publication Date: 2015-03-25

Variant appearance in text: APP: K670L
PubMed Link: 25810517
Variant Present in the following documents:
  • Main text
View BVdb publication page



Advances in the pathogenesis of Alzheimer's disease: a re-evaluation of amyloid cascade hypothesis.

Translational Neurodegeneration
Dong, Suzhen S; Duan, Yale Y; Hu, Yinghe Y; Zhao, Zheng Z
Publication Date: 2012-09-21

Variant appearance in text: APP: K670L
PubMed Link: 23210692
Variant Present in the following documents:
  • Main text
  • 2047-9158-1-18.pdf
View BVdb publication page



Anti-PrPC monoclonal antibody infusion as a novel treatment for cognitive deficits in an Alzheimer's disease model mouse.

Bmc Neuroscience
Chung, Erika E; Ji, Yong Y; Sun, Yanjie Y; Kascsak, Richard J RJ; Kascsak, Regina B RB; Mehta, Pankaj D PD; Strittmatter, Stephen M SM; Wisniewski, Thomas T
Publication Date: 2010-10-14

Variant appearance in text: APP: K670L
PubMed Link: 20946660
Variant Present in the following documents:
  • Main text
  • 1471-2202-11-130.pdf
View BVdb publication page



Days to criterion as an indicator of toxicity associated with human Alzheimer amyloid-beta oligomers.

Annals Of Neurology
Gandy, Sam S; Simon, Adam J AJ; Steele, John W JW; Lublin, Alex L AL; Lah, James J JJ; Walker, Lary C LC; Levey, Allan I AI; Krafft, Grant A GA; Levy, Efrat E; Checler, Frédéric F; Glabe, Charles C; Bilker, Warren B WB; Abel, Ted T; Schmeidler, James J; Ehrlich, Michelle E ME
Publication Date: 2010-08

Variant appearance in text: APP: K670L
PubMed Link: 20641005
Variant Present in the following documents:
  • Main text
View BVdb publication page



Blocking the apolipoprotein E/amyloid-beta interaction as a potential therapeutic approach for Alzheimer's disease.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Sadowski, Martin J MJ; Pankiewicz, Joanna J; Scholtzova, Henrieta H; Mehta, Pankaj D PD; Prelli, Frances F; Quartermain, David D; Wisniewski, Thomas T
Publication Date: 2006-12-05

Variant appearance in text: APP: K670L
PubMed Link: 17116874
Variant Present in the following documents:
  • Main text
View BVdb publication page