Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Giovinazzo, Daniel D; Bursac, Biljana B; Sbodio, Juan I JI; Nalluru, Sumedha S; Vignane, Thibaut T; Snowman, Adele M AM; Albacarys, Lauren M LM; Sedlak, Thomas W TW; Torregrossa, Roberta R; Whiteman, Matthew M; Filipovic, Milos R MR; Snyder, Solomon H SH; Paul, Bindu D BD
Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions.
Scientific Reports
Liu, Mengyu M; Dexheimer, Thomas T; Sui, Dexin D; Hovde, Stacy S; Deng, Xiexiong X; Kwok, Roland R; Bochar, Daniel A DA; Kuo, Min-Hao MH