APP c.872G>C ;(p.C291S)

Variant ID: 21-27372491-C-G

NM_000484.3(APP):c.872G>C;(p.C291S)

This variant was identified in 3 publications

View GRCh38 version.




Publications:


Hydrogen sulfide is neuroprotective in Alzheimer's disease by sulfhydrating GSK3β and inhibiting Tau hyperphosphorylation.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Giovinazzo, Daniel D; Bursac, Biljana B; Sbodio, Juan I JI; Nalluru, Sumedha S; Vignane, Thibaut T; Snowman, Adele M AM; Albacarys, Lauren M LM; Sedlak, Thomas W TW; Torregrossa, Roberta R; Whiteman, Matthew M; Filipovic, Milos R MR; Snyder, Solomon H SH; Paul, Bindu D BD
Publication Date: 2021-01-26

Variant appearance in text: APP: C291S
PubMed Link: 33431651
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hyperphosphorylated tau aggregation and cytotoxicity modulators screen identified prescription drugs linked to Alzheimer's disease and cognitive functions.

Scientific Reports
Liu, Mengyu M; Dexheimer, Thomas T; Sui, Dexin D; Hovde, Stacy S; Deng, Xiexiong X; Kwok, Roland R; Bochar, Daniel A DA; Kuo, Min-Hao MH
Publication Date: 2020-10-06

Variant appearance in text: APP: C291S
PubMed Link: 33024171
Variant Present in the following documents:
  • Main text
  • 41598_2020_Article_73680.pdf
View BVdb publication page



Natural product-based amyloid inhibitors.

Biochemical Pharmacology
Velander, Paul P; Wu, Ling L; Henderson, Frances F; Zhang, Shijun S; Bevan, David R DR; Xu, Bin B
Publication Date: 2017-09-01

Variant appearance in text: APP: C291S
PubMed Link: 28390938
Variant Present in the following documents:
  • Main text
View BVdb publication page