Pharmacogenomic profile of actionable molecular variants related to drugs commonly used in anesthesia: WES analysis reveals new mutations.
Frontiers In Pharmacology
Parada-Márquez, Juan Fernando JF; Maldonado-Rodriguez, Nicolás David ND; Triana-Fonseca, Paula P; Contreras-Bravo, Nora Constanza NC; Calderón-Ospina, Carlos Alberto CA; Restrepo, Carlos M CM; Morel, Adrien A; Ortega-Recalde, Oscar Javier OJ; Silgado-Guzmán, Daniel Felipe DF; Angulo-Aguado, Mariana M; Fonseca-Mendoza, Dora Janeth DJ
Genome-wide association studies of metabolites in Finnish men identify disease-relevant loci.
Nature Communications
Yin, Xianyong X; Chan, Lap Sum LS; Bose, Debraj D; Jackson, Anne U AU; VandeHaar, Peter P; Locke, Adam E AE; Fuchsberger, Christian C; Stringham, Heather M HM; Welch, Ryan R; Yu, Ketian K; Fernandes Silva, Lilian L; Service, Susan K SK; Zhang, Daiwei D; Hector, Emily C EC; Young, Erica E; Ganel, Liron L; Das, Indraniel I; Abel, Haley H; Erdos, Michael R MR; Bonnycastle, Lori L LL; Kuusisto, Johanna J; Stitziel, Nathan O NO; Hall, Ira M IM; Wagner, Gregory R GR; , ; Kang, Jian J; Morrison, Jean J; Burant, Charles F CF; Collins, Francis S FS; Ripatti, Samuli S; Palotie, Aarno A; Freimer, Nelson B NB; Mohlke, Karen L KL; Scott, Laura J LJ; Wen, Xiaoquan X; Fauman, Eric B EB; Laakso, Markku M; Boehnke, Michael M
COMT Val/Met and Psychopathic Traits in Children and Adolescents: A Systematic Review and New Evidence of a Developmental Trajectory toward Psychopathy.
International Journal Of Molecular Sciences
Kant, Tuana T; Koyama, Emiko E; Zai, Clement C CC; Beitchman, Joseph H JH; Kennedy, James L JL
Publication Date: 2022-02-04
Variant appearance in text: COMT: Ala72Ser; rs6267
COMT Val/Met and Psychopathic Traits in Children and Adolescents: A Systematic Review and New Evidence of a Developmental Trajectory toward Psychopathy.
International Journal Of Molecular Sciences
Kant, Tuana T; Koyama, Emiko E; Zai, Clement C CC; Beitchman, Joseph H JH; Kennedy, James L JL
Publication Date: 2022-02-04
Variant appearance in text: COMT: Ala72Ser; rs6267
Interaction between dietary total antioxidant capacity and BDNF Val66Met polymorphism on lipid profiles and atherogenic indices among diabetic patients.
Scientific Reports
Abaj, Faezeh F; Rafiee, Masoumeh M; Koohdani, Fariba F
Association of FAAH p.Pro129Thr and COMT p.Ala72Ser with schizophrenia and comorbid substance use through next-generation sequencing: an exploratory analysis.
Revista Brasileira De Psiquiatria (Sao Paulo, Brazil : 1999)
Martínez-Magaña, José J JJ; Genis-Mendoza, Alma D AD; González-Covarrubias, Vanessa V; Juárez-Rojop, Isela E IE; Tovilla-Zárate, Carlos A CA; Soberón, Xavier X; Lanzagorta, Nuria N; Nicolini, Humberto H
Publication Date: 2022
Variant appearance in text: COMT: Ala72Ser; rs6267
Actionable pharmacogenetic variants in Hong Kong Chinese exome sequencing data and projected prescription impact in the Hong Kong population.
Plos Genetics
Yu, Mullin Ho Chung MHC; Chan, Marcus Chun Yin MCY; Chung, Claudia Ching Yan CCY; Li, Andrew Wang Tat AWT; Yip, Chara Yin Wa CYW; Mak, Christopher Chun Yu CCY; Chau, Jeffrey Fong Ting JFT; Lee, Mianne M; Fung, Jasmine Lee Fong JLF; Tsang, Mandy Ho Yin MHY; Chan, Joshua Chun Ki JCK; Wong, Wilfred Hing Sang WHS; Yang, Jing J; Chui, William Chun Ming WCM; Chung, Patrick Ho Yu PHY; Yang, Wanling W; Lee, So Lun SL; Chan, Godfrey Chi Fung GCF; Tam, Paul Kwong Hang PKH; Lau, Yu Lung YL; Tang, Clara Sze Man CSM; Yeung, Kit San KS; Chung, Brian Hon Yin BHY
A candidate gene study of risk for dementia in older, postmenopausal women: Results from the Women's Health Initiative Memory Study.
International Journal Of Geriatric Psychiatry
Driscoll, Ira I; Snively, Beverly M BM; Espeland, Mark A MA; Shumaker, Sally A SA; Rapp, Stephen R SR; Goveas, Joseph S JS; Casanova, Ramon L RL; Wactawski-Wende, Jean J; Manson, JoAnn E JE; Rossom, Rebecca R; Brooks, Janet J; Hernandez, Dena G DG; Singleton, Andrew B AB; Resnick, Susan M SM
Complete Disruption of Autism-Susceptibility Genes by Gene Editing Predominantly Reduces Functional Connectivity of Isogenic Human Neurons.
Stem Cell Reports
Deneault, Eric E; White, Sean H SH; Rodrigues, Deivid C DC; Ross, P Joel PJ; Faheem, Muhammad M; Zaslavsky, Kirill K; Wang, Zhuozhi Z; Alexandrova, Roumiana R; Pellecchia, Giovanna G; Wei, Wei W; Piekna, Alina A; Kaur, Gaganjot G; Howe, Jennifer L JL; Kwan, Vickie V; Thiruvahindrapuram, Bhooma B; Walker, Susan S; Lionel, Anath C AC; Pasceri, Peter P; Merico, Daniele D; Yuen, Ryan K C RKC; Singh, Karun K KK; Ellis, James J; Scherer, Stephen W SW
Interaction Between Environmental Risk Factors and Catechol-O-Methyltransferase (COMT) and X-Ray Repair Cross-Complementing Protein 1 (XRCC1) Gene Polymorphisms in Risk of Lung Cancer Among Non-Smoking Chinese Women: A Case-Control Study.
Medical Science Monitor : International Medical Journal Of Experimental And Clinical Research
Pan, Jian-Liang JL; Gao, Jin J; Hou, Jian-Hua JH; Hu, De-Zhong DZ; Li, Lin L
Interacting Effect of Catechol-O-Methyltransferase (COMT) and Monoamine Oxidase A (MAOA) Gene Polymorphisms, and Stressful Life Events on Aggressive Behavior in Chinese Male Adolescents.
Frontiers In Psychology
Wang, Meiping M; Li, Hailei H; Deater-Deckard, Kirby K; Zhang, Wenxin W
Publication Date: 2018
Variant appearance in text: COMT: Ala72Ser; rs6267
Discovery of coding regions in the human genome by integrated proteogenomics analysis workflow.
Nature Communications
Zhu, Yafeng Y; Orre, Lukas M LM; Johansson, Henrik J HJ; Huss, Mikael M; Boekel, Jorrit J; Vesterlund, Mattias M; Fernandez-Woodbridge, Alejandro A; Branca, Rui M M RMM; Lehtiö, Janne J