Variant ID: 22-44324727-C-G

NM_025225.2(PNPLA3):c.444C>G;(p.I148M)

This variant was identified in 1240 publications

View GRCh38 version.




Publications:


Advances in pediatric non-alcoholic fatty liver disease: From genetics to lipidomics.

World Journal Of Clinical Pediatrics
Riccio, Simona S; Melone, Rosa R; Vitulano, Caterina C; Guida, Pierfrancesco P; Maddaluno, Ivan I; Guarino, Stefano S; Marzuillo, Pierluigi P; Miraglia Del Giudice, Emanuele E; Di Sessa, Anna A
Publication Date: 2022-05-09

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35663007
Variant Present in the following documents:
  • WJCP-11-221.pdf
View BVdb publication page



Two differentially methylated region networks in nonalcoholic fatty liver disease, viral hepatitis, and hepatocellular carcinoma.

Bmc Gastroenterology
Kurokawa, Suguru S; Yoneda, Masato M; Ogawa, Yuji Y; Honda, Yasushi Y; Kessoku, Takaomi T; Imajo, Kento K; Saito, Satoru S; Nakajima, Atsushi A; Hotta, Kikuko K
Publication Date: 2022-06-02

Variant appearance in text: rs738409
PubMed Link: 35655171
Variant Present in the following documents:
  • 12876_2022_Article_2360.pdf
View BVdb publication page



Interaction effect between NAFLD severity and high carbohydrate diet on gut microbiome alteration and hepatic de novo lipogenesis.

Gut Microbes
Kang, Hyena H; You, Hyun Ju HJ; Lee, Giljae G; Lee, Seung Hyun SH; Yoo, Taekyung T; Choi, Murim M; Joo, Sae Kyung SK; Park, Jeong Hwan JH; Chang, Mee Soo MS; Lee, Dong Hyeon DH; Kim, Won W; Ko, GwangPyo G; ,
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35634707
Variant Present in the following documents:
  • Main text
  • KGMI_14_2078612.pdf
View BVdb publication page



Non-Alcoholic Fatty Liver Disease in Long-Term Type 2 Diabetes: Role of rs738409 PNPLA3 and rs499765 FGF21 Polymorphisms and Serum Biomarkers.

Molecules (Basel, Switzerland)
Mana, Mauy Frujuello MF; Parisi, Maria Cândida R MCR; Correa-Giannella, Maria Lucia ML; Neto, Arnaldo Moura AM; Yamanaka, Ademar A; Cunha-Silva, Marlone M; Cavaleiro, Ana Mercedes AM; Dos Santos, Cristina Rodrigues CR; Pavan, Célia Regina CR; Sevá-Pereira, Tiago T; Dertkigil, Sergio S J SSJ; Mazo, Daniel F DF
Publication Date: 2022-05-17

Variant appearance in text: rs738409
PubMed Link: 35630668
Variant Present in the following documents:
  • Main text
  • molecules-27-03193.pdf
View BVdb publication page



Trust Your Gut: The Association of Gut Microbiota and Liver Disease.

Microorganisms
Manzoor, Ridda R; Ahmed, Weshah W; Afify, Nariman N; Memon, Mashal M; Yasin, Maryam M; Memon, Hamda H; Rustom, Mohammad M; Al Akeel, Mohannad M; Alhajri, Noora N
Publication Date: 2022-05-18

Variant appearance in text: rs738409
PubMed Link: 35630487
Variant Present in the following documents:
  • microorganisms-10-01045.pdf
View BVdb publication page



Association of Low Skeletal Muscle Mass with the Phenotype of Lean Non-Alcoholic Fatty Liver Disease.

Healthcare (Basel, Switzerland)
Byeon, Jun-Hyeon JH; Kang, Min-Kyu MK; Kim, Min-Cheol MC
Publication Date: 2022-05-05

Variant appearance in text: rs738409
PubMed Link: 35627987
Variant Present in the following documents:
  • Main text
  • healthcare-10-00850.pdf
View BVdb publication page



Dietary Intake and Genetic Background Influence Vitamin Needs during Pregnancy.

Healthcare (Basel, Switzerland)
Bertuccio, Maria Paola MP; Currò, Monica M; Caccamo, Daniela D; Ientile, Riccardo R
Publication Date: 2022-04-21

Variant appearance in text: rs738409
PubMed Link: 35627905
Variant Present in the following documents:
  • Main text
  • healthcare-10-00768.pdf
View BVdb publication page



Influence of Type 2 Diabetes in the Association of PNPLA3 rs738409 and TM6SF2 rs58542926 Polymorphisms in NASH Advanced Liver Fibrosis.

Biomedicines
Gabriel-Medina, Pablo P; Ferrer-Costa, Roser R; Rodriguez-Frias, Francisco F; Ciudin, Andreea A; Augustin, Salvador S; Rivera-Esteban, Jesus J; Pericàs, Juan M JM; Selva, David Martinez DM
Publication Date: 2022-04-28

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35625751
Variant Present in the following documents:
  • Main text
  • biomedicines-10-01015.pdf
View BVdb publication page



FOXA3 Polymorphisms Are Associated with Metabolic Parameters in Individuals with Subclinical Atherosclerosis and Healthy Controls-The GEA Mexican Study.

Biomolecules
Vargas-Alarcón, Gilberto G; Fragoso, José Manuel JM; Ramírez-Bello, Julian J; Posadas-Sánchez, Rosalinda R
Publication Date: 2022-04-19

Variant appearance in text: rs738409
PubMed Link: 35625529
Variant Present in the following documents:
  • biomolecules-12-00601.pdf
View BVdb publication page



SIRT1 mediates nutritional regulation of SREBP-1c-driven hepatic PNPLA3 transcription via modulation of H3k9 acetylation.

Genes And Environment : The Official Journal Of The Japanese Environmental Mutagen Society
Xu, Xiao X; Deng, Xiaojie X; Chen, Yunzhi Y; Xu, Wen W; Xu, Fen F; Liang, Hua H
Publication Date: 2022-05-27

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35624499
Variant Present in the following documents:
  • Main text
  • 41021_2022_Article_246.pdf
View BVdb publication page



The current role of sodium-glucose cotransporter 2 inhibitors in type 2 diabetes mellitus management.

Cardiovascular Diabetology
Xu, Bo B; Li, Shaoqian S; Kang, Bo B; Zhou, Jiecan J
Publication Date: 2022-05-25

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35614469
Variant Present in the following documents:
  • Main text
  • 12933_2022_Article_1512.pdf
View BVdb publication page



Association between rs738409 and rs2896019 single-nucleotide polymorphisms of phospholipase domain-containing protein 3 and susceptibility to nonalcoholic fatty liver disease in Greek children and adolescents.

Annals Of Gastroenterology
Stasinou, Eleanna E; Argyraki, Maria M; Sotiriadou, Fotini F; Lambropoulos, Alexandros A; Fotoulaki, Maria M
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35599930
Variant Present in the following documents:
  • Main text
  • AnnGastroenterol-35-297.pdf
View BVdb publication page



Emerging advances in the pharmacologic treatment of nonalcoholic steatohepatitis and related cirrhosis.

Annals Of Gastroenterology
Sinakos, Emmanouil E; Liava, Christina C; Loomba, Rohit R
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35599922
Variant Present in the following documents:
  • AnnGastroenterol-35-213.pdf
View BVdb publication page



Expression of Membrane Bound O-Acyltransferase Domain Containing 7 after Myocardial Infarction and its Role in Lipid Metabolism in vitro.

International Journal Of Medical Sciences
Li, Xiangdong X; Wang, Zhiyuan Z; Meng, Heyu H; Meng, Fanbo F; Yang, Ping P
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35582424
Variant Present in the following documents:
  • ijmsv19p0609.pdf
View BVdb publication page



Epidemiology and lifestyle survey of non-alcoholic fatty liver disease in school-age children and adolescents in Shenyang, Liaoning.

Bmc Pediatrics
Lin, Guan G; Xinhe, Zhang Z; Haoyu, Tian T; Xing, Jin J; Dan, Li L; Ningning, Wang W; Jing, Sun S; Xue, Wang W; Zilu, Zeng Z; Yiling, Li L
Publication Date: 2022-05-17

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35581572
Variant Present in the following documents:
  • 12887_2022_Article_3351.pdf
View BVdb publication page



63rd Annual Meeting of the Austrian Society of Surgery.

European Surgery : Aca : Acta Chirurgica Austriaca
Publication Date: 2022-05-11

Variant appearance in text: rs738409
PubMed Link: 35578629
Variant Present in the following documents:
  • 10353_2022_Article_763.pdf
View BVdb publication page



Genetic Variations of Vitamin A-Absorption and Storage-Related Genes, and Their Potential Contribution to Vitamin A Deficiency Risks Among Different Ethnic Groups.

Frontiers In Nutrition
Suzuki, Masako M; Tomita, Meika M
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35571879
Variant Present in the following documents:
  • fnut-09-861619.pdf
View BVdb publication page



"Big Data" Approaches for Prevention of the Metabolic Syndrome.

Frontiers In Genetics
Jiang, Xinping X; Yang, Zhang Z; Wang, Shuai S; Deng, Shuanglin S
Publication Date: 2022

Variant appearance in text: PNPLA3: Ile148Met
PubMed Link: 35571045
Variant Present in the following documents:
  • fgene-13-810152.pdf
View BVdb publication page



Liver Steatosis: A Marker of Metabolic Risk in Children.

International Journal Of Molecular Sciences
Neri, Costanza Renata CR; Scapaticci, Serena S; Chiarelli, Francesco F; Giannini, Cosimo C
Publication Date: 2022-04-27

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35563210
Variant Present in the following documents:
  • ijms-23-04822.pdf
View BVdb publication page



Coagulation and Endothelial Dysfunction Associated with NAFLD: Current Status and Therapeutic Implications.

Journal Of Clinical And Translational Hepatology
Ogresta, Doris D; Mrzljak, Anna A; Cigrovski Berkovic, Maja M; Bilic-Curcic, Ines I; Stojsavljevic-Shapeski, Sanja S; Virovic-Jukic, Lucija L
Publication Date: 2022-04-28

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35528987
Variant Present in the following documents:
  • JCTH-10-339.pdf
View BVdb publication page



Interaction of SAMM50-rs738491, PARVB-rs5764455 and PNPLA3-rs738409 Increases Susceptibility to Nonalcoholic Steatohepatitis.

Journal Of Clinical And Translational Hepatology
Xu, Ke K; Zheng, Kenneth I KI; Zhu, Pei-Wu PW; Liu, Wen-Yue WY; Ma, Hong-Lei HL; Li, Gang G; Tang, Liang-Jie LJ; Rios, Rafael S RS; Targher, Giovanni G; Byrne, Christopher D CD; Wang, Xiao-Dong XD; Chen, Yong-Ping YP; Zheng, Ming-Hua MH
Publication Date: 2022-04-28

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35528982
Variant Present in the following documents:
  • JCTH-10-219.pdf
View BVdb publication page



Recent Progress and Future Direction for the Application of Multiomics Data in Clinical Liver Transplantation.

Journal Of Clinical And Translational Hepatology
Liu, Zhengtao Z; Xu, Jun J; Que, Shuping S; Geng, Lei L; Zhou, Lin L; Mardinoglu, Adil A; Zheng, Shusen S
Publication Date: 2022-04-28

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35528975
Variant Present in the following documents:
  • JCTH-10-363.pdf
View BVdb publication page



CROATIAN GUIDELINES FOR THE DIAGNOSIS AND TREATMENT OF NONALCOHOLIC FATTY LIVER DISEASE.

Acta Clinica Croatica
Virović Jukić, Lucija L; Grgurević, Ivica I; Mikolašević, Ivana I; Filipec Kanižaj, Tajana T; Milić, Sandra S; Mrzljak, Anna A; Premužić, Marina M; Hrstić, Irena I; Knežević-Štromar, Ivana I; Ljubičić, Neven N; Ostojić, Rajko R; Stojsavljević Shapeski, Sanja S; Amerl-Šakić, Vjekoslava V; Marković, Nina Bašić NB; Rađa, Marko M; Soldo, Dragan D; Sobočan, Nikola N; Lalovac, Miloš M; Puljiz, Željko Ž; Podrug, Kristian K; Ladić, Dinko D
Publication Date: 2021-12

Variant appearance in text: rs738409
PubMed Link: 35528151
Variant Present in the following documents:
  • acc-60-supl2-36.pdf
View BVdb publication page



An optimal variant to gene distance window derived from an empirical definition of cis and trans protein QTLs.

Bmc Bioinformatics
Fauman, Eric B EB; Hyde, Craig C
Publication Date: 2022-05-08

Variant appearance in text: rs738409
PubMed Link: 35527238
Variant Present in the following documents:
View BVdb publication page



Sociodemographic and genetic determinants of nonalcoholic fatty liver disease in type 2 diabetes mellitus patients.

Journal, Genetic Engineering & Biotechnology
Adnan, Muhammad M; Wajid, Abdul A; Noor, Wasif W; Batool, Andleeb A; Aasim, Muhammad M; Abbas, Kamran K; Ain, Quratul Q
Publication Date: 2022-04-29

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35486295
Variant Present in the following documents:
  • 43141_2022_Article_349.pdf
View BVdb publication page



Potential Therapeutic Targets and Promising Agents for Combating NAFLD.

Biomedicines
Umemura, Atsushi A; Kataoka, Seita S; Okuda, Keiichiro K; Seko, Yuya Y; Yamaguchi, Kanji K; Moriguchi, Michihisa M; Okanoue, Takeshi T; Itoh, Yoshito Y
Publication Date: 2022-04-14

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35453652
Variant Present in the following documents:
  • biomedicines-10-00901.pdf
View BVdb publication page



Potential Blood DNA Methylation Biomarker Genes for Diagnosis of Liver Fibrosis in Patients With Biopsy-Proven Non-alcoholic Fatty Liver Disease.

Frontiers In Medicine
Sun, Qing-Feng QF; Tang, Liang-Jie LJ; Wang, Ming-Jie MJ; Zhu, Pei-Wu PW; Li, Yang-Yang YY; Ma, Hong-Lei HL; Huang, Ou-Yang OY; Hong, Liang L; Li, Gang G; Byrne, Christopher D CD; Targher, Giovanni G; Liu, Wen-Yue WY; Lu, Yan Y; Ding, Ji-Guang JG; Zheng, Ming-Hua MH
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35433752
Variant Present in the following documents:
  • fmed-09-864570.pdf
View BVdb publication page



Impact of PNPLA3 p.I148M and Hepatic Steatosis on Long-Term Outcomes for Hepatocellular Carcinoma and HBsAg Seroclearance in Chronic Hepatitis B.

Journal Of Hepatocellular Carcinoma
Hsueh, Rei-Chi RC; Wu, Wan-Jung WJ; Lin, Chih-Lin CL; Liu, Chun-Jen CJ; Huang, Yi-Wen YW; Hu, Jui-Ting JT; Wu, Chih-Feng CF; Sung, Feng-Yu FY; Liu, Wen-Jie WJ; Yu, Ming-Whei MW
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35433529
Variant Present in the following documents:
  • jhc-9-301.pdf
View BVdb publication page



Magnetic Resonance Imaging Assessment of Abdominal Ectopic Fat Deposition in Correlation With Cardiometabolic Risk Factors.

Frontiers In Endocrinology
Zhang, Qin-He QH; Xie, Lu-Han LH; Zhang, Hao-Nan HN; Liu, Jing-Hong JH; Zhao, Ying Y; Chen, Li-Hua LH; Ju, Ye Y; Chen, An-Liang AL; Wang, Nan N; Song, Qing-Wei QW; Xie, Li-Zhi LZ; Liu, Ai-Lian AL
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35432188
Variant Present in the following documents:
  • fendo-13-820023.pdf
View BVdb publication page



Empowering consumers to PREVENT diet-related diseases through OMICS sciences (PREVENTOMICS): protocol for a parallel double-blinded randomised intervention trial to investigate biomarker-based nutrition plans for weight loss.

Bmj Open
Aldubayan, Mona Adnan MA; Pigsborg, Kristina K; Gormsen, Sophia M O SMO; Serra, Francisca F; Palou, Mariona M; Mena, Pedro P; Wetzels, Mart M; Calleja, Alberto A; Caimari, Antoni A; Del Bas, Josep J; Gutierrez, Biotza B; Magkos, Faidon F; Hjorth, Mads Fiil MF
Publication Date: 2022-03-29

Variant appearance in text: rs738409
PubMed Link: 35351696
Variant Present in the following documents:
  • bmjopen-2021-051285.draft_revisions.pdf
  • bmjopen-2021-051285.pdf
View BVdb publication page



Advances in pig models of human diseases.

Animal Models And Experimental Medicine
Hou, Naipeng N; Du, Xuguang X; Wu, Sen S
Publication Date: 2022-03-27

Variant appearance in text: rs738409
PubMed Link: 35343091
Variant Present in the following documents:
  • AME2-5-141.pdf
View BVdb publication page



Metabolic dysfunction-related liver disease as a risk factor for cancer.

Bmj Open Gastroenterology
Taylor, Alasdair A; Siddiqui, Moneeza K MK; Ambery, Philip P; Armisen, Javier J; Challis, Benjamin G BG; Haefliger, Carolina C; Pearson, Ewan R ER; Doney, Alex S F ASF; Dillon, John F JF; Palmer, Colin N A CNA
Publication Date: 2022-03

Variant appearance in text: rs738409
PubMed Link: 35338048
Variant Present in the following documents:
  • bmjgast-2021-000817.pdf
View BVdb publication page



The association between rs1260326 with the risk of NAFLD and the mediation effect of triglyceride on NAFLD in the elderly Chinese Han population.

Aging
Yuan, Fan F; Gu, Zhan Z; Bi, Yan Y; Yuan, Ruixue R; Niu, Weibo W; Ren, Decheng D; Zhang, Lei L; He, Guang G; Liu, Bao-Cheng BC
Publication Date: 2022-03-25

Variant appearance in text: rs738409
PubMed Link: 35333773
Variant Present in the following documents:
  • aging-14-203970.pdf
View BVdb publication page



Recent Epidemiology and Risk Factors of Nonalcoholic Fatty Liver Disease.

Journal Of Obesity & Metabolic Syndrome
Huh, Youn Y; Cho, Yoon Jeong YJ; Nam, Ga Eun GE
Publication Date: 2022-03-25

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35332111
Variant Present in the following documents:
  • jomes-31-1-17.pdf
View BVdb publication page



NAFLD in normal weight individuals.

Diabetology & Metabolic Syndrome
DiStefano, Johanna K JK; Gerhard, Glenn S GS
Publication Date: 2022-03-24

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35331317
Variant Present in the following documents:
  • 13098_2022_Article_814.pdf
View BVdb publication page



Type 2 Diabetes, PNPLA3 rs738409 Polymorphism, and the Risk of Liver Cirrhosis: Analysis of Taiwan Biobank.

Frontiers In Genetics
Hsueh, Kuan-Chun KC; Nfor, Oswald Ndi ON; Hsu, Shu-Yi SY; Yang, Shun-Fa SF; Liaw, Yung-Po YP
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35330730
Variant Present in the following documents:
  • fgene-13-822700.pdf
View BVdb publication page



Whole Exome Sequencing in Healthy Individuals of Extreme Constitution Types Reveals Differential Disease Risk: A Novel Approach towards Predictive Medicine.

Journal Of Personalized Medicine
Abbas, Tahseen T; Chaturvedi, Gaura G; Prakrithi, P P; Pathak, Ankit Kumar AK; Kutum, Rintu R; Dakle, Pushkar P; Narang, Ankita A; Manchanda, Vijeta V; Patil, Rutuja R; Aggarwal, Dhiraj D; Girase, Bhushan B; Srivastava, Ankita A; Kapoor, Manav M; Gupta, Ishaan I; Pandey, Rajesh R; Juvekar, Sanjay S; Dash, Debasis D; Mukerji, Mitali M; Prasher, Bhavana B
Publication Date: 2022-03-18

Variant appearance in text: rs738409
PubMed Link: 35330488
Variant Present in the following documents:
  • jpm-12-00489.pdf
View BVdb publication page



Phenotypic Variability in Phelan-McDermid Syndrome and Its Putative Link to Environmental Factors.

Genes
Boccuto, Luigi L; Mitz, Andrew A; Abenavoli, Ludovico L; Sarasua, Sara M SM; Bennett, William W; Rogers, Curtis C; DuPont, Barbara B; Phelan, Katy K
Publication Date: 2022-03-17

Variant appearance in text: PNPLA3: Ile148Met
PubMed Link: 35328081
Variant Present in the following documents:
  • genes-13-00528.pdf
View BVdb publication page



Clinical and Genetic Aspects of Phelan-McDermid Syndrome: An Interdisciplinary Approach to Management.

Genes
Cammarata-Scalisi, Francisco F; Callea, Michele M; Martinelli, Diego D; Willoughby, Colin Eric CE; Tadich, Antonio Cárdenas AC; Araya Castillo, Maykol M; Lacruz-Rengel, María Angelina MA; Medina, Marco M; Grimaldi, Piercesare P; Bertini, Enrico E; Nevado, Julián J
Publication Date: 2022-03-12

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35328058
Variant Present in the following documents:
  • genes-13-00504.pdf
View BVdb publication page



Metabolic Syndrome but Not Fatty Liver-Associated Genetic Variants Correlates with Glomerular Renal Function Decline in Patients with Non-Alcoholic Fatty Liver Disease.

Biomedicines
Baratta, Francesco F; D'Erasmo, Laura L; Di Costanzo, Alessia A; Umbro, Ilaria I; Pastori, Daniele D; Angelico, Francesco F; Del Ben, Maria M
Publication Date: 2022-03-19

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35327522
Variant Present in the following documents:
  • biomedicines-10-00720.pdf
View BVdb publication page



The Yin-Yang Concept of Pediatric Obesity and Gut Microbiota.

Biomedicines
Meliț, Lorena Elena LE; Mărginean, Cristina Oana CO; Săsăran, Maria Oana MO
Publication Date: 2022-03-10

Variant appearance in text: rs738409
PubMed Link: 35327446
Variant Present in the following documents:
  • biomedicines-10-00645.pdf
View BVdb publication page



Rodent models and metabolomics in non-alcoholic fatty liver disease: What can we learn?

World Journal Of Hepatology
Martin-Grau, Maria M; Marrachelli, Vannina G VG; Monleon, Daniel D
Publication Date: 2022-02-27

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35317178
Variant Present in the following documents:
  • WJH-14-304.pdf
View BVdb publication page



Hepatocellular carcinoma in patients with metabolic dysfunction-associated fatty liver disease: Can we stratify at-risk populations?

World Journal Of Hepatology
Fassio, Eduardo E; Barreyro, Fernando J FJ; Pérez, M Soledad MS; Dávila, Diana D; Landeira, Graciela G; Gualano, Gisela G; Ruffillo, Gabriela G
Publication Date: 2022-02-27

Variant appearance in text: PNPLA3: 444C>G; rs738409
PubMed Link: 35317172
Variant Present in the following documents:
  • WJH-14-354.pdf
View BVdb publication page



Clinical implications of diabetes in chronic liver disease: Diagnosis, outcomes and management, current and future perspectives.

World Journal Of Gastroenterology
García-Compeán, Diego D; Orsi, Emanuela E; Kumar, Ramesh R; Gundling, Felix F; Nishida, Tsutomu T; Villarreal-Pérez, Jesús Zacarías JZ; Del Cueto-Aguilera, Ángel N ÁN; González-González, José A JA; Pugliese, Giuseppe G
Publication Date: 2022-02-28

Variant appearance in text: rs738409
PubMed Link: 35317103
Variant Present in the following documents:
  • WJG-28-775.pdf
View BVdb publication page



Beneficial Metabolic Effects of Praliciguat, a Soluble Guanylate Cyclase Stimulator, in a Mouse Diet-Induced Obesity Model.

Frontiers In Pharmacology
Schwartzkopf, Chad D CD; Hadcock, John R JR; Liu, Guang G; Germano, Peter P; Roux, Julien J; Shea, Courtney M CM; Buys, Emmanuel S ES; Jones, Juli E JE
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35308230
Variant Present in the following documents:
  • fphar-13-852080.pdf
View BVdb publication page



The Molecular Brakes of Adipose Tissue Lipolysis.

Frontiers In Physiology
Li, Yongguo Y; Li, Zhen Z; Ngandiri, Devi Anggraini DA; Llerins Perez, Mireia M; Wolf, Alexander A; Wang, Yuanyuan Y
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35283787
Variant Present in the following documents:
  • fphys-13-826314.pdf
View BVdb publication page



Alcohol-Related Elevation of Liver Transaminase Is Associated With Gut Microbiota in Male.

Frontiers In Medicine
Jiao, Mengfan M; Yan, Su S; Shi, Qingmiao Q; Liu, Ying Y; Li, Yaoguang Y; Lv, Jun J; Ding, Suying S; Li, Ang A
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35280887
Variant Present in the following documents:
  • fmed-09-823898.pdf
View BVdb publication page



Interaction between Lifestyle Changes and PNPLA3 Genotype in NAFLD Patients during the COVID-19 Lockdown.

Nutrients
Cinque, Felice F; Cespiati, Annalisa A; Lombardi, Rosa R; Costantino, Andrea A; Maffi, Gabriele G; Alletto, Francesca F; Colavolpe, Lucia L; Francione, Paolo P; Oberti, Giovanna G; Fatta, Erika E; Bertelli, Cristina C; Sigon, Giordano G; Dongiovanni, Paola P; Vecchi, Maurizio M; Fargion, Silvia S; Fracanzani, Anna Ludovica AL
Publication Date: 2022-01-27

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35276911
Variant Present in the following documents:
  • nutrients-14-00556.pdf
View BVdb publication page



Synergistic and Detrimental Effects of Alcohol Intake on Progression of Liver Steatosis.

International Journal Of Molecular Sciences
Di Ciaula, Agostino A; Bonfrate, Leonilde L; Krawczyk, Marcin M; Frühbeck, Gema G; Portincasa, Piero P
Publication Date: 2022-02-27

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35269779
Variant Present in the following documents:
  • ijms-23-02636.pdf
View BVdb publication page



The Coexistence of Nonalcoholic Fatty Liver Disease and Type 2 Diabetes Mellitus.

Journal Of Clinical Medicine
Kosmalski, Marcin M; Ziółkowska, Sylwia S; Czarny, Piotr P; Szemraj, Janusz J; Pietras, Tadeusz T
Publication Date: 2022-03-02

Variant appearance in text: adiponutrin: I148M
PubMed Link: 35268466
Variant Present in the following documents:
  • jcm-11-01375.pdf
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Dose-Response Associations of Metabolic Score for Insulin Resistance Index with Nonalcoholic Fatty Liver Disease among a Nonobese Chinese Population: Retrospective Evidence from a Population-Based Cohort Study.

Disease Markers
Cai, Xintian X; Gao, Jing J; Hu, Junli J; Wen, Wen W; Zhu, Qing Q; Wang, Mengru M; Liu, Shasha S; Hong, Jing J; Wu, Ting T; Yang, Shunfan S; Tuerxun, Guzailinuer G; Li, Nanfang N
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35251371
Variant Present in the following documents:
  • DM2022-4930355.pdf
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Platelets in Non-alcoholic Fatty Liver Disease.

Frontiers In Pharmacology
Dalbeni, Andrea A; Castelli, Marco M; Zoncapè, Mirko M; Minuz, Pietro P; Sacerdoti, David D
Publication Date: 2022

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35250588
Variant Present in the following documents:
  • fphar-13-842636.pdf
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Activation of Liver mTORC1 Protects Against NASH via Dual Regulation of VLDL-TAG Secretion and De Novo Lipogenesis.

Cellular And Molecular Gastroenterology And Hepatology
Uehara, Kahealani K; Sostre-Colón, Jaimarie J; Gavin, Matthew M; Santoleri, Dominic D; Leonard, Kelly-Ann KA; Jacobs, René L RL; Titchenell, Paul M PM
Publication Date: 2022-02-28

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35240344
Variant Present in the following documents:
  • main.pdf
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Blood lipid metabolism and the risk of gallstone disease: a multi-center study and meta-analysis.

Lipids In Health And Disease
Zhang, Min M; Mao, Min M; Zhang, Chi C; Hu, Fulan F; Cui, Ping P; Li, Guangcan G; Shi, Jia J; Wang, Xin X; Shan, Xuefeng X
Publication Date: 2022-03-02

Variant appearance in text: adiponutrin: I148M
PubMed Link: 35236330
Variant Present in the following documents:
  • 12944_2022_Article_1635.pdf
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Influence of Nonalcoholic Fatty Liver Disease on the Occurrence and Severity of Chronic Kidney Disease.

Journal Of Clinical And Translational Hepatology
Tao, Ziwen Z; Li, Yueyue Y; Cheng, Baoquan B; Zhou, Tao T; Gao, Yanjing Y
Publication Date: 2022-02-28

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35233386
Variant Present in the following documents:
  • JCTH-10-164.pdf
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Non-Alcoholic Fatty Liver Disease and Risk of Macro- and Microvascular Complications in Patients with Type 2 Diabetes.

Journal Of Clinical Medicine
Mantovani, Alessandro A; Dalbeni, Andrea A; Beatrice, Giorgia G; Cappelli, Davide D; Gomez-Peralta, Fernando F
Publication Date: 2022-02-12

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35207239
Variant Present in the following documents:
  • jcm-11-00968.pdf
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Diagnostic Modalities of Non-Alcoholic Fatty Liver Disease: From Biochemical Biomarkers to Multi-Omics Non-Invasive Approaches.

Diagnostics (Basel, Switzerland)
Martinou, Eirini E; Pericleous, Marinos M; Stefanova, Irena I; Kaur, Vasha V; Angelidi, Angeliki M AM
Publication Date: 2022-02-04

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35204498
Variant Present in the following documents:
  • diagnostics-12-00407.pdf
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Nutrigenetics, omega-3 and plasma lipids/lipoproteins/apolipoproteins with evidence evaluation using the GRADE approach: a systematic review.

Bmj Open
Keathley, Justine J; Garneau, Véronique V; Marcil, Valérie V; Mutch, David M DM; Robitaille, Julie J; Rudkowska, Iwona I; Sofian, Gabriela Magdalena GM; Desroches, Sophie S; Vohl, Marie-Claude MC
Publication Date: 2022-02-22

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35193914
Variant Present in the following documents:
  • bmjopen-2021-054417supp001.pdf
  • bmjopen-2021-054417.draft_revisions.pdf
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Multi-Trait Genome-Wide Association Study of Atherosclerosis Detects Novel Pleiotropic Loci.

Frontiers In Genetics
Bellomo, Tiffany R TR; Bone, William P WP; Chen, Brian Y BY; Gawronski, Katerina A B KAB; Zhang, David D; Park, Joseph J; Levin, Michael M; Tsao, Noah N; Klarin, Derek D; Lynch, Julie J; Assimes, Themistocles L TL; Gaziano, J Michael JM; Wilson, Peter W PW; Cho, Kelly K; Vujkovic, Marijana M; O'Donnell, Christopher J CJ; Chang, Kyong-Mi KM; Tsao, Philip S PS; Rader, Daniel J DJ; Ritchie, Marylyn D MD; Damrauer, Scott M SM; Voight, Benjamin F BF
Publication Date: 2021

Variant appearance in text: rs738409
PubMed Link: 35186008
Variant Present in the following documents:
  • fgene-12-787545.pdf
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Efficacy of Lipid Ratios and Platelet Distribution Width for Assessment of Liver Fibrosis in Patients With Non-alcoholic Fatty Liver Disease.

Cureus
Kumari, Bandana B; Sharma, Sadhana S; Kumar, Ramesh R; Dipankar, Satish S; Naik, Bijaya N BN; Banerjee, Ayan A; Kumar, Sushil S
Publication Date: 2022-01

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35165568
Variant Present in the following documents:
  • cureus-0014-00000021110.pdf
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Potential Genes Associated with COVID-19 and Comorbidity.

International Journal Of Medical Sciences
Feng, Shanshan S; Song, Fuqiang F; Guo, Wenqiong W; Tan, Jishan J; Zhang, Xianqin X; Qiao, Fengling F; Guo, Jinlin J; Zhang, Lin L; Jia, Xu X
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35165525
Variant Present in the following documents:
  • Main text
  • ijmsv19p0402.pdf
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The Association between Serum Uric Acid Levels and 10-Year Cardiovascular Disease Risk in Non-Alcoholic Fatty Liver Disease Patients.

International Journal Of Environmental Research And Public Health
Kim, Kiduk K; Kang, Kyoonho K; Sheol, Hyewon H; Shin, Jihae J; Sim, Youngseo Y; Yang, Taehoon T; Hwang, Jeongwon J; Lee, Ju-Mi JM
Publication Date: 2022-01-18

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35162067
Variant Present in the following documents:
  • ijerph-19-01042.pdf
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Effects of Moderate Alcohol Consumption in Non-Alcoholic Fatty Liver Disease.

Journal Of Clinical Medicine
Lemmer, Peter P; Manka, Paul P; Best, Jan J; Kahraman, Alisan A; Kälsch, Julia J; Vilchez-Vargas, Ramiro R; Link, Alexander A; Chiang, Hsin H; Gerken, Guido G; Canbay, Ali A; Bechmann, Lars P LP; Sydor, Svenja S
Publication Date: 2022-02-08

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35160340
Variant Present in the following documents:
  • jcm-11-00890.pdf
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Single Nucleotide Polymorphism of Genes Associated with Metabolic Fatty Liver Disease.

Journal Of Oncology
Mu, Tong T; Peng, Linrui L; Xie, Xinglei X; He, He H; Shao, Qing Q; Wang, Xiran X; Zhang, Yuwei Y
Publication Date: 2022

Variant appearance in text: rs738409
PubMed Link: 35154322
Variant Present in the following documents:
  • Main text
  • JO2022-9282557.pdf
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Lactiplantibacillus plantarum AR113 Exhibit Accelerated Liver Regeneration by Regulating Gut Microbiota and Plasma Glycerophospholipid.

Frontiers In Microbiology
Xie, Chunliang C; Zhang, Zhoumei Z; Yang, Manyi M; Cao, Cha C; Zhou, Yingjun Y; Zhu, Zuohua Z; Gong, Wenbing W; Xu, Chao C; Yan, Li L; Hu, Zhenxiu Z; Ai, Lianzhong L; Peng, Yuande Y
Publication Date: 2021

Variant appearance in text: rs738409
PubMed Link: 35154031
Variant Present in the following documents:
  • fmicb-12-800470.pdf
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A Genetic and Metabolic Staging System for Predicting the Outcome of Nonalcoholic Fatty Liver Disease.

Hepatology Communications
Pennisi, Grazia G; Pipitone, Rosaria Maria RM; Enea, Marco M; De Vincentis, Antonio A; Battaglia, Salvatore S; Di Marco, Vito V; Di Martino, Vincenzo V; Spatola, Federica F; Tavaglione, Federica F; Vespasiani-Gentilucci, Umberto U; Zito, Rossella R; Romeo, Stefano S; Cammà, Calogero C; Craxì, Antonio A; Grimaudo, Stefania S; Petta, Salvatore S
Publication Date: 2022-02-11

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35146945
Variant Present in the following documents:
  • HEP4-6-1032.pdf
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Comprehensive Comparative Analysis of Standard Validated, Genetic, and Novel Biomarkers to Enhance Prognostic Risk-stratification in Patients with Hepatitis C Cirrhosis.

Clinical And Translational Gastroenterology
Innes, Hamish H; Walker, Alex J AJ; Benselin, Jennifer J; Grove, Jane I JI; Pedergnana, Vincent V; Lin, Shang-Kuan SK; McLauchlan, John J; Hutchinson, Sharon J SJ; Barnes, Eleanor E; Irving, William L WL; Guha, Indra Neil IN; , ; , ; , ; ,
Publication Date: 2022-02-09

Variant appearance in text: rs738409
PubMed Link: 35142723
Variant Present in the following documents:
  • ct9-13-e00462.pdf
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Genome-wide association meta-analysis identifies 29 new acne susceptibility loci.

Nature Communications
Mitchell, Brittany L BL; Saklatvala, Jake R JR; Dand, Nick N; Hagenbeek, Fiona A FA; Li, Xin X; Min, Josine L JL; Thomas, Laurent L; Bartels, Meike M; Jan Hottenga, Jouke J; Lupton, Michelle K MK; Boomsma, Dorret I DI; Dong, Xianjun X; Hveem, Kristian K; Løset, Mari M; Martin, Nicholas G NG; Barker, Jonathan N JN; Han, Jiali J; Smith, Catherine H CH; Rentería, Miguel E ME; Simpson, Michael A MA
Publication Date: 2022-02-07

Variant appearance in text: rs738409
PubMed Link: 35132056
Variant Present in the following documents:
  • Main text
  • 41467_2022_28252_MOESM1_ESM.pdf
  • 41467_2022_Article_28252.pdf
View BVdb publication page



Multiomics Analysis Reveals the Impact of Microbiota on Host Metabolism in Hepatic Steatosis.

Advanced Science (Weinheim, Baden-Wurttemberg, Germany)
Zeybel, Mujdat M; Arif, Muhammad M; Li, Xiangyu X; Altay, Ozlem O; Yang, Hong H; Shi, Mengnan M; Akyildiz, Murat M; Saglam, Burcin B; Gonenli, Mehmet Gokhan MG; Yigit, Buket B; Ulukan, Burge B; Ural, Dilek D; Shoaie, Saeed S; Turkez, Hasan H; Nielsen, Jens J; Zhang, Cheng C; Uhlén, Mathias M; Borén, Jan J; Mardinoglu, Adil A
Publication Date: 2022-02-07

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35128832
Variant Present in the following documents:
  • ADVS-9-2104373.pdf
View BVdb publication page



Is there a role of lipid-lowering therapies in the management of fatty liver disease?

World Journal Of Hepatology
Tzanaki, Ismini I; Agouridis, Aris P AP; Kostapanos, Michael S MS
Publication Date: 2022-01-27

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35126843
Variant Present in the following documents:
  • WJH-14-119.pdf
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Factors That Predict the Progression of Non-alcoholic Fatty Liver Disease (NAFLD).

Cureus
Parameswaran, Madhangi M; Hasan, Hamzah A HA; Sadeque, Jafor J; Jhaveri, Sharan S; Avanthika, Chaithanya C; Arisoyin, Abimbola E AE; Dhanani, Maulik B MB; Rath, Swaroopa M SM
Publication Date: 2021-12

Variant appearance in text: rs738409
PubMed Link: 35111461
Variant Present in the following documents:
  • Main text
  • cureus-0013-00000020776.pdf
View BVdb publication page



Non-alcoholic fatty liver disease and hepatocellular carcinoma: Clinical challenges of an intriguing link.

World Journal Of Gastroenterology
Chrysavgis, Lampros L; Giannakodimos, Ilias I; Diamantopoulou, Panagiota P; Cholongitas, Evangelos E
Publication Date: 2022-01-21

Variant appearance in text: rs738409
PubMed Link: 35110952
Variant Present in the following documents:
  • Main text
  • WJG-28-310.pdf
View BVdb publication page



PSD3 downregulation confers protection against fatty liver disease.

Nature Metabolism
Mancina, Rosellina M RM; Sasidharan, Kavitha K; Lindblom, Anna A; Wei, Ying Y; Ciociola, Ester E; Jamialahmadi, Oveis O; Pingitore, Piero P; Andréasson, Anne-Christine AC; Pellegrini, Giovanni G; Baselli, Guido G; Männistö, Ville V; Pihlajamäki, Jussi J; Kärjä, Vesa V; Grimaudo, Stefania S; Marini, Ilaria I; Maggioni, Marco M; Becattini, Barbara B; Tavaglione, Federica F; Dix, Carly C; Castaldo, Marie M; Klein, Stephanie S; Perelis, Mark M; Pattou, Francois F; Thuillier, Dorothée D; Raverdy, Violeta V; Dongiovanni, Paola P; Fracanzani, Anna Ludovica AL; Stickel, Felix F; Hampe, Jochen J; Buch, Stephan S; Luukkonen, Panu K PK; Prati, Daniele D; Yki-Järvinen, Hannele H; Petta, Salvatore S; Xing, Chao C; Schafmayer, Clemens C; Aigner, Elmar E; Datz, Christian C; Lee, Richard G RG; Valenti, Luca L; Lindén, Daniel D; Romeo, Stefano S
Publication Date: 2022-01

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35102341
Variant Present in the following documents:
  • Main text
  • 42255_2021_Article_518.pdf
  • 42255_2021_518_MOESM1_ESM.pdf
View BVdb publication page



KIAA1363 affects retinyl ester turnover in cultured murine and human hepatic stellate cells.

Journal Of Lipid Research
Wagner, Carina C; Hois, Victoria V; Eggeling, Annalena A; Pusch, Lisa-Maria LM; Pajed, Laura L; Starlinger, Patrick P; Claudel, Thierry T; Trauner, Michael M; Zimmermann, Robert R; Taschler, Ulrike U; Lass, Achim A
Publication Date: 2022-01-28

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35101424
Variant Present in the following documents:
  • main.pdf
View BVdb publication page



Genetic and Life Style Risk Factors for Recurrent Non-alcoholic Fatty Liver Disease Following Liver Transplantation.

Frontiers In Nutrition
Iacob, Speranta S; Beckebaum, Susanne S; Iacob, Razvan R; Gheorghe, Cristian C; Cicinnati, Vito V; Popescu, Irinel I; Gheorghe, Liana L
Publication Date: 2021

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35096933
Variant Present in the following documents:
  • fnut-08-787430.pdf
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MAFLD/NAFLD Biopsy-Free Scoring Systems for Hepatic Steatosis, NASH, and Fibrosis Diagnosis.

Frontiers In Medicine
Segura-Azuara, Nancy de Los Ángeles NLÁ; Varela-Chinchilla, Carlos Daniel CD; Trinidad-Calderón, Plinio A PA
Publication Date: 2021

Variant appearance in text: rs738409
PubMed Link: 35096868
Variant Present in the following documents:
  • fmed-08-774079.pdf
View BVdb publication page



Gut microbiota in patients with obesity and metabolic disorders - a systematic review.

Genes & Nutrition
Xu, Zhilu Z; Jiang, Wei W; Huang, Wenli W; Lin, Yu Y; Chan, Francis K L FKL; Ng, Siew C SC
Publication Date: 2022-01-29

Variant appearance in text: rs738409
PubMed Link: 35093025
Variant Present in the following documents:
  • 12263_2021_Article_703.pdf
View BVdb publication page



The influence of host genetics on liver microbiome composition in patients with NAFLD.

Ebiomedicine
Pirola, Carlos Jose CJ; Salatino, Adrian A; Quintanilla, Maria Florencia MF; Castaño, Gustavo Osvaldo GO; Garaycoechea, Martin M; Sookoian, Silvia S
Publication Date: 2022-01-26

Variant appearance in text: rs738409
PubMed Link: 35092912
Variant Present in the following documents:
  • Main text
  • main.pdf
View BVdb publication page



Liver Fibrosis-From Mechanisms of Injury to Modulation of Disease.

Frontiers In Medicine
Liedtke, Christian C; Nevzorova, Yulia A YA; Luedde, Tom T; Zimmermann, Henning H; Kroy, Daniela D; Strnad, Pavel P; Berres, Marie-Luise ML; Bernhagen, Jürgen J; Tacke, Frank F; Nattermann, Jacob J; Spengler, Ulrich U; Sauerbruch, Tilman T; Wree, Alexander A; Abdullah, Zeinab Z; Tolba, René H RH; Trebicka, Jonel J; Lammers, Twan T; Trautwein, Christian C; Weiskirchen, Ralf R
Publication Date: 2021

Variant appearance in text: PNPLA3: I148M
PubMed Link: 35087852
Variant Present in the following documents:
  • Main text
View BVdb publication page



Hepatic Unsaturated Fatty Acids Are Linked to Lower Degree of Fibrosis in Non-alcoholic Fatty Liver Disease.

Frontiers In Medicine
Fridén, Michael M; Rosqvist, Fredrik F; Ahlström, Håkan H; Niessen, Heiko G HG; Schultheis, Christian C; Hockings, Paul P; Hulthe, Johannes J; Gummesson, Anders A; Wanders, Alkwin A; Rorsman, Fredrik F; Risérus, Ulf U; Vessby, Johan J
Publication Date: 2021

Variant appearance in text: PNPLA3: I148M; rs738409
PubMed Link: 35083257
Variant Present in the following documents:
  • Main text
  • fmed-08-814951.pdf
View BVdb publication page