SI c.773_774delinsTT ;(p.W258F)

Variant ID: 3-164783082-CC-AA

NM_001041.3(SI):c.773_774delinsTT;(p.W258F)

This variant was identified in 5 publications

View GRCh38 version.




Publications:


Receptor tyrosine kinases activate heterotrimeric G proteins via phosphorylation within the interdomain cleft of Gαi.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Kalogriopoulos, Nicholas A NA; Lopez-Sanchez, Inmaculada I; Lin, Changsheng C; Ngo, Tony T; Midde, Krishna K KK; Roy, Suchismita S; Aznar, Nicolas N; Murray, Fiona F; Garcia-Marcos, Mikel M; Kufareva, Irina I; Ghassemian, Majid M; Ghosh, Pradipta P
Publication Date: 2020-11-17

Variant appearance in text: SI: W258F
PubMed Link: 33139573
Variant Present in the following documents:
  • Main text
View BVdb publication page



Activation of G proteins by GIV-GEF is a pivot point for insulin resistance and sensitivity.

Molecular Biology Of The Cell
Ma, Gary S GS; Lopez-Sanchez, Inmaculada I; Aznar, Nicolas N; Kalogriopoulos, Nicholas N; Pedram, Shabnam S; Midde, Krishna K; Ciaraldi, Theodore P TP; Henry, Robert R RR; Ghosh, Pradipta P
Publication Date: 2015-11-15

Variant appearance in text: SI: W258F
PubMed Link: 26378251
Variant Present in the following documents:
  • 4209.pdf
View BVdb publication page



Multimodular biosensors reveal a novel platform for activation of G proteins by growth factor receptors.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Midde, Krishna K KK; Aznar, Nicolas N; Laederich, Melanie B MB; Ma, Gary S GS; Kunkel, Maya T MT; Newton, Alexandra C AC; Ghosh, Pradipta P
Publication Date: 2015-03-03

Variant appearance in text: SI: W258F
PubMed Link: 25713130
Variant Present in the following documents:
  • Main text
View BVdb publication page



Contribution of each Trp residue toward the intrinsic fluorescence of the Giα1 protein.

Protein Science : A Publication Of The Protein Society
Najor, Matthew S MS; Olsen, Kenneth W KW; Graham, Daniel J DJ; Mota de Freitas, Duarte D
Publication Date: 2014-10

Variant appearance in text: SI: W258F
PubMed Link: 25044474
Variant Present in the following documents:
  • Main text
View BVdb publication page



Functional characterization of the guanine nucleotide exchange factor (GEF) motif of GIV protein reveals a threshold effect in signaling.

Proceedings Of The National Academy Of Sciences Of The United States Of America
Garcia-Marcos, Mikel M; Kietrsunthorn, Patrick S PS; Pavlova, Yelena Y; Adia, Michelle A MA; Ghosh, Pradipta P; Farquhar, Marilyn G MG
Publication Date: 2012-02-07

Variant appearance in text: SI: W258F
PubMed Link: 22308453
Variant Present in the following documents:
  • Main text
View BVdb publication page