Disordered clusters of Bak dimers rupture mitochondria during apoptosis.
Elife
Uren, Rachel T RT; O'Hely, Martin M; Iyer, Sweta S; Bartolo, Ray R; Shi, Melissa X MX; Brouwer, Jason M JM; Alsop, Amber E AE; Dewson, Grant G; Kluck, Ruth M RM
Apoptotic pore formation is associated with in-plane insertion of Bak or Bax central helices into the mitochondrial outer membrane.
Proceedings Of The National Academy Of Sciences Of The United States Of America
Westphal, Dana D; Dewson, Grant G; Menard, Marie M; Frederick, Paul P; Iyer, Sweta S; Bartolo, Ray R; Gibson, Leonie L; Czabotar, Peter E PE; Smith, Brian J BJ; Adams, Jerry M JM; Kluck, Ruth M RM