Durvalumab plus tremelimumab for the treatment of advanced neuroendocrine neoplasms of gastroenteropancreatic and lung origin.
Nature Communications
Capdevila, J J; Hernando, J J; Teule, A A; Lopez, C C; Garcia-Carbonero, R R; Benavent, M M; Custodio, A A; Garcia-Alvarez, A A; Cubillo, A A; Alonso, V V; Carmona-Bayonas, A A; Alonso-Gordoa, T T; Crespo, G G; Jimenez-Fonseca, P P; Blanco, M M; Viudez, A A; La Casta, A A; Sevilla, I I; Segura, A A; Llanos, M M; Landolfi, S S; Nuciforo, P P; Manzano, J L JL
Induction chemoimmunotherapy followed by CD8+ immune cell-based patient selection for chemotherapy-free radioimmunotherapy in locally advanced head and neck cancer.
Journal For Immunotherapy Of Cancer
Hecht, Markus M; Eckstein, Markus M; Rutzner, Sandra S; von der Grün, Jens J; Illmer, Thomas T; Klautke, Gunther G; Laban, Simon S; Hautmann, Matthias G MG; Brunner, Thomas B TB; Tamaskovics, Bálint B; Hinke, Axel A; Zhou, Jian-Guo JG; Frey, Benjamin B; Donaubauer, Anna-Jasmina AJ; Becker, Ina I; Semrau, Sabine S; Hartmann, Arndt A; Balermpas, Panagiotis P; Budach, Wilfried W; Gaipl, Udo S US; Iro, Heinrich H; Gostian, Antoniu-Oreste AO; Fietkau, Rainer R
Combined CTLA-4 and PD-L1 blockade in patients with chemotherapy-naïve metastatic castration-resistant prostate cancer is associated with increased myeloid and neutrophil immune subsets in the bone microenvironment.
Journal For Immunotherapy Of Cancer
Subudhi, Sumit K SK; Siddiqui, Bilal A BA; Aparicio, Ana M AM; Yadav, Shalini S SS; Basu, Sreyashi S; Chen, Hong H; Jindal, Sonali S; Tidwell, Rebecca S S RSS; Varma, Ashwin A; Logothetis, Christopher J CJ; Allison, James P JP; Corn, Paul G PG; Sharma, Padmanee P
Ensemble-based enzyme design can recapitulate the effects of laboratory directed evolution in silico.
Nature Communications
Broom, Aron A; Rakotoharisoa, Rojo V RV; Thompson, Michael C MC; Zarifi, Niayesh N; Nguyen, Erin E; Mukhametzhanov, Nurzhan N; Liu, Lin L; Fraser, James S JS; Chica, Roberto A RA