Machine learning-driven identification of drugs inhibiting cytochrome P450 2C9.
Plos Computational Biology
Goldwaser, Elodie E; Laurent, Catherine C; Lagarde, Nathalie N; Fabrega, Sylvie S; Nay, Laure L; Villoutreix, Bruno O BO; Jelsch, Christian C; Nicot, Arnaud B AB; Loriot, Marie-Anne MA; Miteva, Maria A MA
Transcriptomic, proteomic, and metabolomic analyses identify candidate pathways linking maternal cadmium exposure to altered neurodevelopment and behavior.
Scientific Reports
Hudson, Kathleen M KM; Shiver, Emily E; Yu, Jianshi J; Mehta, Sanya S; Jima, Dereje D DD; Kane, Maureen A MA; Patisaul, Heather B HB; Cowley, Michael M
A human-airway-on-a-chip for the rapid identification of candidate antiviral therapeutics and prophylactics.
Nature Biomedical Engineering
Si, Longlong L; Bai, Haiqing H; Rodas, Melissa M; Cao, Wuji W; Oh, Crystal Yuri CY; Jiang, Amanda A; Moller, Rasmus R; Hoagland, Daisy D; Oishi, Kohei K; Horiuchi, Shu S; Uhl, Skyler S; Blanco-Melo, Daniel D; Albrecht, Randy A RA; Liu, Wen-Chun WC; Jordan, Tristan T; Nilsson-Payant, Benjamin E BE; Golynker, Ilona I; Frere, Justin J; Logue, James J; Haupt, Robert R; McGrath, Marisa M; Weston, Stuart S; Zhang, Tian T; Plebani, Roberto R; Soong, Mercy M; Nurani, Atiq A; Kim, Seong Min SM; Zhu, Danni Y DY; Benam, Kambez H KH; Goyal, Girija G; Gilpin, Sarah E SE; Prantil-Baun, Rachelle R; Gygi, Steven P SP; Powers, Rani K RK; Carlson, Kenneth E KE; Frieman, Matthew M; tenOever, Benjamin R BR; Ingber, Donald E DE
HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice.
Cell Death And Differentiation
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HDAC inhibition ameliorates cone survival in retinitis pigmentosa mice.
Cell Death And Differentiation
Samardzija, Marijana M; Corna, Andrea A; Gomez-Sintes, Raquel R; Jarboui, Mohamed Ali MA; Armento, Angela A; Roger, Jerome E JE; Petridou, Eleni E; Haq, Wadood W; Paquet-Durand, Francois F; Zrenner, Eberhart E; de la Villa, Pedro P; Zeck, Günther G; Grimm, Christian C; Boya, Patricia P; Ueffing, Marius M; Trifunović, Dragana D
Orally efficacious broad-spectrum allosteric inhibitor of paramyxovirus polymerase.
Nature Microbiology
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