Publications:

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Genetic variations in the PI3K/PTEN/AKT/mTOR pathway predict tumor response and disease-free survival in locally advanced rectal cancer patients receiving preoperative chemoradiotherapy and radical surgery.

Journal Of Cancer

Peng, Jianhong J; Ma, Wenjuan W; Zhou, Zhongguo Z; Gu, Yangkui Y; Lu, Zhenhai Z; Zhang, Rongxin R; Pan, Zhizhong Z

Publication Date: 2018

Variant appearance in text: rs7651265

PubMed Link: 29581786

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• Main text

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Association between single nucleotide polymorphisms in the PI3K/AKT/mTOR pathway and bladder cancer risk in a sample of Iranian population.

Excli Journal

Bizhani, Fatemeh F; Hashemi, Mohammad M; Danesh, Hiva H; Nouralizadeh, Akbar A; Narouie, Behzad B; Bahari, Gholamreza G; Ghavami, Saeid S

Publication Date: 2018

Variant appearance in text: rs7651265

PubMed Link: 29383014

Variant Present in the following documents:

• Main text
• EXCLI-17-3.pdf

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Functional PTGS2 polymorphism-based models as novel predictive markers in metastatic renal cell carcinoma patients receiving first-line sunitinib.

Scientific Reports

Cebrián, Arancha A; Gómez Del Pulgar, Teresa T; Méndez-Vidal, María José MJ; Gonzálvez, María Luisa ML; Lainez, Nuria N; Castellano, Daniel D; García-Carbonero, Iciar I; Esteban, Emilio E; Sáez, Maria Isabel MI; Villatoro, Rosa R; Suárez, Cristina C; Carrato, Alfredo A; Munárriz-Ferrándiz, Javier J; Basterrechea, Laura L; García-Alonso, Mirta M; González-Larriba, José Luis JL; Perez-Valderrama, Begoña B; Cruz-Jurado, Josefina J; González Del Alba, Aránzazu A; Moreno, Fernando F; Reynés, Gaspar G; Rodríguez-Remírez, María M; Boni, Valentina V; Mahillo-Fernández, Ignacio I; Martin, Yolanda Y; Viqueira, Andrea A; García-Foncillas, Jesús J

Publication Date: 2017-01-24

Variant appearance in text: rs7651265

PubMed Link: 28117391

Variant Present in the following documents:

• Main text
• srep41371.pdf

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Sirolimus and Everolimus Pathway: Reviewing Candidate Genes Influencing Their Intracellular Effects.

International Journal Of Molecular Sciences

Granata, Simona S; Dalla Gassa, Alessandra A; Carraro, Amedeo A; Brunelli, Matteo M; Stallone, Giovanni G; Lupo, Antonio A; Zaza, Gianluigi G

Publication Date: 2016-05-14

Variant appearance in text: rs7651265

PubMed Link: 27187382

Variant Present in the following documents:

• Main text
• ijms-17-00735.pdf

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Genetic association between PIK3CA gene and oral squamous cell carcinoma: a case control study conducted in Chongqing, China.

International Journal Of Clinical And Experimental Pathology

Wan, Xiaoxiao X; Li, Xian X; Yang, Junyan J; Lv, Wei W; Wang, Qiming Q; Chen, Ying Y; Li, Yong Y

Publication Date: 2015

Variant appearance in text: rs7651265

PubMed Link: 26722541

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Associations of PI3KR1 and mTOR polymorphisms with esophageal squamous cell carcinoma risk and gene-environment interactions in Eastern Chinese populations.

Scientific Reports

Zhu, Jinhong J; Wang, Mengyun M; Zhu, Meiling M; He, Jin J; Wang, Jiu-Cun JC; Jin, Li L; Wang, Xiao-Feng XF; Xiang, Jia-Qing JQ; Wei, Qingyi Q

Publication Date: 2015-02-05

Variant appearance in text: rs7651265

PubMed Link: 25654238

Variant Present in the following documents:

• Main text

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A pathway approach to evaluating the association between the CHIEF pathway and risk of colorectal cancer.

Carcinogenesis

Slattery, Martha L ML; Wolff, Roger K RK; Lundgreen, Abbie A

Publication Date: 2015-01

Variant appearance in text: rs7651265

PubMed Link: 25330801

Variant Present in the following documents:

• Main text

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Influence of CHIEF pathway genes on gene expression: a pathway approach to functionality.

International Journal Of Molecular Epidemiology And Genetics

Slattery, Martha L ML; Lundgreen, Abbie A; Mullany, Lila E LE; Penney, Rosalind B RB; Wolff, Roger K RK

Publication Date: 2014

Variant appearance in text: rs7651265

PubMed Link: 24959314

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Genetic variants of EGF and VEGF predict prognosis of patients with advanced esophageal squamous cell carcinoma.

Plos One

Yang, Pei-Wen PW; Hsieh, Min-Shu MS; Huang, Ya-Chuan YC; Hsieh, Ching-Yueh CY; Chiang, Tzu-Hsuan TH; Lee, Jang-Ming JM

Publication Date: 2014

Variant appearance in text: rs7651265

PubMed Link: 24945674

Variant Present in the following documents:

• Main text
• pone.0100326.pdf

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Diet and colorectal cancer: analysis of a candidate pathway using SNPS, haplotypes, and multi-gene assessment.

Nutrition And Cancer

Slattery, Martha L ML; Lundgreen, Abbie A; Herrick, Jennifer S JS; Caan, Bette J BJ; Potter, John D JD; Wolff, Roger K RK

Publication Date: 2011-11

Variant appearance in text: rs7651265

PubMed Link: 21999454

Variant Present in the following documents:

• Main text

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Replication of association of a novel insulin receptor gene polymorphism with polycystic ovary syndrome.

Fertility And Sterility

Goodarzi, Mark O MO; Louwers, Yvonne V YV; Taylor, Kent D KD; Jones, Michelle R MR; Cui, Jinrui J; Kwon, Soonil S; Chen, Yii-Der I YD; Guo, Xiuqing X; Stolk, Lisette L; Uitterlinden, André G AG; Laven, Joop S E JS; Azziz, Ricardo R

Publication Date: 2011-04

Variant appearance in text: rs7651265

PubMed Link: 21300347

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• Main text

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Endometrial cancer and genetic variation in PTEN, PIK3CA, AKT1, MLH1, and MSH2 within a population-based case-control study.

Gynecologic Oncology

Lacey, James V JV; Yang, Hannah H; Gaudet, Mia M MM; Dunning, Alison A; Lissowska, Jolanta J; Sherman, Mark E ME; Peplonska, Beata B; Brinton, Louise A LA; Healey, Catherine S CS; Ahmed, Shahana S; Pharoah, Paul P; Easton, Douglas D; Chanock, Stephen S; Garcia-Closas, Montserrat M

Publication Date: 2011-02

Variant appearance in text: rs7651265

PubMed Link: 21093899

Variant Present in the following documents:

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Genetic variation in a metabolic signaling pathway and colon and rectal cancer risk: mTOR, PTEN, STK11, RPKAA1, PRKAG2, TSC1, TSC2, PI3K and Akt1.

Carcinogenesis

Slattery, Martha L ML; Herrick, Jennifer S JS; Lundgreen, Abbie A; Fitzpatrick, Francis A FA; Curtin, Karen K; Wolff, Roger K RK

Publication Date: 2010-09

Variant appearance in text: rs7651265

PubMed Link: 20622004

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PI3K/PTEN/AKT/mTOR pathway genetic variation predicts toxicity and distant progression in lung cancer patients receiving platinum-based chemotherapy.

Lung Cancer (Amsterdam, Netherlands)

Pu, Xia X; Hildebrandt, Michelle A T MA; Lu, Charles C; Lin, Jie J; Stewart, David J DJ; Ye, Yuanqing Y; Gu, Jian J; Spitz, Margaret R MR; Wu, Xifeng X

Publication Date: 2011-01

Variant appearance in text: rs7651265

PubMed Link: 20447721

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Tagging single-nucleotide polymorphisms in candidate oncogenes and susceptibility to ovarian cancer.

British Journal Of Cancer

Quaye, L L; Song, H H; Ramus, S J SJ; Gentry-Maharaj, A A; Høgdall, E E; DiCioccio, R A RA; McGuire, V V; Wu, A H AH; Van Den Berg, D J DJ; Pike, M C MC; Wozniak, E E; Doherty, J A JA; Rossing, M A MA; Ness, R B RB; Moysich, K B KB; Høgdall, C C; Blaakaer, J J; , ; Easton, D F DF; Ponder, B A J BA; Jacobs, I J IJ; Menon, U U; Whittemore, A S AS; Krüger-Kjaer, S S; Pearce, C L CL; Pharoah, P D P PD; Gayther, S A SA

Publication Date: 2009-03-24

Variant appearance in text: rs7651265

PubMed Link: 19240718

Variant Present in the following documents:

• Main text
• 6604947a.pdf

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Genetic variations in the PI3K/PTEN/AKT/mTOR pathway are associated with clinical outcomes in esophageal cancer patients treated with chemoradiotherapy.

Journal Of Clinical Oncology : Official Journal Of The American Society Of Clinical Oncology

Hildebrandt, Michelle A T MA; Yang, Hushan H; Hung, Mien-Chie MC; Izzo, Julie G JG; Huang, Maosheng M; Lin, Jie J; Ajani, Jaffer A JA; Wu, Xifeng X

Publication Date: 2009-02-20

Variant appearance in text: rs7651265

PubMed Link: 19164214

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• Main text

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