Publications:

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Adjustable extracellular matrix rigidity tumor model for studying stiffness dependent pancreatic ductal adenocarcinomas progression and tumor immunosuppression.

Bioengineering & Translational Medicine

Zhang, Haoxiang H; Chen, Jiaoshun J; Hu, Xiaoqing X; Bai, Jianwei J; Yin, Tao T

Publication Date: 2023-05

Variant appearance in text: PI3K: G12V

PubMed Link: 37206224

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• Main text
• BTM2-8-e10518.pdf

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Experimental Murine Models for Colorectal Cancer Research.

Cancers

Neto, Íris Í; Rocha, João J; Gaspar, Maria Manuela MM; Reis, Catarina P CP

Publication Date: 2023-04-30

Variant appearance in text: PIK3CA: G12V

PubMed Link: 37174036

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• Main text

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PI3K Functions Downstream of Cdc42 to Drive Cancer phenotypes in a Melanoma Cell Line.

Small Gtpases

Poku, Rosemary R; Amissah, Felix F; Alan, Jamie K JK

Publication Date: 2023-12

Variant appearance in text: PI3K: G12V

PubMed Link: 37114375

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• Main text
• KSGT_14_2202612.pdf

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Senescence-related genes define prognosis, immune contexture, and pharmacological response in gastric cancer.

Aging

Shen, Xiaogang X; Wang, Meng M; Chen, Wenxi W; Xu, Yu Y; Zhou, Qiaoxia Q; Zhu, Tengfei T; Wang, Guoqiang G; Cai, Shangli S; Han, Yusheng Y; Xu, Chunwei C; Wang, Wenxian W; Meng, Lei L; Sun, Hao H

Publication Date: 2023-02-16

Variant appearance in text: PIK3CA: G12V

PubMed Link: 37100457

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• Main text

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Genomic profiling of idiopathic peri-hilar cholangiocarcinoma reveals new targets and mutational pathways.

Scientific Reports

Quinn, Leonard M LM; Haldenby, Sam S; Antzcak, Philip P; Fowler, Anna A; Bullock, Katie K; Kenny, John J; Gilbert, Timothy T; Andrews, Timothy T; Diaz-Nieto, Rafael R; Fenwick, Stephen S; Jones, Robert R; Costello-Goldring, Eithne E; Poston, Graeme G; Greenhalf, William W; Palmer, Daniel D; Malik, Hassan H; Goldring, Chris C

Publication Date: 2023-04-24

Variant appearance in text: PIK3CA: 35G>T; Gly12Val

PubMed Link: 37095160

Variant Present in the following documents:

• 41598_2023_Article_33096.pdf

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KRAS, NRAS, BRAF, and PIK3CA mutation rates, clinicopathological association, and their prognostic value in Iranian colorectal cancer patients.

Journal Of Clinical Laboratory Analysis

Mirzapoor Abbasabadi, Zohreh Z; Hamedi Asl, Dariush D; Rahmani, Babak B; Shahbadori, Rozhin R; Karami, Sara S; Peymani, Amir A; Taghizadeh, Sara S; Samiee Rad, Fatemeh F

Publication Date: 2023-03-17

Variant appearance in text: PIK3CA: G12V

PubMed Link: 36930789

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• Main text

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A Drosophila chemical screen reveals targeting MEK and DGKa mitigates Ras-driven polarity-impaired tumour growth.

Disease Models & Mechanisms

La Marca, John E JE; Ely, Robert W RW; Diepstraten, Sarah T ST; Burke, Peter P; Kelly, Gemma L GL; Humbert, Patrick O PO; Richardson, Helena E HE

Publication Date: 2023-03-02

Variant appearance in text: PI3K: G12V

PubMed Link: 36861754

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Mammary mucinous cystadenocarcinoma with long-term follow-up: molecular information and literature review.

Diagnostic Pathology

Lei, Ting T; Shi, Yong Qiang YQ; Chen, Tong Bing TB

Publication Date: 2023-02-04

Variant appearance in text: PI3K: G12V

PubMed Link: 36737820

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• Main text
• 13000_2023_Article_1302.pdf

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Preclinical Models of Follicular Cell-Derived Thyroid Cancer: An Overview from Cancer Cell Lines to Mouse Models.

Endocrinology And Metabolism (Seoul, Korea)

Jeon, Min Ji MJ; Haugen, Bryan R BR

Publication Date: 2022-12

Variant appearance in text: PIK3CA: G12V

PubMed Link: 36604954

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• Main text
• enm-2022-1636.pdf

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CD46 protects the bladder cancer cells from cetuximab-mediated cytotoxicity.

Scientific Reports

Do, Manh-Hung MH; Thanh, Hien Duong HD; To, Phuong Kim PK; Kim, Min Soo MS; Moon, Changjong C; Jung, Chaeyong C

Publication Date: 2022-12-27

Variant appearance in text: PIK3CA: G12V

PubMed Link: 36575233

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• Main text
• 41598_2022_Article_27107.pdf

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Characterization of mutant versions of the R-RAS2/TC21 GTPase found in tumors.

Oncogene

Clavaín, Laura L; Fernández-Pisonero, Isabel I; Movilla, Nieves N; Lorenzo-Martín, L Francisco LF; Nieto, Blanca B; Abad, Antonio A; García-Navas, Rósula R; Llorente-González, Clara C; Sánchez-Martín, Manuel M; Vicente-Manzanares, Miguel M; Santos, Eugenio E; Alarcón, Balbino B; García-Aznar, José M JM; Dosil, Mercedes M; Bustelo, Xosé R XR

Publication Date: 2022-12-07

Variant appearance in text: PI3K: G12V

PubMed Link: 36476833

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Yap governs a lineage-specific neuregulin1 pathway-driven adaptive resistance to RAF kinase inhibitors.

Molecular Cancer

Garcia-Rendueles, Maria E R MER; Krishnamoorthy, Gnana G; Saqcena, Mahesh M; Acuña-Ruiz, Adrian A; Revilla, Giovanna G; de Stanchina, Elisa E; Knauf, Jeffrey A JA; Lester, Rona R; Xu, Bin B; Ghossein, Ronald A RA; Fagin, James A JA

Publication Date: 2022-12-07

Variant appearance in text: PI3K: G12V

PubMed Link: 36476495

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HRas and Myc synergistically induce cell cycle progression and apoptosis of murine cardiomyocytes.

Frontiers In Cardiovascular Medicine

Boikova, Aleksandra A; Bywater, Megan J MJ; Quaife-Ryan, Gregory A GA; Straube, Jasmin J; Thompson, Lucy L; Ascanelli, Camilla C; Littlewood, Trevor D TD; Evan, Gerard I GI; Hudson, James E JE; Wilson, Catherine H CH

Publication Date: 2022

Variant appearance in text: PI3K: G12V

PubMed Link: 36337898

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Genomic landscape, immune characteristics and prognostic mutation signature of cervical cancer in China.

Bmc Medical Genomics

Liu, Jing J; Li, Zirong Z; Lu, Ting T; Pan, Junping J; Li, Li L; Song, Yanwen Y; Hu, Dan D; Zhuo, Yanhong Y; Chen, Ying Y; Xu, Qin Q

Publication Date: 2022-11-04

Variant appearance in text: PIK3CA: 35G>T

PubMed Link: 36333792

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• 12920_2022_1376_MOESM1_ESM.xlsx, sheet 1

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The mutational landscape of cancer's vulnerability to ionizing radiation.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Gopal, Priyanka P; Yard, Brian D BD; Petty, Aaron A; Lal, Jessica C JC; Bera, Titas K TK; Hoang, Trung Q TQ; Buhimschi, Alexandru B AB; Abazeed, Mohamed E ME

Publication Date: 2022-10-12

Variant appearance in text: PIK3CA: G12V

PubMed Link: 36222846

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• 5343.pdf

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Targeting epiregulin in the treatment-damaged tumor microenvironment restrains therapeutic resistance.

Oncogene

Wang, Changxu C; Long, Qilai Q; Fu, Qiang Q; Xu, Qixia Q; Fu, Da D; Li, Yan Y; Gao, Libin L; Guo, Jianming J; Zhang, Xiaoling X; Lam, Eric W-F EW; Campisi, Judith J; Sun, Yu Y

Publication Date: 2022-11

Variant appearance in text: PIK3CA: G12V

PubMed Link: 36202915

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Mechanistic insights from animal models of neurofibromatosis type 1 cognitive impairment.

Disease Models & Mechanisms

Miller, Andrew H AH; Halloran, Mary C MC

Publication Date: 2022-08-01

Variant appearance in text: PI3K: G12V

PubMed Link: 36037004

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Molecular characterization of colorectal cancer related peritoneal metastatic disease.

Nature Communications

Lenos, Kristiaan J KJ; Bach, Sander S; Ferreira Moreno, Leandro L; Ten Hoorn, Sanne S; Sluiter, Nina R NR; Bootsma, Sanne S; Vieira Braga, Felipe A FA; Nijman, Lisanne E LE; van den Bosch, Tom T; Miedema, Daniel M DM; van Dijk, Erik E; Ylstra, Bauke B; Kulicke, Ruth R; Davis, Fred P FP; Stransky, Nicolas N; Smolen, Gromoslaw A GA; Coebergh van den Braak, Robert R J RRJ; IJzermans, Jan N M JNM; Martens, John W M JWM; Hallam, Sally S; Beggs, Andrew D AD; Kops, Geert J P L GJPL; Lansu, Nico N; Bastiaenen, Vivian P VP; Klaver, Charlotte E L CEL; Lecca, Maria C MC; El Makrini, Khalid K; Elbers, Clara C CC; Dings, Mark P G MPG; van Noesel, Carel J M CJM; Kranenburg, Onno O; Medema, Jan Paul JP; Koster, Jan J; Koens, Lianne L; Punt, Cornelis J A CJA; Tanis, Pieter J PJ; de Hingh, Ignace H IH; Bijlsma, Maarten F MF; Tuynman, Jurriaan B JB; Vermeulen, Louis L

Publication Date: 2022-08-04

Variant appearance in text: PIK3CA: G12V

PubMed Link: 35927254

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• 41467_2022_32198_MOESM4_ESM.xlsx, sheet 1

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Comparing single-target and multitarget approaches for postoperative circulating tumour DNA detection in stage II-III colorectal cancer patients.

Molecular Oncology

Henriksen, Tenna Vesterman TV; Reinert, Thomas T; Rasmussen, Mads Heilskov MH; Demuth, Christina C; Løve, Uffe Schou US; Madsen, Anders Husted AH; Gotschalck, Kåre Andersson KA; Iversen, Lene Hjerrild LH; Andersen, Claus Lindbjerg CL

Publication Date: 2022-10

Variant appearance in text: PIK3CA: 35G>T; G12V

PubMed Link: 35895438

Variant Present in the following documents:

• MOL2-16-3654-s004.xlsx, sheet 1

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Targeting the DNA Damage Response Pathways and Replication Stress in Colorectal Cancer.

Clinical Cancer Research : An Official Journal Of The American Association For Cancer Research

Durinikova, Erika E; Reilly, Nicole M NM; Buzo, Kristi K; Mariella, Elisa E; Chilà, Rosaria R; Lorenzato, Annalisa A; Dias, João M L JML; Grasso, Gaia G; Pisati, Federica F; Lamba, Simona S; Corti, Giorgio G; Degasperi, Andrea A; Cancelliere, Carlotta C; Mauri, Gianluca G; Andrei, Pietro P; Linnebacher, Michael M; Marsoni, Silvia S; Siena, Salvatore S; Sartore-Bianchi, Andrea A; Nik-Zainal, Serena S; Di Nicolantonio, Federica F; Bardelli, Alberto A; Arena, Sabrina S

Publication Date: 2022-09-01

Variant appearance in text: PIK3CA: G12V

PubMed Link: 35881546

Variant Present in the following documents:

• EMS151756-supplement-Table_S1.xlsx, sheet 1

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Metalloprotease ADAM9 cleaves ephrin-B ligands and differentially regulates Wnt and mTOR signaling downstream of Akt kinase in colorectal cancer cells.

The Journal Of Biological Chemistry

Chandrasekera, Pathirennehelage P; Perfetto, Mark M; Lu, Congyu C; Zhuo, Minghui M; Bahudhanapati, Harinath H; Li, Jiejing J; Chen, Wei-Chih WC; Kulkarni, Pallavi P; Christian, Laura L; Liu, Jun J; Yien, Yvette Y YY; Yu, Chundong C; Wei, Shuo S

Publication Date: 2022-08

Variant appearance in text: PIK3CA: G12V

PubMed Link: 35780836

Variant Present in the following documents:

• mmc1.pdf

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HypoxaMIRs: Key Regulators of Hallmarks of Colorectal Cancer.

Cells

Coronel-Hernández, Jossimar J; Delgado-Waldo, Izamary I; Cantú de León, David D; López-Camarillo, César C; Jacobo-Herrera, Nadia N; Ramos-Payán, Rosalío R; Pérez-Plasencia, Carlos C

Publication Date: 2022-06-11

Variant appearance in text: PI3K: G12V

PubMed Link: 35741024

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• Main text
• cells-11-01895.pdf

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Aberrant expression of GSTM5 in lung adenocarcinoma is associated with DNA hypermethylation and poor prognosis.

Bmc Cancer

Hao, Xuewei X; Zhang, Jun J; Chen, Guoyou G; Cao, Weiwei W; Chen, Hongyang H; Chen, Shuo S

Publication Date: 2022-06-21

Variant appearance in text: PIK3CA: G12V

PubMed Link: 35729618

Variant Present in the following documents:

• 12885_2022_9711_MOESM3_ESM.xlsx, sheet 1

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Telomere Targeting Approaches in Cancer: Beyond Length Maintenance.

International Journal Of Molecular Sciences

Vertecchi, Eleonora E; Rizzo, Angela A; Salvati, Erica E

Publication Date: 2022-03-29

Variant appearance in text: PI3K: G12V

PubMed Link: 35409143

Variant Present in the following documents:

• ijms-23-03784.pdf

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Suppressive effect of α-mangostin for cancer stem cells in colorectal cancer via the Notch pathway.

Bmc Cancer

Jo, Min Kyoung MK; Moon, Chang Mo CM; Kim, Eun Ju EJ; Kwon, Ji-Hee JH; Fei, Xiang X; Kim, Seong-Eun SE; Jung, Sung-Ae SA; Kim, Minsuk M; Mun, Yeung-Chul YC; Ahn, Young-Ho YH; Seo, Seung-Yong SY; Kim, Tae Il TI

Publication Date: 2022-03-29

Variant appearance in text: PIK3CA: G12V

PubMed Link: 35351071

Variant Present in the following documents:

• Main text
• 12885_2022_Article_9414.pdf

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Neoantigen: A Promising Target for the Immunotherapy of Colorectal Cancer.

Disease Markers

Zheng, Yue Y; Fu, Yang Y; Wang, Pei-Pei PP; Ding, Zhen-Yu ZY

Publication Date: 2022

Variant appearance in text: PIK3CA: G12V

PubMed Link: 35211210

Variant Present in the following documents:

• DM2022-8270305.pdf

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Targeting Nutrient Dependency in Cancer Treatment.

Frontiers In Oncology

Fan, Kexin K; Liu, Zhan Z; Gao, Min M; Tu, Kangsheng K; Xu, Qiuran Q; Zhang, Yilei Y

Publication Date: 2022

Variant appearance in text: PI3K: G12V

PubMed Link: 35178349

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Spatiotemporal dynamics of clonal selection and diversification in normal endometrial epithelium.

Nature Communications

Yamaguchi, Manako M; Nakaoka, Hirofumi H; Suda, Kazuaki K; Yoshihara, Kosuke K; Ishiguro, Tatsuya T; Yachida, Nozomi N; Saito, Kyota K; Ueda, Haruka H; Sugino, Kentaro K; Mori, Yutaro Y; Yamawaki, Kaoru K; Tamura, Ryo R; Revathidevi, Sundaramoorthy S; Motoyama, Teiichi T; Tainaka, Kazuki K; Verhaak, Roel G W RGW; Inoue, Ituro I; Enomoto, Takayuki T

Publication Date: 2022-02-17

Variant appearance in text: PIK3CA: G12V

PubMed Link: 35177608

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• 41467_2022_Article_28568.pdf

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Major Molecular Signaling Pathways in Oral Cancer Associated With Therapeutic Resistance.

Frontiers In Oral Health

Usman, Saima S; Jamal, Ahmad A; Teh, Muy-Teck MT; Waseem, Ahmad A

Publication Date: 2020

Variant appearance in text: PI3K: G12V

PubMed Link: 35047986

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How can same-gene mutations promote both cancer and developmental disorders?

Science Advances

Nussinov, Ruth R; Tsai, Chung-Jung CJ; Jang, Hyunbum H

Publication Date: 2022-01-14

Variant appearance in text: PI3K: G12V

PubMed Link: 35030014

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• Main text
• sciadv.abm2059.pdf

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How can same-gene mutations promote both cancer and developmental disorders?

Science Advances

Nussinov, Ruth R; Tsai, Chung-Jung CJ; Jang, Hyunbum H

Publication Date: 2022-01-14

Variant appearance in text: PI3K: G12V

PubMed Link: 35030014

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• Main text
• sciadv.abm2059.pdf

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Comparison of Two Blood-Based Genotyping Tests to Investigate the KRAS G12C Mutation in Patients with Non-Small-Cell Lung Cancer at Failure of First-Line Treatments.

Diagnostics (Basel, Switzerland)

Nicolazzo, Chiara C; Gelibter, Alain A; Bottillo, Irene I; Belardinilli, Francesca F; Pisegna, Simona S; De Renzi, Gianluigi G; Marinelli, Daniele D; Grammatico, Paola P; Cortesi, Enrico E; Giannini, Giuseppe G; Gazzaniga, Paola P

Publication Date: 2021-11-25

Variant appearance in text: PI3K: G12V

PubMed Link: 34943432

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Targeting RAS phosphorylation in cancer therapy: Mechanisms and modulators.

Acta Pharmaceutica Sinica. B

Qiu, Yuran Y; Wang, Yuanhao Y; Chai, Zongtao Z; Ni, Duan D; Li, Xinyi X; Pu, Jun J; Chen, Jie J; Zhang, Jian J; Lu, Shaoyong S; Lv, Chuan C; Ji, Mingfei M

Publication Date: 2021-11

Variant appearance in text: PI3K: G12V

PubMed Link: 34900528

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The Adroitness of Andrographolide as a Natural Weapon Against Colorectal Cancer.

Frontiers In Pharmacology

Paul, Silpita S; Roy, Dia D; Pati, Subhadip S; Sa, Gaurisankar G

Publication Date: 2021

Variant appearance in text: PI3K: G12V

PubMed Link: 34795581

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• Main text
• fphar-12-731492.pdf

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Genome-scale CRISPR-Cas9 knockout screening in hepatocellular carcinoma with lenvatinib resistance.

Cell Death Discovery

Lu, Yonggang Y; Shen, Haoming H; Huang, Wenjie W; He, Sha S; Chen, Jianlin J; Zhang, Di D; Shen, Yongqi Y; Sun, Yifan Y

Publication Date: 2021-11-18

Variant appearance in text: PI3K: G12V

PubMed Link: 34795217

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TMEM116 is required for lung cancer cell motility and metastasis through PDK1 signaling pathway.

Cell Death & Disease

Zhang, Suhong S; Dai, Haiting H; Li, Wenya W; Wang, Runming R; Wu, Hanyu H; Shen, Ming M; Hu, Ye Y; Xie, Lixin L; Xing, Yiming Y

Publication Date: 2021-11-16

Variant appearance in text: PI3K: G12V

PubMed Link: 34789718

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Neuroblastoma signalling models unveil combination therapies targeting feedback-mediated resistance.

Plos Computational Biology

Dorel, Mathurin M; Klinger, Bertram B; Mari, Tommaso T; Toedling, Joern J; Blanc, Eric E; Messerschmidt, Clemens C; Nadler-Holly, Michal M; Ziehm, Matthias M; Sieber, Anja A; Hertwig, Falk F; Beule, Dieter D; Eggert, Angelika A; Schulte, Johannes H JH; Selbach, Matthias M; Blüthgen, Nils N

Publication Date: 2021-11

Variant appearance in text: PI3K: G12V

PubMed Link: 34735429

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Akt-mediated Ephexin1-Ras interaction promotes oncogenic Ras signaling and colorectal and lung cancer cell proliferation.

Cell Death & Disease

Kim, Jeeho J; Jeon, Young Jin YJ; Lim, Sung-Chul SC; Ryu, Joohyun J; Lee, Jung-Hee JH; Chang, In-Youb IY; You, Ho Jin HJ

Publication Date: 2021-10-28

Variant appearance in text: PI3K: G12V

PubMed Link: 34711817

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Progress on Ras/MAPK Signaling Research and Targeting in Blood and Solid Cancers.

Cancers

Dillon, Martha M; Lopez, Antonio A; Lin, Edward E; Sales, Dominic D; Perets, Ron R; Jain, Pooja P

Publication Date: 2021-10-10

Variant appearance in text: PI3K: G12V

PubMed Link: 34680208

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Diverse 'just-right' levels of chromosomal instability and their clinical implications in neoadjuvant treated gastric cancer.

British Journal Of Cancer

Kohlruss, Meike M; Krenauer, Marie M; Grosser, Bianca B; Pfarr, Nicole N; Jesinghaus, Moritz M; Slotta-Huspenina, Julia J; Novotny, Alexander A; Hapfelmeier, Alexander A; Schmidt, Thomas T; Steiger, Katja K; Gaida, Matthias M MM; Reiche, Magdalena M; Bauer, Lukas L; Ott, Katja K; Weichert, Wilko W; Keller, Gisela G

Publication Date: 2021-12

Variant appearance in text: PIK3CA: 35G>T; G12V

PubMed Link: 34671125

Variant Present in the following documents:

• 41416_2021_1587_MOESM1_ESM.pdf

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Atrophy of White Adipose Tissue Accompanied with Decreased Insulin-Stimulated Glucose Uptake in Mice Lacking the Small GTPase Rac1 Specifically in Adipocytes.

International Journal Of Molecular Sciences

Hasegawa, Kiko K; Takenaka, Nobuyuki N; Tanida, Kenya K; Chan, Man Piu MP; Sakata, Mizuki M; Aiba, Atsu A; Satoh, Takaya T

Publication Date: 2021-10-05

Variant appearance in text: PI3K: G12V

PubMed Link: 34639094

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A structural model of a Ras-Raf signalosome.

Nature Structural & Molecular Biology

Mysore, Venkatesh P VP; Zhou, Zhi-Wei ZW; Ambrogio, Chiara C; Li, Lianbo L; Kapp, Jonas N JN; Lu, Chunya C; Wang, Qi Q; Tucker, Maxwell R MR; Okoro, Jeffrey J JJ; Nagy-Davidescu, Gabriela G; Bai, Xiaochen X; Plückthun, Andreas A; Jänne, Pasi A PA; Westover, Kenneth D KD; Shan, Yibing Y; Shaw, David E DE

Publication Date: 2021-10

Variant appearance in text: PI3K: G12V

PubMed Link: 34625747

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Cyclin-dependent kinases-based synthetic lethality: Evidence, concept, and strategy.

Acta Pharmaceutica Sinica. B

Li, Kailin K; You, Jieqiong J; Wu, Qian Q; Meng, Wen W; He, Qiaojun Q; Yang, Bo B; Zhu, Chengliang C; Cao, Ji J

Publication Date: 2021-09

Variant appearance in text: PI3K: G12V

PubMed Link: 34589394

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Research and Clinical Landscape of Bispecific Antibodies for the Treatment of Solid Malignancies.

Pharmaceuticals (Basel, Switzerland)

Antonarelli, Gabriele G; Giugliano, Federica F; Corti, Chiara C; Repetto, Matteo M; Tarantino, Paolo P; Curigliano, Giuseppe G

Publication Date: 2021-08-31

Variant appearance in text: PI3K: G12V

PubMed Link: 34577584

Variant Present in the following documents:

• Main text
• pharmaceuticals-14-00884.pdf

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Tumor organoids for cancer research and personalized medicine.

Cancer Biology & Medicine

Yang, Hui H; Wang, Yinuo Y; Wang, Peng P; Zhang, Ning N; Wang, Pengyuan P

Publication Date: 2021-09-14

Variant appearance in text: PIK3CA: G12V

PubMed Link: 34520134

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Visualizing endogenous Rho activity with an improved localization-based, genetically encoded biosensor.

Journal Of Cell Science

Mahlandt, Eike K EK; Arts, Janine J G JJG; van der Meer, Werner J WJ; van der Linden, Franka H FH; Tol, Simon S; van Buul, Jaap D JD; Gadella, Theodorus W J TWJ; Goedhart, Joachim J

Publication Date: 2021-09-01

Variant appearance in text: PI3K: G12V

PubMed Link: 34357388

Variant Present in the following documents:

• joces-134-258823_review_history.pdf

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The Importance of Being PI3K in the RAS Signaling Network.

Genes

Cuesta, Cristina C; Arévalo-Alameda, Cristina C; Castellano, Esther E

Publication Date: 2021-07-19

Variant appearance in text: PI3K: G12V

PubMed Link: 34356110

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Inhibition of Calcineurin/NFAT Signaling Blocks Oncogenic H-Ras Induced Autophagy in Primary Human Keratinocytes.

Frontiers In Cell And Developmental Biology

Wang, Shuangshuang S; Qian, Hua H; Zhang, Liwei L; Liu, Panpan P; Zhuang, Dexuan D; Zhang, Qun Q; Bai, Fuxiang F; Wang, Zhihong Z; Yan, Yonggan Y; Guo, Jing J; Huang, Jun J; Wu, Xunwei X

Publication Date: 2021

Variant appearance in text: PI3K: G12V

PubMed Link: 34350189

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Forty-five years of cGMP research in Dictyostelium: understanding the regulation and function of the cGMP pathway for cell movement and chemotaxis.

Molecular Biology Of The Cell

van Haastert, Peter J M PJM; Keizer-Gunnink, Ineke I; Pots, Henderikus H; Ortiz-Mateos, Claudia C; Veltman, Douwe D; van Egmond, Wouter W; Kortholt, Arjan A

Publication Date: 2021-10-01

Variant appearance in text: PI3K: G12V

PubMed Link: 34347507

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Forty-five years of cGMP research in Dictyostelium: understanding the regulation and function of the cGMP pathway for cell movement and chemotaxis.

Molecular Biology Of The Cell

van Haastert, Peter J M PJM; Keizer-Gunnink, Ineke I; Pots, Henderikus H; Ortiz-Mateos, Claudia C; Veltman, Douwe D; van Egmond, Wouter W; Kortholt, Arjan A

Publication Date: 2021-10-01

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PubMed Link: 34347507

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Divergent Mechanisms Activating RAS and Small GTPases Through Post-translational Modification.

Frontiers In Molecular Biosciences

Osaka, Natsuki N; Hirota, Yoshihisa Y; Ito, Doshun D; Ikeda, Yoshiki Y; Kamata, Ryo R; Fujii, Yuki Y; Chirasani, Venkat R VR; Campbell, Sharon L SL; Takeuchi, Koh K; Senda, Toshiya T; Sasaki, Atsuo T AT

Publication Date: 2021

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PubMed Link: 34307463

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• fmolb-08-707439.pdf

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From Pinocytosis to Methuosis-Fluid Consumption as a Risk Factor for Cell Death.

Frontiers In Cell And Developmental Biology

Ritter, Markus M; Bresgen, Nikolaus N; Kerschbaum, Hubert H HH

Publication Date: 2021

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PubMed Link: 34249909

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Ras Isoforms from Lab Benches to Lives-What Are We Missing and How Far Are We?

International Journal Of Molecular Sciences

Nair, Arathi A; Kubatzky, Katharina F KF; Saha, Bhaskar B

Publication Date: 2021-06-17

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PubMed Link: 34204435

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The Warburg effect as a therapeutic target for bladder cancers and intratumoral heterogeneity in associated molecular targets.

Cancer Science

Burns, Julie E JE; Hurst, Carolyn D CD; Knowles, Margaret A MA; Phillips, Roger M RM; Allison, Simon J SJ

Publication Date: 2021-09

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PubMed Link: 34181805

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• CAS-112-3822-s004.xlsx, sheet 1

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A computational method for prioritizing targeted therapies in precision oncology: performance analysis in the SHIVA01 trial.

Npj Precision Oncology

Petak, Istvan I; Kamal, Maud M; Dirner, Anna A; Bieche, Ivan I; Doczi, Robert R; Mariani, Odette O; Filotas, Peter P; Salomon, Anne A; Vodicska, Barbara B; Servois, Vincent V; Varkondi, Edit E; Gentien, David D; Tihanyi, Dora D; Tresca, Patricia P; Lakatos, Dora D; Servant, Nicolas N; Deri, Julia J; du Rusquec, Pauline P; Hegedus, Csilla C; Bello Roufai, Diana D; Schwab, Richard R; Dupain, Celia C; Valyi-Nagy, Istvan T IT; Le Tourneau, Christophe C

Publication Date: 2021-06-23

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PubMed Link: 34162980

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• 41698_2021_191_MOESM7_ESM.xlsx, sheet 1

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Estrogen receptor-α signaling in post-natal mammary development and breast cancers.

Cellular And Molecular Life Sciences : Cmls

Rusidzé, Mariam M; Adlanmérini, Marine M; Chantalat, Elodie E; Raymond-Letron, I I; Cayre, Surya S; Arnal, Jean-François JF; Deugnier, Marie-Ange MA; Lenfant, Françoise F

Publication Date: 2021-08

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PubMed Link: 34156490

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Overexpression of Multifunctional Protein p32 Promotes a Malignant Phenotype in Colorectal Cancer Cells.

Frontiers In Oncology

Egusquiza-Alvarez, Carlos Alejandro CA; Castañeda-Patlán, M Cristina MC; Albarran-Gutierrez, Sara S; Gonzalez-Aguilar, Héctor H; Moreno-Londoño, Angela P AP; Maldonado, Vilma V; Melendez-Zajgla, Jorge J; Robles-Flores, Martha M

Publication Date: 2021

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PubMed Link: 34136383

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PRMT5-mediated arginine methylation activates AKT kinase to govern tumorigenesis.

Nature Communications

Yin, Shasha S; Liu, Liu L; Brobbey, Charles C; Palanisamy, Viswanathan V; Ball, Lauren E LE; Olsen, Shaun K SK; Ostrowski, Michael C MC; Gan, Wenjian W

Publication Date: 2021-06-08

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PubMed Link: 34103528

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SEMMs: Somatically Engineered Mouse Models. A New Tool for In Vivo Disease Modeling for Basic and Translational Research.

Frontiers In Oncology

Lima, Anthony A; Maddalo, Danilo D

Publication Date: 2021

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PubMed Link: 33968774

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