Publications:

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Structure-Activity Relationship Studies Based on Quinazoline Derivatives as EGFR Kinase Inhibitors (2017-Present).

Pharmaceuticals (Basel, Switzerland)

Șandor, Alexandru A; Ionuț, Ioana I; Marc, Gabriel G; Oniga, Ilioara I; Eniu, Dan D; Oniga, Ovidiu O

Publication Date: 2023-04-03

Variant appearance in text: PI3K: R19del

PubMed Link: 37111291

Variant Present in the following documents:

• pharmaceuticals-16-00534.pdf

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Resistance to TKIs in EGFR-Mutated Non-Small Cell Lung Cancer: From Mechanisms to New Therapeutic Strategies.

Cancers

Koulouris, Andreas A; Tsagkaris, Christos C; Corriero, Anna Chiara AC; Metro, Giulio G; Mountzios, Giannis G

Publication Date: 2022-07-08

Variant appearance in text: PIK3CA: R19del

PubMed Link: 35884398

Variant Present in the following documents:

• Main text
• cancers-14-03337.pdf

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Anlotinib Downregulates RGC32 Which Provoked by Bevacizumab.

Frontiers In Oncology

Liu, Zhujun Z; Qin, Tingting T; Yuan, Xiaohan X; Yang, Jie J; Shi, Wei W; Zhang, Xiaoling X; Jia, Yanan Y; Liu, Shaochuan S; Wang, Jing J; Li, Kai K

Publication Date: 2022

Variant appearance in text: PI3K: R19del

PubMed Link: 35664796

Variant Present in the following documents:

• fonc-12-875888.pdf

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EGFR/BRAF/MEK co-inhibition for EGFR-mutated lung adenocarcinoma patients with an acquired BRAFV600E mutation: a case report and review of literature.

Cancer Drug Resistance (Alhambra, Calif.)

Zeng, Ran R; Luo, Lifeng L; Sun, Xianwen X; Bao, Zhiyao Z; Du, Wei W; Dai, Ranran R; Tang, Wei W; Gao, Beili B; Xiang, Yi Y

Publication Date: 2021

Variant appearance in text: PIK3CA: R19del

PubMed Link: 35582379

Variant Present in the following documents:

• cdr-4-1019.pdf

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LS-106, a novel EGFR inhibitor targeting C797S, exhibits antitumor activities both in vitro and in vivo.

Cancer Science

Liu, Yingqiang Y; Lai, Mengzhen M; Li, Shan S; Wang, Yanan Y; Feng, Fang F; Zhang, Tao T; Tong, Linjiang L; Zhang, Mengge M; Chen, Hao H; Chen, Yi Y; Song, Peiran P; Li, Yan Y; Bai, Gang G; Ning, Yi Y; Tang, Haotian H; Fang, Yan Y; Chen, Yi Y; Lu, Xiaoyun X; Geng, Meiyu M; Ding, Ke K; Yu, Ker K; Xie, Hua H; Ding, Jian J

Publication Date: 2022-02

Variant appearance in text: PI3K: R19del

PubMed Link: 34855271

Variant Present in the following documents:

• Main text
• CAS-113-709.pdf

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: PIK3CA: R19del

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

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Afatinib treatment response in advanced lung adenocarcinomas harboring uncommon mutations.

Thoracic Cancer

Li, Teng T; Wang, Shouzheng S; Ying, Jianming J; Wang, Yan Y; Hu, Xingsheng X; Hao, Xuezhi X; Xu, Ziyi Z; Xing, Puyuan P; Li, Junling J

Publication Date: 2021-11

Variant appearance in text: PIK3CA: R19del

PubMed Link: 34549528

Variant Present in the following documents:

• Main text
• TCA-12-2924.pdf

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Cell-Free DNA: Hope and Potential Application in Cancer.

Frontiers In Cell And Developmental Biology

Yan, Yan-Yan YY; Guo, Qiao-Ru QR; Wang, Feng-Hua FH; Adhikari, Rameshwar R; Zhu, Zhuang-Yan ZY; Zhang, Hai-Yan HY; Zhou, Wen-Min WM; Yu, Hua H; Li, Jing-Quan JQ; Zhang, Jian-Ye JY

Publication Date: 2021

Variant appearance in text: PIK3CA: R19del

PubMed Link: 33693004

Variant Present in the following documents:

• Main text
• fcell-09-639233.pdf

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ALK rearrangements as mechanisms of acquired resistance to osimertinib in EGFR mutant non-small cell lung cancer.

Thoracic Cancer

Hou, Helei H; Sun, Dantong D; Zhang, Chuantao C; Liu, Dong D; Zhang, Xiaochun X

Publication Date: 2021-03

Variant appearance in text: PI3K: R19del

PubMed Link: 33506568

Variant Present in the following documents:

• Main text
• TCA-12-962.pdf

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Predictive Biomarkers for Immune Checkpoint Inhibitors in Metastatic Breast Cancer.

Cancer Medicine

Sivapiragasam, Abirami A; Ashok Kumar, Prashanth P; Sokol, Ethan S ES; Albacker, Lee A LA; Killian, Jonathan K JK; Ramkissoon, Shakti H SH; Huang, Richard S P RSP; Severson, Eric A EA; Brown, Charlotte A CA; Danziger, Natalie N; McGregor, Kimberly K; Ross, Jeffrey S JS

Publication Date: 2021-01

Variant appearance in text: PIK3CA: R19del

PubMed Link: 33314633

Variant Present in the following documents:

• CAM4-10-53-s003.xlsx, sheet 1

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Patients with advanced non-small cell lung cancer with EGFR mutations in addition to complex mutations treated with osimertinib have a poor clinical outcome: A real-world data analysis.

Oncology Letters

Chang, Nijia N; Duan, Jingjing J; Wang, Lingxiong L; Dong, Zhouhuan Z; Liu, Zhefeng Z

Publication Date: 2020-09

Variant appearance in text: PIK3CA: R19del

PubMed Link: 32782544

Variant Present in the following documents:

• Main text
• ol-20-03-2266.pdf

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Mechanisms of resistance to osimertinib.

Journal Of Thoracic Disease

Lazzari, Chiara C; Gregorc, Vanesa V; Karachaliou, Niki N; Rosell, Rafael R; Santarpia, Mariacarmela M

Publication Date: 2020-05

Variant appearance in text: PIK3CA: R19del

PubMed Link: 32642198

Variant Present in the following documents:

• Main text
• jtd-12-05-2851.pdf

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Phase and context shape the function of composite oncogenic mutations.

Nature

Gorelick, Alexander N AN; Sánchez-Rivera, Francisco J FJ; Cai, Yanyan Y; Bielski, Craig M CM; Biederstedt, Evan E; Jonsson, Philip P; Richards, Allison L AL; Vasan, Neil N; Penson, Alexander V AV; Friedman, Noah D ND; Ho, Yu-Jui YJ; Baslan, Timour T; Bandlamudi, Chaitanya C; Scaltriti, Maurizio M; Schultz, Nikolaus N; Lowe, Scott W SW; Reznik, Ed E; Taylor, Barry S BS

Publication Date: 2020-06

Variant appearance in text: PIK3CA: R19del

PubMed Link: 32461694

Variant Present in the following documents:

• NIHMS1582596-supplement-1582596_Supp_Tab1-5.xlsx, sheet 2

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Combined plasma and tissue genotyping of EGFR T790M benefits NSCLC patients: a real-world clinical example.

Molecular Oncology

Wei, Bing B; Zhao, Chengzhi C; Li, Jun J; Zhao, Jiuzhou J; Ren, Pengfei P; Yang, Ke K; Yan, Chi C; Sun, Rui R; Ma, Jie J; Guo, Yongjun Y

Publication Date: 2019-05

Variant appearance in text: PIK3CA: R19del

PubMed Link: 30927306

Variant Present in the following documents:

• MOL2-13-1226.pdf

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JAK2 inhibitor TG101348 overcomes erlotinib-resistance in non-small cell lung carcinoma cells with mutated EGF receptor.

Oncotarget

Zhang, Fu-quan FQ; Yang, Wen-tao WT; Duan, Shan-zhou SZ; Xia, Ying-chen YC; Zhu, Rong-ying RY; Chen, Yong-bing YB

Publication Date: 2015-06-10

Variant appearance in text: PI3K: R19del

PubMed Link: 25869210

Variant Present in the following documents:

• oncotarget-06-14329.pdf

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